Dendritic protein synthesis in the normal and diseased brain

scientific article published on 20 December 2012

Dendritic protein synthesis in the normal and diseased brain is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.NEUROSCIENCE.2012.12.003
P932PMC publication ID4502914
P698PubMed publication ID23262237

P2093author name stringG J Bassell
S A Swanger
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Translational control by neuroguidin, a eukaryotic initiation factor 4E and CPEB binding proteinQ24548966
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Trading translation with RNA-binding proteinsQ24645458
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Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activationQ24657890
Facilitation of dendritic mRNA transport by CPEBQ24672622
Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neuronsQ25256777
Downregulation of tonic GABAergic inhibition in a mouse model of fragile X syndromeQ27303466
Single-molecule imaging of translational output from individual RNA granules in neuronsQ30506040
The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.Q30523244
eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memoryQ30586619
Activity-dependent polyadenylation in neuronsQ30794453
FMRP mediates mGluR5-dependent translation of amyloid precursor proteinQ33273636
Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognitionQ33572943
A genetic variant BDNF polymorphism alters extinction learning in both mouse and humanQ33690935
BDNF induces translocation of initiation factor 4E to mRNA granules: Evidence for a role of synaptic microfilaments and integrinsQ33717423
Intracellular calcium and calmodulin link brain-derived neurotrophic factor to p70S6 kinase phosphorylation and dendritic protein synthesisQ33802613
Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesisQ33819129
Ventral striatal plasticity and spatial memoryQ33842888
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampusQ33898132
Fear and safety learning differentially affect synapse size and dendritic translation in the lateral amygdala.Q33927169
Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation.Q33945996
Genetics and biology of Alzheimer's disease and frontotemporal lobar degenerationQ33951192
Upstream open reading frames as regulators of mRNA translationQ33966388
Variant BDNF (Val66Met) impact on brain structure and functionQ33997931
CPEB: a life in translationQ34003974
A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticityQ34062918
N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapsesQ34078959
Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation proteinQ34100256
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Selective localization of messenger RNA for cytoskeletal protein MAP2 in dendritesQ34169670
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RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complexQ34241749
Somatodendritic expression of an immediate early gene is regulated by synaptic activityQ34253475
The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imagingQ34266527
Pin1 and PKMzeta sequentially control dendritic protein synthesisQ34274733
Theta frequency stimulation induces a local form of late phase LTP in the CA1 region of the hippocampusQ34324384
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disordersQ34358701
D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampusQ34467913
Estrogen-induced activation of extracellular signal-regulated kinase signaling triggers dendritic resident mRNA translationQ34518905
TDP-43 in aging and Alzheimer's disease - a reviewQ34566756
Regulatory BC1 RNA and the fragile X mental retardation protein: convergent functionality in brainQ27312243
A novel function for fragile X mental retardation protein in translational activationQ28118268
Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation proteinQ28119013
Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memoryQ28186778
Rapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memoryQ28202260
Internal ribosome entry sites in eukaryotic mRNA moleculesQ28205551
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapsesQ28208647
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathwayQ28236951
TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factorQ28261458
Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neuronsQ28266983
Upstream and downstream of mTORQ28277365
P bodies: at the crossroads of post-transcriptional pathwaysQ28280058
TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spinesQ28284342
Fragile X protein controls the efficacy of mRNA transport in Drosophila neuronsQ28288516
Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndromeQ28302665
Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activationQ28304355
Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neuronsQ28308248
Roles of fragile X mental retardation protein in dopaminergic stimulation-induced synapse-associated protein synthesis and subsequent alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-4-propionate (AMPA) receptor internalizationQ28396707
Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouseQ28506673
Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptorsQ28507196
The translation repressor 4E-BP2 is critical for eIF4F complex formation, synaptic plasticity, and memory in the hippocampusQ28509500
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132Q28510360
Dendritic localization of the RNA-binding protein HuD in hippocampal neurons: association with polysomes and upregulation during contextual learningQ28564874
Cytoplasmic polyadenylation element-like sequences are involved in dendritic targeting of BDNF mRNA in hippocampal neuronsQ28564937
