review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Dongsheng Cai | |
P2860 | cites work | Endoplasmic reticulum stress plays a central role in development of leptin resistance | Q46178586 |
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. | Q46588693 | ||
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity | Q47314567 | ||
Neuronal PTP1B regulates body weight, adiposity and leptin action. | Q47329751 | ||
Neuroscience. The fat-brain axis enters a new dimension | Q47819287 | ||
Stem cells and neurogenesis in the adult brain | Q48352655 | ||
High-fat diet exacerbates MPTP-induced dopaminergic degeneration in mice | Q48860838 | ||
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration. | Q51966311 | ||
Different early ER-stress responses in the CLN8(mnd) mouse model of neuronal ceroid lipofuscinosis. | Q53288091 | ||
Evidence for constitutive neural cell proliferation in the adult murine hypothalamus. | Q53528240 | ||
Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells. | Q53607069 | ||
Alzheimer's disease | Q55880664 | ||
Mitochondrial diseases | Q83827338 | ||
Obesity and central obesity as risk factors for incident dementia and its subtypes: a systematic review and meta-analysis | Q22242405 | ||
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche | Q24600668 | ||
From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior | Q26828589 | ||
IL-6 mediated degeneration of forebrain GABAergic interneurons and cognitive impairment in aged mice through activation of neuronal NADPH oxidase | Q27349298 | ||
A role for mitochondria in NLRP3 inflammasome activation | Q28131794 | ||
Oxidative stress in neurodegeneration: cause or consequence? | Q28275946 | ||
Disruption of neuronal autophagy by infected microglia results in neurodegeneration | Q28473257 | ||
Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene | Q28505444 | ||
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity | Q28570529 | ||
Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet | Q28572572 | ||
The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight | Q29031436 | ||
Shared principles in NF-kappaB signaling | Q29547234 | ||
Mammalian neural stem cells | Q29547657 | ||
Parkinson's disease | Q29616302 | ||
Inflammasomes in health and disease | Q29616356 | ||
Type 2 diabetes as an inflammatory disease | Q29617184 | ||
Inflammatory mechanisms in obesity | Q29617932 | ||
Central nervous system control of food intake and body weight | Q29619020 | ||
NF-kappaB at the crossroads of life and death | Q29619302 | ||
High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling | Q30496730 | ||
Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis | Q33398039 | ||
High-fat diet induces apoptosis of hypothalamic neurons | Q33425926 | ||
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology | Q33589732 | ||
Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1 | Q33612356 | ||
Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior | Q33664173 | ||
PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice | Q33685586 | ||
Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis. | Q33750727 | ||
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism | Q33778499 | ||
Central administration of interleukin-4 exacerbates hypothalamic inflammation and weight gain during high-fat feeding | Q33994402 | ||
Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis. | Q34059225 | ||
Minireview: Inflammation and obesity pathogenesis: the hypothalamus heats up. | Q34132288 | ||
Obesity and leptin resistance: distinguishing cause from effect | Q34259053 | ||
Obesity-associated hypertension: new insights into mechanisms. | Q34374149 | ||
Anatomy and regulation of the central melanocortin system | Q34414149 | ||
Neurogenesis in the hypothalamus of adult mice: potential role in energy balance | Q34463524 | ||
Circuitry of nuclear factor kappaB signaling | Q34514908 | ||
Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress | Q34583052 | ||
Toll-like receptors modulate adult hippocampal neurogenesis | Q34664161 | ||
Autophagy, inflammation and neurodegenerative disease | Q34686890 | ||
Mechanisms of leptin action and leptin resistance | Q34701125 | ||
De novo neurogenesis in adult hypothalamus as a compensatory mechanism to regulate energy balance | Q34822309 | ||
Inflammatory links between obesity and metabolic disease | Q35015802 | ||
Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation | Q35086140 | ||
Feeding signals and brain circuitry. | Q37624854 | ||
Toll-like receptors: linking inflammation to metabolism | Q37796144 | ||
CNS leptin and insulin action in the control of energy homeostasis | Q37808730 | ||
A role for astrocytes in the central control of metabolism | Q37849519 | ||
Inflammation and lipid signaling in the etiology of insulin resistance | Q38007632 | ||
Metabolic syndrome: a brain disease | Q38036734 | ||
Low-grade hypothalamic inflammation leads to defective thermogenesis, insulin resistance, and impaired insulin secretion | Q39602835 | ||
Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity | Q39734121 | ||
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations | Q40389365 | ||
Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats | Q41064709 | ||
Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB. | Q42058427 | ||
Getting away from glucose: fanning the flames of obesity-induced inflammation | Q42110382 | ||
Activation of the unfolded protein response enhances motor recovery after spinal cord injury | Q42143560 | ||
Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver. | Q42175864 | ||
Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? | Q42514046 | ||
IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes | Q42530961 | ||
Grape seed and skin extract prevents high-fat diet-induced brain lipotoxicity in rat. | Q44388561 | ||
Central administration of an endoplasmic reticulum stress inducer inhibits the anorexigenic effects of leptin and insulin. | Q45960060 | ||
Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway | Q35213340 | ||
Hypothalamic inflammation: a double-edged sword to nutritional diseases | Q35318592 | ||
IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease | Q35370058 | ||
Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice | Q35640540 | ||
Obesity is associated with hypothalamic injury in rodents and humans | Q35640638 | ||
Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance | Q35686688 | ||
One step from prediabetes to diabetes: hypothalamic inflammation? | Q35762665 | ||
Inflammatory cause of metabolic syndrome via brain stress and NF-κB. | Q35857192 | ||
Modeling mitochondrial function in aging neurons | Q35890772 | ||
Hypothalamic sensing of fatty acids | Q36108719 | ||
Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells | Q36137689 | ||
Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis | Q36299540 | ||
The hormonal control of food intake | Q36387304 | ||
Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions | Q36521690 | ||
Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response. | Q36546991 | ||
Attenuation of leptin and insulin signaling by SOCS proteins | Q36607776 | ||
Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo | Q36662772 | ||
How widespread is adult neurogenesis in mammals? | Q36827189 | ||
Insulin sensitivity: modulation by nutrients and inflammation | Q36848937 | ||
Obesity-induced inflammation: a metabolic dialogue in the language of inflammation | Q36944100 | ||
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity | Q36981204 | ||
The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation. | Q36995543 | ||
Anti-inflammatory Agents: Present and Future | Q37118156 | ||
Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain | Q37179554 | ||
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet | Q37190092 | ||
Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence | Q37197121 | ||
Obesity and vulnerability of the CNS. | Q37234576 | ||
Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis | Q37479267 | ||
Central insulin and leptin-mediated autonomic control of glucose homeostasis. | Q37499206 | ||
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity | Q37502701 | ||
NFkappaB-mediated metabolic inflammation in peripheral tissues versus central nervous system | Q37562707 | ||
Insulin resistance and neurodegeneration: roles of obesity, type 2 diabetes mellitus and non-alcoholic steatohepatitis. | Q37602608 | ||
Hypothalamic inflammation and energy homeostasis: resolving the paradox | Q37613162 | ||
The stressed CNS: when glucocorticoids aggravate inflammation. | Q37617620 | ||
P433 | issue | 1 | |
P921 | main subject | overnutrition | Q16956975 |
neuronitis | Q17157137 | ||
P304 | page(s) | 40-47 | |
P577 | publication date | 2012-12-20 | |
P1433 | published in | Trends in Endocrinology and Metabolism | Q15265727 |
P1476 | title | Neuroinflammation and neurodegeneration in overnutrition-induced diseases | |
P478 | volume | 24 |