The function of Fcγ receptors in dendritic cells and macrophages

scientific article published on 21 January 2014

The function of Fcγ receptors in dendritic cells and macrophages is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1010804907
P356DOI10.1038/NRI3582
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/nri3582
P698PubMed publication ID24445665
P5875ResearchGate publication ID259826273

P50authorBart LambrechtQ18402373
Martin GuilliamsQ48148352
Yvan SaeysQ48577555
Pierre BruhnsQ56435969
P2093author name stringHamida Hammad
P2860cites workActivating and inhibitory IgG Fc receptors on human DCs mediate opposing functionsQ24532135
Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)Q24633690
MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cellsQ24643634
Exploring the full spectrum of macrophage activationQ24653754
Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein functionQ24684586
A role for IgG immune complexes during infection with the intracellular pathogen LeishmaniaQ25256801
Translating basic mechanisms of IgG effector activity into next generation cancer therapiesQ26991899
Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targetsQ28140238
The complexity of antibody-dependent enhancement of dengue virus infectionQ28250383
Functional characteristics of the high affinity IgG receptor, FcγRI.Q37843085
Antibody-Fc receptor interactions in protection against intracellular pathogens.Q37853942
Properties of mouse and human IgG receptors and their contribution to disease modelsQ38005653
The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseasesQ38042219
Regulation of Phagocytosis and [Ca 2+ ] i Flux by Distinct Regions of an Fc ReceptorQ38514533
Staphylococcus aureus-induced plasmacytoid dendritic cell activation is based on an IgG-mediated memory responseQ39943911
TGF-beta 1 suppresses [correction of supresses] myeloid Fc gamma receptor function by regulating the expression and function of the common gamma-subunit.Q40653215
Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivoQ40749020
Secretory phospholipase A(2) elicits proinflammatory changes and upregulates the surface expression of fas ligand in monocytic cells: potential relevance for atherogenesisQ40757763
Regulated expression and inhibitory function of Fcgamma RIIb in human monocytic cellsQ40763824
The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complexQ40924258
syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transport to lysosomesQ41015817
Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.Q41166947
Fc receptor biologyQ41464279
Tyrosine-containing motif that transduces cell activation signals also determines internalization and antigen presentation via type III receptors for IgGQ41613221
Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytesQ41618456
Distinct cell-specific control of autoimmunity and infection by FcgammaRIIbQ42006236
Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitroQ42022012
Plasmacytoid dendritic cells of melanoma patients present exogenous proteins to CD4+ T cells after Fc gamma RII-mediated uptakeQ42091841
A general requirement for FcγRIIB co-engagement of agonistic anti-TNFR antibodiesQ42445183
Immune complexes inhibit differentiation, maturation, and function of human monocyte-derived dendritic cells.Q42514349
Fc gamma receptors regulate immune activation and susceptibility during Mycobacterium tuberculosis infectionQ42646009
Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergenQ43468956
FcγRIII (CD16) equips immature 6-sulfo LacNAc-expressing dendritic cells (slanDCs) with a unique capacity to handle IgG-complexed antigensQ44620514
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differencesQ46516651
Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets.Q46876439
Fcγ receptor IIb strongly regulates Fcγ receptor-facilitated T cell activation by dendritic cellsQ47681830
IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10Q50335926
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alphaQ28251443
Fcgamma receptors: old friends and new family membersQ28291895
Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and futureQ28292558
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infectionQ28504795
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cellsQ28508363
Accelerated antigen presentation and elicitation of humoral response in vivo by FcgammaRIIB- and FcgammaRI/III-mediated immune complex uptakeQ28511010
FcgammaRIV is a mouse IgE receptor that resembles macrophage FcepsilonRI in humans and promotes IgE-induced lung inflammationQ28588375
FcgammaRIV: a novel FcR with distinct IgG subclass specificityQ28594064
The chemokine system in diverse forms of macrophage activation and polarizationQ29547719
Fcgamma receptors as regulators of immune responsesQ29615584
Recognition of cytosolic DNA activates an IRF3-dependent innate immune responseQ29616156
The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed settingQ29618424
