| scholarly article | Q13442814 |
| P356 | DOI | 10.1111/ECI.12304 |
| P8608 | Fatcat ID | release_vbxvu7bytrfiji6xofldrn2mra |
| P698 | PubMed publication ID | 25066257 |
| P5875 | ResearchGate publication ID | 264243583 |
| P50 | author | Valentina Pecoraro | Q84918702 |
| Lorenzo Moja | Q42707889 | ||
| P2093 | author name string | Silvio Garattini | |
| Luigi Dall'Olmo | |||
| Glauco Cappellini | |||
| P2860 | cites work | Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion | Q48474041 |
| Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats. | Q51239930 | ||
| Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice. | Q51762512 | ||
| Pravastatin enhances beneficial effects of olmesartan on vascular injury of salt-sensitive hypertensive rats, via pleiotropic effects. | Q52575652 | ||
| Effects of long-term administration of HMG-CoA reductase inhibitor, atorvastatin, on stroke events and local cerebral blood flow in stroke-prone spontaneously hypertensive rats. | Q53533469 | ||
| Statin monotherapy attenuates renal injury in a salt-sensitive hypertension model of renal disease. | Q53660438 | ||
| Effects of lipid-lowering agents in the Dahl salt-sensitive rat. | Q54175738 | ||
| Structural mechanism for statin inhibition of HMG-CoA reductase | Q27631717 | ||
| Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints | Q27860640 | ||
| Quantifying heterogeneity in a meta-analysis | Q27860672 | ||
| Meta-analysis in clinical trials | Q27860779 | ||
| Effect of clopidogrel on the inflammatory progression of early atherosclerosis in rabbits model | Q28212194 | ||
| Statin therapy and autoimmune disease: from protein prenylation to immunomodulation | Q28236647 | ||
| Nonindustry-sponsored preclinical studies on statins yield greater efficacy estimates than industry-sponsored studies: a meta-analysis | Q28538894 | ||
| Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions | Q28568345 | ||
| The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats | Q28580779 | ||
| Regulation of the mevalonate pathway | Q29547763 | ||
| Improvement of endothelial function in insulin-resistant carotid arteries treated with pravastatin | Q30307937 | ||
| Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid lowering | Q31807283 | ||
| Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits | Q31956644 | ||
| An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro | Q32033463 | ||
| Statins reduce connexin40 and connexin43 expression in atherosclerotic aorta of rabbits | Q33214144 | ||
| Atorvastatin enhances interleukin-10 levels and improves cardiac function in rats after acute myocardial infarction | Q33331962 | ||
| Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus. | Q33929661 | ||
| Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice | Q34137756 | ||
| Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors | Q34207135 | ||
| Beneficial cardiovascular pleiotropic effects of statins | Q34327115 | ||
| Advances in experimental dyslipidemia and atherosclerosis | Q34368686 | ||
| Effect of combining ACE inhibitor and statin in severe experimental nephropathy | Q34522566 | ||
| Experimental atherosclerosis: a historical overview | Q34537397 | ||
| Cardiovascular effects of acute hypercholesterolemia in rabbits. Reversal with lovastatin treatment | Q34565968 | ||
| Risks of statin use during pregnancy: a systematic review | Q34584493 | ||
| The fetal origins of atherosclerosis: maternal hypercholesterolemia, and cholesterol-lowering or antioxidant treatment during pregnancy influence in utero programming and postnatal susceptibility to atherogenesis | Q34805411 | ||
| Effect of cerivastatin sodium, a new inhibitor of HMG-CoA reductase, on plasma lipid levels, progression of atherosclerosis, and the lesional composition in the plaques of WHHL rabbits | Q35041057 | ||
| Statin effects beyond lipid lowering--are they clinically relevant? | Q35067974 | ||
| Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat | Q35762325 | ||
| Rosuvastatin reduces experimental left ventricular infarct size after ischemia-reperfusion injury but not total coronary occlusion | Q45162560 | ||
| Effects of HMG-CoA reductase inhibition on hepatic expression of key cholesterol-regulatory enzymes and receptors in nephrotic syndrome | Q45176893 | ||
| Beneficial effect of simvastatin and pravastatin treatment on adverse cardiac remodelling and glomeruli loss in spontaneously hypertensive rats | Q45194895 | ||
| Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic mice | Q45234516 | ||
| Pravastatin modulates early diabetic nephropathy in an experimental model of diabetic renal disease | Q45244106 | ||
| Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress | Q45251438 | ||
| The changes in the endothelial expression of cell adhesion molecules and iNOS in the vessel wall after the short-term administration of simvastatin in rabbit model of atherosclerosis. | Q45273763 | ||
| Effects of Etidronate and Lovastatin on the Regression of Atherosclerosis in Cholesterol-Fed Rabbits | Q45964984 | ||