Localization of translational components at the ultramicroscopic level at postsynaptic sites of the rat brainQ28565307
The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expressionQ28567381
A Molecular Mechanism for mRNA Trafficking in Neuronal DendritesQ28568406
Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphologyQ28568504
Huntingtin mediates dendritic transport of β-actin mRNA in rat neuronsQ28568621
Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapsesQ28568714
In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elementsQ28568736
The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granulesQ28568789
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendritesQ28569134
Protein-synthetic machinery beneath postsynaptic sites on CNS neurons: association between polyribosomes and other organelles at the synaptic site.Q30462383
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responsesQ30471587
Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendritesQ30472808
Multiplexed dendritic targeting of alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein RNAs by the A2 pathwayQ30481838
Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neuronsQ30483753
Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR.Q30484083
Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behaviorQ30485596
The Translin/Trax RNA binding complex: clues to function in the nervous systemQ30487690
Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation.Q30490564
Localization of BDNF mRNA with the Huntington's disease protein in rat brainQ30495033
In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neuronsQ30496017
The formation of auditory fear memory requires the synthesis of protein and mRNA in the auditory thalamus.Q30501525
ERK and mTOR signaling couple beta-adrenergic receptors to translation initiation machinery to gate induction of protein synthesis-dependent long-term potentiationQ80628177
BDNF activates mTOR to regulate GluR1 expression required for memory formationQ28569804
Staufen 2 regulates mGluR long-term depression and Map1b mRNA distribution in hippocampal neuronsQ28571617
Role of mitogen-activated protein kinase (MAPK) docking sites on Staufen2 protein in dendritic mRNA transportQ28573232
A role for huntington disease protein in dendritic RNA granulesQ28574690
CPEB-mediated cytoplasmic polyadenylation and the regulation of experience-dependent translation of alpha-CaMKII mRNA at synapsesQ28574713
Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendritesQ28574732
Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNAQ28574872
The transport of Staufen2-containing ribonucleoprotein complexes involves kinesin motor protein and is modulated by mitogen-activated protein kinase pathwayQ28575109
Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapsesQ28576233
Dendritic mRNA targeting of Jacob and N-methyl-d-aspartate-induced nuclear translocation after calpain-mediated proteolysisQ28577700
Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposureQ28577937
Expression of the core exon-junction complex factor eukaryotic initiation factor 4A3 is increased during spatial exploration and striatally-mediated learningQ28578288
Rapid, activity-induced increase in tissue plasminogen activator is mediated by metabotropic glutamate receptor-dependent mRNA translationQ28579381
Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: exclusion from the nucleus and accumulation in dendritic granules and spine headsQ28582163
Molecular characterization of MARTA1, a protein interacting with the dendritic targeting element of MAP2 mRNAsQ28583467
Brain-derived neurotrophic factor enhances the basal rate of protein synthesis by increasing active eukaryotic elongation factor 2 levels and promoting translation elongation in cortical neuronsQ28583609
The brain-specific double-stranded RNA-binding protein Staufen2 is required for dendritic spine morphogenesisQ28583692
Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticityQ28583711
Shank1 mRNA: dendritic transport by kinesin and translational control by the 5'untranslated regionQ28583901
An RNA-interacting protein, SYNCRIP (heterogeneous nuclear ribonuclear protein Q1/NSAP1) is a component of mRNA granule transported with inositol 1,4,5-trisphosphate receptor type 1 mRNA in neuronal dendritesQ28584162
Hzf protein regulates dendritic localization and BDNF-induced translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA.Q28589757
The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2Q28608922
Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosisQ28730723
The RNA-binding protein MARTA2 regulates dendritic targeting of MAP2 mRNAs in rat neuronsQ29144275
The mechanism of eukaryotic translation initiation and principles of its regulationQ29547270
A brain-specific microRNA regulates dendritic spine developmentQ29614753
The mGluR theory of fragile X mental retardationQ29615060
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonistsQ29618120
Kinesin transports RNA: isolation and characterization of an RNA-transporting granuleQ29618417
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regionsQ29620063
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathwayQ29620730
Regulation of cap-dependent translation by eIF4E inhibitory proteinsQ29622831
Demonstration of local protein synthesis within dendrites using a new cell culture system that permits the isolation of living axons and dendrites from their cell bodiesQ30434637
Fragile X: leading the way for targeted treatments in autismQ30435321
Differential subcellular localization of particular mRNAs in hippocampal neurons in cultureQ30453256
