| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/JAC/DKT364 |
| P698 | PubMed publication ID | 24072169 |
| P50 | author | Digby F Warner | Q78493097 |
| Nicolaas C Gey van Pittius | Q42425677 | ||
| Robin M. Warren | Q42425682 | ||
| P2093 | author name string | M McGrath | |
| P D van Helden | |||
| P2860 | cites work | Inhibition of mutation and combating the evolution of antibiotic resistance | Q21146100 |
| Evolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspective | Q24535810 | ||
| Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis | Q24625342 | ||
| Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency | Q24814339 | ||
| Redox homeostasis in mycobacteria: the key to tuberculosis control? | Q27012879 | ||
| Evolution of mutation rates in bacteria | Q28238561 | ||
| Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics | Q28264943 | ||
| Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study | Q28273981 | ||
| Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells | Q28475782 | ||
| Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy | Q28477566 | ||
| Dynamics of antibiotic resistant Mycobacterium tuberculosis during long-term infection and antibiotic treatment | Q28478602 | ||
| Pre-existing isoniazid resistance, but not the genotype of Mycobacterium tuberculosis drives rifampicin resistance codon preference in vitro | Q28478663 | ||
| Essential roles for imuA'- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis | Q28486379 | ||
| Mycobacterium tuberculosis DNA repair in response to subinhibitory concentrations of ciprofloxacin | Q28486678 | ||
| Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C | Q28501841 | ||
| Mechanisms of action of isoniazid | Q29026436 | ||
| Global analysis of the regulon of the transcriptional repressor LexA, a key component of SOS response in Mycobacterium tuberculosis. | Q29346753 | ||
| Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates | Q29618010 | ||
| The spectrum of latent tuberculosis: rethinking the biology and intervention strategies | Q29619404 | ||
| Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis | Q30419570 | ||
| On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient. | Q30519515 | ||
| Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis | Q33318450 | ||
| Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice | Q33338279 | ||
| Key role of Mfd in the development of fluoroquinolone resistance in Campylobacter jejuni | Q33340967 | ||
| Replication dynamics of Mycobacterium tuberculosis in chronically infected mice | Q33557117 | ||
| Defining the requirements for immunological control of mycobacterial infections | Q33724339 | ||
| Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli. | Q33734755 | ||
| Drug resistance evolution of a Mycobacterium tuberculosis strain from a noncompliant patient. | Q42593454 | ||
| Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diarylquinoline ATP synthase inhibitor | Q42910136 | ||
| The transcription elongation factor NusA is required for stress-induced mutagenesis in Escherichia coli | Q42916075 | ||
| Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis. | Q42941702 | ||
| Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis. | Q43234856 | ||
| Bacterial mutagenicity of some tobacco aromatic nitrogen bases and their mixtures | Q43620469 | ||
| Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase | Q43844185 | ||
| Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis. | Q44650604 | ||
| The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds. | Q44944734 | ||
| Empirical treatment of community-acquired pneumonia and the development of fluoroquinolone-resistant tuberculosis | Q45040008 | ||
| Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resistance | Q46221499 | ||
| Effect of subinhibitory concentrations of ciprofloxacin on Mycobacterium fortuitum mutation rates | Q46546957 | ||
| Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair | Q46617407 | ||
| The changing epidemiology of acquired drug-resistant tuberculosis in San Francisco, USA. | Q46911760 | ||
| The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action | Q47215316 | ||
| Lack of mismatch correction facilitates genome evolution in mycobacteria | Q50097192 | ||
| NHEJ protects mycobacteria in stationary phase against the harmful effects of desiccation. | Q50693569 | ||
| Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. | Q51128421 | ||
| A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria. | Q52581205 | ||
| A study on mutational dynamics of simple sequence repeats in relation to mismatch repair system in prokaryotic genomes. | Q53097055 | ||
| Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background. | Q53442441 | ||
| DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence? | Q54120570 | ||
| Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials. | Q54372713 | ||
| Spontaneous Mutations of Bacteria | Q56190181 | ||
| Mutations in mutT genes of Mycobacterium tuberculosis isolates of Beijing genotype | Q57564004 | ||
| Detection and treatment of subclinical tuberculosis | Q57598533 | ||
| The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa | Q33756724 | ||
| Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis | Q33769195 | ||
| Distinct properties of hexameric but functionally conserved Mycobacterium tuberculosis transcription-repair coupling factor | Q33895159 | ||
| Mutation frequencies and antibiotic resistance | Q33945503 | ||
| How antibiotics kill bacteria: from targets to networks | Q33958766 | ||
| Identifying co-targets to fight drug resistance based on a random walk model | Q34132379 | ||
| Genetic risks of antiviral nucleoside analogues--a survey | Q34180549 | ||
| DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis | Q34191816 | ||
| Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection | Q34318215 | ||
| Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis. | Q34334118 | ||
| Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family | Q34502921 | ||
| Mutational spectrum drives the rise of mutator bacteria | Q34550797 | ||
| Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution? | Q34556567 | ||
