Regulation and evasion of antiviral immune responses by porcine reproductive and respiratory syndrome virus.

scientific article published on 18 December 2014

Regulation and evasion of antiviral immune responses by porcine reproductive and respiratory syndrome virus. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/J.VIRUSRES.2014.12.014
P932PMC publication ID7132515
P698PubMed publication ID25529442

P50authorQiong ZhangQ85438941
P2093author name stringChen Huang
Wen-hai Feng
P2860cites workInterleukin-10 and the interleukin-10 receptorQ24290912
TAK1 is a ubiquitin-dependent kinase of MKK and IKKQ24291454
Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factorsQ24303448
Immune signaling by RIG-I-like receptorsQ24304438
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionQ24318426
Innate immune recognition of viral infectionQ24498364
Foot-and-mouth disease virus 3C protease induces cleavage of translation initiation factors eIF4A and eIF4G within infected cellsQ24524297
The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like proteinQ24562149
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathwayQ24563231
A diverse range of gene products are effectors of the type I interferon antiviral responseQ24626018
Virus attenuation by genome-scale changes in codon pair biasQ24644457
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Interferon-inducible antiviral effectorsQ27486790
Structure and cleavage specificity of the chymotrypsin-like serine protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)Q27656805
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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Q27861127
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The widespread regulation of microRNA biogenesis, function and decayQ28131796
VISA is an adapter protein required for virus-triggered IFN-beta signalingQ28131814
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chainQ28142613
miR-181a is an intrinsic modulator of T cell sensitivity and selectionQ28294631
Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophagesQ45394335
The nsp1alpha and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesisQ45397788
Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting abilityQ45411355
The primary GP5 neutralization epitope of North American isolates of porcine reproductive and respiratory syndrome virusQ45559394
Lymphoid tissue tropism of porcine reproductive and respiratory syndrome virus replication during persistent infection of pigs originally exposed to virus in uteroQ45710797
Upregulation of interleukin-10 gene expression in the leukocytes of pigs infected with porcine reproductive and respiratory syndrome virusQ45718490
Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokinesQ45723087
Porcine reproductive and respiratory syndrome (PRRS) virus down-modulates TNF-alpha production in infected macrophagesQ45740651
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Clinical signs and economic losses caused by porcine reproductive and respiratory syndrome virus in a large breeding farmQ45761825
Porcine reproductive and respiratory syndrome virus: a persistent infectionQ45761836
Cell-Mediated Immunity to Porcine Reproductive and Respiratory Syndrome Virus in SwineQ45762042
Antibody-dependent enhancement (ADE) of porcine reproductive and respiratory syndrome virus (PRRSV) infection in pigsQ45769327
Endemic porcine reproductive and respiratory syndrome virus infection of nursery pigs in two swine herds without current reproductive failureQ45775961
Immune response and persistence of the porcine reproductive and respiratory syndrome virus in infected pigs and farm unitsQ45782721
Characterization of the Humoral Immune Response to Porcine Reproductive and Respiratory Syndrome (PRRS) Virus InfectionQ45788537
Serologic evidence incriminating a recently isolated virus (ATCC VR-2332) as the cause of swine infertility and respiratory syndrome (SIRS).Q45865413
Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulationQ45881575
Interleukin-10, interleukin-12, and interferon-gamma levels in the respiratory tract following mycoplasma hyopneumoniae and PRRSV infection in pigs.Q51646614
The molecular biology of arterivirusesQ56897174
Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune inductionQ56907798
Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signallingQ58435118
European genotype of porcine reproductive and respiratory syndrome (PRRSV) infects monocyte-derived dendritic cells but does not induce Treg cellsQ61473737
Analysis of cellular immune response in pigs recovered from porcine respiratory and reproductive syndrome infectionQ73026564
Nidovirales: a new order comprising Coronaviridae and ArteriviridaeQ73828706
Porcine reproductive and respiratory syndromeQ74450263
From vanilla to 28 flavors: multiple varieties of T regulatory cellsQ80141724
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-αQ84281957
Ligation of Fc gamma receptor IIB enhances levels of antiviral cytokine in response to PRRSV infection in vitroQ84538874
Parallel pathways of virus recognitionQ36484011
Porcine reproductive and respiratory syndrome virusQ36490646
Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responsesQ36559745
Apoptosis and caspases regulate death and inflammation in sepsisQ36622618
Innate immunity--cross-talk with adaptive immunity through pattern recognition receptors and cytokinesQ36678106
