Lipid metabolism in Drosophila: development and disease

scientific article published on January 2013

Lipid metabolism in Drosophila: development and disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1093/ABBS/GMS105
P698PubMed publication ID23257293
P5875ResearchGate publication ID233963554

P2093author name stringXun Huang
Zhonghua Liu
P2860cites workInsulin signalling and the regulation of glucose and lipid metabolismQ24292020
Homophila: human disease gene cognates in DrosophilaQ24548431
High sugar-induced insulin resistance in Drosophila relies on the lipocalin Neural LazarilloQ27303562
Insulin signaling regulates fatty acid catabolism at the level of CoA activationQ27334898
Tissue-autonomous function of Drosophila seipin in preventing ectopic lipid droplet formationQ27342499
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factorQ28238069
Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1Q28268591
A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermiaQ28943316
Wnt proteins are lipid-modified and can act as stem cell growth factorsQ29615009
Lessons from "lower" organisms: what worms, flies, and zebrafish can teach us about human energy metabolism.Q30366541
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotypeQ30493760
Phosphatidylinositol 4,5-bisphosphate directs spermatid cell polarity and exocyst localization in Drosophila.Q30494269
Lipid phosphate phosphatase activity regulates dispersal and bilateral sorting of embryonic germ cells in DrosophilaQ30494409
Coordination of triacylglycerol and cholesterol homeostasis by DHR96 and the Drosophila LipA homolog magroQ40252579
Germ cell-autonomous Wunen2 is required for germline development in Drosophila embryos.Q40485684
Soma-germ line competition for lipid phosphate uptake regulates germ cell migration and survival.Q40521784
Preventing neurodegeneration in the Drosophila mutant bubblegumQ41673343
Models of infectious diseases in the fruit fly Drosophila melanogasterQ42068811
Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics.Q42451814
Opposite and redundant roles of the two Drosophila perilipins in lipid mobilizationQ42504871
OSBP- and FAN-mediated sterol requirement for spermatogenesis inDrosophilaQ43902261
Regulation of SREBP processing and membrane lipid production by phospholipids in DrosophilaQ43978685
Ablation of insulin-producing neurons in flies: growth and diabetic phenotypesQ43988822
The lipid-droplet proteome reveals that droplets are a protein-storage depot.Q44410871
Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive functionQ44727142
Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cellsQ45062201
De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system.Q46648320
Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegenerationQ46910610
Brummer lipase is an evolutionary conserved fat storage regulator in DrosophilaQ47070072
The Drosophila phosphatidylinositol transfer protein encoded by vibrator is essential to maintain cleavage-furrow ingression in cytokinesis.Q47070579
The cytohesin Steppke is essential for insulin signalling in DrosophilaQ47070985
Wunen, a Drosophila lipid phosphate phosphatase, is required for septate junction-mediated barrier function.Q47071161
Altered lipid metabolism in a Drosophila model of Friedreich's ataxia.Q47071728
The cholesterol trafficking protein NPC1 is required for Drosophila spermatogenesis.Q47071773
The class I PITP giotto is required for Drosophila cytokinesisQ47071778
The fatty acid elongase NOA is necessary for viability and has a somatic role in Drosophila sperm developmentQ47071968
Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative diseaseQ47072010
An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth controlQ47072375
Drosophila models of peroxisomal biogenesis disorder: peroxins are required for spermatogenesis and very-long-chain fatty acid metabolismQ47072511
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ sizeQ47211341
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in DrosophilaQ30497986
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathwayQ30829981
Akt phosphorylates both Tsc1 and Tsc2 in Drosophila, but neither phosphorylation is required for normal animal growthQ33483334
The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathwayQ33493398
A Buoyancy-Based Screen of Drosophila Larvae for Fat-Storage Mutants Reveals a Role for Sir2 in Coupling Fat Storage to Nutrient AvailabilityQ33750102
Targeting the motor regulator Klar to lipid dropletsQ33829227
Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.Q33870792
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genesQ33878155
Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosisQ34079770
Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fateQ34092765
MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in DrosophilaQ34126334
Drosophila miR-14 regulates insulin production and metabolism through its target, sugarbabeQ34155071
Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicityQ34236510
Insulin signaling: lessons from the Drosophila tuberous sclerosis complex, a tumor suppressorQ34417182
Hedgehog signaling: a tale of two lipidsQ34453915
A Drosophila model of Barth syndromeQ34984428
Lipin is a central regulator of adipose tissue development and function in Drosophila melanogasterQ35077086
A high-sugar diet produces obesity and insulin resistance in wild-type DrosophilaQ35532373
Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegenerationQ35835807
Incredible journey: how do developmental signals travel through tissue?Q35985752
Disruption of sphingolipid metabolism elicits apoptosis-associated reproductive defects in Drosophila.Q36169377
Control of lateral migration and germ cell elimination by the Drosophila melanogaster lipid phosphate phosphatases Wunen and Wunen 2Q36321077
Drosophila models for cancer research.Q36344450
Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brainQ36405771
Lipid droplets control the maternal histone supply of Drosophila embryosQ36442007
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in DrosophilaQ36641874
Age-related cardiac disease model of DrosophilaQ36663066
A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytesQ36960262
Drosophila and the genetics of the internal milieuQ36997692
Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancerQ37778905
Roles of sphingolipids in Drosophila development and diseaseQ37826774
The contribution of the Drosophila model to lipid droplet researchQ37881206
The dynamic roles of intracellular lipid droplets: from archaea to mammals.Q37946280
Depletion of plasma membrane PtdIns(4,5)P2 reveals essential roles for phosphoinositides in flagellar biogenesis.Q38848293
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)44-50
P577publication date2013-01-01
P1433published inActa Biochimica et Biophysica SinicaQ2183997
P1476titleLipid metabolism in Drosophila: development and disease
P478volume45

Reverse relations

cites work (P2860)
Q52859744A Buoyancy-based Method of Determining Fat Levels in Drosophila.
Q38893703A central role for phosphatidic acid as a lipid mediator of regulated exocytosis in apicomplexa.
Q33784980A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster
Q33884515An autonomous metabolic role for Spen
Q57807817CDK8 Mediates the Dietary Effects on Developmental Transition in Drosophila
Q52844588Drosophila Fed ARA and EPA Yields Eicosanoids, 15S-Hydroxy-5Z,8Z, 11Z, 13E-Eicosatetraenoic Acid, and 15S-Hydroxy-5Z,8Z,11Z,13E,17Z-Eicosapentaenoic Acid.
Q38674524Drosophila melanogaster: An emerging model of transgenerational effects of maternal obesity
Q26822877From fat fruit fly to human obesity
Q35110559Hierarchical partitioning of metazoan protein conservation profiles provides new functional insights
Q91664370Intestinal lipid droplets as novel mediators of host-pathogen interaction in Drosophila
Q46282072Lipidomic profiles of Drosophila melanogaster and cactophilic fly species: models of human metabolic diseases
Q38646601Lipids in Insect Oocytes: From the Storage Pathways to Their Multiple Functions
Q35536431Maintenance of glia in the optic lamina is mediated by EGFR signaling by photoreceptors in adult Drosophila
Q28079836Modeling dietary influences on offspring metabolic programming in Drosophila melanogaster
Q33851570Nanopipettes: probes for local sample analysis
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Q92452494The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions
Q47656768Transcriptome Analysis of the Triatoma infestans (Hemiptera: Reduviidae) Integument

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