Monitoring activity in neural circuits with genetically encoded indicators

scientific article published on 05 December 2014

Monitoring activity in neural circuits with genetically encoded indicators is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FNMOL.2014.00097
P932PMC publication ID4256991
P698PubMed publication ID25538558
P5875ResearchGate publication ID270004103

P50authorGerard Joseph BroussardQ64095804
P2093author name stringRuqiang Liang
Lin Tian
P2860cites workCircular permutation and receptor insertion within green fluorescent proteinsQ21045408
Genetically encoded green fluorescent Ca2+ indicators with improved detectability for neuronal Ca2+ signalsQ21133806
Large-scale recording of neuronal ensemblesQ22337229
Receptive fields of single neurones in the cat's striate cortexQ24537738
Cas9 as a versatile tool for engineering biologyQ24564294
Tight control of gene expression in mammalian cells by tetracycline-responsive promotersQ24564850
A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mappingQ24651191
Dynamic and quantitative Ca2+ measurements using improved cameleonsQ24652660
Functional fluorescent Ca2+ indicator proteins in transgenic mice under TET controlQ24793235
Mouse transgenic approaches in optogeneticsQ26863354
Targeting neurons and photons for optogeneticsQ27023926
Adaptive movement compensation for in vivo imaging of fast cellular dynamics within a moving tissueQ27340360
Optimization of a GCaMP Calcium Indicator for Neural Activity ImagingQ27674109
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogeneticsQ27676694
Structural basis of the ultrasensitive calcium indicator GCaMP6Q27688083
Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytesQ27688085
Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegansQ28140856
Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, AequoreaQ28189514
Targeting cells with single vectors using multiple-feature Boolean logicQ28241570
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulinQ28247685
High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensorQ34416562
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensorQ34419859
Detection in living cells of Ca2+-dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicatorsQ34425921
Fast nonnegative deconvolution for spike train inference from population calcium imagingQ34430465
A genetically encoded optical probe of membrane voltageQ34444696
Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes.Q34468652
Adeno-associated virus as a gene therapy vector: vector development, production and clinical applications.Q34506249
Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brainQ34530837
Activity-dependent scaling of quantal amplitude in neocortical neuronsQ28264163
Distributed hierarchical processing in the primate cerebral cortexQ28266250
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteinsQ28276992
Two-photon laser scanning fluorescence microscopyQ28280674
Genome editing with engineered zinc finger nucleasesQ28290795
Synaptic mechanisms underlying sparse coding of active touchQ28307881
Automatic identification of fluorescently labeled brain cells for rapid functional imagingQ28749185
Preface: Cerebral Cortex Has Come of AgeQ29543437
A high signal-to-noise Ca(2+) probe composed of a single green fluorescent proteinQ29616188
Ultrasensitive fluorescent proteins for imaging neuronal activityQ29616778
Deep tissue two-photon microscopyQ29619662
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicatorsQ29619969
Multiscale optical Ca2+ imaging of tonal organization in mouse auditory cortex.Q30404709
Imaging light responses of foveal ganglion cells in the living macaque eye.Q30426527
Monitoring synaptic and neuronal activity in 3D with synthetic and genetic indicators using a compact acousto-optic lens two-photon microscopeQ30443819
Fast GCaMPs for improved tracking of neuronal activityQ30447292
Simultaneous two-photon calcium imaging at different depths with spatiotemporal multiplexing.Q30474676
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2.Q30477207
Two-photon calcium imaging from head-fixed Drosophila during optomotor walking behaviorQ30477897
Identification and clustering of event patterns from in vivo multiphoton optical recordings of neuronal ensemblesQ30482952
SLM Microscopy: Scanless Two-Photon Imaging and Photostimulation with Spatial Light ModulatorsQ30485339
Radially expanding transglial calcium waves in the intact cerebellumQ30486303
Optical imaging of postsynaptic odor representation in the glomerular layer of the mouse olfactory bulbQ30489426
Visually evoked activity in cortical cells imaged in freely moving animalsQ30491438
Chronic cellular imaging of mouse visual cortex during operant behavior and passive viewingQ30494103
Functional imaging of hippocampal place cells at cellular resolution during virtual navigationQ30497210
Genetic visualization with an improved GCaMP calcium indicator reveals spatiotemporal activation of the spinal motor neurons in zebrafishQ30499293
Automated analysis of cellular signals from large-scale calcium imaging dataQ30505421
Activity in motor-sensory projections reveals distributed coding in somatosensationQ30524961
An expanded palette of genetically encoded Ca²⁺ indicatorsQ30533809
Long-term dynamics of CA1 hippocampal place codesQ30547047
Miniaturized integration of a fluorescence microscopeQ30555238
