Repressive translational control in germ cells

scientific article published on 18 March 2013

Repressive translational control in germ cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/MRD.22161
P698PubMed publication ID23408501
P5875ResearchGate publication ID235621513

P2093author name stringFangfang Lai
Mary Lou King
P2860cites workExtensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeastQ21146425
A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibilityQ24298709
RNA-binding protein Dnd1 inhibits microRNA access to target mRNAQ24304409
Pumilio facilitates miRNA regulation of the E2F3 oncogeneQ24305487
NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cellsQ24317694
Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in non-neuronal cellsQ24530438
Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanismsQ24558492
RNA granulesQ24683783
Modular recognition of RNA by a human pumilio-homology domainQ27639552
Alternate Modes of Cognate RNA Recognition by Human PUMILIO ProteinsQ27667258
The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeastQ27929773
PUF proteins bind Pop2p to regulate messenger RNAsQ27930941
Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiaeQ27937531
Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBFQ27940237
NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongationQ28141291
Translational control by CPEB: a means to the endQ28204377
Germ cells are foreverQ28269858
Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathwaysQ28590991
NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAsQ28594732
Biochemical characterization of Pumilio1 and Pumilio2 in Xenopus oocytesQ30428639
Localization of RNAs to the mitochondrial cloud in Xenopus oocytes through entrapment and association with endoplasmic reticulumQ30833254
DAZL relieves miRNA-mediated repression of germline mRNAs by controlling poly(A) tail length in zebrafishQ30876194
Mechanisms of germ cell specification across the metazoans: epigenesis and preformationQ33194537
Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognitionQ33572943
Repression of zygotic gene expression in the Xenopus germlineQ33684273
Germline development in vertebrates and invertebratesQ33708055
Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclin B1 mRNA.Q33890800
Poly(A)-independent regulation of maternal hunchback translation in the Drosophila embryoQ33944525
The RNA-binding protein XSeb4R: a positive regulator of VegT mRNA stability and translation that is required for germ layer formation in XenopusQ42243244
vasa and nanos expression patterns in a sea anemone and the evolution of bilaterian germ cell specification mechanismsQ42477841
Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAsQ42645915
Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activationQ43192262
Reinvestigation of the role of snapin in neurotransmitter releaseQ44844867
Vegetal pole cells and commitment to form endoderm in Xenopus laevisQ45024148
Translation initiation factors eIF-iso4G and eIF-4B interact with the poly(A)-binding protein and increase its RNA binding activityQ46064189
Control of Dead end localization and activity--implications for the function of the protein in antagonizing miRNA functionQ46068776
The cell cycle program in germ cells of the Drosophila embryoQ46109223
Molecular cloning and transcript analysis of fem-3, a sex-determination gene in Caenorhabditis elegansQ47068933
NANOS-3 and FBF proteins physically interact to control the sperm-oocyte switch in Caenorhabditis elegansQ47069463
Maternal Pumilio acts together with Nanos in germline development in Drosophila embryosQ47070377
The head involution defective gene of Drosophila melanogaster functions in programmed cell deathQ47070937
The Pumilio RNA-binding domain is also a translational regulatorQ47858102
Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding proteinQ48372461
Differential expression of VegT and Antipodean protein isoforms in XenopusQ48565119
Translational control of maternal Cyclin B mRNA by Nanos in the Drosophila germlineQ48798079
Involvement of Xenopus Pumilio in the translational regulation that is specific to cyclin B1 mRNA during oocyte maturationQ48822270
Three-dimensional ultrastructural analysis of RNA distribution within germinal granules of XenopusQ48871346
Ectopic formation of primordial germ cells by transplantation of the germ plasm: direct evidence for germ cell determinant in Xenopus.Q50489493
Germ cell specification in mice.Q51930122
Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline.Q52173308
RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanosQ52445319
Essential role of the posterior morphogen nanos for germline development in Drosophila.Q52547493
Cancer. Germ cell genes and cancer.Q52713516
Regulation of hub mRNA stability and translation by miR430 and the dead end protein promotes preferential expression in zebrafish primordial germ cells.Q54171579
A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish.Q34003437
RNA localization and germ cell determination in XenopusQ34114868
The PUF family of RNA-binding proteins: does evolutionarily conserved structure equal conserved function?Q34273037
A conserved germline multipotency programQ34342503
A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ lineQ34448763
Control of the sperm–oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3′ untranslated regionQ34572336
Identification of germ plasm-associated transcripts by microarray analysis of Xenopus vegetal cortex RNA.Q34726011
Nanos1 functions as a translational repressor in the Xenopus germlineQ34731093
Engineering RNA sequence specificity of Pumilio repeats.Q35025188
Drosophila Brain Tumor is a translational repressorQ35077727
Small noncoding RNAs in the germlineQ35234616
RNA granules in germ cellsQ35578422
Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and brain tumorQ35665678
Sending RNAs into the future: RNA localization and germ cell fateQ35678934
nanos function is essential for development and regeneration of planarian germ cells.Q35749561
Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryosQ35756940
A conserved PUF-Ago-eEF1A complex attenuates translation elongation.Q35801081
Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cellsQ35841025
RNA localization mechanisms in oocytesQ36011458
Cooperativity in RNA-protein interactions: global analysis of RNA binding specificityQ36034599
Nanos suppresses somatic cell fate in Drosophila germ lineQ36671750
Maternal control of pattern formation in Xenopus laevisQ36706392
mRNA poly(A) tail, a 3' enhancer of translational initiationQ36715215
Germ versus soma decisions: lessons from flies and wormsQ36796578
Sexual development of mouse germ cells: Nanos2 promotes the male germ cell fate by suppressing the female pathwayQ37145255
Less is more: specification of the germline by transcriptional repressionQ37321822
New insights into the regulation of RNP granule assembly in oocytesQ37419321
Function of Nanos2 in the male germ cell lineage in miceQ37774954
PUF proteins: repression, activation and mRNA localizationQ37813258
The Ccr4--not complexQ37949473
Translational control in cellular and developmental processesQ38008495
Expression and evolutionary conservation of nanos-related genes in HydraQ38305106
Wheat germ poly(A) binding protein enhances the binding affinity of eukaryotic initiation factor 4F and (iso)4F for cap analogues.Q38553328
A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.Q40424947
Recruitment of Nanos to hunchback mRNA by PumilioQ40445723
P433issue8
P304page(s)665-676
P577publication date2013-03-18
P1433published inMolecular Reproduction and DevelopmentQ6895976
P1476titleRepressive translational control in germ cells
P478volume80

