review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1031306051 |
P356 | DOI | 10.1038/NRC3396 |
P698 | PubMed publication ID | 23192231 |
P50 | author | Vincent Giguère | Q30089966 |
P2093 | author name string | Geneviève Deblois | |
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Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle | Q24564824 | ||
The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis | Q24564869 | ||
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ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. | Q51579173 | ||
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The interplay between MYC and HIF in cancer. | Q53513869 | ||
The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload. | Q55044173 | ||
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Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism | Q27645400 | ||
Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2 | Q28140298 | ||
Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha | Q28218141 | ||
X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation | Q28264769 | ||
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells | Q28275988 | ||
An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha | Q28282893 | ||
Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha | Q28290106 | ||
Modulation of aromatase expression in the breast tissue by ERR alpha-1 orphan receptor | Q28292335 | ||
Identification of a new class of steroid hormone receptors | Q28294293 | ||
Regulation of cancer cell metabolism | Q28303890 | ||
4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma | Q28343744 | ||
Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta | Q28362262 | ||
Dissecting self-renewal in stem cells with RNA interference | Q28506922 | ||
The orphan nuclear estrogen receptor-related receptor alpha (ERRalpha) is expressed throughout osteoblast differentiation and regulates bone formation in vitro | Q28580424 | ||
Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta | Q28591718 | ||
Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming | Q28910179 | ||
Constitutive Activation of Transcription and Binding of Coactivator by Estrogen-Related Receptors 1 and 2 | Q29039763 | ||
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells | Q29547179 | ||
Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis | Q29568481 | ||
On respiratory impairment in cancer cells | Q29617276 | ||
Otto Warburg's contributions to current concepts of cancer metabolism | Q29617601 | ||
Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions | Q33260963 | ||
Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif | Q33643260 | ||
Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway | Q33670484 | ||
Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression | Q33766811 | ||
Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer | Q34181456 | ||
Recent advance in the design of small molecular modulators of estrogen-related receptors. | Q34283013 | ||
Transcriptional amplification in tumor cells with elevated c-Myc. | Q34302542 | ||
MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cells | Q34314172 | ||
Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity | Q34322874 | ||
WNT11 Expression Is Induced by Estrogen-Related Receptor α and β-Catenin and Acts in an Autocrine Manner to Increase Cancer Cell Migration | Q39651531 | ||
The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions | Q39691060 | ||
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. | Q39814340 | ||
Estrogen-related receptor alpha expression and function is associated with the transcriptional coregulator AIB1 in breast carcinoma | Q39843631 | ||
Modulation of adipogenesis-related gene expression by estrogen-related receptor gamma during adipocytic differentiation. | Q39937084 | ||
The significance of the expression of ERRalpha as a potential biomarker in breast cancer | Q40010856 | ||
Epidermal growth factor-induced signaling in breast cancer cells results in selective target gene activation by orphan nuclear receptor estrogen-related receptor alpha | Q40396885 | ||
Identification of an agonist ligand for estrogen-related receptors ERRbeta/gamma. | Q40458060 | ||
The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha). | Q40678460 | ||
Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity | Q42502907 | ||
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. | Q42723877 | ||
Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents | Q42759813 | ||
The tyrosine kinase receptor HER2 (erbB-2): from oncogenesis to adipogenesis | Q42808101 | ||
Transcriptional regulation of the estrogen-inducible pS2 breast cancer marker gene by the ERR family of orphan nuclear receptors | Q43739428 | ||
4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related (ERR) nuclear receptors beta and gamma | Q43743283 | ||
Estrogen-related receptor alpha and estrogen-related receptor gamma associate with unfavorable and favorable biomarkers, respectively, in human breast cancer. | Q44220756 | ||
Estrogen-related receptor alpha in human breast carcinoma as a potent prognostic factor | Q44961902 | ||
Estrogen-related receptor-alpha antagonist inhibits both estrogen receptor-positive and estrogen receptor-negative breast tumor growth in mouse xenografts | Q46093148 | ||
Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma | Q46460035 | ||
Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma | Q46820185 | ||
Adaptation of energy metabolism in breast cancer brain metastases | Q48269541 | ||
A polymorphic autoregulatory hormone response element in the human estrogen-related receptor alpha (ERRalpha) promoter dictates peroxisome proliferator-activated receptor gamma coactivator-1alpha control of ERRalpha expression. | Q51024981 | ||
Selective estrogen-receptor modulators and antihormonal resistance in breast cancer | Q34692670 | ||
Estrogen-related receptor gamma promotes mesenchymal-to-epithelial transition and suppresses breast tumor growth | Q34762100 | ||
The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth. | Q34771704 | ||
Metabolic positron emission tomography imaging in cancer detection and therapy response | Q34786518 | ||
To ERR in the estrogen pathway | Q34788536 | ||
Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate | Q34836415 | ||
