Present-day anthelmintics and perspectives on future new targets.

scientific article published on 04 June 2014

Present-day anthelmintics and perspectives on future new targets. is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1002063225
P356DOI10.1007/S00436-014-3969-7
P698PubMed publication ID24894082

P50authorAmira TamanQ61142420
P2093author name stringManar Azab
P2860cites workThe global programme to eliminate lymphatic filariasis: health impact after 8 yearsQ21092299
Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysisQ21198915
Artemisinins and synthetic trioxolanes in the treatment of helminth infectionsQ22061831
Current perspectives on the mechanism of action of artemisininsQ22061943
Interventions for treating scabiesQ24244137
Diethylcarbamazine activity against Brugia malayi microfilariae is dependent on inducible nitric-oxide synthase and the cyclooxygenase pathwayQ24815903
Serotonin signaling in Schistosoma mansoni: a serotonin-activated G protein-coupled receptor controls parasite movementQ27331388
Artemisinins: their growing importance in medicineQ27489880
Elimination of human onchocerciasis: History of progress and current feasibility using ivermectin (Mectizan®) monotherapyQ27692519
Mechanism of action of reagents that uncouple oxidative phosphorylationQ28237551
Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysisQ28277486
The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunitsQ28475744
A novel G protein-coupled receptor of Schistosoma mansoni (SmGPR-3) is activated by dopamine and is widely expressed in the nervous systemQ28481302
Characterization of a truncated metabotropic glutamate receptor in a primitive metazoan, the parasitic flatworm Schistosoma mansoniQ34070596
Initial observation on albendazole in combination with cimetidine for the treatment of human cystic echinococcosisQ34341798
Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectinQ34388555
Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelminticsQ34506345
Combination chemotherapy of schistosomiasis in laboratory studies and clinical trialsQ34939414
New policies for using anthelmintics in high risk groupsQ34959693
Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasisQ35126821
Are Ca2+ channels targets of praziquantel action?Q35993816
Treatment strategies underpinning the global programme to eliminate lymphatic filariasisQ36066068
Loa loa encephalopathy temporally related to ivermectin administration reported from onchocerciasis mass treatment programs from 1989 to 2001: implications for the futureQ36287263
Classical transmitters and their receptors in flatwormsQ36434064
Intestinal cestodesQ36925515
Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in ZanzibarQ36947786
Artemisinin derivatives inhibit Toxoplasma gondii in vitro at multiple steps in the lytic cycleQ37090661
Praziquantel treatment in trematode and cestode infections: an updateQ37192109
Developmental expression analysis and immunolocalization of a biogenic amine receptor in Schistosoma mansoniQ37293961
Artemisinin-naphthoquine combination (ARCO) therapy for uncomplicated falciparum malaria in adults of Papua New Guinea: a preliminary report on safety and efficacyQ37325659
Current chemotherapy arsenal for schistosomiasis mansoni: alternatives and challengesQ37405246
Unresolved issues in anthelmintic pharmacology for helminthiases of humansQ37636980
Control of nematode parasites with agents acting on neuro-musculature systems: lessons for neuropeptide ligand discovery.Q37824390
Progress and challenges in the discovery of macrofilaricidal drugsQ37912232
Advances in the discovery and development of trematocidal drugsQ38089167
Artemether shows promising female schistosomicidal and ovicidal effects on the Egyptian strain of Schistosoma mansoni after maturity of infection.Q38856397
Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian childrenQ38860009
Severe reactions to filarial chemotherapy and release of Wolbachia endosymbionts into blood.Q38956749
Triclabendazole in the treatment of human fascioliasis: a community-based studyQ38988844
Triclabendazole and its two main metabolites lack activity against Schistosoma mansoni in the mouse model.Q39126736
Schistosome calcium channel beta subunits. Unusual modulatory effects and potential role in the action of the antischistosomal drug praziquantelQ39143568
Effect of a novel benzimidazole derivative in experimental Schistosoma mansoni infection.Q39338872