| Exploring the structure and function of the mycobacterial KatG protein using trans-dominant mutants | Q34721919 | ||
| A practical guide to measuring mutation rates in antibiotic resistance | Q34746116 | ||
| Vibrio cholerae triggers SOS and mutagenesis in response to a wide range of antibiotics: a route towards multiresistance | Q34933315 | ||
| Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity | Q34945420 | ||
| Drug-susceptible Mycobacterium tuberculosis Beijing genotype does not develop mutation-conferred resistance to rifampin at an elevated rate | Q34975227 | ||
| Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection | Q35006626 | ||
| Novel role of mfd: effects on stationary-phase mutagenesis in Bacillus subtilis | Q35130221 | ||
| Mycobacterial survival strategies in the phagosome: defence against host stresses | Q35205535 | ||
| Nucleoside reverse transcriptase inhibitors and HIV mutagenesis | Q35209886 | ||
| ClpR protein-like regulator specifically recognizes RecA protein-independent promoter motif and broadly regulates expression of DNA damage-inducible genes in mycobacteria | Q35213214 | ||
| Induction of the SOS response in Escherichia coli by azidothymidine and dideoxynucleosides | Q35263031 | ||
| WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication | Q35394336 | ||
| Multidrug-resistant tuberculosis not due to noncompliance but to between-patient pharmacokinetic variability | Q35532853 | ||
| Rates of drug resistance and risk factor analysis in civilian and prison patients with tuberculosis in Samara Region, Russia | Q35537453 | ||
| Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation. | Q35584999 | ||
| An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response | Q35629407 | ||
| Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions | Q35666457 | ||
| In vitro analysis of rates and spectra of mutations in a polymorphic region of the Rv0746 PE_PGRS gene of Mycobacterium tuberculosis | Q35759371 | ||
| Error-prone replication for better or worse | Q35785643 | ||
| The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs. | Q35842269 | ||
| Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB. | Q35844623 | ||
| Effect of mutation and genetic background on drug resistance in Mycobacterium tuberculosis | Q36018737 | ||
| Modeling the dynamic relationship between HIV and the risk of drug-resistant tuberculosis | Q36070976 | ||
| DNA replication fidelity in Escherichia coli: a multi-DNA polymerase affair. | Q36080876 | ||
| Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. | Q36132703 | ||
| Consequences of noncompliance for therapy efficacy and emergence of resistance in murine tuberculosis caused by the Beijing genotype of Mycobacterium tuberculosis | Q36172471 | ||
| Mycobacterium tuberculosis Beijing strains favor transmission but not drug resistance in China | Q36303080 | ||
| Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients | Q36368678 | ||
| RNA polymerase encounters with DNA damage: transcription-coupled repair or transcriptional mutagenesis? | Q36389652 | ||
| Too many mutants with multiple mutations | Q36491712 | ||
| β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity | Q36737307 | ||
| Stress-induced mutagenesis in bacteria. | Q36961683 | ||
| Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase | Q37051357 | ||
| Cell death from antibiotics without the involvement of reactive oxygen species | Q37065875 | ||
| Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness | Q37120860 | ||
| Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis | Q37184072 | ||
| Host-directed drug targeting of factors hijacked by pathogens | Q37224146 | ||
| Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosis | Q37349855 | ||
| Transcriptional responses of Mycobacterium tuberculosis to lung surfactant | Q37357690 | ||
| A replication clock for Mycobacterium tuberculosis | Q37426997 | ||
| DNA repair in Mycobacterium tuberculosis revisited | Q37455209 | ||
| Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis | Q37637992 | ||
| DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection | Q37762580 | ||
| Cellular mechanisms that control mistranslation | Q37809740 | ||
| Base excision and nucleotide excision repair pathways in mycobacteria | Q37901961 | ||
| Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH. | Q38435339 | ||
| Resistant mutants of Mycobacterium tuberculosis selected in vitro do not reflect the in vivo mechanism of isoniazid resistance | Q38905383 | ||
| Specific mutations in the Mycobacterium tuberculosis rpoB gene are associated with increased dnaE2 expression | Q38905392 | ||
| A distinct physiological role of MutY in mutation prevention in mycobacteria. | Q39795549 | ||
| Biochemical properties of MutT2 proteins from Mycobacterium tuberculosis and M. smegmatis and their contrasting antimutator roles in Escherichia coli | Q39797576 | ||
| Detrimental effects of hypoxia-specific expression of uracil DNA glycosylase (Ung) in Mycobacterium smegmatis. | Q41430697 | ||
| Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis | Q41818442 | ||
| Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks | Q42078607 | ||
| Induction of mycobacterial resistance to quinolone class antimicrobials | Q42210567 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Mycobacterium tuberculosis | Q130971 |
| drug resistance | Q12147416 | ||
| P304 | page(s) | 292-302 | |
| P577 | publication date | 2013-09-26 | |
| P1433 | published in | Journal of Antimicrobial Chemotherapy | Q6294770 |
| P1476 | title | Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis | |
| P478 | volume | 69 |
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| Q50107946 | DNA Replication Fidelity in the Mycobacterium tuberculosis Complex |
| Q39210590 | DNA Replication in Mycobacterium tuberculosis |
| Q47578348 | Deregulation of Genes Associated with Alternate Drug Resistance Mechanisms in Mycobacterium tuberculosis. |
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| Q42673180 | Diversity and evolution of drug resistance mechanisms in Mycobacterium tuberculosis |
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| Q27016579 | Evolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapy |
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