Statins and autoimmunity

scientific article published on July 2013

Statins and autoimmunity is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1026110325
P356DOI10.1007/S12026-013-8409-8
P698PubMed publication ID23572428

P50authorGisele Zandman-GoddardQ73268900
P2093author name stringSaakshi Khattri
P2860cites workPleiotropic effects of statinsQ24647863
Statin therapy and autoimmune disease: from protein prenylation to immunomodulationQ28236647
Small GTP-binding proteinsQ29547372
Regulation of the mevalonate pathwayQ29547763
The pathogenesis of rheumatoid arthritisQ29614957
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in womenQ29616306
Role of cytokines in rheumatoid arthritisQ29620713
Persistence with Statins and Onset of Rheumatoid Arthritis: A Population-Based Cohort StudyQ33691624
Mortality trends in rheumatoid arthritis: the role of rheumatoid factorQ33709660
Non-lipid-related effects of statinsQ33924588
Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosusQ33974679
Mortality in rheumatoid arthritis: 2008 update.Q34014809
Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammationQ34088380
Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosusQ34098573
Atherosclerosis and systemic lupus erythematosusQ34108806
Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritisQ34283776
Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trialQ34327988
Antiinflammatory and immunomodulatory properties of statinsQ34644504
Isoprenoids as mediators of the biological effects of statinsQ34774535
Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritisQ34776189
Anti-inflammatory and immunomodulating properties of statins. An additional tool for the therapeutic approach of systemic autoimmune diseases?Q34981331
Atorvastatin reduces arterial stiffness in patients with rheumatoid arthritis.Q35553700
High-grade C-reactive protein elevation correlates with accelerated atherogenesis in patients with rheumatoid arthritisQ36183213
Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatinQ36228304
NF-kappaB as a potential therapeutic target in osteoarthritis and rheumatoid arthritisQ36490904
Immunomodulatory effects of statins and autoimmune rheumatic diseases: novel intracellular mechanism involvedQ36628912
Kawasaki Disease With Particular Emphasis on Arterial LesionsQ36939820
A randomized trial of rosuvastatin in the prevention of venous thromboembolismQ37262627
Simvastatin treatment ameliorates autoimmune disease associated with accelerated atherosclerosis in a murine lupus modelQ37362915
The value of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: do they imply new risk factors?Q37674118
Management of refractory anti-phospholipid syndromeQ37874003
Pathogenesis and therapies of immune-mediated myopathiesQ37881005
Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE.Q37883018
Effects of HMG-CoA reductase inhibitors on continuous post-inflammatory vascular remodeling late after Kawasaki diseaseQ39851153
Statins: potentially useful in therapy of systemic sclerosis-related Raynaud's phenomenon and digital ulcersQ39857638
Therapy with statins in patients with refractory rheumatic diseases: a preliminary studyQ40551294
Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis: a pilot studyQ42955705
Statin therapy might be beneficial for patients with ankylosing spondylitisQ42956017
Effect of combining ACE inhibitor and statin in lupus-prone miceQ43093252
Statins for the treatment of antiphospholipid syndrome?Q43275855
Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol loweringQ43516483
Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin siteQ43625666
Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotypeQ43837381
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune diseaseQ43934617
PPAR agonists amplify iNOS expression while inhibiting NF-kappaB: implications for mesangial cell activation by cytokines.Q44111632
A novel anti-inflammatory role for simvastatin in inflammatory arthritisQ44285429
Inhibition of the thrombogenic and inflammatory properties of antiphospholipid antibodies by fluvastatin in an in vivo animal modelQ44652593
Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cellsQ45033718
Atorvastatin inhibits autoreactive B cell activation and delays lupus development in New Zealand black/white F1 miceQ45178632
Global effects of fluvastatin on the prothrombotic status of patients with antiphospholipid syndrome.Q45822025
Effect of fluvastatin on cardiac outcomes in kidney transplant patients with systemic lupus erythematosus: a randomized placebo-controlled studyQ46067922
Effect of pravastatin on outcomes after cardiac transplantation.Q46203599
Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes.Q46614190
Statins as immunomodulators in systemic sclerosisQ46970276
Rate and determinants of progression of atherosclerosis in systemic lupus erythematosusQ46973423
Mortality in early inflammatory polyarthritis: cardiovascular mortality is increased in seropositive patients.Q50701881
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases.Q52574350
Grades of recommendation for antithrombotic agents: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).Q53040204
The role of atorvastatin in regulating the immune response leading to vascular damage in a model of Kawasaki disease.Q54608986
Baseline levels of c-reactive protein and prediction of death from cardiovascular disease in patients with inflammatory polyarthritis : A ten-year followup study of a primary care-based inception cohortQ57804967
Effects of pravastatin in murine collagen-induced arthritisQ79375400
A pravastatin dose-escalation study in systemic lupus erythematosusQ80089099
Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: an 8 weeks controlled trialQ80784895
Ezetimibe and simvastatin reduce inflammation, disease activity, and aortic stiffness and improve endothelial function in rheumatoid arthritisQ80843926
Effect of Atorvastatin on Inflammation and Modification of Vascular Risk Factors in Rheumatoid ArthritisQ82263506
Inhibition of systemic sclerosis dermal fibroblast type I collagen production and gene expression by simvastatinQ83022894
Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: report of a task force at the 13th International Congress on antiphospholipid antibodiesQ83389363
Effects of rosuvastatin on vascular biomarkers and carotid atherosclerosis in lupus: a randomized, double-blind, placebo-controlled trialQ83393976
Bilateral, simultaneous rupture of the quadriceps tendon associated with simvastatinQ84185726
P433issue2-3
P304page(s)348-357
P577publication date2013-07-01
P1433published inImmunologic ResearchQ15754981
P1476titleStatins and autoimmunity
P478volume56

