DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hydrolysis: on the importance of not getting stuck

scientific article published on 14 August 2001

DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hydrolysis: on the importance of not getting stuck is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M105678200
P698PubMed publication ID11504729
P5875ResearchGate publication ID11839782

P2093author name stringSung P
Cox MM
Eggler AL
Rice KP
P2860cites workHuman Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitroQ24321787
Assessing the requirements for nucleotide excision repair proteins of Saccharomyces cerevisiae in an in vitro systemQ27930310
Characterization of Strand Exchange Activity of Yeast Rad51 ProteinQ27937121
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 proteinQ27937922
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinaseQ27938070
RecA-catalyzed, sequence-specific alkylation of DNA by cross-linking oligonucleotides. Effects of length and nonhomologous base substitutionsQ71185897
Sequence-specific covalent modification of DNA by cross-linking oligonucleotides. Catalysis by RecA and implication for the mechanism of synaptic joint formationQ71715603
Yeast Rad51 recombinase mediates polar DNA strand exchange in the absence of ATP hydrolysisQ71763096
Probing the structure of a putative intermediate in homologous recombination: the third strand in the parallel DNA triplex is in contact with the major groove of the duplexQ72171203
On the in vivo function of the RecA ATPaseQ78110027
Structural relationship of bacterial RecA proteins to recombination proteins from bacteriophage T4 and yeastQ28267407
A single-stranded DNA-binding protein is needed for efficient presynaptic complex formation by the Saccharomyces cerevisiae Rad51 proteinQ28647553
DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecAQ29622863
Basis for avid homologous DNA strand exchange by human Rad51 and RPA.Q30636828
Rad51 uses one mechanism to drive DNA strand exchange in both directionsQ30836821
Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in DNA strand exchangeQ33180095
RecA.oligonucleotide filaments bind in the minor groove of double-stranded DNA.Q33840414
Triplex DNA structures.Q34296747
DNA-strand exchange promoted by RecA protein in the absence of ATP: implications for the mechanism of energy transduction in protein-promoted nucleic acid transactionsQ34446753
recA protein of Escherichia coli promotes branch migration, a kinetically distinct phase of DNA strand exchangeQ35374701
Active nucleoprotein filaments of single-stranded binding protein and recA protein on single-stranded DNA have a regular repeating structureQ35848520
Activities of human recombination protein Rad51.Q35952348
Polarity of DNA strand exchange promoted by recombination proteins of the RecA familyQ36278034
Co-ordination of multiple DNA molecules in RecA fiber evidenced by linear dichroism spectroscopyQ37288294
Branch migration during Rad51-promoted strand exchange proceeds in either directionQ37470747
Ionic inhibition of formation of RecA nucleoprotein networks blocks homologous pairingQ37529416
Stable DNA heteroduplex formation catalyzed by the Escherichia coli RecA protein in the absence of ATP hydrolysisQ37655391
RecA protein promotes strand exchange with DNA substrates containing isoguanine and 5-methyl isocytosine.Q38309096
Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination proteinQ38316899
ATP hydrolysis and the displaced strand are two factors that determine the polarity of RecA-promoted DNA strand exchangeQ38326172
Human Rad51 protein can form homologous joints in the absence of net strand exchangeQ38329710
Interaction of the RecA protein of Escherichia coli with single-stranded oligodeoxyribonucleotides.Q38350546
The essential functions of human Rad51 are independent of ATP hydrolysisQ39448174
Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairingQ40387300
Structure of RecA-DNA complex and mechanism of DNA strand exchange reaction in homologous recombinationQ40502184
Why does RecA protein hydrolyse ATP?Q40682056
Quantitative analysis of the kinetics of end-dependent disassembly of RecA filaments from ssDNA.Q44082228
Studies on the biochemical basis of spontaneous mutation. II. The incorporation of a base and its analogue into DNA by wild-type, mutator and antimutator DNA polymerasesQ44705872
Binding of Rad51p to DNA. Interaction of Rad51p with single- and double-stranded DNA.Q46532694
The DNA binding properties of Saccharomyces cerevisiae Rad51 proteinQ46561573
DNA strand exchange promoted by RecA K72R. Two reaction phases with different Mg2+ requirementsQ47854190
On the Mechanism of RecA-Mediated Repair of Double-Strand Breaks: No Role for Four-Strand DNA Pairing IntermediatesQ47862748
A parallel DNA triplex as a model for the intermediate in homologous recombinationQ52375677
DNA strand exchange mediated by the Escherichia coli RecA protein initiates in the minor groove of double-stranded DNA.Q54567659
Evidence for the coupling of ATP hydrolysis to the final (extension) phase of RecA protein-mediated DNA strand exchangeQ54592049
Large-scale overproduction and rapid purification of the Escherichia coli ssb gene product. Expression of the ssb gene under lambda PL controlQ54785144
Similarity of the yeast RAD51 filament to the bacterial RecA filamentQ56937925
Role of RecA protein spiral filaments in genetic recombinationQ58028701
RecA protein-promoted homologous pairing and strand exchange between intact and partially single-stranded duplex DNAQ68052356
Characterization of the DNA binding activity of stable RecA-DNA complexes. Interaction between the two DNA binding sites within RecA helical filamentsQ68740732
Visualization of RecA-DNA complexes involved in consecutive stages of an in vitro strand exchange reactionQ70415899
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)38570-38581
P577publication date2001-08-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleDNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hydrolysis: on the importance of not getting stuck
P478volume276

