Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses

scientific article

Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1089/HUM.2014.092
P8608Fatcat IDrelease_k7uer3opovfrbaddtiwi6xsmhu
P932PMC publication ID4180303
P698PubMed publication ID25141764
P5875ResearchGate publication ID264990058

P50authorRob C HoebenQ47504188
P2093author name stringMartine L M Lamfers
Victor W van Beusechem
Zineb Belcaid
P2860cites workNewcastle disease virus-induced apoptosis in PC12 pheochromocytoma cellsQ44502787
Oncolytic viruses as therapeutic cancer vaccinesQ21245758
Adenosine deaminase: characterization and expression of a gene with a remarkable promoterQ24555814
Molecular mechanisms of T cell co-stimulation and co-inhibitionQ26864888
PAMPs and DAMPs: signal 0s that spur autophagy and immunityQ27004190
Nivolumab plus ipilimumab in advanced melanomaQ27852310
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
The blockade of immune checkpoints in cancer immunotherapyQ27860852
Autophagic cell death: the story of a misnomerQ29614564
Targeting tumor vasculature with an oncolytic virusQ30500348
Infection with oncolytic herpes simplex virus-1 induces apoptosis in neighboring human cancer cells: a potential target to increase anticancer activityQ33202718
Human adenovirus type 35 vector for gene therapy of brain cancer: improved transduction and bypass of pre-existing anti-vector immunity in cancer patients.Q33262597
An oncolytic adenovirus redirected with a tumor-specific T-cell receptorQ33308470
Directed evolution generates a novel oncolytic virus for the treatment of colon cancerQ33344440
Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trialQ33379689
Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imagingQ33641230
The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunityQ33670728
Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirusQ33690982
Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapyQ33933665
Anatomical differences determine distribution of adenovirus after convection-enhanced delivery to the rat brainQ34055421
Locally-delivered T-cell-derived cellular vehicles efficiently track and deliver adenovirus delta24-RGD to infiltrating gliomaQ34102273
Oncolytic viral therapy for prostate cancer: efficacy of reovirus as a biological therapeuticQ34103007
Conditionally replicative adenovirus with tropism expanded towards integrins inhibits osteosarcoma tumor growth in vitro and in vivoQ34291201
Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells.Q34313965
Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cellsQ44899739
Who's afraid of replication-competent adenoviruses?Q45102958
Measles virus vaccine-infected tumor cells induce tumor antigen cross-presentation by human plasmacytoid dendritic cellsQ45110054
Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virusQ45745964
Conditionally replicative adenovirus expressing p53 exhibits enhanced oncolytic potency.Q45856129
Increased glia-specific transgene expression with glial fibrillary acidic protein promoters containing multiple enhancer elementsQ45856304
A conditionally replicating adenovirus with strict selectivity in killing cells expressing epidermal growth factor receptor.Q45864653
Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumorsQ45869203
Recombinant adenoviral vectors have adjuvant activity and stimulate T cell responses against tumor cellsQ45870684
Bone marrow gene transfer in three patients with adenosine deaminase deficiency.Q45879021
Lymphocyte gene therapyQ45881517
Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibodyQ45882951
An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agentsQ45885443
Antiviral and antitumor T-cell immunity in patients treated with GM-CSF-coding oncolytic adenovirusQ45885739
The targeted oncolytic poxvirus JX-594 demonstrates antitumoral, antivascular, and anti-HBV activities in patients with hepatocellular carcinomaQ46364445
Homing properties of adipose-derived stem cells to intracerebral glioma and the effects of adenovirus infectionQ48888957
Potent antitumor immunity generated by a CD40-targeted adenoviral vaccineQ50064816
Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunityQ57541531
Adenovirus DNA replicationQ64378704
Vitamin D3-inducible mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growthQ64379255
Immunization with interleukin-2 transfected melanoma cells. A phase I-II study in patients with metastatic melanomaQ72850896
Reovirus Virotherapy Overrides Tumor Antigen Presentation Evasion and Promotes Protective Antitumor ImmunityQ82067713
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanomaQ84834335
Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanomaQ84906858
Activation of the human immune system via toll-like receptors by the oncolytic parvovirus H-1Q85435790
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancerQ34327051
Isolation of reovirus T3D mutants capable of infecting human tumor cells independent of junction adhesion molecule-A.Q34460916
Immunosuppression promotes reovirus therapy of colorectal liver metastasesQ34502982
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor.Q34583808
Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trialQ34759406
Directing systemic oncolytic viral delivery to tumors via carrier cellsQ35029126
Human adenovirus type 5 induces cell lysis through autophagy and autophagy-triggered caspase activityQ35076737
Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunityQ35155049
A transductionally retargeted adenoviral vector for virotherapy of Her2/neu-expressing prostate cancerQ35678429
Life after death: targeting high mobility group box 1 in emergent cancer therapiesQ36562901
Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulationQ36673709
Gene therapy in The Netherlands: highlights from the Low CountriesQ36920198
Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenicQ36931431
Trial watch: Oncolytic viruses for cancer therapyQ37028023
Requirement of an integrated immune response for successful neuroattenuated HSV-1 therapy in an intracranial metastatic melanoma modelQ37141874
Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cellsQ37157961
Cell death in the host response to infectionQ37195729
Immunogenic cancer cell death: a key-lock paradigmQ37198125
Tumor infection by oncolytic reovirus primes adaptive antitumor immunityQ37239555
Coronavirus genetically redirected to the epidermal growth factor receptor exhibits effective antitumor activity against a malignant glioblastomaQ37256658
Replacement of native adenovirus receptor-binding sites with a new attachment moiety diminishes hepatic tropism and enhances bioavailability in miceQ37330624
Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptorQ37336713
Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomasQ37461117
Cytoplasmic functions of the tumour suppressor p53.Q37466228
Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: low seroprevalence and non-cross-reactivity with Ad5.Q37596543
Innate immunity to adenovirusQ37718852
Fusogenic oncolytic herpes simplex viruses as a potent and personalized cancer vaccineQ37899222
Chapter four--Design of improved oncolytic adenovirusesQ38047473
Oncolytic virotherapy and immunogenic cancer cell death: sharpening the sword for improved cancer treatment strategiesQ38139255
Evolution of oncolytic viruses: novel strategies for cancer treatmentQ38159802
Viral warfare! Front-line defence and arming the immune system against cancer using oncolytic vaccinia and other viruses.Q38185772
Imaging preclinical tumour models: improving translational powerQ38221430
Oncolytic and immunotherapeutic vaccinia induces antibody-mediated complement-dependent cancer cell lysis in humansQ38450392
Mammalian orthoreovirus T3D infects U-118 MG cell spheroids independent of junction adhesion molecule-A.Q39003421
Preclinical safety assessment of Ad[I/PPT-E1A], a novel oncolytic adenovirus for prostate cancerQ39013607
Different responses of human pancreatic adenocarcinoma cell lines to oncolytic Newcastle disease virus infectionQ39037822
Heterogeneous reovirus susceptibility in human glioblastoma stem-like cell cultures.Q39116798
Reovirus modulates autophagy during oncolysis of multiple myelomaQ39209865
Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirusQ39384127
Measles virus causes immunogenic cell death in human melanoma.Q39428453
The chicken chorioallantoic membrane tumor assay as model for qualitative testing of oncolytic adenovirusesQ39455183
A cathepsin-cleavage site between the adenovirus capsid protein IX and a tumor-targeting ligand improves targeted transduction.Q39455900
Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune primingQ39588655
Directed adenovirus evolution using engineered mutator viral polymerasesQ39622784
Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolishedQ39682744
The HSV-2 mutant DeltaPK induces melanoma oncolysis through nonredundant death programs and associated with autophagy and pyroptosis proteins.Q39792514
Sensitization to apoptosis underlies KrasD12-dependent oncolysis of murine C26 colorectal carcinoma cells by reovirus T3D.Q39798367
Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanomaQ39874999
Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses.Q39887869
Fiber-chimeric adenoviruses expressing fibers from serotype 16 and 50 improve gene transfer to human pancreatic adenocarcinomaQ39889523
Bioselection of a gain of function mutation that enhances adenovirus 5 release and improves its antitumoral potency.Q39923110
Recombinant vesicular stomatitis virus targeted to Her2/neu combined with anti-CTLA4 antibody eliminates implanted mammary tumorsQ39957477
A strategy for genetic modification of the spike-encoding segment of human reovirus T3D for reovirus targeting.Q39957922
Virotherapy of ovarian cancer with polymer-cloaked adenovirus retargeted to the epidermal growth factor receptor.Q40036993
Virus-mediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulationQ40056582
Conditionally replicating adenoviruses kill tumor cells via a basic apoptotic machinery-independent mechanism that resembles necrosis-like programmed cell deathQ40277603
Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirusQ40284343
Genetic targeting of adenovirus vectors using a reovirus sigma1-based attachment proteinQ40309058
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.Q40360926
Oncolytic adenovirus expressing a p53 variant resistant to degradation by HPV E6 protein exhibits potent and selective replication in cervical cancer.Q40387611
Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24.Q40454824
Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant gliomaQ40525035
Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IXQ40579221
Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors.Q40628834
Therapeutic efficacy of G207, a conditionally replicating herpes simplex virus type 1 mutant, for gallbladder carcinoma in immunocompetent hamstersQ40810220
Recombinant adenovirus vectors with knobless fibers for targeted gene transferQ40906930
The Nogo receptor NgR1 mediates infection by mammalian reovirus.Q42210794
Pre-clinical safety assessment of Ad[I/PPT-E1A], a novel oncolytic adenovirus for prostate cancerQ42236448
Antitumoural immunity by virus-mediated immunogenic apoptosis inhibits metastatic growth of hepatocellular carcinomaQ42950209
A measles virus vaccine strain derivative as a novel oncolytic agent against breast cancerQ43666519
Midkine and cyclooxygenase-2 promoters are promising for adenoviral vector gene delivery of pancreatic carcinomaQ43848150
Role of the immune response during neuro-attenuated herpes simplex virus-mediated tumor destruction in a murine intracranial melanoma model.Q43933421
Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.Q44183106
The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitroQ44200179
P433issue10
P921main subjectoncolytic virusQ1560099
virologyQ7215
P304page(s)875-884
P577publication date2014-09-17
P1433published inHuman Gene TherapyQ15757580
P1476titleChanging faces in virology: the dutch shift from oncogenic to oncolytic viruses
P478volume25

Reverse relations

Q97543035Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapycites workP2860

Search more.