Genetically targeted optical electrophysiology in intact neural circuitsQ30560861
Concurrent activation of striatal direct and indirect pathways during action initiation.Q30579307
Natural neural projection dynamics underlying social behaviorQ30585970
Three fluorescent protein voltage sensors exhibit low plasma membrane expression in mammalian cellsQ34584596
Enhanced Archaerhodopsin Fluorescent Protein Voltage IndicatorsQ34806172
Development and characterization of a novel fluorescent indicator protein PMCA4-GCaMP2 in cardiomyocytes.Q34861125
A genetically encoded calcium indicator for chronic in vivo two-photon imagingQ34927345
Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brainQ35006292
A neuron-based screening platform for optimizing genetically-encoded calcium indicatorsQ35025522
Transgenic mice expressing a cameleon fluorescent Ca2+ indicator in astrocytes and Schwann cells allow study of glial cell Ca2+ signals in situ and in vivoQ35125143
Engineering and characterizing monomeric fluorescent proteins for live-cell imaging applications.Q35126438
Mapping brain activity at scale with cluster computingQ35214217
Quantitative comparison of genetically encoded Ca indicators in cortical pyramidal cells and cerebellar Purkinje cellsQ35238198
Modulation of visual responses by behavioral state in mouse visual cortexQ35247918
Concurrent imaging of synaptic vesicle recycling and calcium dynamicsQ35505880
Two-photon scanning microscopy of in vivo sensory responses of cortical neurons genetically encoded with a fluorescent voltage sensor in ratQ35846011
A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivoQ35861584
Building and breeding molecules to spy on cells and tumorsQ36024283
Imaging voltage in neuronsQ36071399
An amplified promoter system for targeted expression of calcium indicator proteins in the cerebellar cortexQ36128498
Glial calcium signaling and neuron-glia communication.Q36232523
Response of brain tissue to chronically implanted neural electrodesQ36273771
Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic modeQ36300120
Hybrid voltage sensor imaging of electrical activity from neurons in hippocampal slices from transgenic miceQ36531958
TALENs: a widely applicable technology for targeted genome editingQ36540717
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reportersQ36670320
Spatial gradients and multidimensional dynamics in a neural integrator circuitQ36759305
From genes to function: the C. elegans genetic toolboxQ36960940
Two-photon voltage imaging using a genetically encoded voltage indicator.Q37025583
Fluorescent biosensors of protein functionQ37087544
Cortico-cortical projections in mouse visual cortex are functionally target specificQ37256748
Spike inference from calcium imaging using sequential Monte Carlo methods.Q37263350
Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopyQ37324729
In vivo astrocytic Ca(2+) signaling in health and brain disordersQ37414788
Visual receptive field structure of cortical inhibitory neurons revealed by two-photon imaging guided recordingQ37425394
Designs and applications of fluorescent protein-based biosensorsQ37632819
Is astrocyte calcium signaling relevant for synaptic plasticity?Q37814506
Design and application of genetically encoded biosensorsQ37830862
Development of probes for cellular functions using fluorescent proteins and fluorescence resonance energy transferQ37870189
Genetically encoded neural activity indicatorsQ37959220
Chronic calcium imaging in neuronal development and disease.Q37989069
Genetically encoded optical indicators for the analysis of neuronal circuitsQ38038933
Mapping brain circuit function in vivo using two-photon fluorescence microscopy.Q38185981
pHTomato, a red, genetically encoded indicator that enables multiplex interrogation of synaptic activityQ38363583
Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses.Q39751968
Genetically encoded bright Ca2+ probe applicable for dynamic Ca2+ imaging of dendritic spines.Q40374086
Spatially resolved calcium dynamics of mammalian Purkinje cells in cerebellar sliceQ41337206
Multidimensional chemotopic responses to n-aliphatic acid odorants in the rat olfactory bulbQ41673924
Context-dependent computation by recurrent dynamics in prefrontal cortexQ41948067
An optimized fluorescent probe for visualizing glutamate neurotransmissionQ42145581
Calcium dynamics associated with action potentials in single nerve terminals of pyramidal cells in layer 2/3 of the young rat neocortexQ42497273
Choice-specific sequences in parietal cortex during a virtual-navigation decision taskQ42554719
The downs and ups of sensory deprivation: evidence for firing rate homeostasis in vivoQ42819577
Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteinsQ42973103
Simultaneous recording of membrane potential, calcium transient and tension in single muscle fibersQ43799685
Dynamics of spontaneous activity in neocortical slicesQ43818576
Septo-hippocampal GABAergic signaling across multiple modalities in awake mice.Q43965979
Real-time visualization of neuronal activity during perceptionQ44050519
Long-term dendritic spine stability in the adult cortexQ44255207
Two-photon imaging to a depth of 1000 microm in living brains by use of a Ti:Al2O3 regenerative amplifierQ44498542
Spontaneous network activity visualized by ultrasensitive Ca(2+) indicators, yellow Cameleon-NanoQ44756954
In vivo imaging of neuronal activity by targeted expression of a genetically encoded probe in the mouseQ44831759
