Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs

scientific article

Functionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BMC.2011.07.018
P932PMC publication ID3162138
P698PubMed publication ID21807524
P5875ResearchGate publication ID51538736

P2093author name stringRonald Micura
Jessica Steger
P2860cites workInsights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosomeQ24647686
A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunitsQ27637633
Insights into Translational Termination from the Structure of RF2 Bound to the RibosomeQ27652801
Structures of the ribosome in intermediate states of ratchetingQ27657107
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational StateQ27657797
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolutionQ27665394
Short peptides conferring resistance to macrolide antibioticsQ30730087
Let's see how tmRNA rescues a stuck ribosomeQ34337326
Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocationQ34720876
Small interfering RNAs and their chemical synthesisQ34803858
The ribosome through the looking glassQ35192980
Identification of two distinct hybrid state intermediates on the ribosomeQ36462728
Role of hybrid tRNA-binding states in ribosomal translocation.Q36756856
Rigid spin-labeled nucleoside C: a nonperturbing EPR probe of nucleic acid conformation.Q36935432
Macrolide mythsQ37274164
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopyQ41618424
An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination.Q41846673
Reliable semi-synthesis of hydrolysis-resistant 3'-peptidyl-tRNA conjugates containing genuine tRNA modifications.Q42395997
Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase centerQ42688854
Native chemical ligation in the synthesis of internally modified oligonucleotide-peptide conjugatesQ42996479
Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activationQ43116255
A practical route to 3'-amino-3'-deoxyadenosine derivatives and puromycin analoguesQ44331470
The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis.Q44910617
Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reactionQ46802328
Non-hydrolyzable RNA-peptide conjugates: a powerful advance in the synthesis of mimics for 3'-peptidyl tRNA terminiQ47935071
Unraveling the structure of the ribosome (Nobel Lecture).Q48307700
Polar bears, antibiotics, and the evolving ribosome (Nobel Lecture).Q48307712
From the structure and function of the ribosome to new antibiotics (Nobel Lecture).Q48307887
One SmpB molecule accompanies tmRNA during its passage through the ribosomes.Q54424278
Amphiphilic 3'-peptidyl-RNA conjugatesQ73589443
High-yield immobilization of a puromycin analogue for the solid support synthesis of aminoacyl-tRNA fragmentsQ73685607
Chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 SnRNA stem-loop segmentQ75343423
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectstyreneQ28917
P304page(s)5167-5174
P577publication date2011-07-19
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleFunctionalized polystyrene supports for solid-phase synthesis of glycyl-, alanyl-, and isoleucyl-RNA conjugates as hydrolysis-resistant mimics of peptidyl-tRNAs
P478volume19

Reverse relations

cites work (P2860)
Q47998651Conformational and chemical selection by a trans-acting editing domain.
Q46953989Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemX(Wv) aminoacyl transferase
Q64122808Flexizyme-catalyzed synthesis of 3'-aminoacyl-NH-tRNAs
Q45160993Molecular insights into protein synthesis with proline residues.
Q53817307Native Chemical Ligation of Hydrolysis-Resistant 3'-NH-Cysteine-Modified RNA.
Q42155357Selective desulfurization significantly expands sequence variety of 3'-peptidyl-tRNA mimics obtained by native chemical ligation
Q92936611Silica Surface Modification and Its Application in Permanent Link with Nucleic Acids
Q38302622Synthesis of aminoacylated N(6),N(6)-dimethyladenosine solid support for efficient access to hydrolysis-resistant 3'-charged tRNA mimics
Q33566326The synthesis of methylated, phosphorylated, and phosphonated 3'-aminoacyl-tRNA(Sec) mimics

Search more.