Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions

scientific article published on 25 October 2013

Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/PHP.12197
P698PubMed publication ID24354557
P5875ResearchGate publication ID259392706

P50authorAndrea Christa KneuttingerQ84866897
Thomas CarellQ109816
Markus MüllerQ1334898
P2093author name stringKorbinian Heil
Gengo Kashiwazaki
Stefan Prill
P2860cites workWhat makes the difference between a cryptochrome and DNA photolyase? A spectroelectrochemical comparison of the flavin redox transitions.Q50454969
Intraprotein radical transfer during photoactivation of DNA photolyase.Q50511512
Reaction mechanism of (6-4) photolyase.Q52560710
Repair of the (6-4) photoproduct by DNA photolyase requires two photons.Q53105776
RNA is more UV resistant than DNA: the formation of UV-induced DNA lesions is strongly sequence and conformation dependent.Q53883286
Dark repair of DNA containing "spore photoproduct" in Bacillus subtilis.Q54332811
Accelerated deamination of cytosine residues in UV-induced cyclobutane pyrimidine dimers leads to CC-->TT transitions.Q54583234
Deamination of cytosine-containing pyrimidine photodimers in UV-irradiated DNA. Significance for UV light mutagenesis.Q54601733
The radical SAM enzyme spore photoproduct lyase employs a tyrosyl radical for DNA repairQ57376728
Mechanism of UV-Induced Formation of Dewar Lesions in DNAQ57376745
Synthesis and properties of DNA containing a spore photoproduct analogQ57376789
Single Amino Acid Substitution Reveals Latent Photolyase Activity inArabidopsiscry1Q57637148
Thymine dimerization in DNA is an ultrafast photoreactionQ24642044
A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activityQ24680064
The archaeal cofactor F 0 is a light-harvesting antenna chromophore in eukaryotesQ27646389
Crystal structure and mechanism of a DNA (6-4) photolyaseQ27652687
Recognition and repair of UV lesions in loop structures of duplex DNA by DASH-type cryptochromeQ27653123
Crystal structure of the T(6-4)C lesion in complex with a (6-4) DNA photolyase and repair of UV-induced (6-4) and Dewar photolesionsQ27657256
DNA (6-4) photolyases reduce Dewar isomers for isomerization into (6-4) lesionsQ27659908
Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzymeQ27670632
Crystal structures and repair studies reveal the identity and the base-pairing properties of the UV-induced spore photoproduct DNA lesionQ27670948
Crystal structures of an archaeal class II DNA photolyase and its complex with UV-damaged duplex DNAQ27673034
CryB from Rhodobacter sphaeroides: a unique class of cryptochromes with new cofactorsQ27676947
Crystal structure of a prokaryotic (6-4) photolyase with an Fe-S cluster and a 6,7-dimethyl-8-ribityllumazine antenna chromophoreQ27677403
A Radical Transfer Pathway in Spore Photoproduct LyaseQ27677488
Crystal Structure of DNA Photolyase from Escherichia coliQ27729755
Atomic model of a pyrimidine dimer excision repair enzyme complexed with a DNA substrate: structural basis for damaged DNA recognitionQ27732192
Crystal structure of DNA photolyase from Anacystis nidulansQ27746979
Structure and function of DNA photolyase and cryptochrome blue-light photoreceptorsQ28178089
Light-driven DNA repair by photolyasesQ28240124
Toxic effects of ultraviolet radiation on the skinQ28250343
Characterization of an active spore photoproduct lyase, a DNA repair enzyme in the radical S-adenosylmethionine superfamilyQ28251030
The subunit structure and catalytic mechanism of the Bacillus subtilis DNA repair enzyme spore photoproduct lyaseQ28488999
A photolyase-like protein from Agrobacterium tumefaciens with an iron-sulfur clusterQ28492357
Kinetics of cyclobutane thymine dimer splitting by DNA photolyase directly monitored in the UVQ29542108
Stereochemistry of Electrocyclic ReactionsQ30051770
Intraprotein electron transfer between tyrosine and tryptophan in DNA photolyase from Anacystis nidulansQ30631585
Chemical and transient spectroscopic evidence for C2-C3 cleavage of 2,3-diaryloxetane radical cationsQ30890228
Nucleotide excision repair: new tricks with old bricksQ33353971
Combined NMR and DFT studies for the absolute configuration elucidation of the spore photoproduct, a UV-induced DNA lesionQ33384707
DNA excited-state dynamics: from single bases to the double helixQ33384715
Functional diversity of the DNA photolyase/blue light receptor familyQ33697167
A new photoproduct of 5-methylcytosine and adenine characterized by high-performance liquid chromatography and mass spectrometryQ33729312
Emerging themes in radical SAM chemistryQ33851840
DNA protection by stress-induced biocrystallizationQ33867772
Mechanistic studies on the repair of a novel DNA photolesion: the spore photoproductQ33903064
Ringlike structure of the Deinococcus radiodurans genome: a key to radioresistance?Q33963655
Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNAQ34062137
UV-induced DNA damage and repair: a reviewQ34186547
Light-driven enzymatic catalysis of DNA repair: a review of recent biophysical studies on photolyaseQ34396116
Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyaseQ34479773
The spore photoproduct lyase repairs the 5S- and not the 5R-configured spore photoproduct DNA lesionQ34496794
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation.Q34563627
Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates.Q35091451
Elucidation of Spore‐Photoproduct Formation by Isotope LabelingQ35094051
Inter-strand photoproducts are produced in high yield within A-DNA exposed to UVC radiationQ35107927
Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyaseQ35202819
Structural aspects of DNA repair: the role of restricted diffusionQ35583484
A QM/MM investigation of thymine dimer radical anion splitting catalyzed by DNA photolyaseQ46193748
Model compounds for (6-4) photolyases: a comparative flavin induced cleavage study of oxetanes and thietanesQ46486490
Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations.Q46541033
Essential cysteine residues in Bacillus subtilis spore photoproduct lyase identified by alanine scanning mutagenesisQ46703813
The DNA damage spectrum produced by simulated sunlightQ47590963
Ultrafast excited-state dynamics in nucleic acidsQ35744404
DNA charge transport as a first step in coordinating the detection of lesions by repair proteinsQ35751064
Adenine photodimerization in deoxyadenylate sequences: elucidation of the mechanism through structural studies of a major d(ApA) photoproductQ35765418
Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyaseQ35965630
Ultraviolet radiation-mediated damage to cellular DNA.Q36062298
The isolation and characterisation of a new type of dimeric adenine photoproduct in UV-irradiated deoxyadenylatesQ36117047
Mechanistic studies of the spore photoproduct lyase via a single cysteine mutationQ36252717
NMR structures of damaged DNA.Q36389675
I will survive: DNA protection in bacterial sporesQ36750425
Chemical syntheses of oligodeoxyribonucleotides containing spore photoproductQ36787871
Dynamic determination of the functional state in photolyase and the implication for cryptochromeQ37088670
DNA repair and free radicals, new insights into the mechanism of spore photoproduct lyase revealed by single amino acid substitutionQ37142834
Spore photoproduct lyase catalyzes specific repair of the 5R but not the 5S spore photoproductQ37257867
Redox signaling between DNA repair proteins for efficient lesion detectionQ37340789
Structural biology of DNA photolyases and cryptochromesQ37504187
Spore photoproduct: a key to bacterial eternal lifeQ37627861
Chemical investigation of light induced DNA bipyrimidine damage and repairQ37809480
The cryptochromes: blue light photoreceptors in plants and animals.Q37869931
The variety of UV-induced pyrimidine dimeric photoproducts in DNA as shown by chromatographic quantification methodsQ38097712
Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repairQ38333600
Theoretical Study on the Repair Mechanism of the (6−4) Photolesion by the (6−4) PhotolyaseQ38339813
The structure of d(TpA), the major photoproduct of thymidylyl-(3'5')-deoxyadenosineQ39716125
Thermodynamic and base-pairing studies of matched and mismatched DNA dodecamer duplexes containing cis-syn, (6-4) and Dewar photoproducts of TT.Q39724689
Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cellsQ40778478
Structure and function of DNA photolyaseQ40803269
Photochemistry, photophysics, and mechanism of pyrimidine dimer repair by DNA photolyaseQ40828093
No "End of History" for photolyasesQ40969808
A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energyQ41203605
Photocarcinogenesis: an overviewQ41596015
High-resolution crystal structure of the intramolecular d(TpA) thymine-adenine photoadduct and its mechanistic implicationsQ41988147
Synthesis and stereochemical assignment of DNA spore photoproduct analoguesQ42689081
Purification and characterization of a type III photolyase from Caulobacter crescentusQ43106739
DNA photolyase: is the nonproductive back electron transfer really much slower than forward transfer?Q43206665
DNA repair by photolyase: a novel substrate with low background absorption around 265 nm for transient absorption studies in the UV.Q43226339
Electronic structure of (6-4) DNA photoproduct repair involving a non-oxetane pathwayQ43239752
Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions.Q43591673
Isolation and mass spectrometric characterization of dimeric adenine photoproducts in oligodeoxynucleotidesQ43642994
DNA excited-state dynamics: ultrafast internal conversion and vibrational cooling in a series of nucleosidesQ43768693
Direct H atom abstraction from spore photoproduct C-6 initiates DNA repair in the reaction catalyzed by spore photoproduct lyase: evidence for a reversibly generated adenosyl radical intermediateQ43922769
Stepwise cycloreversion of oxetane radical cations with initial C-O bond cleavageQ44016167
Ultrafast decay of electronically excited singlet cytosine via a pi,pi* to n(O),pi* state switchQ44024059
A (6-4) photolyase model: repair of DNA (6-4) lesions requires a reduced and deprotonated flavinQ44255398
Hydrogen transfer in SAM-mediated enzymatic radical reactionsQ44379183
Ultrafast internal conversion of excited cytosine via the lowest pipi electronic singlet stateQ44498774
Efficient deactivation of a model base pair via excited-state hydrogen transfer.Q45171568
P433issue1
P304page(s)1-14
P577publication date2013-10-25
P1433published inPhotochemistry and PhotobiologyQ3381560
P1476titleFormation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions
P478volume90