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous systemQ45007196
Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brainQ45420843
Ca2+ indicators based on computationally redesigned calmodulin-peptide pairsQ46148522
Activation of cerebellar parallel fibers monitored in transgenic mice expressing a fluorescent Ca2+ indicator protein.Q46651519
Vesicle depletion and synaptic depression at a mammalian ribbon synapseQ46923256
Reorganization of cortical population activity imaged throughout long-term sensory deprivationQ48327244
Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice.Q48539274
Reduction of motion artifacts during in vivo two-photon imaging of brain through heartbeat triggered scanning.Q48564753
Reconstruction of firing rate changes across neuronal populations by temporally deconvolved Ca2+ imaging.Q48575015
Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor.Q48798005
Efficient in utero gene transfer system to the developing mouse brain using electroporation: visualization of neuronal migration in the developing cortex.Q48919857
Synchrony between limbic system theta activity and rhythmical behavior in ratsQ48931410
Online correction of licking-induced brain motion during two-photon imaging with a tunable lens.Q48935621
Targeted gene delivery to telencephalic inhibitory neurons by directional in utero electroporation.Q48940105
Two-photon calcium imaging of evoked activity from L5 somatosensory neurons in vivo.Q49066658
Tuning and topography in an odor map on the rat olfactory bulb.Q49071322
Visual cortex neurons: response to stimuli during rapid eye movements.Q49119274
Scanless two-photon excitation of channelrhodopsin-2.Q50540978
Efficient subpixel image registration algorithms.Q51623923
The use of m-sequences in the analysis of visual neurons: linear receptive field propertiesQ74109686
In vivo two-photon microscopy to 1.6-mm depth in mouse cortexQ82215340
Multiple dynamic representations in the motor cortex during sensorimotor learningQ30667690
Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins.Q30769723
Automated correction of fast motion artifacts for two-photon imaging of awake animalsQ30847707
A miniature head-mounted two-photon microscope. high-resolution brain imaging in freely moving animalsQ31013253
Imaging in vivo: watching the brain in actionQ31146515
Imaging cellular network dynamics in three dimensions using fast 3D laser scanningQ33265350
Engineering and characterization of an enhanced fluorescent protein voltage sensorQ33284002
Single fluorescent protein-based Ca2+ sensors with increased dynamic range.Q33289524
Imaging large-scale neural activity with cellular resolution in awake, mobile miceQ33301795
Comparison of generalized phase contrast and computer generated holography for laser image projectionQ33342151
Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movementsQ33346287
High-speed, miniaturized fluorescence microscopy in freely moving mice.Q33373993
Spatiotemporal coherent control using shaped, temporally focused pulsesQ33462785
Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial windowQ33484154
High-speed in vivo calcium imaging reveals neuronal network activity with near-millisecond precisionQ33558418
Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkeyQ33747865
Fiber-optic fluorescence imagingQ33770540
Optical recording of neuronal activity with a genetically-encoded calcium indicator in anesthetized and freely moving miceQ33836915
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensorsQ33842919
Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathwayQ33861167
Circularly permuted green fluorescent proteins engineered to sense Ca2+.Q33937857
Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neuronsQ34017287
Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein.Q34083969
Red-shifted voltage-sensitive fluorescent proteins.Q34092093
A genetically targetable fluorescent probe of channel gating with rapid kineticsQ34105807
Fast two-photon in vivo imaging with three-dimensional random-access scanning in large tissue volumesQ34122441
Synaptic stability and plasticity in a floating world.Q34127724
Electrical spiking in Escherichia coli probed with a fluorescent voltage-indicating proteinQ34201140
In vivo two-photon calcium imaging of neuronal networksQ34201683
Imaging neuronal activity during zebrafish behavior with a genetically encoded calcium indicator.Q34224270
Optical recording of action potentials in mammalian neurons using a microbial rhodopsinQ34236235
Single action potentials and subthreshold electrical events imaged in neurons with a fluorescent protein voltage probe.Q34298285
A FRET-based calcium biosensor with fast signal kinetics and high fluorescence changeQ34354313
Imaging neural spiking in brain tissue using FRET-opsin protein voltage sensors.Q34416550
P304page(s)97
P577publication date2014-12-05
P1433published inFrontiers in Molecular NeuroscienceQ27721913
P1476titleMonitoring activity in neural circuits with genetically encoded indicators
P478volume7

Reverse relations

cites work (P2860)
Q92783476Absorption and Emission Spectroscopic Investigation of the Thermal Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor QuasAr1
Q55353641An improved inverse-type Ca2+ indicator can detect putative neuronal inhibition in Caenorhabditis elegans by increasing signal intensity upon Ca2+ decrease.
