Epidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity

scientific article published on April 2001

Epidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/0264-6021:3550517
P932PMC publication ID1221765
P698PubMed publication ID11284741
P5875ResearchGate publication ID12048551

P2093author name stringX Jiang
J R Couchman
P Tapanadechopone
S Tumova
P2860cites workAntisense targeting of perlecan blocks tumor growth and angiogenesis in vivoQ24564477
Perlecan maintains the integrity of cartilage and some basement membranesQ24680954
Perlecan is essential for cartilage and cephalic developmentQ28146148
Abnormal expression of perlecan proteoglycan in metastatic melanomasQ28240180
A role for perlecan in the suppression of growth and invasion in fibrosarcoma cellsQ28241050
Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfateQ28257965
The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycansQ28259215
The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanasesQ28278296
Regulated diversity of heparan sulfateQ28282444
Matrix proteoglycans: from molecular design to cellular functionQ28284300
Formation of heparan sulfate or chondroitin/dermatan sulfate on recombinant domain I of mouse perlecan expressed in Chinese hamster ovary cellsQ28303061
Perlecan and basement membrane-chondroitin sulfate proteoglycan (bamacan) are two basement membrane chondroitin/dermatan sulfate proteoglycans in the Engelbreth-Holm-Swarm tumor matrixQ28909753
Functions of cell surface heparan sulfate proteoglycansQ29618521
Dermatan sulfate released after injury is a potent promoter of fibroblast growth factor-2 function.Q34475404
The FGF family of growth factors and oncogenesQ35335377
Analysis of affinity and structural selectivity in the binding of proteins to glycosaminoglycans: development of a sensitive electrophoretic approachQ37461866
Localization of glycosaminoglycan substitution sites on domain V of mouse perlecanQ38317495
Proteoglycans and neoplasiaQ39653956
Altered proteoglycan gene expression and the tumor stromaQ40910751
Expression and characterization of human perlecan domains I and II synthesized by baculovirus-infected insect cellsQ40922083
Structural comparison of fibroblast growth factor-specific heparan sulfates derived from a growing or differentiating neuroepithelial cell lineQ41041044
A proteoglycan that activates fibroblast growth factors during early neuronal development is a perlecan variantQ41153435
Recombinant domain III of perlecan promotes cell attachment through its RGDS sequenceQ41381551
C-JUN/AP-1 as possible mediators of tumor necrosis factor-alpha-induced apoptotic response in mouse JB6 tumor cellsQ41385024
A unique heparan sulfate in the nuclei of hepatocytes: structural changes with the growth state of the cells.Q41499345
Differential expression of proteoglycans on the surface of human melanoma cells characterized by altered experimental metastatic potentialQ41611327
Synergistic inhibition of phorbol ester-induced transformation of JB6 cells by transforming growth factor-beta and retinoic acidQ41695436
Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesisQ42476789
Characterization of a dermatan sulfate proteoglycan synthesized by murine parietal yolk sac (PYS-2) cellsQ44018180
12 Analysis of DNA-protein interactions by affinity coelectrophoresisQ44510018
Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levelsQ44528336
Upregulation of fibroblast growth factors and their receptors during multi-stage epidermal carcinogenesis in K14-HPV16 transgenic miceQ46431064
Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate ProteoglycanQ52225676
Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro.Q53437765
Coordinated modulation of the fibroblast growth factor dual receptor mechanism during transformation from human colon adenoma to carcinomaQ59617854
Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesionQ64146688
Structural characterization of the oligosaccharides formed by depolymerization of heparin with nitrous acidQ70044668
Specificity in the interactions of extracellular matrix proteins with subpopulations of the glycosaminoglycan heparinQ70708108
Glycosaminoglycans of pleural mesothelioma: a possible biochemical variant containing chondroitin sulfateQ71551712
Tumor stroma as a regulator of neoplastic behavior. Agonistic and antagonistic elements embedded in the same connective tissueQ71964407
Identification of sites in domain I of perlecan that regulate heparan sulfate synthesisQ73039097
Heparan sulphate proteoglycan expression in human primary liver tumoursQ77407102
Morphological aspects of altered basement membrane metabolism in invasive carcinomas of the breast and the larynxQ77703639
P433issuePt 2
P407language of work or nameEnglishQ1860
P304page(s)517-527
P577publication date2001-04-01
P1433published inBiochemical JournalQ864221
P1476titleEpidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity
P478volume355

Reverse relations

cites work (P2860)
Q34114308Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors
Q37094730Novel interactions of perlecan: unraveling perlecan's role in angiogenesis.
Q35562693Perlecan and tumor angiogenesis
Q33737131Soluble perlecan domain I enhances vascular endothelial growth factor-165 activity and receptor phosphorylation in human bone marrow endothelial cells
Q35070156Syndecan-1 mediates internalization of apoE-VLDL through a low density lipoprotein receptor-related protein (LRP)-independent, non-clathrin-mediated pathway
Q33520086The effect of proteoglycans inhibited by RNA interference on metastatic characters of human salivary adenoid cystic carcinoma