Substrates of Factor XIII-A: roles in thrombosis and wound healing

scientific article published on February 2013

Substrates of Factor XIII-A: roles in thrombosis and wound healing is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/CS20120233
P698PubMed publication ID23075332

P2093author name stringAngela M Carter
Victoria R Richardson
Kristina F Standeven
Paul Cordell
P2860cites workBiochemistry and genetics of von Willebrand factorQ22003890
Three-dimensional structure of a transglutaminase: human blood coagulation factor XIIIQ24564521
Role of factor XIII in fibrin clot formation and effects of genetic polymorphismsQ28215367
Amino acid sequence studies on factor XIII and the peptide released during its activation by thrombinQ28245806
Tissue transglutaminase and its substrates in boneQ28573074
Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosisQ28589061
Regulation of formation of factor XIIIa by its fibrin substratesQ28630691
Factor XIII: novel structural and functional aspectsQ30156007
Transglutaminase factor XIII uses proteinase-like catalytic triad to crosslink macromoleculesQ30419776
Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics.Q30997344
Screening for the preferred substrate sequence of transglutaminase using a phage-displayed peptide library: identification of peptide substrates for TGASE 2 and Factor XIIIA.Q33240965
Does FXIII deficiency impair wound healing after myocardial infarction?Q33267305
Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretionQ33387901
Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysisQ41904806
Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation.Q41994357
Reversible activation of cellular factor XIII by calciumQ42103946
Analysis of transglutaminase protein substrates by functional proteomics.Q42141647
The antifibrinolytic function of factor XIII is exclusively expressed through α₂-antiplasmin cross-linking.Q42326716
Thrombospondin-1 induces platelet activation through CD36-dependent inhibition of the cAMP/protein kinase A signaling cascade.Q42955265
Impaired clot retraction in factor XIII A subunit-deficient miceQ43227254
Stimulated platelets use serotonin to enhance their retention of procoagulant proteins on the cell surfaceQ43863360
Structural features associated with the binding of glutamine-containing peptides to Factor XIII.Q44137984
Thrombospondin and fibrinogen bind serotonin-derivatized proteins on COAT-plateletsQ44155386
Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombiQ44947010
Molecular mechanism of the interaction between activated factor XIII and its glutamine donor peptide substrateQ46134154
Identification of factor-XIIIa-reactive glutaminyl residues in the propolypeptide of bovine von Willebrand factor.Q46201054
Megakaryocyte-matrix interaction within bone marrow: new roles for fibronectin and factor XIII-A.Q46501234
Clinico-hematologic profile of factor XIII-deficient patientsQ46770303
Osteopontin, a substrate for transglutaminase and Factor XIII activityQ46850555
Vinculin is a permanent component of the membrane skeleton and is incorporated into the (re)organising cytoskeleton upon platelet activationQ46877736
Platelets but not monocytes contribute to the plasma levels of factor XIII subunit A in patients undergoing autologous peripheral blood stem cell transplantationQ47832026
Complement C3 is a novel plasma clot component with anti-fibrinolytic properties.Q52844285
Functional analysis of the fibrinogen Aalpha Thr312Ala polymorphism: effects on fibrin structure and function.Q52860308
Fibrin gel structure: influence of calcium and covalent cross-linking on the elasticity.Q54288649
Dissociation of the subunit structure of fibrin stabilizing factor during activation of the zymogen.Q54325655
Incorporation of vitronectin into fibrin clots. Evidence for a binding interaction between vitronectin and gamma A/gamma' fibrinogen.Q54441943
Factor XIII-mediated cross-linking of NH2-terminal peptide of alpha 2-plasmin inhibitor to fibrin.Q54787975
Novel Factor XIII Probes for Blood Coagulation ImagingQ58816212
Sensitive and selective detection of free FXIII activation peptide: a potential marker of acute thrombotic eventsQ33550678
Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarctionQ33789267
alpha(2)-plasmin inhibitor is a substrate for tissue transglutaminase: an in vitro studyQ33915670
Fibronectin at a glanceQ34150530
Amino acid sequence studies on the .alpha. chain of human fibrinogen. Exact location of crosslinking acceptor sitesQ34229561
Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis.Q34307809
Binding and covalent cross-linking of purified von Willebrand factor to native monomeric collagenQ34534629
Identification of intracellular factor XIII in human monocytes and macrophagesQ34548038
Enhancement of thrombogenesis by plasma fibronectin cross-linked to fibrin and assembled in platelet thrombiQ34591264
TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clotsQ34612650
Amino acid sequence of the factor XIIIa acceptor site in bovine plasma fibronectinQ34707148
Contribution of fibrin stabilization to clot strength. Supplementation of factor XIII-deficient plasma with the purified zymogenQ35206931
Cross-linked gamma-chains in fibrin fibrils bridge 'transversely' between strands: yes.Q35686021
Cross-linked gamma-chains in fibrin fibrils bridge transversely between strands: no.Q35686026
The complementary aggregation sites of fibrin investigated through examination of polymers of fibrinogen with fragment E.Q35863142
Alpha2-antiplasmin: potential therapeutic roles in fibrin survival and removalQ35867311
Fibrinogen and fibrin.Q36101288
The molecular physiology and pathology of fibrin structure/functionQ36166852
Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalizationQ36255694
Coated-platelets: an emerging component of the procoagulant responseQ36272167
Transglutaminases in mineralized tissuesQ36348212
The sequence of cleavage of fibrinopeptides from fibrinogen is important for protofibril formation and enhancement of lateral aggregation in fibrin clotsQ36764995
Cross-linking of alpha 2-plasmin inhibitor to fibrin by fibrin-stabilizing factorQ37020020
Cross-linking of fibronectin to collagen by blood coagulation Factor XIIIaQ37041474
The location of the carboxy-terminal region of gamma chains in fibrinogen and fibrin D domainsQ37472679
Fibronectin: structure, function and significance in wound healingQ37781856
Covalent cross-linking of fibronectin to fibrin is required for maximal cell adhesion to a fibronectin-fibrin matrixQ38342850
New insights into the expression and role of platelet factor XIII-A.Q38354356
Factor XIIIa-catalyzed cross-linking of recombinant alpha C fragments of human fibrinogen.Q38357934
Identification of respective lysine donor and glutamine acceptor sites involved in factor XIIIa-catalyzed fibrin α chain cross-linkingQ40042347
Expression and localization of plasma transglutaminase factor XIIIA in bone.Q40162733
Transglutaminase activity regulates osteoblast differentiation and matrix mineralization in MC3T3-E1 osteoblast cultures.Q40318405
Fibronectin: review of its structure and possible functionsQ40354659
Proteomics identification of acyl-acceptor and acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. Implications for celiac diseaseQ40640779
Alpha2-plasmin inhibitor and alpha2-macroglobulin-plasmin complexes in plasma. Quantitation by an enzyme-linked differential antibody immunosorbent assayQ40683743
Significance of cross-linking of alpha 2-plasmin inhibitor to fibrin in inhibition of fibrinolysis and in hemostasisQ40684825
Identification of the alpha chain lysine donor sites involved in factor XIIIa fibrin cross-linkingQ40930403
Tissue transglutaminase and factor XIII in cartilage and bone remodelingQ41302285
Fibrinoligase-catalyzed cross-linking of myosin from platelet and skeletal muscleQ41538985
Localization of transglutaminase-reactive glutamine residues in bovine osteopontin.Q41770359
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectthrombosisQ261327
wound healingQ1509074
P304page(s)123-137
P577publication date2013-02-01
P1433published inClinical ScienceQ372419
P1476titleSubstrates of Factor XIII-A: roles in thrombosis and wound healing
P478volume124

