ACE2, angiotensin-(1–7), and Mas: the other side of the coin

scientific article published on January 2013

ACE2, angiotensin-(1–7), and Mas: the other side of the coin is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1007595320
P356DOI10.1007/S00424-012-1120-0
P8608Fatcat IDrelease_uadkyhdeuradjl4n2ecj5yaqey
P698PubMed publication ID23463883

P50authorMichael BaderQ37611575
P2860cites workAngiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubuleQ72528938
Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxideQ73086568
The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1Q73765902
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7)Q79349822
An oral formulation of angiotensin-(1-7) produces cardioprotective effects in infarcted and isoproterenol-treated ratsQ83333697
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidaseQ22254730
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9Q24290169
The mas oncogene encodes an angiotensin receptorQ24298473
Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulationQ24311938
The ANG-(1-7)/ACE2/mas axis in the regulation of nephron functionQ24633556
Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor MasQ24680069
Study of angiotensin-(1-7) vasoactive peptide and its beta-cyclodextrin inclusion complexes: complete sequence-specific NMR assignments and structural studiesQ27648672
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidaseQ28115041
Angiotensin-converting enzyme 2 is an essential regulator of heart functionQ28205840
Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissuesQ28583988
Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammationQ28584967
Brain angiotensin-converting enzymes: role of angiotensin-converting enzyme 2 in processing angiotensin II in miceQ33319072
Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertensionQ33639490
Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotectionQ34049167
Angiotensin-converting enzyme 2 attenuates atherosclerotic lesions by targeting vascular cellsQ34115516
Enzymatic processing of angiotensin peptides by human glomerular endothelial cellsQ34213566
The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertensionQ34268946
ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good.Q34784864
Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinasesQ34799585
Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- miceQ34912847
Regulation of alveolar epithelial cell survival by the ACE-2/angiotensin 1-7/Mas axis.Q35217354
Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic miceQ35757097
Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 MiceQ35810634
Angiotensin peptides and lung cancerQ35857462
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injuryQ35916066
Angiotensin II type 2 receptor-stimulated activation of plasma prekallikrein and bradykinin release: role of SHP-1.Q36042466
Cardiovascular actions of angiotensin-(1-7).Q36165955
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heartQ46699250
Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiologyQ46771630
Endothelial dysfunction and elevated blood pressure in MAS gene-deleted miceQ46818973
Mas deficiency in FVB/N mice produces marked changes in lipid and glycemic metabolismQ46891673
Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive ratsQ46985305
Angiotensin-converting enzyme 2 protects from severe acute lung failureQ47768368
Converting enzyme activity and angiotensin metabolism in the dog brainstem.Q48120667
Sustained long term potentiation and anxiety in mice lacking the Mas protooncogeneQ48451358
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR.Q48491814
Angiotensin-(1-7) receptor Mas is an essential modulator of extracellular matrix protein expression in the heart.Q50518097
Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.Q50984005
Sex specific behavioural alterations in Mas-deficient mice.Q51083579
Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury.Q51368117
Genetic deletion of the angiotensin-(1-7) receptor Mas leads to glomerular hyperfiltration and microalbuminuria.Q51785440
Functional rescue of a defective angiotensin II AT1 receptor mutant by the Mas protooncogene.Q51799424
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways.Q51802034
Cardioprotective effects mediated by angiotensin II type 1 receptor blockade and enhancing angiotensin 1-7 in experimental heart failure in angiotensin-converting enzyme 2-null mice.Q53173814
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.Q53463683
Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.Q53553738
Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2.Q54395386
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.Q54705117
ACE2–angiotensin-(1–7)–Mas axis in renal ischaemia/reperfusion injury in ratsQ56774944
Vascular Relaxation, Antihypertensive Effect, and Cardioprotection of a Novel Peptide Agonist of the Mas ReceptorQ56963259
Angiotensin(1-7) Blunts Hypertensive Cardiac Remodeling by a Direct Effect on the HeartQ56963351
Molecular Mechanisms Involved in the Angiotensin-(1-7)/Mas Signaling Pathway in CardiomyocytesQ56963383
Impairment of In Vitro and In Vivo Heart Function in Angiotensin-(1-7) Receptor Mas Knockout MiceQ56963485
Imprinting of the Murine Mas Protooncogene Is Restricted to Its Antisense RNAQ56963615
Angiotensin-(1–7) Attenuates the Development of Heart Failure After Myocardial Infarction in RatsQ61965141
Potentiation of the hypotensive effect of bradykinin by angiotensin-(1–7)-related peptidesQ62124894
The emerging role of angiotensin-converting enzyme-2 in the kidneyQ36733547
High glucose-induced Nox1-derived superoxides downregulate PKC-betaII, which subsequently decreases ACE2 expression and ANG(1-7) formation in rat VSMCsQ37088267
Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axisQ37101896
The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in miceQ37151662
Angiotensin-converting enzyme 2 in the brain: properties and future directionsQ37155907
Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodentsQ37286620
Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer.Q37319058
Trilogy of ACE2: a peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transportersQ37769761
Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin-angiotensin system: a patent reviewQ38003191
Attenuating effect of angiotensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta miceQ38476603
The effect of the thioether-bridged, stabilized Angiotensin-(1-7) analogue cyclic ang-(1-7) on cardiac remodeling and endothelial function in rats with myocardial infarction.Q38896798
Time-resolved quantitative phosphoproteomics: new insights into Angiotensin-(1-7) signaling networks in human endothelial cells.Q39365345
Genetic Ace2 deficiency accentuates vascular inflammation and atherosclerosis in the ApoE knockout mouse.Q39673704
The antithrombotic effect of angiotensin-(1-7) involves mas-mediated NO release from plateletsQ40119975
Discovery and validation of novel peptide agonists for G-protein-coupled receptors.Q40455390
Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.Q40510688
A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11.Q40853474
Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury.Q40867212
The mas oncogene enhances angiotensin-induced [Ca2+]i responses in cells with pre-existing angiotensin II receptorsQ41653426
Cellular carboxypeptidasesQ41745113
An orally active formulation of angiotensin-(1-7) produces an antithrombotic effectQ41830683
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl esterQ42039095
Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7).Q42447014
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells.Q42521222
Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II.Q42821359
Altered cardiovascular reflexes responses in conscious Angiotensin-(1-7) receptor Mas-knockout miceQ42984627
Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.Q43071456
Ablation of angiotensin (1-7) receptor Mas in C57Bl/6 mice causes endothelial dysfunctionQ43090043
Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7).Q43142623
Attenuation of isoproterenol-induced cardiac fibrosis in transgenic rats harboring an angiotensin-(1-7)-producing fusion protein in the heart.Q43201847
Involvement of the Gi/o/cGMP/PKG pathway in the AT2-mediated inhibition of outer cortex proximal tubule Na+-ATPase by Ang-(1-7).Q43247685
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats.Q43547068
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).Q44201695
Expression of an angiotensin-(1-7)-producing fusion protein produces cardioprotective effects in ratsQ44811232
Angiotensin-(1-7) attenuates neointimal formation after stent implantation in the rat.Q45151827
Myocardial infarction increases ACE2 expression in rat and humans.Q45238600
Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in ratsQ46252912
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.Q46352475
Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats.Q46378620
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptorQ46421423
Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effectsQ46604608
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)79-85
P577publication date2013-01-01
P1433published inPfluegers ArchivQ1091689
P1476titleACE2, angiotensin-(1–7), and Mas: the other side of the coin
P478volume465

Reverse relations

cites work (P2860)
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