scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1003651866 |
P356 | DOI | 10.1007/S00109-013-1050-0 |
P698 | PubMed publication ID | 23661041 |
P50 | author | Sarah L Doyle | Q55948328 |
P2093 | author name string | Matthew Campbell | |
P2860 | cites work | The inflammasomes | Q24304087 |
Complement factor H polymorphism in age-related macular degeneration | Q24553334 | ||
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice | Q24604235 | ||
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 | Q24621930 | ||
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization | Q24631966 | ||
Pyogenic bacterial infections in humans with MyD88 deficiency | Q24653859 | ||
Innate immune recognition | Q27860721 | ||
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors | Q27860900 | ||
A role for mitochondria in NLRP3 inflammasome activation | Q28131794 | ||
Gout-associated uric acid crystals activate the NALP3 inflammasome | Q28131797 | ||
Genetic variation in Toll-like receptors and disease susceptibility | Q28267031 | ||
Influenza virus activates inflammasomes via its intracellular M2 ion channel | Q28279385 | ||
Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 | ||
Inflammation, atherosclerosis, and coronary artery disease | Q29547232 | ||
Origin and physiological roles of inflammation | Q29614298 | ||
Thioredoxin-interacting protein links oxidative stress to inflammasome activation | Q29614471 | ||
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling | Q29615457 | ||
Pathogen recognition by the innate immune system | Q29615592 | ||
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes | Q29615593 | ||
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta | Q29615595 | ||
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals | Q29615704 | ||
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling | Q29616024 | ||
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance | Q29616026 | ||
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis | Q29619852 | ||
Points of control in inflammation | Q29620319 | ||
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components | Q30576000 | ||
Early detection and treatment of neovascular age-related macular degeneration | Q31052084 | ||
Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors | Q33382103 | ||
Forecasting age-related macular degeneration through the year 2050: the potential impact of new treatments | Q33429803 | ||
Toll-like receptor polymorphisms and age-related macular degeneration: replication in three case-control samples | Q33950814 | ||
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP. | Q34246151 | ||
Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. | Q34378842 | ||
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging | Q34556311 | ||
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration | Q34796058 | ||
The biology of IL-12: coordinating innate and adaptive immune responses | Q35209127 | ||
Inflammasome is a central player in the induction of obesity and insulin resistance | Q35216914 | ||
Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration | Q36311846 | ||
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation | Q36332983 | ||
Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process | Q36392611 | ||
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration | Q36530569 | ||
Endogenous TLR ligands and autoimmunity | Q36580095 | ||
Immunosenescence of ageing | Q36698262 | ||
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases | Q36816872 | ||
IL-1, IL-18, and IL-33 families of cytokines | Q37211243 | ||
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome | Q37453447 | ||
Para-inflammation in the aging retina. | Q37533486 | ||
Molecular mechanisms involved in inflammasome activation | Q37588947 | ||
The NLRP3 inflammasome: a sensor for metabolic danger? | Q37675505 | ||
The sterile inflammatory response | Q37716003 | ||
Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration? | Q37767300 | ||
Disease-associated amyloid and misfolded protein aggregates activate the inflammasome | Q37849966 | ||
5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration. | Q37946935 | ||
Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration. | Q37960172 | ||
Biochemical regulation of the inflammasome | Q38017287 | ||
Inflammation and neurodegeneration: the story 'retolled'. | Q38040234 | ||
Inflammation, wound repair, and fibrosis: reassessing the spectrum of tissue injury and resolution | Q38055448 | ||
Toll-like receptor 4 variant D299G is associated with susceptibility to age-related macular degeneration | Q38328036 | ||
Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD). | Q39331392 | ||
Antivascular endothelial growth factor agents for neovascular age-related macular degeneration | Q39519501 | ||
Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands | Q39647439 | ||
Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells | Q39754366 | ||
Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular degeneration | Q41121335 | ||
Toll-like receptor 3 and geographic atrophy in age-related macular degeneration | Q41888443 | ||
Interleukin-1β inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration. | Q41981791 | ||
The privileged immunity of immune privileged organs: the case of the eye. | Q42326687 | ||
Geographic atrophy in age-related macular degeneration and TLR3. | Q42727637 | ||
Isolation of intact lysosomes from human RPE cells and effects of A2-E on the integrity of the lysosomal and other cellular membranes | Q44250118 | ||
Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration. | Q44552145 | ||
Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. The Macular Photocoagulation Study Group | Q46603963 | ||
Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. | Q53529956 | ||
Toll-like Receptor Polymorphisms and Age-Related Macular Degeneration | Q56879650 | ||
Granulomatous reaction to Bruch's membrane in age-related macular degeneration | Q71627644 | ||
Pharmacokinetics of IL-18 binding protein in healthy volunteers and subjects with rheumatoid arthritis or plaque psoriasis | Q80084113 | ||
Complement regulation at necrotic cell lesions is impaired by the age-related macular degeneration-associated factor-H His402 risk variant | Q84964300 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | inflammasome complex | Q412405 |
P304 | page(s) | 1059-1070 | |
P577 | publication date | 2013-05-10 | |
P1433 | published in | Journal of Molecular Medicine | Q6295593 |
P1476 | title | An eye on the future of inflammasomes and drug development in AMD | |
P478 | volume | 91 |
Q35322953 | A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization |
Q91865960 | Adding a Corticosteroid or Switching to Another Anti-VEGF in Insufficiently Responsive Wet Age-Related Macular Degeneration |
Q34588628 | Age-related macular degeneration: insights into inflammatory genes |
Q89637028 | Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration |
Q96351404 | Characterization of Polymeric Syringes Used for Intravitreal Injection |
Q91644810 | Cytokines in Inflammatory Disease |
Q35159598 | Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration. |
Q35610761 | Interleukin-1β Level Is Increased in Vitreous of Patients with Neovascular Age-Related Macular Degeneration (nAMD) and Polypoidal Choroidal Vasculopathy (PCV). |
Q48263177 | Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration. |
Q38596857 | Nanoceria: a Potential Therapeutic for Dry AMD. |
Q38828895 | Risk factors and biomarkers of age-related macular degeneration |
Q28394174 | Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide |
Q38596848 | The NLRP3 Inflammasome and its Role in Age-Related Macular Degeneration |
Q35592392 | Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients |
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