Natural regulatory T cells: mechanisms of suppressionQ36719995
MicroRNA in TLR signaling and endotoxin tolerance.Q36745742
Viruses, microRNAs, and host interactionsQ36753937
Porcine reproductive and respiratory syndrome virus Nsp1β inhibits interferon-activated JAK/STAT signal transduction by inducing karyopherin-α1 degradationQ36759930
Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cellsQ36820036
The challenge of PRRS immunology.Q36888431
Expression and Antibody Preparation of GP5a Gene of Porcine Reproductive and Respiratory Syndrome VirusQ36946374
Innate recognition of virusesQ36950601
Signalling pathways mediating type I interferon gene expression.Q36955426
Regulatory T cells and infection: a dangerous necessityQ36975739
An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181aQ37145975
microRNAs and the immune responseQ37178538
Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonucleaseQ37191844
MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancerQ37210788
The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosisQ37247956
Comparative analysis of apoptotic changes in peripheral immune organs and lungs following experimental infection of piglets with highly pathogenic and classical porcine reproductive and respiratory syndrome virus.Q37479756
The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acidsQ37495470
Potential role of porcine reproductive and respiratory syndrome virus structural protein GP2 in apoptosis inhibitionQ37543553
Differential host cell gene expression and regulation of cell cycle progression by nonstructural protein 11 of porcine reproductive and respiratory syndrome virusQ37639892
MicroRNA 155 regulates Japanese encephalitis virus-induced inflammatory response by targeting Src homology 2-containing inositol phosphatase 1.Q37714001
Novel strategies and approaches to develop the next generation of vaccines against porcine reproductive and respiratory syndrome virus (PRRSV).Q37775278
A brief review of CD163 and its role in PRRSV infectionQ37775280
The structural biology of PRRSVQ37778545
The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteinsQ37778881
Interferons and MicroRNAsQ37799601
Regulation and functions of the IL-10 family of cytokines in inflammation and diseaseQ37821924
MicroRNAs: the fine-tuners of Toll-like receptor signallingQ37844405
Decisions about dendritic cells: past, present, and futureQ37963951
MicroRNAs in inflammation and immune responsesQ37969887
Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infectionQ43047846
Induction of T helper 3 regulatory cells by dendritic cells infected with porcine reproductive and respiratory syndrome virusQ43543311
'Porcine reproductive and respiratory syndrome' in QuebecQ43660026
Serologic marker candidates identified among B-cell linear epitopes of Nsp2 and structural proteins of a North American strain of porcine reproductive and respiratory syndrome virus.Q43674601
Phenotypic and functional modulation of bone marrow-derived dendritic cells by porcine reproductive and respiratory syndrome virusQ44111791
Porcine reproductive and respiratory syndrome virus induces CD4+CD8+CD25+Foxp3+ regulatory T cells (Tregs).Q44453997
Interferon-alpha response to swine arterivirus (PoAV), the porcine reproductive and respiratory syndrome virusQ44489019
Detection of Foxp3 protein expression in porcine T lymphocytesQ44679147
Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virusQ44856331
A modified live PRRSV vaccine and the pathogenic parent strain induce regulatory T cells in pigs naturally infected with Mycoplasma hyopneumoniaeQ44962786
miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivoQ45095920
Porcine reproductive and respiratory syndrome virus infection activates IL-10 production through NF-κB and p38 MAPK pathways in porcine alveolar macrophagesQ45354246
Highly pathogenic porcine reproductive and respiratory syndrome virus impairs LPS- and poly(I:C)-stimulated tumor necrosis factor-alpha release by inhibiting ERK signaling pathwayQ45358370
Role of porcine reproductive and respiratory syndrome virus nucleocapsid protein in induction of interleukin-10 and regulatory T-lymphocytes (Treg).Q45358936
Immune responses in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virusQ45366240
Modulations of phenotype and cytokine expression of porcine bone marrow-derived dendritic cells by porcine reproductive and respiratory syndrome virusQ45387513
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNAQ28513215
Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNAQ28608975
Intrinsic antiviral immunityQ28709929
Mitochondria and cell death: outer membrane permeabilization and beyondQ29615459
The regulation of IL-10 production by immune cellsQ29615479
The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and deathQ29620519
Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmarkQ30362280
Live attenuated influenza virus vaccines by computer-aided rational designQ30390286
Identification of neutralizing and nonneutralizing epitopes in the porcine reproductive and respiratory syndrome virus GP5 ectodomain.Q30830088
Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccinesQ33294059
Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expressionQ33383235
Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylationQ33506618
Immunoregulatory properties of ISG15, an interferon-induced cytokineQ33610088
