| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1002803562 |
| P356 | DOI | 10.1007/S12035-013-8554-Z |
| P698 | PubMed publication ID | 24085563 |
| P5875 | ResearchGate publication ID | 257301773 |
| P50 | author | George Anderson | Q70640445 |
| P2093 | author name string | Michael Maes | |
| P2860 | cites work | Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice | Q21198922 |
| PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease | Q24294809 | ||
| PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease | Q24597726 | ||
| N-acetylserotonin activates TrkB receptor in a circadian rhythm | Q24623798 | ||
| Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease | Q27334826 | ||
| The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS | Q28244138 | ||
| Heme: a regulator of rat hepatic tryptophan 2,3-dioxygenase? | Q28377370 | ||
| Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis | Q28510836 | ||
| Effect of TNF-alpha on the melatonin synthetic pathway in the rat pineal gland: basis for a 'feedback' of the immune response on circadian timing | Q28565774 | ||
| Nicotine inhibits Fc epsilon RI-induced cysteinyl leukotrienes and cytokine production without affecting mast cell degranulation through alpha 7/alpha 9/alpha 10-nicotinic receptors | Q28568538 | ||
| Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure | Q28577899 | ||
| The pannexin 1 channel activates the inflammasome in neurons and astrocytes | Q28583666 | ||
| BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets | Q28591152 | ||
| Acidic fibroblast growth factor delivered intranasally induces neurogenesis and angiogenesis in rats after ischemic stroke | Q49049783 | ||
| Aging-associated alteration of telomere length and subtelomeric status in female patients with Parkinson's disease. | Q50767570 | ||
| Telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging. | Q50942049 | ||
| Neuroimmune interactions in patients with inflammatory bowel diseases: disease activity and clinical behavior based on Substance P serum levels. | Q53648903 | ||
| Mitochondrial defect and PGC-1α dysfunction in parkin-associated familial Parkinson's disease. | Q54393752 | ||
| IgM-mediated autoimmune responses directed against multiple neoepitopes in depression: New pathways that underpin the inflammatory and neuroprogressive pathophysiology | Q56767086 | ||
| Plasma soluble interleukin-2-receptor in depression: relationships to plasma neopterin and serum IL-2 concentrations and HPA-axis activity | Q56767500 | ||
| Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation | Q79753759 | ||
| Promoter methylation analysis of seven clock genes in Parkinson's disease | Q83114471 | ||
| Interleukin-18 promoter polymorphisms and risk of Parkinson's disease in a Han Chinese population | Q83222229 | ||
| Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors | Q83629988 | ||
| Study of telomere length and different markers of oxidative stress in patients with Parkinson's disease | Q83709786 | ||
| Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases | Q84052928 | ||
| Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease | Q84185160 | ||
| Lack of association between IL-1β, TNF-α, and IL-10 gene polymorphisms and sporadic Parkinson’s disease in an Italian cohort | Q85110030 | ||
| Protective effect of l-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: Implications of modulating kynurenate as a protective strategy | Q85174010 | ||
| Increased neopterin production and tryptophan degradation in advanced Parkinson's disease | Q44035901 | ||
| Association of plasma interleukin-18 levels with emotion regulation and μ-opioid neurotransmitter function in major depression and healthy volunteers | Q44348647 | ||
| Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration? | Q44478521 | ||
| Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells | Q44751656 | ||
| Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes | Q44925904 | ||
| Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a manner of autocrine action | Q45208064 | ||
| Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo | Q45288791 | ||
| Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia. | Q45923132 | ||
| beta-adrenergic enhancement of brain kynurenic acid production mediated via cAMP-related protein kinase A signaling. | Q46014111 | ||
| Colonic inflammation in Parkinson's disease. | Q46015750 | ||
| Cystine glutamate exchanger upregulation by retinoic acid induces neuroprotection in neural stem cells | Q46448986 | ||
| Circadian dysfunction in a mouse model of Parkinson's disease | Q46527998 | ||
| Kynurenine metabolism in plasma and in red blood cells in Parkinson's disease | Q46649609 | ||
| Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats | Q46742399 | ||
| The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation | Q46862597 | ||
| Preferential vulnerability of mesencephalic dopamine neurons to glutamate transporter dysfunction. | Q46879824 | ||
| Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin. | Q46921650 | ||
| Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. | Q46938193 | ||
| Neuropeptides activate human mast cell degranulation and chemokine production | Q46961068 | ||
| Pineal melatonin and the innate immune response: the TNF-alpha increase after cesarean section suppresses nocturnal melatonin production | Q46970993 | ||
| Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain | Q48179563 | ||
