Stem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects.

scientific article

Stem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FPHYS.2014.00419
P932PMC publication ID4212603
P698PubMed publication ID25400586
P5875ResearchGate publication ID268450716

P50authorRuben CoronelQ38643388
P2093author name stringNicoline W Smit
P2860cites workBasic Mechanisms of Cardiac Impulse Propagation and Associated ArrhythmiasQ22337019
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Human mesenchymal stem cells make cardiac connexins and form functional gap junctionsQ24678071
Electrophysiological changes in heart failure and their implications for arrhythmogenesisQ26860429
Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytesQ28345594
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RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trialQ29620044
Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat heartsQ29620480
Paracrine mechanisms in adult stem cell signaling and therapyQ29620571
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Physiological Coupling of Donor and Host Cardiomyocytes After Cellular TransplantationQ31141231
Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitroQ33245884
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Phosphorylation of connexin43 on serine 306 regulates electrical couplingQ33577094
Gap junctions in cardiovascular diseaseQ33949000
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Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmiaQ59064296
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Slow conduction in the infarcted human heart. 'Zigzag' course of activationQ72885921
Nerve sprouting and sudden cardiac deathQ73675155
Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmicQ73764581
Cardiac connections--the antiarrhythmic solution?Q80959575
Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarctionQ81435055
Transmural dispersion of refractoriness and conduction velocity is associated with heterogeneously reduced connexin43 in a rabbit model of heart failureQ81732820
[The SCIPIO and CADUCEUS studies]Q85574350
Engraftment patterns of human adult mesenchymal stem cells expose electrotonic and paracrine proarrhythmic mechanisms in myocardial cell culturesQ86159146
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Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.Q34133412
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Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their hostQ35146911
Plasticity of adult stem cellsQ35684656
Pharmacology of gap junctions in the cardiovascular systemQ35749973
Role of gap junctions in the propagation of the cardiac action potentialQ35749980
Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonanceQ36252910
Biological pacemakers based on I(f).Q36880789
Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytesQ37302419
Characterizing functional stem cell-cardiomyocyte interactions.Q37657548
The pathophysiologic basis of fractionated and complex electrograms and the impact of recording techniques on their detection and interpretationQ37734722
Adipose-derived stem cells for myocardial infarctionQ37813497
Gene- and cell-based bio-artificial pacemaker: what basic and translational lessons have we learned?Q38016715
Induced pluripotent stem cell-derived cardiomyocytes: boutique science or valuable arrhythmia model?Q38097414
Intracoronary stem cell infusion after acute myocardial infarction: a meta-analysis and update on clinical trialsQ39222871
Impedance-based detection of beating rhythm and proarrhythmic effects of compounds on stem cell-derived cardiomyocytesQ39655954
Electromechanical integration of cardiomyocytes derived from human embryonic stem cells.Q40479961
Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational studyQ41574770
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured heartsQ41980314
Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43-positive gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in canine heart.Q43117219
Mesenchymal stem cell injection induces cardiac nerve sprouting and increased tenascin expression in a Swine model of myocardial infarctionQ44354468
Histological study on the distribution of autonomic nerves in the human heartQ44367419
Electrophysiological properties of human mesenchymal stem cellsQ44632042
Conduction slowing by the gap junctional uncoupler carbenoxoloneQ44653097
Quantification of spatial inhomogeneity in conduction and initiation of reentrant atrial arrhythmiasQ44942193
Cardiac electrical restitution properties and stability of reentrant spiral waves: a simulation study.Q45949020
Vulnerability to re-entry in simulated two-dimensional cardiac tissue: effects of electrical restitution and stimulation sequenceQ46339927
Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantationQ46564931
Differential connexin distribution accommodates cardiac function in different speciesQ46690042
Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiologic propertiesQ46799141
Human adult bone marrow mesenchymal stem cells repair experimental conduction block in rat cardiomyocyte cultures.Q46802493
Progressive increase in conduction velocity across human mesenchymal stem cells is mediated by enhanced electrical coupling.Q50716409
Effect of gap junction distribution on impulse propagation in a monolayer of myocytes: a model study.Q50852578
Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model.Q51228467
Skeletal myoblast transplantation: no MAGIC bullet for ischemic cardiomyopathy.Q53464494
Heart failureQ53998058
P304page(s)419
P577publication date2014-10-29
P1433published inFrontiers in PhysiologyQ2434141
P1476titleStem cells can form gap junctions with cardiac myocytes and exert pro-arrhythmic effects
P478volume5

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cites work (P2860)
Q48623367Antiarrhythmic effect of growth factor-supplemented cardiac progenitor cells in chronic infarcted heart.
Q48162551Biologically active constituents of the secretome of human W8B2+ cardiac stem cells.
Q47637334Biomechanical Regulation of Mesenchymal Stem Cells for Cardiovascular Tissue Engineering
Q39347586Concise Review: Criteria for Chamber-Specific Categorization of Human Cardiac Myocytes Derived from Pluripotent Stem Cells
Q47770967Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications
Q41422153Editorial: Cardiac electronic remodeling and susceptibility to arrhythmias: an introduction and brief historical overview
Q26781319Excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes
Q26779602Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes
Q34465590New therapies for reducing post-myocardial left ventricular remodeling
Q36098333Slow conduction in mixed cultured strands of primary ventricular cells and stem cell-derived cardiomyocytes
Q91790408The Role of Membrane Capacitance in Cardiac Impulse Conduction: An Optogenetic Study With Non-excitable Cells Coupled to Cardiomyocytes
Q90376503Turning regenerative technologies into treatment to repair myocardial injuries

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