| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Lianfeng Zhang | |
| Xingxu Huang | |||
| Yuanwu Ma | |||
| P2860 | cites work | RNA-guided human genome engineering via Cas9 | Q24598394 |
| Heritable genome editing in C. elegans via a CRISPR-Cas9 system | Q24601099 | ||
| Multiplex genome engineering using CRISPR/Cas systems | Q24609428 | ||
| Efficient genome editing in zebrafish using a CRISPR-Cas system | Q24610828 | ||
| High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity | Q37196274 | ||
| Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system | Q37214501 | ||
| Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases | Q37420329 | ||
| Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. | Q37420333 | ||
| One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering | Q37651840 | ||
| A guide to genome engineering with programmable nucleases | Q38201212 | ||
| Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. | Q39028341 | ||
| Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9. | Q42055857 | ||
| One-step generation of different immunodeficient mice with multiple gene modifications by CRISPR/Cas9 mediated genome engineering | Q42253638 | ||
| Effective gene targeting in rabbits using RNA-guided Cas9 nucleases. | Q42359465 | ||
| One-step generation of knockout pigs by zygote injection of CRISPR/Cas system | Q42419006 | ||
| Generating rats with conditional alleles using CRISPR/Cas9. | Q42762266 | ||
| The CRISPR/Cas system mediates efficient genome engineering in Bombyx mori. | Q42853658 | ||
| Generation of gene-modified mice via Cas9/RNA-mediated gene targeting | Q43179830 | ||
| Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease | Q43872258 | ||
| Targeted genome modification of crop plants using a CRISPR-Cas system. | Q47822803 | ||
| Heritable gene targeting in the mouse and rat using a CRISPR-Cas system. | Q47822814 | ||
| Generation of eGFP and Cre knockin rats by CRISPR/Cas9. | Q50452759 | ||
| Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. | Q52422824 | ||
| Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. | Q52422958 | ||
| CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes | Q24625361 | ||
| RNA-guided editing of bacterial genomes using CRISPR-Cas systems | Q24630389 | ||
| Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems | Q24633670 | ||
| A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity | Q24669850 | ||
| Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation | Q27681624 | ||
| Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA | Q27681727 | ||
| RNA-programmed genome editing in human cells | Q28044562 | ||
| Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease | Q28284509 | ||
| RNA-guided gene activation by CRISPR-Cas9-based transcription factors | Q28295458 | ||
| Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients | Q28303521 | ||
| Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification | Q29029259 | ||
| One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering | Q29547524 | ||
| CRISPR-Cas systems for editing, regulating and targeting genomes | Q29615781 | ||
| Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system | Q29615782 | ||
| CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering | Q29615783 | ||
| Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity | Q29615792 | ||
| DNA targeting specificity of RNA-guided Cas9 nucleases | Q29615793 | ||
| Improving CRISPR-Cas nuclease specificity using truncated guide RNAs | Q29616043 | ||
| Genome-scale CRISPR-Cas9 knockout screening in human cells | Q29616044 | ||
| High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells | Q29616045 | ||
| CRISPR RNA-guided activation of endogenous human genes | Q29617072 | ||
| Genetic screens in human cells using the CRISPR-Cas9 system | Q29617411 | ||
| Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis | Q30409270 | ||
| CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences | Q33791286 | ||
| CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing | Q33860682 | ||
| Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing | Q33875102 | ||
| Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. | Q34040385 | ||
| GT-Scan: identifying unique genomic targets | Q34136933 | ||
| Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice | Q34368220 | ||
| Locus-specific editing of histone modifications at endogenous enhancers | Q34369340 | ||
| Correction of a genetic disease in mouse via use of CRISPR-Cas9. | Q34658184 | ||
| Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library | Q35096218 | ||
| Heritable multiplex genetic engineering in rats using CRISPR/Cas9. | Q35112105 | ||
| Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos | Q36739960 | ||
| Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. | Q37022952 | ||
| Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. | Q37080386 | ||
| Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system | Q37117695 | ||
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CRISPR | Q412563 |
| Cas9 | Q16965677 | ||
| CRISPR-Cas method | Q17310682 | ||
| P304 | page(s) | 5186-5193 | |
| P577 | publication date | 2014-11-07 | |
| P1433 | published in | FEBS Journal | Q1388041 |
| P1476 | title | Genome modification by CRISPR/Cas9. | |
| P478 | volume | 281 |
| Q47547794 | 50 years of The FEBS Journal: looking back as well as ahead. |
| Q89076163 | A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression |
| Q38616274 | A simple method based on Sanger sequencing and MS Word wildcard searching to identify Cas9-induced frameshift mutations |
| Q54984258 | Abnormalities of hair structure and skin histology derived from CRISPR/Cas9-based knockout of phospholipase C-delta 1 in mice. |
| Q40142907 | Adeno-Associated Virus (AAV) gene therapy for cystic fibrosis: current barriers and recent developments |
| Q92239450 | Anticipating Emerging Biotechnology Threats: A case study of CRISPR |
| Q38670939 | CRISPR-Cas9 for medical genetic screens: applications and future perspectives |
| Q28079519 | CRISPR-Cas9: Tool for Qualitative and Quantitative Plant Genome Editing |
| Q92260833 | CRISPR-mediated gene editing to rescue haploinsufficient obesity syndrome |
| Q50972002 | CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH. |
| Q56610090 | Delivering CRISPR: a review of the challenges and approaches |
| Q94538325 | Epithelial cell -derived microvesicles: A safe delivery platform of CRISPR/Cas9 conferring synergistic anti-tumor effect with sorafenib |
| Q104471992 | Gene editing and RNAi approaches for COVID-19 diagnostics and therapeutics |
| Q98178387 | Generation of Gene-Knockout Mongolian Gerbils via CRISPR/Cas9 System |
| Q38817680 | Genome editing in nonhuman primates: approach to generating human disease models |
| Q38667415 | Harnessing Type I and Type III CRISPR-Cas systems for genome editing |
| Q37692030 | How to Train a Cell-Cutting-Edge Molecular Tools |
| Q92669848 | Human germline genome editing is illegal in Canada, but could it be desirable for some members of the rare disease community? |
| Q26779242 | Human microbiomes and their roles in dysbiosis, common diseases, and novel therapeutic approaches |
| Q36469682 | Linking DNA polymerase theta structure and function in health and disease |
| Q95272150 | Nanoparticle-Based Immunoengineered Approaches for Combating HIV |
| Q49795063 | New and emerging uses of CRISPR/Cas9 to genetically manipulate apicomplexan parasites |
| Q36347532 | Nutritional Control of Insect Reproduction |
| Q36957379 | PML plays both inimical and beneficial roles in HSV-1 replication |
| Q50248096 | Pre-organized Guide RNA in the Cas9 Complex Is Ready for the Selection of Target Double-Stranded DNA. |
| Q92648250 | Preclinical septic shock research: why we need an animal ICU |
| Q36249634 | Preliminary Characterization of a Leptin Receptor Knockout Rat Created by CRISPR/Cas9 System |
| Q52408012 | Science and Bioethics of CRISPR-Cas9 Gene Editing: An Analysis Towards Separating Facts and Fiction. |
| Q98613439 | Spermatogenesis is normal in Tex33 knockout mice |
| Q37234547 | TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs |
| Q58705745 | The Enhancement of Plant Disease Resistance Using CRISPR/Cas9 Technology |
| Q36937205 | The MYC 3' Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells |
| Q64276836 | The first genetically gene-edited babies: It's "irresponsible and too early" |
| Q39063181 | Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation |
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