| Pitavastatin prevents intestinal ischemia/reperfusion-induced bacterial translocation and lung injury in atherosclerotic rats with hypoadiponectinemia | Q46046375 | ||
| Effect of atorvastatin on expression of IL-10 and TNF-alpha mRNA in myocardial ischemia-reperfusion injury in rats | Q46093260 | ||
| Statin treatment reduces glomerular inflammation and podocyte damage in rat deoxycorticosterone-acetate-salt hypertension | Q46117480 | ||
| Lovastatin prevents the impairment of endothelium dependent relaxation and inhibits accumulation of cholesterol in the aorta in experimental atherosclerosis in rabbits | Q46320467 | ||
| Effects of atorvastatin on calcium-regulating proteins: a possible mechanism to repair cardiac dysfunction in spontaneously hypertensive rats | Q46330759 | ||
| Effects of rosuvastatin on cardiovascular morphology and function in an ApoE-knockout mouse model of atherosclerosis | Q46368325 | ||
| HMG-CoA reductase inhibitor protects against in vivo arterial thrombosis by augmenting platelet-derived nitric oxide release in rats | Q46384803 | ||
| Evaluation cardioprotective effects of atorvastatin in rats by real time myocardial contrast echocardiography | Q46389703 | ||
| Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment | Q46395823 | ||
| Potential role of angiotensin-converting enzyme inhibitors and statins on early podocyte damage in a model of type 2 diabetes mellitus, obesity, and mild hypertension. | Q46438593 | ||
| Effect of pravastatin sodium, a new inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on very-low-density lipoprotein composition and kinetics in hyperlipidemia associated with experimental nephrosis | Q46452931 | ||
| Simvastatin regulates myocardial cytokine expression and improves ventricular remodeling in rats after acute myocardial infarction | Q46481866 | ||
| Emodin promotes atherosclerotic plaque stability in fat-fed apolipoprotein E-deficient mice | Q46570330 | ||
| Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan | Q46590668 | ||
| Combined simvastatin-manidipine protect against ischemia-reperfusion injury in isolated hearts from normocholesterolemic rats | Q46621976 | ||
| Fluvastatin decreases cardiac fibrosis possibly through regulation of TGF-beta(1)/Smad 7 expression in the spontaneously hypertensive rats | Q46631656 | ||
| Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetes | Q46649543 | ||
| Combined effects of HMG-CoA-reductase inhibition and renin-angiotensin system blockade on experimental atherosclerosis | Q46663253 | ||
| LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin | Q46672925 | ||
| Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits | Q46686077 | ||
| Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure | Q46705363 | ||
| Caffeinated coffee blunts the myocardial protective effects of statins against ischemia-reperfusion injury in the rat. | Q46713017 | ||
| Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure. | Q46737446 | ||
| Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat. | Q46743802 | ||
| Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring | Q46744956 | ||
| Evolution and involution of atherosclerosis and its relationship with vascular reactivity in hypercholesterolemic rabbits | Q46786176 | ||
| Simvastatin reverses the hypertension of heterozygous mice lacking cystathionine beta-synthase and apolipoprotein A-I. | Q46788466 | ||
| MDOC and atorvastatin have potential antiinflammatory effects in vascular endothelium of apoE-/- mouse model of atherosclerosis | Q46818115 | ||
| Hyperbaric oxygen treatment augments the efficacy of cilazapril and simvastatin regimens in an experimental nephrotic syndrome model. | Q46823385 | ||
| Treatment of cardiovascular dysfunction associated with the metabolic syndrome and type 2 diabetes | Q46829066 | ||
| Macrophage infiltration, lectin-like oxidized-LDL receptor-1, and monocyte chemoattractant protein-1 are reduced by chronic HMG-CoA reductase inhibition | Q46877195 | ||
| 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid, an active principle of kimchi, inhibits development of atherosclerosis in rabbits | Q46899065 | ||
| Anti-atherosclerotic effect of amlodipine, alone and in combination with atorvastatin, in APOE*3-Leiden/hCRP transgenic mice | Q46902689 | ||
| Enhanced cardioprotection against ischemia-reperfusion injury with combining sildenafil with low-dose atorvastatin | Q46910494 | ||
| 2,3,4',5-Tetrahydroxystilbene-2-O-beta-D-glucoside suppresses matrix metalloproteinase expression and inflammation in atherosclerotic rats | Q46921380 | ||
| Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II induced cardiovascular remodeling and renal insufficiency | Q46925640 | ||
| Atorvastatin reduces plasminogen activator inhibitor-1 expression in adipose tissue of atherosclerotic rabbits | Q46968283 | ||
| Effects of immunomodulatory drugs on plasma inflammatory markers in a rabbit model of atherosclerosis | Q46973105 | ||
| Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake | Q46974153 | ||
| Pravastatin restored the infarct size-limiting effect of ischemic preconditioning blunted by hypercholesterolemia in the rabbit model of myocardial infarction | Q47252034 | ||
| Effects of rosuvastatin on glomerular capillary size-selectivity function in rats with renal mass ablation | Q47270697 | ||
| HMG-CoA reductase and ACAT inhibitors act synergistically to lower plasma cholesterol and limit atherosclerotic lesion development in the cholesterol-fed rabbit | Q47703113 | ||
| Effects of simvastatin and atorvastatin on inflammation markers in plasma | Q43959187 | ||
| Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis | Q43993724 | ||
| Postischemic acute renal failure is reduced by short-term statin treatment in a rat model | Q44111644 | ||
| Effect of atorvastatin on high-density lipoprotein apolipoprotein A-I production and clearance in the New Zealand white rabbit | Q44235654 | ||
| A 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor reduces hypertensive nephrosclerosis in stroke-prone spontaneously hypertensive rats | Q44243484 | ||
| Anti-thrombotic effects of atorvastatin--an effect unrelated to lipid lowering | Q44255221 | ||
| HMG-CoA reductase inhibitor has protective effects against stroke events in stroke-prone spontaneously hypertensive rats. | Q44269132 | ||
| Fluvastatin prevents renal dysfunction and vascular NO deficit in apolipoprotein E-deficient mice. | Q44316900 | ||
| Effects of amlodipine, atorvastatin and combination of both on advanced atherosclerotic plaque in APOE*3-Leiden transgenic mice | Q44353368 | ||
| Preventive effect of cerivastatin on diabetic nephropathy through suppression of glomerular macrophage recruitment in a rat model | Q44458242 | ||
| Simvastatin inhibits expression of tissue factor in advanced atherosclerotic lesions of apolipoprotein E deficient mice independently of lipid lowering: potential role of simvastatin-mediated inhibition of Egr-1 expression and activation | Q44485529 | ||
| Differential effects of amlodipine and atorvastatin treatment and their combination on atherosclerosis in ApoE*3-Leiden transgenic mice | Q44491764 | ||
| Synergistic effect of angiotensin-converting enzyme (ACE) and 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibition on inflammatory markers in atherosclerotic rabbits | Q44505146 | ||
| Hypolipidemic and anti-atherogenic effects of long-term Cholestin (Monascus purpureus-fermented rice, red yeast rice) in cholesterol fed rabbits | Q44520782 | ||
| Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin | Q44562028 | ||
| HMG-CoA reductase inhibitor, fluvastatin, has cholesterol-lowering independent "direct" effects on atherosclerotic vessels in high cholesterol diet-fed rabbits | Q44580461 | ||
| Beneficial pleiotropic vascular effects of rosuvastatin in two hypertensive models | Q44588111 | ||
| Pravastatin Prevents Arrhythmias Induced by Coronary Artery Ischemia/Reperfusion in Anesthetized Normocholesterolemic Rats | Q44591131 | ||
| Effects of pravastatin on cardiomyocyte hypertrophy and ventricular vulnerability in normolipidemic rats after myocardial infarction | Q44679149 | ||
| Fluvastatin treatment inhibits leucocyte adhesion and extravasation in models of complement-mediated acute inflammation. | Q44738348 | ||
| Anti-lipid deposition effect of HMG-CoA reductase inhibitor, pitavastatin, in a rat model of hypertension and hypercholesterolemia | Q44768231 | ||
| The selective peroxisomal proliferator-activated receptor-gamma agonist has an additive effect on plaque regression in combination with simvastatin in experimental atherosclerosis: in vivo study by high-resolution magnetic resonance imaging | Q44794456 | ||
| Simvastatin-induced myocardial protection against ischemia-reperfusion injury is mediated by activation of ATP-sensitive K+ channels | Q44939986 | ||
| Fluvastatin enhances the inhibitory effects of a selective AT1 receptor blocker, valsartan, on atherosclerosis | Q45081308 | ||
| Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase | Q45091743 | ||
| Effect of simvastatin on left ventricular mass in hypercholesterolemic rabbits | Q45107995 | ||
| HMG-CoA reductase inhibition reverses LCAT and LDL receptor deficiencies and improves HDL in rats with chronic renal failure | Q45126783 | ||
| Endothelial dysfunction and hypercontractility of vascular myocytes are ameliorated by fluvastatin in obese Zucker rats | Q45154726 | ||
| Developing core outcome sets for clinical trials: issues to consider | Q36320178 | ||
| Anti-inflammatory effects of statins: clinical evidence and basic mechanisms | Q36337932 | ||
| Effects of statins on renal function | Q36401924 | ||
| Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis | Q36656816 | ||
| Diabetes reduces aortic endothelial gap junctions in ApoE-deficient mice: simvastatin exacerbates the reduction | Q36744061 | ||