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophagesQ29620142
A lineage of myeloid cells independent of Myb and hematopoietic stem cellsQ29620147
Evidence That Maternal Dengue Antibodies Are Important in the Development of Dengue Hemorrhagic Fever in InfantsQ29620637
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEQ29620722
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2Q29622852
Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cellsQ33206586
Cytokine-regulated expression and inhibitory function of FcgammaRIIB1 and -B2 receptors in human dendritic cellsQ33225793
Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptorQ33335777
IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activityQ33347095
Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune diseaseQ33347581
Classical dengue hemorrhagic fever resulting from two dengue infections spaced 20 years or more apart: Havana, Dengue 3 epidemic, 2001-2002.Q33367336
Intravenous immunoglobulin ameliorates ITP via activating Fc gamma receptors on dendritic cellsQ33371273
Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivoQ33398737
The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapyQ33405125
Intravenous immunoglobulin therapy: how does IgG modulate the immune system?Q33405903
Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages.Q33518557
Murine IgG1 and IgG3 isotype switch variants promote phagocytosis of Cryptococcus neoformans through different receptorsQ33562297
Fcgamma receptors: structure, function and role as genetic risk factors in SLEQ33697484
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.Q33731760
Fc receptor signaling and trafficking: a connection for antigen processingQ33815451
Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cellsQ33865201
Plasmacytoid dendritic cells take up opsonized antigen leading to CD4+ and CD8+ T cell activation in vivoQ33907906
Differential modulation of stimulatory and inhibitory Fc gamma receptors on human monocytes by Th1 and Th2 cytokinesQ33928636
Sabotage and exploitation in macrophages parasitized by intracellular protozoansQ33984255
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis.Q50787445
Human inflammatory dendritic cells induce Th17 cell differentiation.Q50917340
IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.Q51002504
Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity.Q52486393
Regulated expression of FcgammaR in human dendritic cells controls cross-presentation of antigen-antibody complexes.Q53584954
Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFNα secretion.Q53901177
Dominant expression of the inhibitory FcgammaRIIB prevents antigen presentation by murine plasmacytoid dendritic cells.Q54454274
CD64 Expression Distinguishes Monocyte-Derived and Conventional Dendritic Cells and Reveals Their Distinct Role during Intramuscular ImmunizationQ57275355
Facilitated antigen uptake and timed exposure to TLR ligands dictate the antigen-presenting potential of plasmacytoid DCsQ57920497
Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivoQ58234959
Activation of Human Plasmacytoid Dendritic Cells by TLR9 Impairs Fc RII-Mediated Uptake of Immune Complexes and Presentation by MHC Class IIQ58619971
Inhibition of maturation and function of dendritic cells by intravenous immunoglobulinQ58864690
Antibodies to Hepatitis B Surface Antigen Potentiate the Response of Human T Lymphocyte Clones to the Same AntigenQ72811339
Targeting apoptotic tumor cells to Fc gamma R provides efficient and versatile vaccination against tumors by dendritic cellsQ78946086
Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammationQ79445161
FcRn: an IgG receptor on phagocytes with a novel role in phagocytosisQ79930067
Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responsesQ80257343
FcgammaRIIB deficiency leads to autoimmunity and a defective response to apoptosis in Mrl-MpJ miceQ81022674
HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayersQ81468722
Cell surface recycling of internalized antigen permits dendritic cell priming of B cellsQ81476297
Fc gamma RIIB regulates nasal and oral tolerance: a role for dendritic cellsQ81672093
Control of infection with Leishmania major in susceptible BALB/c mice lacking the common gamma-chain for FcR is associated with reduced production of IL-10 and TGF-beta by parasitized cellsQ81724341
Intracellular antibody-mediated immunity and the role of TRIM21Q82069556
Fcgamma receptor-mediated antigen uptake by lung DC contributes to allergic airway hyper-responsiveness and inflammationQ82863640
Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritisQ83239526
The inhibitory Fc gamma IIb receptor dampens TLR4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent diseaseQ84521125
Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cellsQ85259274
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cellsQ85634389
IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling.Q36793403
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responsesQ36882237
Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.Q36903830
FcRn: the neonatal Fc receptor comes of age.Q36912134
Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.Q36959840
Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in miceQ36967895
Differential signal transduction, membrane trafficking, and immune effector functions mediated by FcgammaRI versus FcgammaRIIaQ37078202
Activation of the MAPK, ERK, following Leishmania amazonensis infection of macrophagesQ37097916
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF.Q37194936
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexesQ37206862
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.Q37222231
Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic miceQ37350204
Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skinQ37405187
Inhibitory ITAMs as novel regulators of immunity.Q37631690
The MHC class I-like Fc receptor promotes humorally mediated autoimmune diseaseQ37698818
Deciphering the transcriptional network of the dendritic cell lineageQ37700905
FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.Q37736263
Modulation of host cell function by Legionella pneumophila type IV effectorsQ37798551
IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation.Q33987889
Modulation of innate immunity by Toxoplasma gondii virulence effectorsQ34033981
Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergenQ34161524
Antibodies protect against intracellular bacteria by Fc receptor-mediated lysosomal targeting.Q34377438
Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissueQ34471984
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasisQ34646876
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytesQ34650719
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexesQ34671059
Immune complex-mediated antigen presentation induces tumor immunityQ34793164
Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skinQ35030843
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cellsQ35049100
Transcriptomes of the B and T lineages compared by multiplatform microarray profilingQ35117503
Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors.Q35834611
Deletion of fcgamma receptor IIB renders H-2(b) mice susceptible to collagen-induced arthritisQ35834623
Characterization of resident and migratory dendritic cells in human lymph nodesQ35894149
Mast cells and companyQ35927793
Autonomous phagosomal degradation and antigen presentation in dendritic cellsQ36221894
Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunityQ36227843
Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptorsQ36228422
Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasiaQ36229077
Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response programQ36229419
Signaling through Fc gamma RIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation.Q36229572
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cellsQ36333494
Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalizationQ36367948
Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmaniasisQ36368360
Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cellsQ36369741
Constitutive versus activation-dependent cross-presentation of immune complexes by CD8(+) and CD8(-) dendritic cells in vivoQ36371253
Selective suppression of interleukin-12 induction after macrophage receptor ligationQ36377302
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.Q36402668
FcgammaRIIb balances efficient pathogen clearance and the cytokine-mediated consequences of sepsis.Q36403918
Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activationQ36579451
Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profilingQ36673501
Dependence of antibody-mediated presentation of antigen on FcRnQ36756942
P2507corrigendum / erratumErratum: The function of Fcγ receptors in dendritic cells and macrophagesQ57920432
P433issue2
P921main subjectmacrophageQ184204
dendritic cellQ506253
P304page(s)94-108
P577publication date2014-01-21
P1433published inNature Reviews ImmunologyQ43355
P1476titleThe function of Fcγ receptors in dendritic cells and macrophages
P478volume14

Reverse relations

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Q64949957Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice.
Q97883509Impact of Plasma Membrane Domains on IgG Fc Receptor Function
Q36182299Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation
Q40745788Improved Survival of HER2+ Breast Cancer Patients Treated with Trastuzumab and Chemotherapy Is Associated with Host Antibody Immunity against the HER2 Intracellular Domain
Q26781290Induction of Regulatory T Cells by Intravenous Immunoglobulin: A Bridge between Adaptive and Innate Immunity
Q94554560Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection
Q64925019Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms.
Q55387054Innate immune receptors drive dengue virus immune activation and disease.
Q38847426Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1.