| 4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites | Q48251144 | ||
| Acidic and basic fibroblast growth factor mRNAs are increased in striatum following MPTP-induced dopamine neurofiber lesion: assay by quantitative PCR | Q48281276 | ||
| Association of Tef polymorphism with depression in Parkinson disease. | Q48302805 | ||
| Alteration in glutathione content and associated enzyme activities in the synaptic terminals but not in the non-synaptic mitochondria from the frontal cortex of Parkinson's disease brains | Q48334569 | ||
| Kynurenines impair energy metabolism in rat cerebral cortex | Q48345142 | ||
| Expression of clock genes Per1 and Bmal1 in total leukocytes in health and Parkinson's disease | Q48382156 | ||
| In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain | Q48426476 | ||
| Effect of 6-hydroxydopamine treatment on kynurenine aminotransferase-I (KAT-I) immunoreactivity of neurons and glial cells in the rat substantia nigra. | Q48491650 | ||
| Diagnostic classifications in depression and somatization should include biomarkers, such as disorders in the tryptophan catabolite (TRYCAT) pathway | Q48723299 | ||
| The MPTP neurotoxic lesion model of Parkinson's disease activates the apolipoprotein E cascade in the mouse brain | Q48789115 | ||
| Psychiatric symptoms screening in the early stages of Parkinson's disease | Q48846072 | ||
| Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: implications for Parkinson's disease | Q48860624 | ||
| Evidence for a key role of the peripheral kynurenine pathway in the modulation of anxiety- and depression-like behaviours in mice: focus on individual differences | Q48945468 | ||
| cAMP-dependent signaling as a core component of the mammalian circadian pacemaker | Q42541521 | ||
| Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect | Q42730712 | ||
| Kynurenic acid inhibits the release of the neurotrophic fibroblast growth factor (FGF)-1 and enhances proliferation of glia cells, in vitro | Q42806464 | ||
| Endogenous dopamine regulates the rhythm of expression of the clock protein PER2 in the rat dorsal striatum via daily activation of D2 dopamine receptors. | Q42852553 | ||
| Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy. | Q42904554 | ||
| BIdirectional Regulation of Neurogenesis by Neuronal Nitric Oxide Synthase Derived from Neurons and Neural Stem Cells | Q42906028 | ||
| Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression | Q43162900 | ||
| Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate | Q43600956 | ||
| Stimulation of non-alpha7 nicotinic receptors partially protects dopaminergic neurons from 1-methyl-4-phenylpyridinium-induced toxicity in culture | Q43860478 | ||
| Interleukin-12 and interleukin-18 induce indoleamine 2,3-dioxygenase (IDO) activity in human osteosarcoma cell lines independently from interferon-gamma | Q43996247 | ||
| Neuroregeneration in neurodegenerative disorders | Q31020342 | ||
| Neurokinin-1 and neurokinin-3 receptors in primate substantia nigra | Q33264988 | ||
| Circadian modulation of gene expression, but not glutamate uptake, in mouse and rat cortical astrocytes | Q33510680 | ||
| No evidence of substantia nigra telomere shortening in Parkinson's disease | Q33665078 | ||
| Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease | Q33906098 | ||
| Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis | Q33958241 | ||
| Treatment with a substance P receptor antagonist is neuroprotective in the intrastriatal 6-hydroxydopamine model of early Parkinson's disease | Q34224832 | ||
| Biological underpinnings of the commonalities in depression, somatization, and Chronic Fatigue Syndrome. | Q34263425 | ||
| Nicotine as a potential neuroprotective agent for Parkinson's disease | Q34281003 | ||
| Inhibition of human MAO-A and MAO-B by a compound isolated from flue-cured tobacco leaves and its neuroprotective properties in the MPTP mouse model of neurodegeneration | Q34307652 | ||
| Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway | Q34320082 | ||
| Dopamine depletion impairs precursor cell proliferation in Parkinson disease. | Q34326801 | ||
| Expression of indoleamine 2,3-dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons | Q34351574 | ||
| Age-associated changes in oxidative stress and NAD+ metabolism in human tissue. | Q34359729 | ||
| FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels | Q34450040 | ||
| Brain molecular aging, promotion of neurological disease and modulation by Sirtuin5 longevity gene polymorphism | Q34458952 | ||
| CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease | Q34471903 | ||
| Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf | Q34473733 | ||
| NF-κB drives the synthesis of melatonin in RAW 264.7 macrophages by inducing the transcription of the arylalkylamine-N-acetyltransferase (AA-NAT) gene | Q34532746 | ||
| Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells | Q35005980 | ||
| 4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification. | Q35041432 | ||
| Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling | Q35078537 | ||
| Genetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosis | Q35604592 | ||
| Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury | Q35672546 | ||
| SIRT1 protects against α-synuclein aggregation by activating molecular chaperones | Q35686386 | ||
| Localisation of novel forms of glutamate transporters and the cystine-glutamate antiporter in the choroid plexus: Implications for CSF glutamate homeostasis. | Q35822260 | ||