Reverse relations

cites work (P2860)
Q56990012A Prokaryotic (6-4) Photolyase with a DMRL Chromophore and an Iron-Sulfur Cluster
Q39021795A Review of Spectroscopic and Biophysical-Chemical Studies of the Complex of Cyclobutane Pyrimidine Dimer Photolyase and Cryptochrome DASH with Substrate DNA.
Q38587983DNA Repair and Chromosomal Translocations
Q46455563Direct observation of a deoxyadenosyl radical in an active enzyme environment.
Q92680961Fabrication and Characterization of Hollow Microcapsules from Polyelectrolytes Bearing Thymine Pendant Groups for Ultraviolet-B (UVB)-Induced Crosslinking
Q30400996Insights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine Residue
Q35816266Key Amino Acids in the Bacterial (6-4) Photolyase PhrB from Agrobacterium fabrum
Q38396431Molecular and physiological effects of environmental UV radiation on fungal conidia.
Q38298148Molecular regulation of UV-induced DNA repair
Q92447188Non-Coding RNAs Participate in the Regulation of CRY-DASH in the Growth and Early Development of Saccharina japonica (Laminariales, Phaeophyceae)
Q36244682Photochemistry and Photobiology of the Spore Photoproduct: A 50-Year Journey
Q51016000Probing deactivation pathways of DNA nucleobases by two-dimensional electronic spectroscopy: first principles simulations.
Q39043279Repair of (6-4) Lesions in DNA by (6-4) Photolyase: 20 Years of Quest for the Photoreaction Mechanism.
Q53126688Repair of a Dimeric Azetidine Related to the Thymine-Cytosine (6-4) Photoproduct by Electron Transfer Photoreduction.
Q26863308Spore photoproduct lyase: the known, the controversial, and the unknown
Q38288631Spore photoproduct within DNA is a surprisingly poor substrate for its designated repair enzyme-The spore photoproduct lyase
Q54249212Survival and SOS response induction in ultraviolet B irradiated Escherichia coli cells with defective repair mechanisms.
Q41899080Theoretical analyses on a flipping mechanism of UV-induced DNA damage

Search more.