Efficacy of ivermectin in the treatment of strongyloidiasis complicating AIDS.Q39530129
Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected miceQ39544928
Investigation of a dopamine receptor in Schistosoma mansoni: functional studies and immunolocalizationQ39834861
The general immunopharmacology of levamisoleQ40287927
Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactionsQ40585819
Target sites of anthelmintics.Q40911396
Neuromuscular physiology and pharmacology of parasitic flatwormsQ41365099
Inhibition of heme aggregation by chloroquine reduces Schistosoma mansoni infectionQ41913699
A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamineQ42665977
Treatment of human pulmonary paragonimiasis with triclabendazole: clinical tolerance and drug efficacyQ42688544
Artemisinins inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense in vitro growthQ42845988
Histamine signalling in Schistosoma mansoni: immunolocalisation and characterisation of a new histamine-responsive receptor (SmGPR-2).Q43080018
Fasciola gigantica: Parasitological and scanning electron microscopy study of the in vitro effects of ivermectin and/or artemetherQ43253916
Volatile components of four Ethiopian Artemisia species extracts and their in vitro antitrypanosomal and cytotoxic activitiesQ43291240
Artemether administered together with haemin damages schistosomes in vitroQ43560771
Assessing the risk of benzimidazole therapy during pregnancyQ43560773
Tegumental changes in 21-day-old Schistosoma mansoni harboured in mice treated with artemetherQ43649169
Evidence for the presence of glutamatergic receptors in adult Schistosoma mansoniQ44188958
Pregnancy outcome after inadvertent ivermectin treatment during community-based distributionQ44310207
The effects of diethylcarbamazine on the ultrastructure of microfilariae of Wuchereria bancrofti in vivo and in vitroQ44791062
Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatmentQ44795124
First insight into the effect of single oral dose therapy with artemisinin-naphthoquine phosphate combination in a mouse model of Schistosoma mansoni infectionQ44917077
Triggering of high-level resistance against Schistosoma mansoni reinfection by artemether in the mouse model.Q45219025
Antiparasitic drugs in neurocysticercosis: albendazole or praziquantel?Q46512180
Experimental trials of an artemisinin derivative in treatment of Schistosoma mansoni infected mice.Q46744090
Effect of mebendazole therapy during pregnancy on birth outcomeQ47631263
Effect of artemether on glucose uptake and glycogen content in Schistosoma japonicum.Q47844348
Mode of action of benzimidazolesQ47969579
Glutamate-mediated signaling in Schistosoma mansoni: a novel glutamate receptor is expressed in neurons and the female reproductive tractQ48061086
In vivo effect of single oral dose of artemether against early juvenile stages of Schistosoma mansoni Egyptian strain.Q51222274
Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice.Q51400781
Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum.Q51456665
Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs.Q52721186
Uncoupling of rat liver mitochondrial oxidative phosphorylation by the fasciolicide triclabendazole and its sulfoxide and sulfone metabolites.Q54243782
The anti-schistosomal drug praziquantel is an adenosine antagonistQ58070149
In vivo and in vitro experiments on the effects of praziquantel on Schistosoma mansoni. A light and electron microscopic studyQ70663091
Treatment of Paragonimus Westermani Infections with BithionolQ71624666
Pharmacotherapy of helminth infectionQ83292712
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)2425-2433
P577publication date2014-06-04
P1433published inParasitology ResearchQ15755242
P1476titlePresent-day anthelmintics and perspectives on future new targets
P478volume113

Reverse relations

cites work (P2860)
Q61811472Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors
Q50055971Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites.
Q39039243MicroRNA-mediated regulation of immune responses to intestinal helminth infections.
Q37541737Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research
Q37123991Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues
Q60921263Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice
Q39003333Target-based molecular modeling strategies for schistosomiasis drug discovery.

Search more.