scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Lars M. Ittner | Q30347436 |
Michael Kassiou | Q48744540 | ||
P2093 | author name string | Sook W Chua | |
P2860 | cites work | Alzheimer's Disease | Q22248111 |
Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function | Q24296269 | ||
Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide | Q24546891 | ||
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28 | Q24599479 | ||
The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders | Q24641816 | ||
Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies | Q24642726 | ||
Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma | Q24649929 | ||
Neuropathological stageing of Alzheimer-related changes | Q27860862 | ||
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide | Q28131750 | ||
Inflammation and Alzheimer's disease | Q28138617 | ||
Peripheral benzodiazepine receptors and mitochondrial function | Q28201926 | ||
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects | Q28249253 | ||
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases | Q28269333 | ||
Ligand for translocator protein reverses pathology in a mouse model of Alzheimer's disease | Q28290730 | ||
Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis | Q28301125 | ||
Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis | Q28303440 | ||
The mitochondrial permeability transition pore and its role in cell death | Q29614183 | ||
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders | Q29618148 | ||
Mouse TSPO in a lipid environment interacting with a functionalized monolayer | Q30418916 | ||
Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state | Q30649552 | ||
Microglial activation and amyloid deposition in mild cognitive impairment: a PET study | Q33634089 | ||
Convergence of amyloid-beta and tau pathologies on mitochondria in vivo | Q33876147 | ||
Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation | Q34171364 | ||
Molecular imaging of microglia/macrophages in the brain | Q34276818 | ||
Mitochondrial benzodiazepine receptors regulate steroid biosynthesis | Q34325284 | ||
Development of ligands for the peripheral benzodiazepine receptor | Q34547615 | ||
Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor | Q34612661 | ||
Neuroprotective effect of Ro5-4864 following brain injury | Q34826756 | ||
A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR | Q34872399 | ||
Neuroprotective effects of a ligand of translocator protein-18 kDa (Ro5-4864) in experimental diabetic neuropathy. | Q34996330 | ||
Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding | Q35050152 | ||
Inflammatory processes in Alzheimer's disease | Q35201137 | ||
Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture. | Q35202286 | ||
Mitochondrial Benzodiazepine Receptors and the Regulation of Steroid Biosynthesis | Q35229114 | ||
In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders | Q35654128 | ||
Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]R05-4864 and [3H]PK 11195, by thermodynamic studies | Q51852591 | ||
Evaluation of [¹²³I]-CLINDE as a potent SPECT radiotracer to assess the degree of astroglia activation in cuprizone-induced neuroinflammation. | Q54378366 | ||
A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation | Q36684216 | ||
In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease. | Q36953874 | ||
Pregnenolone biosynthesis in C6-2B glioma cell mitochondria: regulation by a mitochondrial diazepam binding inhibitor receptor | Q37044498 | ||
Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides | Q37130302 | ||
Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease. | Q37153379 | ||
Imaging microglial activation during neuroinflammation and Alzheimer's disease | Q37340359 | ||
PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET. | Q37351230 | ||
The translocator protein (18 kDa): central nervous system disease and drug design | Q37365598 | ||
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice | Q37414108 | ||
Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta | Q37555305 | ||
Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders | Q37814088 | ||
Amyloid-β and tau--a toxic pas de deux in Alzheimer's disease | Q37824813 | ||
Shedding light on the mitochondrial permeability transition. | Q37850094 | ||
Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature | Q37982377 | ||
Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria | Q38335116 | ||
Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals | Q39864742 | ||
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression | Q40301497 | ||
Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line | Q41249632 | ||
Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum | Q41964688 | ||
Structural and functional study of reconstituted peripheral benzodiazepine receptor | Q43631731 | ||
In-vivo measurement of activated microglia in dementia | Q43713539 | ||
Etifoxine analgesia in experimental monoarthritis: a combined action that protects spinal inhibition and limits central inflammatory processes. | Q43869315 | ||
In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding. | Q44402442 | ||
Assessment of neuroinflammation and microglial activation in Alzheimer's disease with radiolabelled PK11195 and single photon emission computed tomography. A pilot study | Q44490089 | ||
Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine | Q44786130 | ||
Cell surface localization of the peripheral-type benzodiazepine receptor (PBR) in adrenal cortex | Q44845409 | ||
Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum | Q45296984 | ||
Differential effect of detergents on [3H]Ro 5-4864 and [3H]PK 11195 binding to peripheral-type benzodiazepine-binding sites | Q46227832 | ||
Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study | Q46373170 | ||
Binding of [3H]Ro 5-4864 and [3H]PK 11195 to cerebral cortex and peripheral tissues of various species: species differences and heterogeneity in peripheral benzodiazepine binding sites | Q46596862 | ||
Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand | Q46614777 | ||
Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding | Q46639005 | ||
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ | Q46779933 | ||
Dihydropyridine and peripheral type benzodiazepine binding sites: subcellular distribution and molecular size determination | Q47216704 | ||
In situ molecular weight determination of brain and peripheral benzodiazepine binding sites | Q47274987 | ||
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice | Q47814284 | ||
In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients | Q48151150 | ||
Reactive astrocytes overexpress TSPO and are detected by TSPO positron emission tomography imaging. | Q48415784 | ||
Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study | Q48426445 | ||
Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease | Q48512773 | ||
Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis | Q48532076 | ||
Peripheral benzodiazepine binding sites in Alzheimer's disease frontal and temporal cortex | Q48737055 | ||
P433 | issue | 4 | |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 439-448 | |
P577 | publication date | 2014-04-01 | |
P1433 | published in | Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders | Q15760319 |
P1476 | title | The translocator protein as a drug target in Alzheimer's disease | |
P478 | volume | 14 |