Reverse relations

cites work (P2860)
Q37292431Airway factor XIII associates with type 2 inflammation and airway obstruction in asthmatic patients
Q36088633Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.
Q38562231Characterization of a novel large deletion caused by double-stranded breaks in 6-bp microhomologous sequences of intron 11 and 12 of the F13A1 gene
Q41825512Coagulation factor XIIIa substrates in human plasma: identification and incorporation into the clot
Q89585538Dynamics of coagulation factor XIII activity after video-assisted thoracoscopic lobectomy for non-small cell lung cancer
Q88104986Expression of Coagulation Factor XIII Subunit A Correlates with Outcome in Childhood Acute Lymphoblastic Leukemia
Q35670403Factor XIII Transglutaminase Supports the Resolution of Mucosal Damage in Experimental Colitis
Q58763233Factor XIII polymorphism and risk of aneurysmal subarachnoid haemorrhage in a south Indian population
Q38561435Immune-mediated pathology in Duchenne muscular dystrophy
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Q86590807Longitudinal orientation of cross-linked polypeptide γ chains in fibrin fibrils
Q28077583Molecular Cues Guiding Matrix Stiffness in Liver Fibrosis
Q91964348Prognostic significance of factor XIIIA promoter methylation status in aneurysmal subarachnoid haemorrhage (aSAH)
Q26739684Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for blood clotting
Q35156659Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers.
Q35948493Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII.
Q34481558SOD1 nanozyme salvages ischemic brain by locally protecting cerebral vasculature.
Q92432047Structure functional insights into calcium binding during the activation of coagulation factor XIII A
Q40827724The activation peptide of coagulation factor XIII is vital for its expression and stability.
Q90316811The multifaceted role of fibrinogen in tissue injury and inflammation
Q34974033Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion

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