Engrailed homeobox transcription factors as potential markers and targets in cancer.

scientific article published on 07 February 2013

Engrailed homeobox transcription factors as potential markers and targets in cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2013.01.054
P698PubMed publication ID23395604
P5875ResearchGate publication ID235441065

P50authorRichard MorganQ54287967
Agnieszka MichaelQ58212792
P2093author name stringHardev Pandha
Sophie E McGrath
P2860cites workThe transcription factor Engrailed-2 guides retinal axonsQ24293543
Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neuronsQ24299087
Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locusQ24535886
Novel HOXA13 mutations and the phenotypic spectrum of hand-foot-genital syndromeQ24538670
Deletions in HOXD13 segregate with an identical, novel foot malformation in two unrelated familiesQ24539303
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cellsQ24564511
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringQ27861072
Amegakaryocytic thrombocytopenia and radio-ulnar synostosis are associated with HOXA11 mutationQ28139165
Homeobox genes and axial patterningQ28181571
Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regionsQ28184648
Agenesis of the mesencephalon and metencephalon with cerebellar hypoplasia: putative mutation in the EN2 gene--report of 2 cases in early infancyQ28216862
Human colorectal carcinogenesis is associated with deregulation of homeobox gene expressionQ28236431
Disrupting the interaction between HOX and PBX causes necrotic and apoptotic cell death in the renal cancer lines CaKi-2 and 769-P.Q39937802
Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma.Q40118504
Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellumQ40357951
EN2 is a candidate oncogene in human breast cancerQ40399564
Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease.Q41465832
Expression of the homeobox Chick-en gene in chick/quail chimeras with inverted mes-metencephalic graftsQ42625960
Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.Q42632235
Intronic single nucleotide polymorphisms of engrailed homeobox 2 modulate the disease vulnerability of autism in a han chinese populationQ46439279
extradenticle raises the DNA binding specificity of homeotic selector gene productsQ46446845
Haplotype analysis of the engrailed-2 gene in young-onset Parkinson's diseaseQ46768641
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Engrailed-2 negatively regulates the onset of perinatal Purkinje cell differentiation.Q47942219
Family-based studies indicate association of Engrailed 2 gene with autism in an Indian populationQ48356030
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Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en.Q48717668
Transcription factor hoxa-5 is taken up by cells in culture and conveyed to their nucleiQ49019926
Involvement of the EN-2 gene in normal and abnormal development of the human arcuate nucleusQ49106726
Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients.Q51655820
Cellular and cis-regulation of En-2 expression in the mandibular arch.Q52124881
Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts.Q52452641
The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.Q54537653
Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorderQ28250796
HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4Q28260217
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemiaQ28273406
Expression of HOXD10 gene in normal endometrium and endometrial adenocarcinomaQ28285408
HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signalingQ28298697
Engrailed-2 (EN2): a tumor specific urinary biomarker for the early diagnosis of prostate cancerQ28306340
A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifenQ28306747
Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2Q28506189
Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobesQ28578739
Engrailed genes are cell-autonomously required to prevent apoptosis in mesencephalic dopaminergic neuronsQ28593451
Association study with two markers of a human homeogene in infantile autismQ30495375
HOXB13-to-IL17BR expression ratio is related with tumor aggressiveness and response to tamoxifen of recurrent breast cancer: a retrospective studyQ33274430
Targeting HOX and PBX transcription factors in ovarian cancerQ33539413
Epigenetic deregulation across chromosome 2q14.2 differentiates normal from prostate cancer and provides a regional panel of novel DNA methylation cancer biomarkers.Q33753677
CpG island hypermethylation in human astrocytomasQ33766932
The expression of an engrailed protein during embryonic shell formation of the tusk-shell, Antalis entalis (Mollusca, Scaphopoda).Q34102003
Rostral optic tectum acquires caudal characteristics following ectopic engrailed expressionQ34396938
Homeobox genes and human genetic disordersQ34566809
Hox genes and vertebrate axial patternQ34995349
CpG island methylation profiling in human salivary gland adenoid cystic carcinomaQ35069629
Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanomaQ35208042
HOX genes in ovarian cancerQ35231971
Developmental transcription factor EN1--a novel biomarker in human salivary gland adenoid cystic carcinomaQ35523364
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assayQ35720707
HOXA9 is required for survival in human MLL-rearranged acute leukemiasQ37129652
DNA hypermethylation accompanied by transcriptional repression in follicular lymphomaQ37334796
The mouse Engrailed genes: a window into autismQ37469452
The Hox genes and their roles in oncogenesis.Q37722452
Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types.Q38366635
Urinary engrailed-2 (EN2) levels predict tumour volume in men undergoing radical prostatectomy for prostate cancer.Q38403484
Targeting the HOX/PBX dimer in breast cancer.Q39262386
Assessing prostate cancer risk: results from the Prostate Cancer Prevention TrialQ39752227
Expression and function of HOXA genes in normal and neoplastic ovarian epithelial cells.Q39873855
HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer).Q39893026
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)549-554
P577publication date2013-02-07
P1433published inFEBS LettersQ1388051
P1476titleEngrailed homeobox transcription factors as potential markers and targets in cancer
P478volume587