Role of non-coding RNAs in pancreatic beta-cell development and physiology

scientific article published on 15 April 2014

Role of non-coding RNAs in pancreatic beta-cell development and physiology is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/APHA.12285
P698PubMed publication ID24666639
P5875ResearchGate publication ID261102108

P50authorLena EliassonQ38323396
Jonathan Lou S EsguerraQ57320830
P2093author name stringJ L S Esguerra
P2860cites workHigh glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expressionQ21136357
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miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cellsQ24645027
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Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiationQ24655701
miR-375 maintains normal pancreatic alpha- and beta-cell massQ24657284
Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki ratQ27347966
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
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MicroRNAs: small RNAs with a big role in gene regulationQ27860896
Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patientsQ27863911
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cellsQ28251177
A pancreatic islet-specific microRNA regulates insulin secretionQ28292726
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Argonaute2 mediates compensatory expansion of the pancreatic β cellQ30414353
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetesQ30416868
Epigenomic plasticity enables human pancreatic α to β cell reprogramming.Q30536573
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PIWI proteins and PIWI-interacting RNAs in the somaQ34039572
Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.Q34117281
MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cellsQ34316436
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Topological organization of multichromosomal regions by the long intergenic noncoding RNA FirreQ34400074
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Cell-type-specific signatures of microRNAs on target mRNA expressionQ34479693
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesisQ34571691
Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcriptionQ34908066
Glucose-stimulated signaling pathways in biphasic insulin secretionQ35018519
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretionQ35112943
Insulin granule dynamics in pancreatic beta cellsQ35184211
L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathwayQ35696480
Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetesQ36047543
Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD miceQ36047577
MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cellsQ36225727
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesityQ36290327
Non-invasive in vivo imaging of pancreatic β-cell function and survival - a perspectiveQ36485583
Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotypingQ36503772
Islet β cell mass in diabetes and how it relates to function, birth, and deathQ36745536
Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions.Q37132484
mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stabilityQ37134416
Novel aspects of the molecular mechanisms controlling insulin secretionQ37176911
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204Q37330393
Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretionQ37431971
Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets.Q37599098
Genetic basis of beta-cell dysfunction in man.Q37611949
ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS.Q37801219
Diabetes mellitus, a microRNA-related disease?Q37855088
The exocytotic machineryQ38179061
A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretionQ38271856
Syntaxin-1a is a direct target of miR-29a in insulin-producing β-cells.Q39211230
MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretionQ39287052
Functional subdivision of islets of Langerhans and possible role of D cellsQ39356963
MicroRNA-15a positively regulates insulin synthesis by inhibiting uncoupling protein-2 expressionQ39621720
Functional specificity among ribosomal proteins regulates gene expressionQ39666047
Munc 18-1 and granuphilin collaborate during insulin granule exocytosisQ40022400
Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAsQ40028213
MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillationQ40036365
Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cellsQ40841075
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretionQ40871524
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoformsQ41729392
miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors.Q41899866
MicroRNAs are essential for stretch-induced vascular smooth muscle contractile differentiation via microRNA (miR)-145-dependent expression of L-type calcium channelsQ42183020
Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent isletsQ42487818
The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetesQ43586741
Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.Q45904927
MicroRNAs and Cellular PhenotypyQ46084261
The relationship between non-protein-coding DNA and eukaryotic complexity.Q51994672
P433issue2
P921main subjectphysiologyQ521
P304page(s)273-284
P577publication date2014-04-15
P1433published inActa PhysiologicaQ2662816
P1476titleRole of non-coding RNAs in pancreatic beta-cell development and physiology
P478volume211

Reverse relations

cites work (P2860)
Q39659496A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells
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