Innate immune evasion strategies of influenza virusesQ33646273
Transactivation of programmed ribosomal frameshifting by a viral proteinQ33694298
Coronaviruses post-SARS: update on replication and pathogenesisQ33694361
MiR-155 induction in microglial cells suppresses Japanese encephalitis virus replication and negatively modulates innate immune responses.Q33729909
Biochemical pathways of caspase activation during apoptosisQ33804316
The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signalingQ33855429
Virus-encoded proteinases and proteolytic processing in the Nidovirales.Q33867985
Ultrastructural pathogenesis of the PRRS virusQ33868845
A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniaeQ33889181
The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism functionsQ33964148
Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosisQ34102722
Porcine FcγRIIb mediates enhancement of porcine reproductive and respiratory syndrome virus (PRRSV) infectionQ34119043
Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1Q34142942
The level of virus-specific T-cell and macrophage recruitment in porcine reproductive and respiratory syndrome virus infection in pigs is independent of virus loadQ34151395
Biology of interleukin-10.Q34152272
Porcine reproductive and respiratory syndrome virus inhibits type I interferon signaling by blocking STAT1/STAT2 nuclear translocation.Q34190603
Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemiaQ34300055
Viruses and apoptosisQ34308884
The arterivirus nsp4 protease is the prototype of a novel group of chymotrypsin-like enzymes, the 3C-like serine proteasesQ34377519
In vitro and in vivo secretion of human ISG15, an IFN-induced immunomodulatory cytokine.Q34404800
MiR-125b reduces porcine reproductive and respiratory syndrome virus replication by negatively regulating the NF-κB pathwayQ34586343
Reactomes of porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virusQ34634889
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexesQ34671059
Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responsesQ34725292
North American porcine reproductive and respiratory syndrome viruses inhibit type I interferon production by plasmacytoid dendritic cellsQ34742827
MDA5/RIG-I and virus recognition.Q34749821
Hepatitis B virus X (HBx) play an anti-apoptosis role in hepatic progenitor cells by activating Wnt/β-catenin pathwayQ34915498
Porcine reproductive and respiratory syndrome virus nonstructural protein 4 induces apoptosis dependent on its 3C-like serine protease activityQ34919957
Cytokines and the lung.Q34976580
Attenuated influenza virus vaccines with modified NS1 proteinsQ35004207
Immunological responses of swine to porcine reproductive and respiratory syndrome virus infectionQ35039282
Characterization of the microRNAome in porcine reproductive and respiratory syndrome virus infected macrophagesQ35067677
IL-10, an inflammatory/inhibitory cytokine, but not always.Q35088038
Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cellsQ35203879
Lactate Dehydrogenase-Elevating Virus, Equine Arteritis Virus, and Simian Hemorrhagic Fever Virus: A New Group of Positive-Strand RNA VirusesQ35227715
Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiationQ35553324
Interferon-stimulated genes and their antiviral effector functionsQ35742006
Nonstructural protein 2 of porcine reproductive and respiratory syndrome virus inhibits the antiviral function of interferon-stimulated gene 15.Q35826847
Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein: identification of two papainlike cysteine proteasesQ35842089
A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKε.Q35885525
The interface between innate and adaptive immunityQ35904384
Role of neutralizing antibodies in PRRSV protective immunityQ35928806
DC infection promotes antiviral CTL priming: the 'Winkelried' strategyQ35998277
Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8+ T-cell differentiationQ36056393
Type I interferons (alpha/beta) in immunity and autoimmunityQ36072422
Porcine reproductive and respiratory syndrome virus nonstructural protein 2 contributes to NF-κB activationQ36235885
The role of CD4+CD25+ regulatory T cells in viral infectionsQ36242461
Suppression of immune responses in pigs by nonstructural protein 1 of porcine reproductive and respiratory syndrome virusQ36286619
Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus proteinQ36378336
CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease statusQ36399748
Interferon signalling network in innate defenceQ36471845
The JAK-STAT pathway at twentyQ38004201
Interferon-induced ISG15 pathway: an ongoing virus-host battleQ38082061
MicroRNAs as mediators of viral evasion of the immune systemQ38082296
miR-155: an ancient regulator of the immune systemQ38095500
Impact of PRRSV on activation and viability of antigen presenting cells.Q38167021
Overview: Replication of porcine reproductive and respiratory syndrome virusQ38175363
The amino acid at residue 155 in nonstructural protein 4 of porcine reproductive and respiratory syndrome virus contributes to its inhibitory effect for interferon-β transcription in vitroQ38986696
Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon.Q39021610
Involvement of unfolded protein response, p53 and Akt in modulation of porcine reproductive and respiratory syndrome virus-mediated JNK activationQ39126546