Q55044025Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Q52800548Intraperitoneal Immunization with Cry1Ac Protoxin from Bacillus thuringiensis Provokes Upregulation of Fc-Gamma-II/and Fc-Gamma-III Receptors Associated with IgG in the Intestinal Epithelium of Mice.
Q60647752Intravenous immune globulin suppresses angiogenesis in mice and humans
Q59351768Investigation of tunable acetalated dextran microparticle platform to optimize M2e-based influenza vaccine efficacy
Q28081718Is infant immunization by breastfeeding possible?
Q90690112Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype
Q64913821Leishmania infantum Virulence Factor A2 Protein: Linear B-Cell Epitope Mapping and Identification of Three Main Linear B-Cell Epitopes in Vaccinated and Naturally Infected Dogs.
Q102211190Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19
Q46572905Ligation of FcγR Alters Phagosomal Processing of Protein via Augmentation of NADPH Oxidase Activity
Q40278997Lipopolysaccharide-Elicited TSLPR Expression Enriches a Functionally Discrete Subset of Human CD14+ CD1c+ Monocytes
Q41731948Loading dendritic cells with PLA-p24 nanoparticles or MVA expressing HIV genes induces HIV-1-specific T cell responses.
Q35113222Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice
Q53393080Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.
Q41842699Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells.
Q26783493M2e-Based Universal Influenza A Vaccines
Q27007951Macrophage proliferation, provenance, and plasticity in macroparasite infection
Q35641157Macrophages Are Phenotypically and Functionally Diverse across Tissues in Simian Immunodeficiency Virus-Infected and Uninfected Asian Macaques
Q39331723Macrophages as Effectors of Acute and Chronic Allograft Injury
Q91868507Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection
Q26853371Mass cytometry: a highly multiplexed single-cell technology for advancing drug development
Q47574862Maternal IgG immune complexes induce food allergen-specific tolerance in offspring.
Q58775766Messing with the Sentinels-The Interaction of with Dendritic Cells
Q26781338Modes of Antigen Presentation by Lymph Node Stromal Cells and Their Immunological Implications
Q38760836Modulating immunogenicity of factor IX by fusion to an immunoglobulin Fc domain: a study using a hemophilia B mouse model
Q48278134Modulation of IgG1 immunoeffector function by glycoengineering of the GDP-fucose biosynthesis pathway.
Q37626070Modulation of Microglial Cell Fcγ Receptor Expression Following Viral Brain Infection
Q50133260Modulation of protein A binding allows single-step purification of mouse bispecific antibodies that retain FcRn binding.
Q26825548Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases
Q39258320Monocyte differentiation and antigen-presenting functions
Q38615349Mouse and human FcR effector functions
Q37677278Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles
Q47148202Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.
Q90341760Murine macrophage TLR2-FcγR synergy via FcγR licensing of IL-6 cytokine mRNA ribosome binding and translation
Q39364012Myeloperoxidase-Oxidized LDLs Enhance an Anti-Inflammatory M2 and Antioxidant Phenotype in Murine Macrophages.
Q40134053Near-Infrared 1064 nm Laser Modulates Migratory Dendritic Cells To Augment the Immune Response to Intradermal Influenza Vaccine.
Q55314061Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes.
Q90485498OMIP-051 - 28-color flow cytometry panel to characterize B cells and myeloid cells
Q38991048Old dogs-new tricks: immunoregulatory properties of C3 and C5 cleavage fragments
Q50073556Personalized medicine with biologics for severe type 2 asthma: current status and future prospects.
Q90211749Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients
Q93018133Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival
Q40284594Porcine Dendritic Cells as an In Vitro Model to Assess the Immunological Behaviour of Streptococcus suis Subunit Vaccine Formulations and the Polarizing Effect of Adjuvants
Q37074015Protection against Streptococcus suis Serotype 2 Infection Using a Capsular Polysaccharide Glycoconjugate Vaccine
Q34542687Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein
Q92471671Reciprocal immune enhancement of dengue and Zika virus infection in human skin
Q40039898Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice.