Selective dendritic transport of RNA in hippocampal neurons in cultureQ30457336
Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation proteinQ30460772
PKMzeta, LTP maintenance, and the dynamic molecular biology of memory storageQ34590176
Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodiesQ34592681
Local presynaptic activity gates homeostatic changes in presynaptic function driven by dendritic BDNF synthesisQ34613277
Dendritic trafficking of brain-derived neurotrophic factor mRNA: regulation by translin-dependent and -independent mechanismsQ34630493
Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA.Q34660995
The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatumQ34663497
Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2.Q34952541
Safe taste memory consolidation is disrupted by a protein synthesis inhibitor in the nucleus accumbens shell.Q34953805
The nuclear connection in RNA transport and localizationQ35003926
Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signalingQ35047447
Serotonin increases phosphorylation of synaptic 4EBP through TOR, but eukaryotic initiation factor 4E levels do not limit somatic cap-dependent translation in aplysia neuronsQ35131545
Spatial code recognition in neuronal RNA targeting: role of RNA-hnRNP A2 interactions.Q35156972
The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorderQ35159668
Stimulation of glutamate receptor protein synthesis and membrane insertion within isolated neuronal dendritesQ35316948
Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyondQ35614072
Dendritic transport and localization of protein kinase Mzeta mRNA: implications for molecular memory consolidationQ35690019
Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neuronsQ35697823
Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortexQ35721013
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteinsQ35804357
Integrative gene network analysis provides novel regulatory relationships, genetic contributions and susceptible targets in autism spectrum disordersQ35829853
BDNF Val66Met impairs fluoxetine-induced enhancement of adult hippocampus plasticityQ35837743
Identification of a cis-acting element that localizes mRNA to synapsesQ35849542
On the nature and differential distribution of mRNAs in hippocampal neurites: implications for neuronal functioningQ35879302
Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesisQ35891195
Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptinQ35891912
Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR.Q35902026
Presence and phosphorylation of transcription factors in developing dendritesQ35913742
The implications of structured 5' untranslated regions on translation and diseaseQ36013970
On BC1 RNA and the fragile X mental retardation protein.Q36393017
Characterization of a beta-actin mRNA zipcode-binding proteinQ36567715
Selective neuronal degeneration in Huntington's diseaseQ36597920
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesisQ36678825
Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism.Q36741117
Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity.Q42523266
mGluR-dependent long-term depression is associated with increased phosphorylation of S6 and synthesis of elongation factor 1A but remains expressed in S6K-deficient miceQ42525384
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndromeQ42530481
Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT)Q42566713
Two trans-acting rat-brain proteins, MARTA1 and MARTA2, interact specifically with the dendritic targeting element in MAP2 mRNAsQ42798951
NMDA-mediated regulation of DSCAM dendritic local translation is lost in a mouse model of Down's syndrome.Q42868162
Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats.Q42879303
Translational switch for long-term maintenance of synaptic plasticityQ43093197
Reinforcement of early long-term potentiation (early-LTP) in dentate gyrus by stimulation of the basolateral amygdala: heterosynaptic induction mechanisms of late-LTP.Q43594268
Dynamic visualization of local protein synthesis in hippocampal neuronsQ43631820
Induction of long-term depression in cerebellar Purkinje cells requires a rapidly turned over proteinQ43657505
TDP-43: an emerging new player in neurodegenerative diseasesQ43658300
Activation of muscarinic receptors induces protein synthesis-dependent long-lasting depression in the perirhinal cortexQ43698145
A role for the cytoplasmic polyadenylation element in NMDA receptor-regulated mRNA translation in neurons.Q43819947
Actin polymerization and ERK phosphorylation are required for Arc/Arg3.1 mRNA targeting to activated synaptic sites on dendritesQ43922419
Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis.Q44067043
Differential dependence of LTD on glutamate receptors in the auditory cortical synapses of cortical and thalamic inputsQ44238748
Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation stepQ44306459
Modulation of late phases of long-term potentiation in rat dentate gyrus by stimulation of the medial septumQ44430646
Involvement of cholinergic and gabaergic systems in the fragile X knockout miceQ44451055
Bursts of high-frequency stimulation trigger rapid delivery of pre-existing alpha-CaMKII mRNA to synapses: a mechanism in dendritic protein synthesis during long-term potentiation in adult awake ratsQ44489198
Requirement of beta-adrenergic receptor activation and protein synthesis for LTP-reinforcement by novelty in rat dentate gyrusQ44560766
Locus ceruleus activation initiates delayed synaptic potentiation of perforant path input to the dentate gyrus in awake rats: a novel beta-adrenergic- and protein synthesis-dependent mammalian plasticity mechanism.Q44737233
Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptorsQ44760632
Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1.Q44902343
Regulation of dendritic protein synthesis by miniature synaptic events.Q44952134
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.Q44978632
Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.Q44999268
Dynamic interaction between P-bodies and transport ribonucleoprotein particles in dendrites of mature hippocampal neuronsQ45080818
The translational repressor Pumilio regulates presynaptic morphology and controls postsynaptic accumulation of translation factor eIF-4E.Q45148960
Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neuronsQ45303048
The mRNA for elongation factor 1alpha is localized in dendrites and translated in response to treatments that induce long-term depression.Q45932450
Identification of process-localized mRNAs from cultured rodent hippocampal neurons.Q46041476
Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis.Q46267461
Protein synthesis-dependent LTP in isolated dendrites of CA1 pyramidal cellsQ46405126
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.Q46409672
Beta-adrenergic receptor activation facilitates induction of a protein synthesis-dependent late phase of long-term potentiation.Q46412680
Roles of glutamate receptors and the mammalian target of rapamycin (mTOR) signaling pathway in activity-dependent dendritic protein synthesis in hippocampal neuronsQ46451108
Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor traffickingQ46517786
Bidirectional regulation of cytoplasmic polyadenylation element-binding protein phosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1 during hippocampal long-term potentiation.Q46535544
Local protein synthesis mediates a rapid increase in dendritic elongation factor 1A after induction of late long-term potentiation.Q46549246
Induction and maintenance of late-phase long-term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neuronesQ46658286
Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activationQ46815693
FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A.Q46832201
Abnormal striatal GABA transmission in the mouse model for the fragile X syndrome.Q46889350
Arc/Arg3.1 translation is controlled by convergent N-methyl-D-aspartate and Gs-coupled receptor signaling pathwaysQ46915310
Multiple Gq-coupled receptors converge on a common protein synthesis-dependent long-term depression that is affected in fragile X syndrome mental retardation.Q46932828
Postsynaptic decoding of neural activity: eEF2 as a biochemical sensor coupling miniature synaptic transmission to local protein synthesisQ46950342
Regulation of eukaryotic initiation factor 4E by converging signaling pathways during metabotropic glutamate receptor-dependent long-term depression.Q46958338
Differential roles of NR2A and NR2B subtypes in NMDA receptor-dependent protein synthesis in dendritesQ46970923
Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.Q36825291
Distinct role of long 3' UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neuronsQ36856173
Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.Q36857987
Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rateQ36966248
Mechanism and time course of cocaine-induced long-term potentiation in the ventral tegmental areaQ36981194
Macromolecular synthesis, distributed synaptic plasticity, and fear conditioningQ36988799
Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrainQ37013773
Group I metabotropic glutamate receptor-mediated gene expression in striatal neuronsQ37113834
Neuronal activation increases the density of eukaryotic translation initiation factor 4E mRNA clusters in dendrites of cultured hippocampal neuronsQ37337918
Protein translation in synaptic plasticity: mGluR-LTD, Fragile X.Q37467921
Regulation of mRNA transport and translation in axonsQ37543115
Long-term memory for instrumental responses does not undergo protein synthesis-dependent reconsolidation upon retrievalQ37695232
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegenerationQ37733168
TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis?Q37910303
Local translation of mRNAs in neural developmentQ37940412
Deregulated mTOR-mediated translation in intellectual disabilityQ37979606
Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repairQ38002309
Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility.Q38297849
Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers.Q38611833
A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradationQ39293075
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascadeQ39627495
Activity-Dependent Trafficking and Dynamic Localization of Zipcode Binding Protein 1 and β-Actin mRNA in Dendrites and Spines of Hippocampal NeuronsQ39648060
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.Q40347909
Plastic genes are in!Q40628136
CaMKIIalpha 3' untranslated region-directed mRNA translocation in living neurons: visualization by GFP linkage.Q40750607
Arc mRNA docks precisely at the base of individual dendritic spines indicating the existence of a specialized microdomain for synapse-specific mRNA translation.Q41284505
Synapse- and stimulus-specific local translation during long-term neuronal plasticityQ41961783
Phosphorylation of zipcode binding protein 1 is required for brain-derived neurotrophic factor signaling of local beta-actin synthesis and growth cone turning.Q42024647
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branchingQ42096828
Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complexQ42255765
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II.Q42462537
