| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S1470-2045(12)70577-6 |
| P698 | PubMed publication ID | 23276367 |
| P2093 | author name string | Yujie Huang | |
| Jason T Huse | |||
| Jeffrey P Greenfield | |||
| Joon-Hyung Kim | |||
| David Lyden | |||
| P2860 | cites work | Profiling critical cancer gene mutations in clinical tumor samples | Q21562343 |
| Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas | Q24629777 | ||
| IDH1 and IDH2 mutations in gliomas | Q24648948 | ||
| MAPK pathway activation in pilocytic astrocytoma | Q27006028 | ||
| Inhibition of Mutated, Activated BRAF in Metastatic Melanoma | Q27860458 | ||
| Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1 | Q28214401 | ||
| Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas | Q28299301 | ||
| Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma | Q29616862 | ||
| Update on molecular findings, management and outcome in low-grade gliomas | Q30452178 | ||
| Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene | Q33772206 | ||
| BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications | Q33867475 | ||
| Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. | Q33945989 | ||
| Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease | Q33990951 | ||
| Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas | Q34132964 | ||
| Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas | Q34191508 | ||
| Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group | Q34196216 | ||
| Altered telomeres in tumors with ATRX and DAXX mutations | Q34196696 | ||
| Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas | Q34722504 | ||
| Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases | Q48429792 | ||
| Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas | Q48446962 | ||
| Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma | Q48761873 | ||
| Losses of chromosomes 1p and 19q are rare in pediatric oligodendrogliomas | Q48987619 | ||
| MGMT promoter gene methylation in pediatric glioblastoma: analysis using MS-MLPA. | Q49012285 | ||
| BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma. | Q54587637 | ||
| Molecular markers in low-grade gliomas: predictive or prognostic? | Q55463097 | ||
| Cytogenetics in pediatric low-grade astrocytomas. | Q55473718 | ||
| Expression of p53 and prognosis in children with malignant gliomas. | Q55473725 | ||
| Analysis of p53 mutation and expression in pleomorphic xanthoastrocytoma. | Q55474092 | ||
| Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumors. | Q55474205 | ||
| Genomic aberrations in pediatric gliomas and embryonal tumors | Q84475591 | ||
| Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma | Q34787640 | ||
| PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation | Q35092641 | ||
| Molecular profile of oligodendrogliomas in young patients | Q35225293 | ||
| Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma | Q35532490 | ||
| Genomic aberrations in pediatric diffuse intrinsic pontine gliomas | Q35760625 | ||
| Atypical teratoid/rhabdoid tumor evolving from an optic pathway ganglioglioma: case study | Q35800546 | ||
| Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas | Q36010103 | ||
| PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo | Q36453531 | ||
| BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas | Q36532504 | ||
| Pediatric glioblastomas: a histopathological and molecular genetic study | Q37284256 | ||
| Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma | Q37318631 | ||
| Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours | Q37330655 | ||
| Molecular diagnostics of gliomas: state of the art. | Q37780495 | ||
| Gone FISHing: clinical lessons learned in brain tumor molecular diagnostics over the last decade | Q37815544 | ||
| Association between chromosome 1p and 19q loss and outcome in pediatric malignant gliomas: results from the CCG-945 cohort | Q38451493 | ||
| Molecular genetic alterations in pleomorphic xanthoastrocytoma | Q38479213 | ||
| PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation. | Q39425287 | ||
| Atypical teratoid/rhabdoid tumor arising in a ganglioglioma: genetic characterization | Q39443288 | ||
| MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature | Q39646080 | ||
| Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma | Q39788891 | ||
| High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas. | Q39992412 | ||
| MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma | Q40293483 | ||
| Expression of p53, EGFR, pRb and bcl-2 proteins in pediatric glioblastoma multiforme: a study of 54 patients | Q40372031 | ||
| Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo | Q40384702 | ||
| Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma | Q41888346 | ||
| A distinct spectrum of copy number aberrations in pediatric high-grade gliomas | Q41943655 | ||
| Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma | Q42812964 | ||
| Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. | Q42824933 | ||
| MGMT gene promoter methylation in pediatric glioblastomas. | Q43002702 | ||
| Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas | Q43422757 | ||
| Oligodendrogliomas in children | Q43624376 | ||
| Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma | Q44739121 | ||
| Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma. | Q45959776 | ||
| Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. | Q47992753 | ||
| Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomas. | Q48164217 | ||
| Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors. | Q48221611 | ||
| Clinical and molecular characteristics of malignant transformation of low-grade glioma in children | Q48269415 | ||
| Pediatric oligodendrogliomas: a study of molecular alterations on 1p and 19q using fluorescence in situ hybridization. | Q48298546 | ||
| Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets | Q48315065 | ||
| Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas | Q48374829 | ||
| Genetic alterations commonly found in diffusely infiltrating cerebral gliomas are rare or absent in pleomorphic xanthoastrocytomas | Q48425137 | ||
| Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study | Q48428672 | ||
| P433 | issue | 1 | |
| P304 | page(s) | e19-27 | |
| P577 | publication date | 2013-01-01 | |
| P1433 | published in | Lancet Oncology Commission | Q13747613 |
| P1476 | title | Molecular diagnostics in paediatric glial tumours | |
| P478 | volume | 14 |
| Q42290163 | A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. |
| Q48485483 | Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors |
| Q39150377 | Autophagy contributes to ING4-induced glioma cell death |
| Q29248778 | Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility |
| Q36706889 | Early treatment of complex located pediatric low-grade gliomas using iodine-125 brachytherapy alone or in combination with microsurgery |
| Q38203283 | Prognostic and predictive biomarkers in adult and pediatric gliomas: toward personalized treatment |
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