Porcine reproductive and respiratory syndrome virus induces pronounced immune modulatory responses at mucosal tissues in the parental vaccine strain VR2332 infected pigsQ39274756
Induction of interleukin-10 is dependent on p38 mitogen-activated protein kinase pathway in macrophages infected with porcine reproductive and respiratory syndrome virusQ39293871
Activation of c-Jun NH(2)-terminal kinase is required for porcine reproductive and respiratory syndrome virus-induced apoptosis but not for virus replicationQ39369941
CTLA4 mediated targeting enhances immunogenicity against PRRSV in a DNA prime/killed virus boost strategyQ39402779
Porcine reproductive and respiratory syndrome virus nucleocapsid protein modulates interferon-β production by inhibiting IRF3 activation in immortalized porcine alveolar macrophagesQ39468134
Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-β inductionQ39560719
Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory syndrome virusQ39654502
The cysteine protease domain of porcine reproductive and respiratory syndrome virus non-structural protein 2 antagonizes interferon regulatory factor 3 activationQ39657875
Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-κB and Sp1.Q39668646
Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cellsQ39711301
Identification of two auto-cleavage products of nonstructural protein 1 (nsp1) in porcine reproductive and respiratory syndrome virus infected cells: nsp1 function as interferon antagonistQ39763882
Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activationQ39773155
Acute phase response in porcine reproductive and respiratory syndrome virus infection.Q39920014
Colocalization and interaction of the porcine arterivirus nucleocapsid protein with the small nucleolar RNA-associated protein fibrillarinQ40133032
Recombinant swine beta interferon protects swine alveolar macrophages and MARC-145 cells from infection with Porcine reproductive and respiratory syndrome virusQ40166071
Induction of inducible CD4+CD25+Foxp3+ regulatory T lymphocytes by porcine reproductive and respiratory syndrome virus (PRRSV).Q40381618
Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United StatesQ40394450
Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of ChinaQ40439250
Porcine reproductive and respiratory syndrome: clinical disease, pathology and immunosuppressionQ40502040
Interferon type I response in porcine reproductive and respiratory syndrome virus-infected MARC-145 cellsQ40520755
Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virusQ40566308
Antibody production and blastogenic response in pigs experimentally infected with porcine reproductive and respiratory syndrome virus.Q40670052
IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.Q40674809
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta inductionQ40675827
An outbreak of porcine reproductive and respiratory syndrome in JapanQ40695488
The 3C protease activity of enterovirus 71 induces human neural cell apoptosisQ40745636
Epidemiology of porcine reproductive and respiratory syndrome (PRRS): an overviewQ40898280
The localization of porcine reproductive and respiratory syndrome virus nucleocapsid protein to the nucleolus of infected cells and identification of a potential nucleolar localization signal sequenceQ40926509
Kinetics of humoral immune response to the major structural proteins of the porcine reproductive and respiratory syndrome virusQ41252922
Apoptosis and disease: regulation and clinical relevance of programmed cell deathQ41360597
A modified serum neutralization test for the detection of antibody to porcine reproductive and respiratory syndrome virus in swine seraQ41458833
Mystery swine disease in the Netherlands: The isolation of Lelystad virusQ41677026
Equine arteritis virus gP5 protein induces apoptosis in cultured insect cellsQ42004778
Porcine reproductive and respiratory syndrome virus infects mature porcine dendritic cells and up-regulates interleukin-10 productionQ42071929
Porcine reproductive and respiratory syndrome virus nonstructural protein 4 antagonizes beta interferon expression by targeting the NF-κB essential modulatorQ42206807
MicroRNA-23 inhibits PRRSV replication by directly targeting PRRSV RNA and possibly by upregulating type I interferonsQ42238649
Computer-aided codon-pairs deoptimization of the major envelope GP5 gene attenuates porcine reproductive and respiratory syndrome virusQ42238661
Antibody-dependent enhancement of PRRSV infection down-modulates TNF-α and IFN-β transcription in macrophages.Q42245296
Phenotypic modulation and cytokine profiles of antigen presenting cells by European subtype 1 and 3 porcine reproductive and respiratory syndrome virus strains in vitro and in vivoQ42262846
MicroRNA-17~92 regulates effector and memory CD8 T-cell fates by modulating proliferation in response to infections.Q42266207
North American and European porcine reproductive and respiratory syndrome viruses differ in non-structural protein coding regionsQ42594875
P921main subjectporcine reproductive and respiratory syndrome virusQ1760147
porcine reproductive and respiratory syndromeQ2275037
P304page(s)101-111
P577publication date2014-12-18
2015-04-16
P1433published inVirus ResearchQ15749215
P1476titleRegulation and evasion of antiviral immune responses by porcine reproductive and respiratory syndrome virus
P478volume202

Reverse relations

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