A novel RNA-binding protein in neuronal RNA granules: regulatory machinery for local translation.Q42477506
An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target of rapamycin pathway and deregulation of local dendritic translation in a mouse model of Down's syndrome.Q42490775
Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3' untranslated region of Shank1 mRNA.Q47664805
The Pumilio RNA-binding domain is also a translational regulatorQ47858102
BC1 RNA protein particles in mouse brain contain two y-,h-element-binding proteins, translin and a 37 kDa proteinQ47939545
Identification of a cis-acting dendritic targeting element in MAP2 mRNAs.Q48093967
Rapid synthesis and synaptic insertion of GluR2 for mGluR-LTD in the ventral tegmental areaQ48093999
Muscarinic receptor dependent long-term depression in rat visual cortex is PKC independent but requires ERK1/2 activation and protein synthesisQ48103250
Cholinergic afferents to the locus coeruleus and noradrenergic afferents to the medial septum mediate LTP-reinforcement in the dentate gyrus by stimulation of the amygdalaQ48123786
Cytoplasmic polyadenylation element binding protein 1-mediated mRNA translation in Purkinje neurons is required for cerebellar long-term depression and motor coordinationQ48136862
Synergistic requirements for the induction of dopaminergic D1/D5-receptor-mediated LTP in hippocampal slices of rat CA1 in vitroQ48203935
A critical role for GluN2B-containing NMDA receptors in cortical development and functionQ48205956
Dendritic localization and activity-dependent translation of Engrailed1 transcription factorQ48222236
Dual modes of endoplasmic reticulum-to-Golgi transport in dendrites revealed by live-cell imaging.Q48251594
Dendritically localized transcripts are sorted into distinct ribonucleoprotein particles that display fast directional motility along dendrites of hippocampal neuronsQ48269215
The dendritic translocation of translin protein in the form of BC1 RNA protein particles in developing rat hippocampal neurons in primary cultureQ48313328
Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation controlQ48387996
Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites.Q48403230
Cocaine enhances NMDA receptor-mediated currents in ventral tegmental area cells via dopamine D5 receptor-dependent redistribution of NMDA receptors.Q48445343
Cocaine-but not methamphetamine-associated memory requires de novo protein synthesisQ48448258
Activity bidirectionally regulates AMPA receptor mRNA abundance in dendrites of hippocampal neurons.Q48450791
Disruption of dendritic translation of CaMKIIalpha impairs stabilization of synaptic plasticity and memory consolidationQ48457214
Increased expression of dendritic mRNA following the induction of long-term potentiationQ48462379
Region-directed phototransfection reveals the functional significance of a dendritically synthesized transcription factorQ48524690
Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neuronsQ48567864
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult miceQ48569575
Subcellular localization of specific mRNAs and their protein products in Purkinje cells by combined fluorescence in situ hybridization and immunocytochemistryQ48591014
Behavioral and neurochemical alterations in mice lacking the RNA-binding protein translin.Q48640185
Neuronal RNA granules: a link between RNA localization and stimulation-dependent translationQ48706537
Differential subcellular regulation of NMDAR1 protein and mRNA in dendrites of dentate gyrus granule cells after perforant path transection.Q48765113
Dendritic compartmentation of NMDA receptor mRNA in cultured hippocampal neuronsQ48768439
Translational machinery in dendrites of hippocampal neurons in cultureQ48860517
A protein synthesis-dependent late phase of cerebellar long-term depressionQ48933999
3'UTR-dependent localization of a Purkinje cell messenger RNA in dendritesQ48939594
In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brainQ48961475
Translocation of RNA granules in living neurons.Q48969428
Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus.Q48974772
Identification of a cis-acting element required for dendritic targeting of activity-regulated cytoskeleton-associated protein mRNA.Q50744771
Memory in mice as affected by intracerebral puromycin.Q51285018
Application of a protein synthesis inhibitor into the ventral tegmental area, but not the nucleus accumbens, prevents behavioral sensitization to cocaine.Q51600715
High-resolution fluorescence in situ hybridization to detect mRNAs in neuronal compartments in vitro and in vivo.Q51877406
The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology.Q51935722
Changing subcellular distribution and activity-dependent utilization of a dendritically localized mRNA in developing Purkinje cells.Q52169698
NMDA receptor-mediated control of protein synthesis at developing synapses.Q52170470
RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.Q53299459
Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines.Q55042791
Somatodendritic Localization of Translin, a Component of the Translin/Trax RNA Binding ComplexQ58414665
Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term DepressionQ60141744
Long-term potentiation induced in dendrites separated from rat's CA1 pyramidal somata does not establish a late phaseQ69949944
Protein synthesis-dependent formation of protein kinase Mzeta in long-term potentiationQ71483805
Dendritic and postsynaptic protein synthetic machineryQ77742589
P407language of work or nameEnglishQ1860
P304page(s)106-127
P577publication date2012-12-20
P1433published inNeuroscienceQ15708571
P1476titleDendritic protein synthesis in the normal and diseased brain
P478volume232