review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Ranjeny Thomas | Q38523203 |
P2093 | author name string | Ranjeny Thomas | |
P2860 | cites work | Oral type II collagen treatment in early rheumatoid arthritis. A double-blind, placebo-controlled, randomized trial | Q70860083 |
Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease | Q24633885 | ||
Essential role for CD103 in the T cell-mediated regulation of experimental colitis | Q24646106 | ||
Rheumatoid synovium is enriched in mature antigen-presenting dendritic cells | Q71614430 | ||
Suppression of collagen induced arthritis by oral administration of type II collagen: changes in immune and arthritic responses mediated by active peripheral suppression | Q71994952 | ||
Effects of oral administration of type II collagen on rheumatoid arthritis | Q72936919 | ||
Allele and antigen-specific treatment of rheumatoid arthritis: a double blind, placebo controlled phase 1 trial | Q73064669 | ||
Differentiated dendritic cells expressing nuclear RelB are predominantly located in rheumatoid synovial tissue perivascular mononuclear cell aggregates | Q73678518 | ||
Nuclear localization of RelB is associated with effective antigen-presenting cell function | Q73900078 | ||
Gastric administration of recombinant 65 kDa heat shock protein delays the severity of type II collagen induced arthritis in mice | Q74477423 | ||
Control of intestinal inflammation by regulatory T cells | Q77291202 | ||
T cell receptor peptide vaccination in rheumatoid arthritis: a placebo-controlled trial using a combination of Vbeta3, Vbeta14, and Vbeta17 peptides | Q77539441 | ||
RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells | Q77769122 | ||
Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis | Q77873010 | ||
Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10 | Q78804319 | ||
Immune modulation and tolerance induction by RelB-silenced dendritic cells through RNA interference | Q80178345 | ||
Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance | Q80358513 | ||
Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB | Q80544759 | ||
Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation | Q80787010 | ||
Skewed T-cell receptor BV14 and BV16 expression and shared CDR3 sequence and common sequence motifs in synovial T cells of rheumatoid arthritis | Q81326728 | ||
IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells | Q81464256 | ||
Cardiovascular death in rheumatoid arthritis: a population-based study | Q81484761 | ||
Development of the anti-citrullinated protein antibody repertoire prior to the onset of rheumatoid arthritis | Q84598175 | ||
Induction of IL-10-producing CD4+CD25+ T cells in animal model of collagen-induced arthritis by oral administration of type II collagen | Q24800770 | ||
Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis | Q24801080 | ||
A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis | Q24805387 | ||
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis | Q28306666 | ||
Expression of relB is required for the development of thymic medulla and dendritic cells | Q28594949 | ||
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism | Q29614266 | ||
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid | Q29615586 | ||
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis | Q29619339 | ||
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid | Q29619479 | ||
The stress protein BiP is overexpressed and is a major B and T cell target in rheumatoid arthritis | Q30664991 | ||
The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin | Q32133798 | ||
Differential expression of Rel/NF-kappaB and octamer factors is a hallmark of the generation and maturation of dendritic cells | Q33884442 | ||
T cell receptor V beta gene bias in rheumatoid arthritis | Q33909663 | ||
Regulation of relB in dendritic cells by means of modulated association of vitamin D receptor and histone deacetylase 3 with the promoter. | Q34085202 | ||
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs | Q34110066 | ||
Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. | Q34193317 | ||
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis | Q34250412 | ||
Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis | Q34290839 | ||
The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner | Q34307377 | ||
Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family | Q34317095 | ||
Immunologic self tolerance maintained by T-cell-mediated control of self-reactive T cells: implications for autoimmunity and tumor immunity | Q34374572 | ||
