Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex

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Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M707907200
P932PMC publication ID2186065
P698PubMed publication ID17993457

P50authorCraig E. CameronQ74809374
P2093author name stringYan Zhao
Harsh B Pathak
Jamie J Arnold
Zachary J Reitman
Miaoqing Shen
Qixin Wang
Ibrahim Moustafa
P2860cites workIdentification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPgQ24524070
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Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complexQ24681570
Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDproQ24812615
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Inhibition of poliovirus polymerase by guanidine in vitroQ27487053
The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf RNA and its interaction with the proteinase 3CQ27643129
Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA PolymeraseQ27643650
The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognitionQ27734773
Structure of the RNA-dependent RNA polymerase of poliovirusQ27744366
Refined X-ray crystallographic structure of the poliovirus 3C gene productQ27747494
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Scalable molecular dynamics with NAMDQ27860718
Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and BQ28145203
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Mutations in the poliovirus 3CD proteinase S1-specificity pocket affect substrate recognition and RNA bindingQ30423731
Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDproQ33780515
Poliovirus proteins induce membrane association of GTPase ADP-ribosylation factorQ33788730
Poliovirus 5'-terminal cloverleaf RNA is required in cis for VPg uridylylation and the initiation of negative-strand RNA synthesisQ33848778
Inhibition of poliovirus RNA synthesis by brefeldin AQ33930647
Utilization of a mammalian cell-based RNA binding assay to characterize the RNA binding properties of picornavirus 3C proteinases.Q34361291
Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C.Q34364212
Protein-primed RNA synthesis by purified poliovirus RNA polymeraseQ34470068
Poliovirus CRE-dependent VPg uridylylation is required for positive-strand RNA synthesis but not for negative-strand RNA synthesisQ34856873
Functional Dissection of a Poliovirus cis -Acting Replication Element [PV- cre (2C)]: Analysis of Single- and Dual- cre Viral Genomes and Proteins That Bind Specifically to PV- cre RNAQ34975487
Poliovirus cre (2C)-Dependent Synthesis of VPgpUpU Is Required for Positive- but Not Negative-Strand RNA SynthesisQ34976237
Genome-wide diversity and selective pressure in the human rhinovirusQ35844207
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication.Q35948087
Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complexQ36225116
Involvement of cellular membrane traffic proteins in poliovirus replicationQ36716351
High-resolution structure of a picornaviral internal cis-acting RNA replication element (cre).Q37494301
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymeraseQ37513764
Human rhinovirus-14 protease 3C (3Cpro) binds specifically to the 5'-noncoding region of the viral RNA. Evidence that 3Cpro has different domains for the RNA binding and proteolytic activitiesQ38313576
Poliovirus RNA synthesis utilizes an RNP complex formed around the 5'-end of viral RNA.Q38316546
Brefeldin A inhibits cell-free, de novo synthesis of poliovirusQ39579415
Genetic and biochemical studies of poliovirus cis-acting replication element cre in relation to VPg uridylylationQ39585311
Interactions of viral protein 3CD and poly(rC) binding protein with the 5' untranslated region of the poliovirus genomeQ39589554
Poliovirus requires a precise 5' end for efficient positive-strand RNA synthesisQ39591989
Biochemical and genetic studies of the initiation of human rhinovirus 2 RNA replication: identification of a cis-replicating element in the coding sequence of 2A(pro).Q39605080
Oligomeric structures of poliovirus polymerase are important for functionQ39714853
Interaction between the 5'-terminal cloverleaf and 3AB/3CDpro of poliovirus is essential for RNA replication.Q39870359
Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesisQ40038917
Purification and characterization of poliovirus polypeptide 3CD, a proteinase and a precursor for RNA polymeraseQ40062318
Mutational analysis of the proposed FG loop of poliovirus proteinase 3C identifies amino acids that are necessary for 3CD cleavage and might be determinants of a function distinct from proteolytic activityQ40067609
Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesisQ40339022
Hepatitis A virus proteinase 3C binding to viral RNA: correlation with substrate binding and enzyme dimerization.Q40516783
In vitro RNA binding of the hepatitis A virus proteinase 3C (HAV 3Cpro) to secondary structure elements within the 5' terminus of the HAV genome.Q41806897
Functional oligomerization of poliovirus RNA-dependent RNA polymeraseQ42256513
GRAMM-X public web server for protein-protein dockingQ42554377
Genetic evidence for an interaction between a picornaviral cis-acting RNA replication element and 3CD proteinQ42616826
Factors required for the Uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3Dpol) in vitroQ42847015
Poly (rC) binding protein 2 forms a ternary complex with the 5'-terminal sequences of poliovirus RNA and the viral 3CD proteinase.Q43206140
Secretory pathway function, but not cytoskeletal integrity, is required in poliovirus infection.Q43531485
Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation.Q44036981
Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli.Q44407927
Action of guanidine on the replication of poliovirus RNA.Q44419699
Site-directed mutagenesis of the putative catalytic triad of poliovirus 3C proteinaseQ44494180
A "slide-back" mechanism for the initiation of protein-primed RNA synthesis by the RNA polymerase of poliovirusQ44560683
Mutations at KFRDI and VGK domains of enterovirus 71 3C protease affect its RNA binding and proteolytic activitiesQ44765873
Dynamics of poliovirus-specific RNA synthesis and the effects of inhibitors of virus replicationQ45822625
Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primerQ46904333
Assays for poliovirus polymerase, 3D(Pol), and authentic RNA replication in HeLa S10 extracts.Q54596055
Sequence and structural determinants of the interaction between the 5'-noncoding region of picornavirus RNA and rhinovirus protease 3CQ72315781
Interaction of poliovirus polypeptide 3CDpro with the 5' and 3' termini of the poliovirus genome. Identification of viral and cellular cofactors needed for efficient bindingQ72724833
Visualization and functional analysis of RNA-dependent RNA polymerase latticesQ74335484
Significance of the C-terminal amino acid residue in mengovirus RNA-dependent RNA polymeraseQ80234105
P4510describes a project that usesImageQuantQ112270642
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectPoliovirusQ70923324
P304page(s)875-888
P577publication date2007-11-09
P1433published inJournal of Biological ChemistryQ867727
P1476titlePicornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex
P478volume283

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cites work (P2860)
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