Reverse relations

cites work (P2860)
Q28512503A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis
Q36111014A Transcriptional Lineage of the Early C. elegans Embryo.
Q64968281A new mouse model to study the role of ectopic Nanos3 expression in cancer.
Q48268140A novel role for sox7 in Xenopus early primordial germ cell development: mining the PGC transcriptome.
Q39038811Controlling the Messenger: Regulated Translation of Maternal mRNAs in Xenopus laevis Development
Q38291683Differential Nanos 2 protein stability results in selective germ cell accumulation in the sea urchin
Q27704239Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos
Q91918511Distinct transcriptional regulation of Nanos2 in the germ line and soma by the Wnt and delta/notch pathways
Q37662711Every which way--nanos gene regulation in echinoderms
Q38769331High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration
Q39038829Mechanisms of Vertebrate Germ Cell Determination
Q48110913Nanos genes and their role in development and beyond.
Q37036213Nanos-mediated repression of hid protects larval sensory neurons after a global switch in sensitivity to apoptotic signals.
Q37718833Selective accumulation of germ-line associated gene products in early development of the sea star and distinct differences from germ-line development in the sea urchin
Q24294746Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression
Q26781666The Xenopus Maternal-to-Zygotic Transition from the Perspective of the Germline
Q57283475The balance of poly(U) polymerase activity ensures germline identity, survival and development in
Q28655577The biology of the germ line in echinoderms
Q38893412The diversity of nanos expression in echinoderm embryos supports different mechanisms in germ cell specification
Q88548519The nanos1 gene was duplicated in early Vertebrates and the two paralogs show different gonadal expression profiles in a shark
Q28076597Zebrafish Germ Cell Tumors