Drugs targeting nitric oxide synthase for migraine treatment.

scientific article published on 12 May 2014

Drugs targeting nitric oxide synthase for migraine treatment. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1517/13543784.2014.918953
P698PubMed publication ID24818644

P50authorDavid Della-MorteQ79716968
Piero BarbantiQ57160906
P2093author name stringGabriella Egeo
Cinzia Aurilia
Luisa Fofi
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Nitric oxide synthase inhibition: a new principle in the treatment of migraine attacksQ34469372
The role of nitric oxide (NO) in migraine, tension-type headache and cluster headacheQ34826542
cGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO.Q34831503
Triptan-induced enhancement of neuronal nitric oxide synthase in trigeminal ganglion dural afferents underlies increased responsiveness to potential migraine triggersQ35116532
Rizatriptan in migraineurs with unilateral cranial autonomic symptoms: a double-blind trialQ36052140
Role of nitric oxide synthesis in macrophage antimicrobial activityQ36656920
Concepts of neural nitric oxide-mediated transmissionQ37029494
NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channelsQ37344442
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Neuronal nitric oxide synthase: structure, subcellular localization, regulation, and clinical implicationsQ37418305
No NO, no pain? The role of nitric oxide and cGMP in spinal pain processingQ37469549
Nitric oxide-related drug targets in headacheQ37739589
Pain and analgesia: The dual effect of nitric oxide in the nociceptive systemQ37896960
Nitric oxide and cyclic GMP signaling pathway as a focus for drug developmentQ37897595
CGRP and NO in the trigeminal system: mechanisms and role in headache generationQ38025661
Drugs targeting 5-hydroxytryptamine receptors in acute treatments of migraine attacks. A review of new drugs and new administration forms of established drugsQ38167355
Emerging targets in migraineQ38169593
Efficacy and mechanism of anticonvulsant drugs in migraineQ38185096
The Nitric Oxide Hypothesis of Migraine and Other Vascular HeadachesQ41679790
Nitric oxide synthase inhibitors can antagonize neurogenic and calcitonin gene-related peptide induced dilation of dural meningeal vesselsQ42186934
Unmasking latent dysnociception in healthy subjectsQ42208181
Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attackQ42275734
Systemic nitroglycerin induces Fos immunoreactivity in brainstem and forebrain structures of the rat.Q42275969
Modulation of nitric oxide synthase by nitric oxide donor compounds in migraineQ42459229
The inhibition of nitric oxide-activated poly(ADP-ribose) synthetase attenuates transsynaptic alteration of spinal cord dorsal horn neurons and neuropathic pain in the rat.Q42547439
Does the unfavorable pharmacokinetic and pharmacodynamic profile of the iNOS inhibitor GW273629 lead to inefficacy in acute migraine?Q42613452
The effect of i.v. L-NG methylarginine hydrochloride (L-NMMA: 546C88) on basal and acetazolamide (Diamox) induced changes of blood velocity in cerebral arteries and regional cerebral blood flow in man.Q42653933
CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine.Q42854065
Origin and Co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat.Q43574651
Nitric oxide metabolites, prostaglandins and trigeminal vasoactive peptides in internal jugular vein blood during spontaneous migraine attacksQ43576111
Nitric oxide potentiates response of trigeminal neurones to dural or facial stimulation in the rat.Q43725558
Nitric oxide synthase in spinal cord central sensitization following intradermal injection of capsaicinQ43750641
Increased plasma nitrites in migraine and cluster headache patients in interictal period: basal hyperactivity of L-arginine-NO pathway?Q43981820
L-Arginine/nitric oxide pathway in chronic tension-type headache: relation with serotonin content and secretion and glutamate contentQ44011881
Unilateral cranial autonomic symptoms in migraine.Q44051813
Nitrergic and glutamatergic neuronal mechanisms at the trigeminovascular first-order synapse.Q44912603
Glyceryl trinitrate triggers premonitory symptoms in migraineursQ45003191
Role of central dopaminergic circuitry in pain processing and nitroglycerin-induced hyperalgesiaQ46399203
Fos expression in the trigeminocervical complex of the cat after stimulation of the superior sagittal sinus is reduced by L-NAME.Q48125110
Nitric oxide synthase inhibition lowers activity of neurons with meningeal input in the rat spinal trigeminal nucleusQ48382239
Neurochemical mechanisms of nitroglycerin-induced neuronal activation in rat brain: a pharmacological investigationQ48567339
Lack of efficacy of the selective iNOS inhibitor GW274150 in prophylaxis of migraine headache.Q51535876
NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist, inhibits CGRP release in preclinical migraine modelsQ57023928
Nitric oxide synthase inhibition in migraineQ57024918
A nitric oxide donor (nitroglycerin) triggers genuine migraine attacksQ57025038
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmigraineQ133823
P304page(s)1141-1148
P577publication date2014-05-12
P1433published inExpert Opinion on Investigational DrugsQ5421208
P1476titleDrugs targeting nitric oxide synthase for migraine treatment
P478volume23

Reverse relations

cites work (P2860)
Q36762541Andrographis Paniculata shows anti-nociceptive effects in an animal model of sensory hypersensitivity associated with migraine
Q93081932CGRP and the Trigeminal System in Migraine
Q35952529Evaluation of ADMA-DDAH-NOS axis in specific brain areas following nitroglycerin administration: study in an animal model of migraine
Q59203749Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura: a randomized, double-blind, placebo-controlled, crossover study
Q38974701Headaches: a Review of the Role of Dietary Factors
Q47811794Modulation of inducible nitric oxide synthase (iNOS) expression and cardiovascular responses during static exercise following iNOS antagonism within the ventrolateral medulla
Q91887422Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold
Q39012465Serotonin receptor targeted therapy for migraine treatment: an overview of drugs in phase I and II clinical development.
Q38933713Sleep, headaches and cerebral energy control: a synoptic view.
Q89575368Solid-Phase Synthesis of Substrate-Based Dipeptides and Heterocyclic Pseudo-dipeptides as Potential NO Synthase Inhibitors
Q57021551Triggers, Protectors, and Predictors in Episodic Migraine

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