Reverse relations

cites work (P2860)
Q41882404A remarkable hematological and molecular response pattern in a patient with polycythemia vera during combination therapy with simvastatin and alendronate
Q38506851Beyond adjuvants: Antagonizing inflammation to enhance vaccine immunity
Q64262888Cardiac Manifestations of Antiphospholipid Syndrome With Focus on Its Primary Form
Q52772414Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.
Q92616166Detection of Anti-mitochondrial Antibodies Accompanied by Drug-induced Hepatic Injury due to Atorvastatin
Q39293283Effects of Topical Atorvastatin (2 %) on Posthemorrhoidectomy Pain and Wound Healing: A Randomized Double-Blind Placebo-Controlled Clinical Trial
Q38177340Focus on the potential effects of treatments for spondylarthritides on cardiovascular risk
Q59352740Hepatitis B Virus Reactivation in a Patient with Nonalcoholic Steatohepatitis 41 Months after Rituximab-containing Chemotherapy: A Case Report
Q26853576Inflammation in arterial diseases
Q48072382Is statin use associated with new joint-related symptoms, physical function, and quality of life? Results from two population-based cohorts of women
Q33853966KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production
Q64946734Linking CD1-Restricted T Cells With Autoimmunity and Dyslipidemia: Lipid Levels Matter.
Q36330011Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties
Q36867309Neutrophil extracellular traps - the dark side of neutrophils
Q38711126Potential Immunomodulatory Effects of Statins in Inflammatory Bowel Disease
Q44832625Predictors of endothelial dysfunction in patients with rheumatoid arthritis
Q59313325Simvastatin inhibits cytokines in a dose response in patients with rheumatoid arthritis
Q35023243Statin use and markers of immunity in the Doetinchem cohort study
Q87656554Statins Associated With Decreased Risk of New Onset Inflammatory Bowel Disease
Q55402074The Role of Endothelial Progenitors in the Repair of Vascular Damage in Systemic Sclerosis.
Q57020491Topical atorvastatin 1% for prevention of skin toxicity in patients receiving radiation therapy for breast cancer: a randomized, double-blind, placebo-controlled trial
Q43734009Unraveling the soul of autoimmune diseases: pathogenesis, diagnosis and treatment adding dowels to the puzzle

Search more.