Q36128294An integrative role for the superior colliculus in selecting targets for movements
Q36154137Anatomical and functional neuroimaging in awake, behaving marmosets
Q27320798Artificial Induction of Associative Olfactory Memory by Optogenetic and Thermogenetic Activation of Olfactory Sensory Neurons and Octopaminergic Neurons in Drosophila Larvae
Q38645684Automated Functional Analysis of Astrocytes from Chronic Time-Lapse Calcium Imaging Data.
Q57166519Aversive learning-induced plasticity throughout the adult mammalian olfactory system: insights across development
Q89957124Bioelectronics for Millimeter-Sized Model Organisms
Q46955639Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness?
Q28550075Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds
Q92687653Casting a Wide Net to Catch Seizures
Q35927537Contemporary approaches to neural circuit manipulation and mapping: focus on reward and addiction.
Q37703164Context- and Output Layer-Dependent Long-Term Ensemble Plasticity in a Sensory Circuit
Q89756063Differential modulation of excitatory and inhibitory populations of superficial dorsal horn neurons in lumbar spinal cord by Aβ-fiber electrical stimulation
Q38932190Following Optogenetic Dimerizers and Quantitative Prospects
Q53417963Functional Imaging and Optogenetics in Drosophila.
Q50306979Functional Stem Cell Integration into Neural Networks Assessed by Organotypic Slice Cultures.
Q91777465Functional imaging of neuron-astrocyte interactions in a compartmentalized microfluidic device
Q37325475Generation of transgenic marmosets expressing genetically encoded calcium indicators
Q38662564Genetic approaches to retinal research in zebrafish.
Q34541461Genetically Encoded Voltage Indicators: Opportunities and Challenges.
Q38826900Genetically encoded indicators of neuronal activity
Q92287938High frequency, real-time neurochemical and neuropharmacological measurements in situ in the living body
Q47241320Illuminating Brain Activities with Fluorescent Protein-Based Biosensors
Q38840300Image Informatics Strategies for Deciphering Neuronal Network Connectivity
Q63246796Image-Based Profiling of Synaptic Connectivity in Primary Neuronal Cell Culture
Q55004724Imaging Myelination In Vivo Using Transparent Animal Models.
Q36058181Imaging voltage in zebrafish as a route to characterizing a vertebrate functional connectome: promises and pitfalls of genetically encoded indicators.
Q26766226Implications for bidirectional signaling between afferent nerves and urothelial cells-ICI-RS 2014
Q47879536Integration of Plasticity Mechanisms within a Single Sensory Neuron of C. elegans Actuates a Memory
Q92535173Live-Cell Assays for Cell Stress Responses Reveal New Patterns of Cell Signaling Caused by Mutations in Rhodopsin, α-Synuclein and TDP-43
Q39371960Live-cell imaging of cell signaling using genetically encoded fluorescent reporters
Q30358363Marmosets: A Neuroscientific Model of Human Social Behavior.
Q91118029Molecular tools for imaging and recording neuronal activity
Q58089196More than Just a "Motor": Recent Surprises from the Frontal Cortex
Q53822427Optical Electrophysiology in the Developing Heart.
Q38650124Optogenetics enlightens neuroscience drug discovery.
Q64087975Peeking into the sleeping brain: Using in vivo imaging in rodents to understand the relationship between sleep and cognition
Q38557880Probing striatal microcircuitry to understand the functional role of cholinergic interneurons
Q38741707Probing the Complexities of Astrocyte Calcium Signaling
Q36912071Real-time imaging of action potentials in nerves using changes in birefringence
Q92528176Resolving the Micro-Macro Disconnect to Address Core Features of Seizure Networks
Q42331728Scalable electrophysiology in intact small animals with nanoscale suspended electrode arrays.
Q38999025The Growing and Glowing Toolbox of Fluorescent and Photoactive Proteins
Q38931180The Zebrafish Heart as a Model of Mammalian Cardiac Function
Q64268639The kinetic mechanisms of fast-decay red-fluorescent genetically encoded calcium indicators
Q35818543Two-photon directed evolution of green fluorescent proteins
Q42404187Visualizing Presynaptic Calcium Dynamics and Vesicle Fusion with a Single Genetically Encoded Reporter at Individual Synapses
Q39666433What genetic model organisms offer the study of behavior and neural circuits

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