Q58554208Recombinant factor VIII Fc fusion protein drives regulatory macrophage polarization
Q28066034Regulation of immunity during visceral Leishmania infection
Q89978292Reprogramming the Constant Region of Immunoglobulin G Subclasses for Enhanced Therapeutic Potency against Cancer
Q64107587Research and development of new tuberculosis vaccines: a review
Q38782706Role of Fc-FcγR interactions in the antitumor activity of therapeutic antibodies
Q30855264Screening genes crucial for pediatric pilocytic astrocytoma using weighted gene coexpression network analysis combined with methylation data analysis
Q92538845Selective Engagement of FcγRIV by a M2e-Specific Single Domain Antibody Construct Protects Against Influenza A Virus Infection
Q33724997Sendai virus-based RSV vaccine protects against RSV challenge in an in vivo maternal antibody model
Q35946462Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice.
Q28553042Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect
Q39189720Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella.
Q45342736Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen
Q90730861Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium
Q38615376Structural analysis of Fc/FcγR complexes: a blueprint for antibody design.
Q40388373Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI.
Q59135850Subcutaneous immunotherapy induces alterations in monocytes and dendritic cells homeostasis in allergic rhinitis patients
Q35102339Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection
Q33443533Sustained Remission in Patients with Primary Immune Thrombocytopenia after Romiplostim Tapering and Discontinuation: A Case Series in Real Life Management in Spain.
Q36296686Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate
Q53396845Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.
Q64102267Targeting the Antibody Checkpoints to Enhance Cancer Immunotherapy-Focus on FcγRIIB
Q64240465The Binding of Human IgG to Minipig FcγRs - Implications for Preclinical Assessment of Therapeutic Antibodies
Q89861405The Diverse Functions of the Ubiquitous Fcγ Receptors and Their Unique Constituent, FcRγ Subunit
Q35665034The Effects of Antigen-Specific IgG1 Antibody for the Pulmonary-Hypertension-Phenotype and B Cells for Inflammation in Mice Exposed to Antigen and Fine Particles from Air Pollution
Q92239387The Neonatal Fc Receptor (FcRn): A Misnomer?
Q39088502The Role and Function of Fcγ Receptors on Myeloid Cells
Q26852988The Role of FcRn in Antigen Presentation
Q41354182The VEGF-A inhibitor sFLT-1 improves renal function by reducing endothelial activation and inflammation in a mouse model of type 1 diabetes
Q47103062The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages.
Q64945497The inflammatory function of human IgA.
Q37493320The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis
Q33817936The journey from stem cell to macrophage
Q38936522The life cycle of phagosomes: formation, maturation, and resolution
Q47810222The pathophysiology of anaphylaxis
Q58714558The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens
Q38365223The role of FcεRI expressed in dendritic cells and monocytes
Q28075279The role of genetics and antibodies in sepsis
Q38920840The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages.
Q49684254The roles of CSFs on the functional polarization of tumor-associated macrophages.
Q38879903The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state
Q36383442The transcriptional profile of coronary arteritis in Kawasaki disease
Q90053512Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells
Q49242675Tolerance through Education: How Tolerogenic Dendritic Cells Shape Immunity.
Q38896842Trastuzumab triggers phagocytic killing of high HER2 cancer cells in vitro and in vivo by interaction with Fcγ receptors on macrophages
Q38232105Type I and type II Fc receptors regulate innate and adaptive immunity
Q54217613Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis.
Q83230893Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
Q64057499Use of Dendritic Cell Receptors as Targets for Enhancing Anti-Cancer Immune Responses
Q28545783Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis
Q35823060Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell-Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype Diversification
Q37244315miR-24, miR-30b and miR-142-3p interfere with antigen processing and presentation by primary macrophages and dendritic cells

Q57920432Erratum: The function of Fcγ receptors in dendritic cells and macrophagesmain subjectP921

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