| Acidic fibroblast growth factor (FGF) potentiates glial-mediated neurotoxicity by activating FGFR2 IIIb protein | Q35842086 | ||
| Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat | Q35978861 | ||
| Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response | Q36098825 | ||
| Role of inflammation in gastrointestinal tract in aetiology and pathogenesis of idiopathic parkinsonism | Q36113403 | ||
| Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease | Q36167615 | ||
| α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1. | Q36234694 | ||
| Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein | Q36294810 | ||
| The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand | Q36459060 | ||
| Parkinson's disease risk from ambient exposure to pesticides | Q36815122 | ||
| Circadian and sleep disorders in Parkinson's disease | Q36882599 | ||
| Serotonin of mast cell origin contributes to hippocampal function | Q37041302 | ||
| Glutathione and Parkinson's disease: is this the elephant in the room? | Q37133529 | ||
| Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. | Q37152191 | ||
| Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc | Q37228297 | ||
| Effect of dioxins on regulation of tyrosine hydroxylase gene expression by aryl hydrocarbon receptor: a neurotoxicology study | Q37236889 | ||
| Role of cAMP in mediating AHR signaling | Q37326966 | ||
| Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease | Q37671552 | ||
| Depression's multiple comorbidities explained by (neuro)inflammatory and oxidative & nitrosative stress pathways. | Q37853349 | ||
| Epidemiology and etiology of Parkinson's disease: a review of the evidence | Q37882546 | ||
| The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications | Q38004705 | ||
| Adult neurogenesis in Parkinson's disease | Q38024276 | ||
| Dysfunction of the locus coeruleus-norepinephrine system and related circuitry in Parkinson's disease-related dementia | Q38051969 | ||
| The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides. | Q38072236 | ||
| The circadian clock circuitry and the AHR signaling pathway in physiology and pathology. | Q38084405 | ||
| TRYCAT pathways link peripheral inflammation, nicotine, somatization and depression in the etiology and course of Parkinson's disease. | Q38120786 | ||
| Oxidative/nitrosative stress and immuno-inflammatory pathways in depression: treatment implications. | Q38158129 | ||
| Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein. | Q38323425 | ||
| Interference of alpha-synuclein with cAMP/PKA-dependent CREB signaling for tyrosine hydroxylase gene expression in SK-N-BE(2)C cells | Q38473449 | ||
| Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons. | Q38728529 | ||
| Induction of KLF4 contributes to the neurotoxicity of MPP + in M17 cells: a new implication in Parkinson's disease | Q39201271 | ||
| A disruption mechanism of the molecular clock in a MPTP mouse model of Parkinson's disease. | Q39215656 | ||
| Potential of a γ-glutamyl-transpeptidase-stable glutathione analogue against amyloid-β toxicity | Q39302911 | ||
| Protective effects of nicotine against aminochrome-induced toxicity in substantia nigra derived cells: implications for Parkinson's disease | Q39360051 | ||
| Aryl hydrocarbon receptor ligand effects in RBL2H3 cells | Q39370105 | ||
| Apolipoprotein E influences melatonin biosynthesis by regulating NAT and MAOA expression in C6 cells | Q39416376 | ||
| Interleukin-1β: a new regulator of the kynurenine pathway affecting human hippocampal neurogenesis | Q39445647 | ||
| Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease | Q39460847 | ||
| Neuroprotective effects of neurokinin receptor one in dopaminergic neurons are mediated through Akt/PKB cell signaling pathway | Q39476426 | ||
| Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression | Q39981261 | ||
| Cultured rat cortical astrocytes synthesize melatonin: absence of a diurnal rhythm. | Q40084744 | ||
| Modulation of D1-like dopamine receptor function by aldehydic products of lipid peroxidation | Q40663110 | ||
| Products of oxidative stress inhibit aldehyde oxidation and reduction pathways in dopamine catabolism yielding elevated levels of a reactive intermediate | Q41489303 | ||
| Norepinephrine: the next therapeutics frontier for Parkinson's disease | Q41975512 | ||
| Up-regulation of gamma-glutamyl transpeptidase activity following glutathione depletion has a compensatory rather than an inhibitory effect on mitochondrial complex I activity: implications for Parkinson's disease | Q41993703 | ||
| Neurogenesis directed by Sirt1. | Q42058043 | ||
| The cystine/glutamate antiporter regulates indoleamine 2,3-dioxygenase protein levels and enzymatic activity in human dendritic cells. | Q42408190 | ||
| Striatonigral GABA, dynorphin, substance P and neurokinin A modulation of nigrostriatal dopamine release: evidence for direct regulatory mechanisms | Q42466303 | ||
| Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system | Q42502064 | ||
| P433 | issue | 2 | |
| P921 | main subject | neurodegeneration | Q1755122 |
| Parkinson's disease | Q11085 | ||
| mitochondrion | Q39572 | ||
| P304 | page(s) | 771-783 | |
| P577 | publication date | 2013-10-02 | |
| P1433 | published in | Molecular Neurobiology | Q15716645 |
| P1476 | title | Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins | |
| P478 | volume | 49 |
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