Concise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells?

scientific article published on September 2014

Concise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.1720
P698PubMed publication ID24740867

P50authorMajlinda LakoQ21402747
Lyle ArmstrongQ60873503
Miodrag StojkovicQ96960974
P2093author name stringJumana Al-Aama
P2860cites workDNA methylation age of human tissues and cell typesQ21183994
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The ageing systemic milieu negatively regulates neurogenesis and cognitive function.Q24599219
The aging processQ24616537
Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblastsQ24634195
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageingQ24649634
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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageingQ29615155
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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulationQ33293158
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Chromatin modifications: the driving force of senescence and aging?Q33588661
DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cellsQ33621598
Widespread and tissue specific age-related DNA methylation changes in mice.Q33736551
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansionQ33777928
Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell agingQ33891793
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Regeneration, stem cells, and the evolution of tumor suppressionQ37371334
Tissue resident stem cells: till death do us partQ37429379
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Chromatin modification and senescence.Q37986805
Proteostasis and aging of stem cellsQ38149484
Reduction of myoblast differentiation following multiple population doublings in mouse C2 C12 cells: a model to investigate ageing?Q39492987
α1-Adrenergic drugs modulate differentiation and cell death of human erythroleukemia cells through non adrenergic mechanismQ39502375
A determining influence for CpG dinucleotides on nucleosome positioning in vitroQ39946027
Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cellsQ39948728
Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosisQ40532914
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Human iPSC-based modeling of late-onset disease via progerin-induced agingQ41868474
A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defectsQ42815540
Genotoxic damage of human adipose-tissue derived mesenchymal stem cells triggers their terminal differentiation.Q43281360
Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline.Q43414778
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.Q44770129
Cellular aging is associated with increased ubiquitylation of histone H2B in yeast telomeric heterochromatinQ46623973
Marked mitochondrial DNA sequence heterogeneity in single CD34+ cell clones from normal adult bone marrowQ47612283
Age-specific changes of mesenchymal stem cells are paralleled by upregulation of CD106 expression as a response to an inflammatory environment.Q48932892
Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells.Q53235308
Stem cells, aging, niche, adhesion and Cdc42: a model for changes in cell-cell interactions and hematopoietic stem cell aging.Q53561950
In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes.Q54779196
Defects in multiple complexes of the respiratory chain are present in ageing human colonic cryptsQ33922286
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Accumulation of mtDNA variations in human single CD34+ cells from maternally related individuals: effects of aging and family genetic background.Q34130756
Lamin a truncation in Hutchinson-Gilford progeria.Q34191501
Genome-wide methylation profiles reveal quantitative views of human aging ratesQ34313440
An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.Q34332081
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Nuclear and chromatin reorganization during cell senescence and aging - a mini-reviewQ34540621
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Regenerative capacity of old muscle stem cells declines without significant accumulation of DNA damageQ34737490
The ageing epigenome: damaged beyond repair?Q34980757
Senescence as a mode of tumor suppressionQ35034137
The Golgi apparatus at the cell centreQ35041098
DNA damage and ageing: new-age ideas for an age-old problemQ35153827
The Free Radical Theory of AgingQ35568805
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypesQ35611684
Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.Q35647543
Increased hematopoietic stem cell mobilization in aged miceQ35849168
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenationQ35947877
Impact of genome instability on transcription regulation of aging and senescenceQ35947921
Aging, stem cells and tissue regeneration: lessons from muscleQ36051640
Loss of stem cell regenerative capacity within aged nichesQ36117006
DNA methylation and histone modifications: teaming up to silence genesQ36228564
A link between the accumulation of DNA damage and loss of multi-potency of human mesenchymal stromal cellsQ36516974
Protein homeostasis and molecular chaperones in agingQ36590546
Maintenance and modulation of T cell polarityQ36629861
Imaging of retinal autofluorescence in patients with age-related macular degenerationQ36889119
Rising from the RecQ-age: the role of human RecQ helicases in genome maintenanceQ37021646
Lipofuscin: formation, distribution, and metabolic consequencesQ37023370
'From death, lead me to immortality' - mantra of ageing skeletal muscleQ37065378
Mesenchymal stem cells: a promising candidate in regenerative medicineQ37092851
P433issue9
P921main subjectepigenetic rejuvenationQ107569137
P304page(s)2291-2298
P577publication date2014-09-01
P1433published inStem CellsQ15724411
P1476titleConcise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells?
P478volume32

Reverse relations

cites work (P2860)
Q90301534Effects of High- and Low-LET Radiation on Human Hematopoietic System Reconstituted in Immunodeficient Mice
Q47140121MeCP2 mediated dysfunction in senescent EPCs
Q48058171New advances in understanding stem cell fate and function
Q47743127Protective molecular mechanisms of clusterin against apoptosis in cardiomyocytes

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