| Renoprotection by statins is linked to a decrease in renal oxidative stress, TGF-beta, and fibronectin with concomitant increase in nitric oxide bioavailability | Q36807095 | ||
| Simvastatin treatment ameliorates autoimmune disease associated with accelerated atherosclerosis in a murine lupus model | Q37362915 | ||
| Effects of simvastatin on cardiac neural and electrophysiologic remodeling in rabbits with hypercholesterolemia | Q37375910 | ||
| Pravastatin for the prevention of preeclampsia in high-risk pregnant women | Q37432893 | ||
| Statins and pregnancy: between supposed risks and theoretical benefits. | Q38000338 | ||
| Flaws in animal studies exploring statins and impact on meta-analysis. | Q38199145 | ||
| Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve | Q38261649 | ||
| Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor | Q38298319 | ||
| Suppression of established atherosclerosis and xanthomas in mature WHHL rabbits by keeping their serum cholesterol levels extremely low. Effect of pravastatin sodium in combination with cholestyramine | Q39258969 | ||
| Combination treatment with troglitazone, an insulin action enhancer, and pravastatin, an inhibitor of HMG-CoA reductase, shows a synergistic effect on atherosclerosis of WHHL rabbits | Q39487822 | ||
| Atorvastatin inhibits plaque development and adventitial neovascularization in ApoE deficient mice independent of plasma cholesterol levels | Q39624057 | ||
| Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy. | Q39802111 | ||
| HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway | Q39946864 | ||
| Pravastatin prevents myocardium from ischemia-induced fibrosis by protecting vascular endothelial cells exposed to oxidative stress | Q40242567 | ||
| Lovastatin ameliorates the development of glomerulosclerosis and uremia in experimental nephrotic syndrome | Q41896190 | ||
| Reduction of infarct size by short-term pretreatment with atorvastatin | Q42171570 | ||
| Influence of rosuvastatin on the NAD(P)H oxidase activity in the retina and electroretinographic response of spontaneously hypertensive rats. | Q42626090 | ||
| Translating animal research into clinical benefit | Q42981287 | ||
| Comparison of lycopene and fluvastatin effects on atherosclerosis induced by a high-fat diet in rabbits | Q43421261 | ||
| Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering | Q43516483 | ||
| Simvastatin inhibits sPLA2 IIa expression in aorta and myocardium | Q43602259 | ||
| Rosuvastatin given during reperfusion decreases infarct size and inhibits matrix metalloproteinase-2 activity in normocholesterolemic and hypercholesterolemic rabbits | Q43607311 | ||
| Atorvastatin prevents glomerulosclerosis and renal endothelial dysfunction in hypercholesterolaemic rabbits. | Q43615536 | ||
| Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice. | Q43624004 | ||
| HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species | Q43641701 | ||
| Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins | Q43654200 | ||
| The combined effect of inhibiting both ACAT and HMG-CoA reductase may directly induce atherosclerotic lesion regression | Q43654205 | ||
| Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis | Q43726344 | ||
| Raman spectroscopic evaluation of the effects of diet and lipid-lowering therapy on atherosclerotic plaque development in mice | Q43764599 | ||
| Effects of atorvastatin on expression of ICAM-1 in atherosclerotic rabbits | Q43771042 | ||
| Simvastatin and atorvastatin enhance hypotensive effect of diltiazem in rats | Q43776542 | ||
| Impaired endothelium-dependent vasodilation in type 2 diabetes mellitus and the lack of effect of simvastatin | Q43782725 | ||
| Naringin has an antiatherogenic effect with the inhibition of intercellular adhesion molecule-1 in hypercholesterolemic rabbits | Q43798821 | ||
| Early benefits of pravastatin to experimentally induced atherosclerosis | Q43893723 | ||
| Simvastatin improves endothelial function in spontaneously hypertensive rats through a superoxide dismutase mediated antioxidant effect. | Q43903399 | ||
| P433 | issue | 9 | |
| P304 | page(s) | 848-871 | |
| P577 | publication date | 2014-09-01 | |
| P1433 | published in | European Journal of Clinical Investigation | Q15745208 |
| P1476 | title | Most appropriate animal models to study the efficacy of statins: a systematic review | |
| P478 | volume | 44 |
| Q64116903 | Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis |
| Q36345009 | Improving reproducibility and external validity. The role of standardization and data reporting of laboratory rat husbandry and housing |
| Q48194283 | Inhibition of mevalonate pathway prevents ischemia-induced cardiac dysfunction in rats via RhoA-independent signaling pathway. |
| Q37462636 | Lovastatin fails to improve motor performance and survival in methyl-CpG-binding protein2-null mice |
| Q42070460 | Statin Therapy Alters Lipid Storage in Diabetic Skeletal Muscle |
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