Control of organ-specific autoimmunity by immunoregulatory CD4(+)CD25(+) T cells | Q34374577 | ||
Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance | Q34448410 | ||
Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial | Q34458468 | ||
Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance | Q34503328 | ||
Epitope spreading in immune-mediated diseases: implications for immunotherapy | Q34575350 | ||
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation | Q34580976 | ||
Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice | Q34705919 | ||
RelB nuclear translocation regulates B cell MHC molecule, CD40 expression, and antigen-presenting cell function. | Q35292814 | ||
Association between baseline radiographic damage and improvement in physical function after treatment of patients with rheumatoid arthritis | Q35554601 | ||
Heat shock proteins (HSP) for immunotherapy of rheumatoid arthritis (RA). | Q35599105 | ||
Restricted heterogeneity of T cell receptor transcripts in rheumatoid synovium | Q35604657 | ||
CDR3 sequence motifs shared by oligoclonal rheumatoid arthritis synovial T cells. Evidence for an antigen-driven response | Q35824763 | ||
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis | Q35894179 | ||
Differential MHC class II-mediated presentation of rheumatoid arthritis autoantigens by human dendritic cells and macrophages | Q47566959 | ||
Neonatal exposure to antigen primes the immune system to develop responses in various lymphoid organs and promotes bystander regulation of diverse T cell specificities. | Q53991776 | ||
Lines of T Lymphocytes Induce or Vaccinate Against Autoimmune Arthritis | Q54503292 | ||
Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells. | Q54656483 | ||
Infectious tolerance. | Q55068093 | ||
Functional differentiation of dendritic cells in rheumatoid arthritis: role of CD86 in the synovium | Q56909013 | ||
Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses | Q57667259 | ||
The HLA–DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide | Q57788778 | ||
Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease | Q58182991 | ||
Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis | Q58234987 | ||
Vitamin A Metabolites Induce Gut-Homing FoxP3+ Regulatory T Cells | Q59336226 | ||
Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses | Q60061990 | ||
Regulation of histone modification and chromatin structure by the p53–PADI4 pathway | Q61207292 | ||
Prevention of postthymectomy autoimmune thyroiditis in mice | Q67484416 | ||
OM-8980 and D-penicillamine in the treatment of rheumatoid arthritis. A 12-month double-blind randomized study | Q68634224 | ||
Constraints on the efficacy of mucosal tolerance in treatment of human and animal arthritic diseases | Q36024861 | ||
Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis | Q36191888 | ||
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice | Q36228938 | ||
T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles | Q36246006 | ||
A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic | Q36350216 | ||
The dichotomous role of IL-2: tolerance versus immunity. | Q36387343 | ||
Cells of the synovium in rheumatoid arthritis. Dendritic cells. | Q36392394 | ||
The insulin A-chain epitope recognized by human T cells is posttranslationally modified | Q36403698 | ||
Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice | Q36537972 | ||
Class II major histocompatibility complex tetramer staining: progress, problems, and prospects | Q37077802 | ||
Vaccines for multiple sclerosis: progress to date | Q37085898 | ||
Expansion of human regulatory T-cells from patients with type 1 diabetes | Q37105331 | ||
High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis? | Q37246396 | ||
Simultaneous detection of many T-cell specificities using combinatorial tetramer staining. | Q37316344 | ||
Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis | Q37356882 | ||
Peptidylarginine deiminase 4 and citrullination in health and disease. | Q37525137 | ||
Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination | Q37837483 | ||
Clinical tolerance in allogeneic hematopoietic stem cell transplantation | Q37864697 | ||
Post-translational modifications of the extracellular matrix are key events in cancer progression: opportunities for biochemical marker development | Q37867110 | ||
Optimising treatment in rheumatoid arthritis: a review of potential biological markers of response | Q37950991 | ||
Economic consequences and potential benefits | Q37964322 | ||
The interplay between endoplasmic reticulum stress and inflammation. | Q37976265 | ||
Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients | Q38462400 | ||
RelB nuclear translocation mediated by C-terminal activator regions of Epstein-Barr virus-encoded latent membrane protein 1 and its effect on antigen-presenting function in B cells | Q39682474 | ||
Preferential recognition of TCR hypervariable regions by human anti-idiotypic T cells induced by T cell vaccination | Q40831654 | ||
Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis. | Q41180997 | ||
Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine and hydroxychloroquine, or a combination of all three medications | Q41930813 | ||
Epitope-specific immunotherapy of rheumatoid arthritis: clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase I | Q41937377 | ||
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination | Q42676934 | ||
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy | Q42971266 | ||
Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis | Q43205831 | ||
Role of NFkappaB in antigen presentation and development of regulatory T cells elucidated by treatment of dendritic cells with the proteasome inhibitor PSI. | Q43658849 | ||
Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis | Q44203278 | ||
Host-reactive CD4+ and CD8+ T cell clones isolated from a human chimera produce IL-5, IL-2, IFN-gamma and granulocyte/macrophage-colony-stimulating factor but not IL-4. | Q44302983 | ||
Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen | Q44466252 | ||
Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule | Q44504170 | ||
T cells signaled by NF-kappa B- dendritic cells are sensitized not anergic to subsequent activation | Q44987457 | ||
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells | Q45878833 | ||
Antigen-specific suppression of inflammatory arthritis using liposomes. | Q46098672 | ||
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells | Q46643896 | ||
P433 | issue | 1 | |
P921 | main subject | cell | Q7868 |
rheumatoid arthritis | Q187255 | ||
autoimmunity | Q192360 | ||
autoantigen | Q4072475 | ||
hemic and immune systems | Q70202933 | ||
dendritic cell | Q506253 | ||
immunotherapy | Q1427096 | ||
P304 | page(s) | 204 | |
P577 | publication date | 2013-02-04 | |
P1433 | published in | Arthritis Research and Therapy | Q15757229 |
P1476 | title | Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis | |
P478 | volume | 15 |
Q47572144 | Adoptive Induced Antigen-Specific Treg Cells Reverse Inflammation in Collagen-Induced Arthritis Mouse Model |
Q39035161 | Adoptive cell transfer in autoimmune hepatitis |
Q38960509 | Altered dendritic cell functions in autoimmune diseases: distinct and overlapping profiles |
Q26852915 | Antigen-based immunotherapy for autoimmune disease: current status |
Q37589108 | Can rheumatoid arthritis be prevented? |
Q57221897 | Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients |
Q36089320 | Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis. |
Q49594014 | Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development |
Q51841138 | Formulation and evaluation of poly(lactic-co-glycolic acid) microspheres loaded with an altered collagen type II peptide for the treatment of rheumatoid arthritis. |
Q92538700 | Human Dendritic Cells Express the Complement Receptor Immunoglobulin Which Regulates T Cell Responses |
Q37661441 | IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease. |
Q47807913 | Model answers: Rational application of murine models in arthritis research |
Q34379951 | Orchestration of transplantation tolerance by regulatory dendritic cell therapy or in-situ targeting of dendritic cells |
Q46547727 | Piperlongumine Suppresses Dendritic Cell Maturation by Reducing Production of Reactive Oxygen Species and Has Therapeutic Potential for Rheumatoid Arthritis |
Q35974666 | Quantitative and qualitative characterization of expanded CD4+ T cell clones in rheumatoid arthritis patients |
Q27686770 | Regulation of B lymphocytes and plasma cells by innate immune mechanisms and stromal cells in rheumatoid arthritis |
Q27025996 | Regulatory dendritic cell therapy: from rodents to clinical application |
Q42322540 | Rheumatology around the world: perspectives from Australia and New Zealand |
Q37156931 | The Effect of Traditional Chinese Formula Danchaiheji on the Differentiation of Regulatory Dendritic Cells |
Q46742418 | Tolerogenic dendritic cells for Type 1 diabetes |
Q47128789 | Translating Mechanism of Regulatory Action of Tolerogenic Dendritic Cells to Monitoring Endpoints in Clinical Trials |
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