miR deregulation in CLL.

scientific article published on January 2013

miR deregulation in CLL. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/978-1-4614-8051-8_14
P932PMC publication ID4088930
P698PubMed publication ID24014303

P50authorCarlo Maria CroceQ640381
P2093author name stringVeronica Balatti
Lara Rizzotto
Yuri Pekarky
P2860cites workCoupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activationQ24316905
Identification of the TCL1 gene involved in T-cell malignanciesQ24336607
miR-15 and miR-16 induce apoptosis by targeting BCL2Q24536069
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAsQ24537328
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
A microRNA expression signature of human solid tumors defines cancer gene targetsQ24541455
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemiasQ24564008
13q14 deletions in CLL involve cooperating tumor suppressorsQ24618669
MicroRNAs in mouse models of lymphoid malignanciesQ24618980
Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemiaQ24633394
MiR-15a and miR-16-1 cluster functions in human leukemiaQ24647555
Tcl1 enhances Akt kinase activity and mediates its nuclear translocationQ24670140
Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB miceQ24675006
Cancer statistics, 2010Q27860525
The functions of animal microRNAsQ27860621
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responsesQ27861101
The protooncogene TCL1 is an Akt kinase coactivatorQ28138483
Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylationQ28139187
Genomic aberrations and survival in chronic lymphocytic leukemiaQ28141442
B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regionsQ28201835
Comprehensive analysis of a large genomic sequence at the putative B-cell chronic lymphocytic leukaemia (B-CLL) tumour suppresser gene locusQ28203437
Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemiaQ28206302
Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 geneQ28216381
Chronic lymphocytic leukemiaQ28236621
microRNA involvement in human cancerQ28264087
The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemiaQ28269786
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemiaQ28279141
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181Q28279673
A microRNA component of the p53 tumour suppressor networkQ28305330
miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalitiesQ28307338
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathwayQ28615706
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosisQ29547575
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaBQ29614706
An essential role for NF-kappaB in preventing TNF-alpha-induced cell deathQ29614707
The Bcl2 family: regulators of the cellular life-or-death switchQ29614982
Suppression of TNF-alpha-induced apoptosis by NF-kappaBQ29618717
MicroRNA pathways in flies and worms: growth, death, fat, stress, and timingQ29619773
MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemiaQ33333245
In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cellsQ33830733
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrestQ48078984
Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.Q50893928
MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis.Q53341906
APRIL promotes B-1 cell-associated neoplasm.Q53364137
Monoallelic and biallelic deletions of 13q14.3 in chronic lymphocytic leukemia: FISH vs miRNA RT-qPCR detection.Q54318362
Involvement of the bcl-2 gene in human follicular lymphomaQ69870224
Nuclear NF-ATp is a hallmark of unstimulated B cells from B-CLL patientsQ73068687
When and how to treat chronic lymphocytic leukemiaQ73291688
TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survivalQ73925277
Characterization of a novel B-CLL candidate gene--DLEU7--located in the 13q14 tumor suppressor locusQ75224028
Incidence and clinical significance of 6q deletions in B cell chronic lymphocytic leukemiaQ78247896
miR-34a as part of the resistance network in chronic lymphocytic leukemiaQ79674968
The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafishQ80291687
TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative stateQ81600853
17p13/TP53 deletion in B-CLL patients is associated with microRNA-34a downregulationQ82081731
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemiaQ82589392
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemiaQ84484644
MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia.Q33942272
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expressionQ33982310
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expressionQ34068006
Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemiaQ34128395
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocationQ34245495
All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transductionQ34543653
Cell cycle deregulation in B-cell lymphomas.Q34977269
BAFF AND APRIL: a tutorial on B cell survivalQ34994661
miR-181b is a biomarker of disease progression in chronic lymphocytic leukemiaQ35220412
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)Q35787000
MicroRNAs in vertebrate developmentQ36175229
Chronic lymphocytic leukemia: molecular genetics and animal modelsQ36329120
Preferential linkage of bcl-2 to immunoglobulin light chain gene in chronic lymphocytic leukemiaQ36350493
Role of BAFF and APRIL in human B-cell chronic lymphocytic leukaemia.Q36530420
Possible immunoregulatory role for CD5+B cellsQ36589501
Animal models for chronic lymphocytic leukemiaQ36666648
Regulatory mechanisms of microRNAs involvement in cancerQ36897389
Cell proliferation and death: forgotten features of chronic lymphocytic leukemia B cellsQ36914065
The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemiaQ36914074
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemiaQ36948708
Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL.Q37018730
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survivalQ37027816
Molecular diagnostics in chronic lymphocytic leukemia - pathogenetic and clinical implicationsQ37152757
Differential effects of Bcl-2 on T and B cells in transgenic miceQ37321476
Karyotype-specific microRNA signature in chronic lymphocytic leukemiaQ37412319
TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic miceQ37692413
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.Q40102003
Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14.Q40123066
Hematopoietic-specific microRNA expression in human cellsQ40361902
Deletions at 11q identify a subset of patients with typical CLL who show consistent disease progression and reduced survivalQ40877833
Is miR-29 an oncogene or tumor suppressor in CLL?Q42006994
Genetic lesions in chronic lymphocytic leukemia: what's ready for prime time use?Q42938336
CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylationQ43091453
Apoptosis in B-CLL: the relationship between higher ex vivo spontaneous apoptosis before treatment in III-IV Rai stage patients and poor outcome.Q44041908
ZAP-70 expression and prognosis in chronic lymphocytic leukaemiaQ44730335
ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemiaQ46112511
Association between MDM2-SNP309 and age at colorectal cancer diagnosis according to p53 mutation status.Q46944917
An NFAT-dependent enhancer is necessary for anti-IgM-mediated induction of murine CD5 expression in primary splenic B cellsQ47909804
P407language of work or nameEnglishQ1860
P304page(s)309-325
P577publication date2013-01-01
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titlemiR deregulation in CLL.
P478volume792

Reverse relations

cites work (P2860)
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Q38932828microRNA and Chronic Lymphocytic Leukemia