A century of deciphering the control mechanisms of sex steroid action in breast and prostate cancer: the origins of targeted therapy and chemoprevention | Q34942152 | ||
Estrogen-related receptor gamma (ERRgamma) mediates oxygen-dependent induction of aromatase (CYP19) gene expression during human trophoblast differentiation. | Q35193170 | ||
Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway | Q35216853 | ||
The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer | Q35421284 | ||
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation | Q35546707 | ||
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense | Q35917062 | ||
Regulation of glycolysis and the Warburg effect by estrogen-related receptors | Q36213663 | ||
The NR3B subgroup: an ovERRview | Q36238317 | ||
PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity | Q36350223 | ||
Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance | Q36472242 | ||
The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. | Q36572042 | ||
Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer | Q37079303 | ||
Estrogen-related receptor alpha induces the expression of vascular endothelial growth factor in breast cancer cells | Q37188645 | ||
Transcriptional control of energy homeostasis by the estrogen-related receptors | Q37229563 | ||
ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer | Q37240697 | ||
ERRalpha: a metabolic function for the oldest orphan | Q37263563 | ||
Modulating estrogen receptor-related receptor-alpha activity inhibits cell proliferation | Q37358073 | ||
Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives. | Q37603645 | ||
Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks | Q37865795 | ||
Targeting cancer metabolism: a therapeutic window opens | Q37924094 | ||
Estrogen-related receptor alpha (ERRalpha) is a transcriptional regulator of apolipoprotein A-IV and controls lipid handling in the intestine | Q38335798 | ||
Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity. | Q38352075 | ||
Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter | Q38360573 | ||
PGC-1α promotes the growth of ErbB2/Neu-induced mammary tumors by regulating nutrient supply | Q39408474 | ||
Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin | Q39511667 | ||
Transcriptional control of the ERBB2 amplicon by ERRalpha and PGC-1beta promotes mammary gland tumorigenesis | Q39641829 | ||
miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway | Q39648802 | ||
Estrogen-related receptor γ modulates cell proliferation and estrogen signaling in breast cancer | Q39649549 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | breast cancer | Q128581 |
P304 | page(s) | 27-36 | |
P577 | publication date | 2012-11-29 | |
P1433 | published in | Nature Reviews Cancer | Q641657 |
P1476 | title | Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond | |
P478 | volume | 13 |
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Q38232839 | A review of selected chemical additives in cosmetic products |
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Q90583561 | Cell Cycle Modulation of CHO-K1 Cells Under Genistein Treatment Correlates with Cells Senescence, Apoptosis and ROS Level but in a Dose-Dependent Manner |
Q37651068 | Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization |
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Q46346065 | Complementary Roles of Estrogen-Related Receptors in Brown Adipocyte Thermogenic Function |
Q35914934 | Controllable drug uptake and nongenomic response through estrogen-anchored cyclodextrin drug complex |
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Q38874006 | Differential Potential of Pharmacological PARP Inhibitors for Inhibiting Cell Proliferation and Inducing Apoptosis in Human Breast Cancer Cells |
Q54403267 | Distinct nuclear receptor expression in stroma adjacent to breast tumors. |
Q52609008 | Drosophila as a Model to Study the Link between Metabolism and Cancer. |
Q90280167 | Drosophila estrogen-related receptor directs a transcriptional switch that supports adult glycolysis and lipogenesis |
Q33836140 | ERK/MAPK regulates ERRγ expression, transcriptional activity and receptor-mediated tamoxifen resistance in ER+ breast cancer |
Q36693175 | ERRα Is a Marker of Tamoxifen Response and Survival in Triple-Negative Breast Cancer |
Q50952961 | ERRα Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-Elevated Melanomas. |
Q92370310 | ERRα activates SHMT2 transcription to enhance the resistance of breast cancer to lapatinib via modulating the mitochondrial metabolic adaption |
Q64071528 | ERRα as a Bridge Between Transcription and Function: Role in Liver Metabolism and Disease |
Q39034345 | ERRα augments HIF-1 signalling by directly interacting with HIF-1α in normoxic and hypoxic prostate cancer cells |
Q38872759 | ERRα induces H3K9 demethylation by LSD1 to promote cell invasion |
Q90354130 | ERRα is an aggressive factor in lung adenocarcinoma indicating poor prognostic outcomes |
Q37096669 | ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer |
Q93382185 | ERRα promotes breast cancer cell dissemination to bone by increasing RANK expression in primary breast tumors |
Q88951821 | ERRα regulates the growth of triple-negative breast cancer cells via S6K1-dependent mechanism |
Q92099958 | ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion |
Q53417438 | Emerging Roles of Estrogen-Related Receptors in the Brain: Potential Interactions with Estrogen Signaling. |
Q37170398 | Estradiol and tamoxifen regulate NRF-1 and mitochondrial function in mouse mammary gland and uterus. |
Q36413130 | Estrogen related receptor α (ERRα) a promising target for the therapy of adrenocortical carcinoma (ACC) |
Q89977016 | Estrogen-Related Receptor Alpha: An Under-Appreciated Potential Target for the Treatment of Metabolic Diseases |
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Q33701412 | Estrogen-related receptor γ serves a role in blood pressure homeostasis during pregnancy |
Q33631880 | Estrogen-related receptor-α coordinates transcriptional programs essential for exercise tolerance and muscle fitness. |
Q89588217 | Estrogen-related receptor-α promotes gallbladder cancer development by enhancing the transcription of Nectin-4 |
Q55443239 | Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma. |
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