The transient receptor potential cation channel subfamily V member 6 (TRPV6): genetics, biochemical properties, and functions of exceptional calcium channel proteins

scientific article

The transient receptor potential cation channel subfamily V member 6 (TRPV6): genetics, biochemical properties, and functions of exceptional calcium channel proteins is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1139/BCB-2014-0063
P698PubMed publication ID25372600

P2093author name stringVeit Flockerzi
Christof Stoerger
P2860cites workIn vivo detection of human TRPV6-rich tumors with anti-cancer peptides derived from soricidinQ21133627
Population history and natural selection shape patterns of genetic variation in 132 genesQ21146407
Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancerQ24291019
The TRPV6 gene, cDNA and proteinQ48300393
Male fertility depends on Ca²+ absorption by TRPV6 in epididymal epithelia.Q51468303
Clinical chemistry reference database for Wistar rats and C57/BL6 mice.Q51752618
Ca2+ dependence of the Ca2+-selective TRPV6 channelQ24295269
The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUGQ24338946
Structure of the TRPV1 ion channel determined by electron cryo-microscopyQ27680759
TRPV1 structures in distinct conformations reveal activation mechanismsQ27680762
Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorptionQ28140902
Identification of evolutionarily conserved non-AUG-initiated N-terminal extensions in human coding sequencesQ28304019
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel geneQ28513722
Functional TRPV6 channels are crucial for transepithelial Ca2+ absorptionQ28592554
Na+/Ca2+-K+ exchangers (NCKX): functional properties and physiological rolesQ28629956
Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutationQ30514425
The single pore residue Asp542 determines Ca2+ permeation and Mg2+ block of the epithelial Ca2+ channel.Q31465646
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sitesQ33333147
TRPV6 alleles do not influence prostate cancer progressionQ33512614
Calcium-binding proteins: distribution and implication in mammalian placentaQ34176869
Disentangling the effects of demography and selection in human historyQ34346838
Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulinQ34756215
Calcium channels, transporters and exchangers in placenta: a reviewQ35947521
Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.Q36412396
Interplay between calmodulin and phosphatidylinositol 4,5-bisphosphate in Ca2+-induced inactivation of transient receptor potential vanilloid 6 channelsQ36635955
Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9kQ36692068
TRPV6 is not required for 1alpha,25-dihydroxyvitamin D3-induced intestinal calcium absorption in vivoQ37019007
Calcium and phosphate homeostasis: concerted interplay of new regulatorsQ37091865
The Na⁺/H⁺ exchanger isoform 3 is required for active paracellular and transcellular Ca²⁺ transport across murine cecumQ37123846
Uterine and placental expression of TRPV6 gene is regulated via progesterone receptor- or estrogen receptor-mediated pathways during pregnancy in rodentsQ37222092
A TRPC1 protein-dependent pathway regulates osteoclast formation and function.Q37311840
TRPV6 channelsQ38206430
Calcium channel TRPV6 expression in human duodenum: different relationships to the vitamin D system and aging in men and womenQ38435942
TRPV6 channel controls prostate cancer cell proliferation via Ca(2+)/NFAT-dependent pathways.Q40126939
Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation.Q40234410
Characterization of a Madin-Darby canine kidney cell line stably expressing TRPV5.Q40415526
Outer pore architecture of a Ca2+-selective TRP channelQ40596874
CaT1 expression correlates with tumor grade in prostate cancerQ40799864
The human TRPV6 channel protein is associated with cyclophilin B in human placentaQ44174397
The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice.Q46293365
Expression of the Ca2+-selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progressionQ47414682
Electrophysiologic characteristics of the Ca-permeable channels, ECaC and CaT, in the kidneyQ47842342
Molecular identification of the apical Ca2+ channel in 1, 25-dihydroxyvitamin D3-responsive epitheliaQ47978841
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)441-448
P577publication date2014-08-26
P1433published inBiochemistry and Cell BiologyQ4914719
P1476titleThe transient receptor potential cation channel subfamily V member 6 (TRPV6): genetics, biochemical properties, and functions of exceptional calcium channel proteins
P478volume92

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cites work (P2860)
Q37145029Coupling of TRPV6 and TMEM16A in epithelial principal cells of the rat epididymis
Q92383138TRPV6 as A Target for Cancer Therapy