Reverse relations

cites work (P2860)
Q38290716ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair
Q27640459ATP-mediated conformational changes in the RecA filament
Q77840676Bibliography. Current awareness on yeast
Q45198344Biochemical characterization of Borrelia burgdorferi's RecA protein
Q43882487Biochemical characterization of the human RAD51 protein. I. ATP hydrolysis
Q43882490Biochemical characterization of the human RAD51 protein. II. Adenosine nucleotide binding and competition
Q43882493Biochemical characterization of the human RAD51 protein. III. Modulation of DNA binding by adenosine nucleotides
Q27655595Conservation of a conformational switch in RadA recombinase fromMethanococcus maripaludis
Q45146779Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence
Q34976824Distinguishing characteristics of hyperrecombinogenic RecA protein from Pseudomonas aeruginosa acting in Escherichia coli
Q30488763Dynamics of RecA filaments on single-stranded DNA
Q60959760Evolution of cation binding in the active sites of P-loop nucleoside triphosphatases in relation to the basic catalytic mechanism
Q30857859Heteroduplex joint formation by a stoichiometric complex of Rad51 and Rad52 of Saccharomyces cerevisiae
Q33359391Homologous recombination properties of OsRad51, a recombinase from rice
Q27660441Insights into the mechanism of Rad51 recombinase from the structure and properties of a filament interface mutant
Q44321507Magnesium ion-dependent activation of the RecA protein involves the C terminus
Q39619300Molecular Modeling and Molecular Dynamics Simulations of Recombinase Rad51
Q34186972Physics of RecA-mediated homologous recognition
Q60917692Promotion of homology-directed DNA repair by polyamines
Q37041600Reversibility, equilibration, and fidelity of strand exchange reaction between short oligonucleotides promoted by RecA protein from escherichia coli and human Rad51 and Dmc1 proteins
Q38288580Role of ATP-binding motifs on DNA-binding activity and biological function of Rhp51, a Rad51 homologue in fission yeast
Q44309502Temperature dependence of HpRad51, the central protein of the homological recombination in the yeast Hansenula polymorpha
Q35550606The Bacterial RecA Protein as a Motor Protein
Q32186835The Rad51-dependent pairing of long DNA substrates is stabilized by replication protein A.
Q35209965The development and regulation of gene repair
Q37417028The differential extension in dsDNA bound to Rad51 filaments may play important roles in homology recognition and strand exchange.
Q44367835The herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) promotes strand invasion
Q35221357The rad51-K191R ATPase-defective mutant is impaired for presynaptic filament formation.
Q44881166hXRCC2 enhances ADP/ATP processing and strand exchange by hRAD51.
Q42853802pH-dependent activities and structural stability of loop-2-anchoring helix of RadA recombinase from Methanococcus voltae

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