review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Nadia Stefanova | Q64787920 |
Edith Sturm | Q67466675 | ||
P2860 | cites work | Alpha-1-antichymotrypsin gene polymorphism and susceptibility to multiple system atrophy (MSA) | Q81770205 |
Analysis of 14 LRRK2 mutations in Parkinson's plus syndromes and late-onset Parkinson's disease | Q83121503 | ||
Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions | Q83339692 | ||
Definite familial multiple system atrophy with unknown genetics | Q87047617 | ||
Novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology | Q87710261 | ||
Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein | Q88196390 | ||
Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy | Q21142744 | ||
Facioscapulohumeral dystrophy: the path to consensus on pathophysiology | Q21195884 | ||
Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy | Q21198881 | ||
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update | Q22252904 | ||
HDAC6 is a microtubule-associated deacetylase | Q24298013 | ||
The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity | Q24299289 | ||
Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies | Q48401512 | ||
The fragile X premutation presenting as essential tremor | Q48407385 | ||
Immunohistochemical expression of microtubule-associated protein 5 (MAP5) in glial cells in multiple system atrophy | Q48487310 | ||
The SCA17 phenotype can include features of MSA-C, PSP and cognitive impairment | Q48490112 | ||
Traumatic brain injury induces relocalization of DNA-methyltransferase 1. | Q48622304 | ||
Mutant COQ2 in multiple-system atrophy | Q48681803 | ||
Definite multiple system atrophy in a German family | Q48703781 | ||
Probable hereditary multiple system atrophy-autonomic (MSA-A) in a family in the United States | Q48711300 | ||
False-positive SCA8 gene test in a patient with pathologically proven multiple system atrophy | Q49018288 | ||
The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain. | Q49109070 | ||
Features of probable multiple system atrophy patients identified among 4770 patients with parkinsonism enrolled in the multicentre registry of the German Competence Network on Parkinson's disease | Q50276815 | ||
Fragile-X syndrome and fragile X-associated tremor/ataxia syndrome: two faces of FMR1. | Q50277634 | ||
The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases | Q50306250 | ||
Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration. | Q50973856 | ||
An association study of common variation at the MAPT locus with late-onset Alzheimer's disease. | Q51753708 | ||
A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency | Q24540570 | ||
Genome-wide association study reveals genetic risk underlying Parkinson's disease | Q24646654 | ||
p25alpha relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy | Q24682056 | ||
Neurodegenerative diseases: an overview of environmental risk factors | Q24815669 | ||
Nutrition, epigenetics, and metabolic syndrome | Q26829684 | ||
The emerging role of epigenetics in cardiovascular disease | Q26852614 | ||
Role of microRNAs in the reperfused myocardium towards post-infarct remodelling | Q27000076 | ||
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis | Q28115898 | ||
Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein | Q28141645 | ||
Glucocerebrosidase mutations in subjects with parkinsonism | Q28239212 | ||
N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling | Q28265064 | ||
Role of early life exposure and environment on neurodegeneration: implications on brain disorders | Q28386323 | ||
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia | Q29547174 | ||
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease | Q29547175 | ||
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease | Q29614900 | ||
The Agricultural Health Study | Q29615551 | ||
Epigenetic modifications and human disease | Q29619753 | ||
Novel A18T and pA29S substitutions in α-synuclein may be associated with sporadic Parkinson's disease. | Q30352615 | ||
Early life nutrition, epigenetics and programming of later life disease | Q30363211 | ||
The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration | Q30495415 | ||
Multiple system atrophy and amyotrophic lateral sclerosis in a family with hexanucleotide repeat expansions in C9orf72. | Q30580436 | ||
The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA Study Group | Q30991767 | ||
Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE. | Q33181542 | ||
Effect of ApoE and tau on age of onset of progressive supranuclear palsy and multiple system atrophy | Q33182513 | ||
Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia | Q33322579 | ||
Joint genome-wide profiling of miRNA and mRNA expression in Alzheimer's disease cortex reveals altered miRNA regulation | Q33529047 | ||
Consensus statement on the diagnosis of multiple system atrophy. | Q33605440 | ||
Multiple system atrophy--the nature of the beast | Q33631707 | ||
The genetics and epigenetics of autoimmune diseases | Q33642586 | ||
Genetic and epigenetic contributions to human nutrition and health: managing genome-diet interactions | Q33647210 | ||
Glucocerebrosidase mutations in 108 neuropathologically confirmed cases of multiple system atrophy | Q33668478 | ||
Multiple-system atrophy in long-term professional painter: a case report | Q38430500 | ||
Altered expression of miR-202 in cerebellum of multiple-system atrophy | Q38436712 | ||
Mutations in COQ2 in familial and sporadic multiple-system atrophy | Q39140685 | ||
Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy | Q39340274 | ||
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function | Q39545068 | ||
Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease | Q39573183 | ||
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways | Q39975165 | ||
The alpha-synuclein mutation E46K promotes aggregation in cultured cells | Q40344442 | ||
Grading of neuropathology in multiple system atrophy: proposal for a novel scale | Q40398217 | ||
G209A mutant alpha synuclein expression specifically enhances dopamine induced oxidative damage | Q40539190 | ||
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation | Q40964871 | ||
Environmental— occupational risk factors and familial associations in multiple system atrophy: A preliminary investigation | Q41151511 | ||
Arg296 to Cys296 polymorphism in exon 6 of cytochrome P-450-2D6 (CYP2D6) is not associated with multiple system atrophy. | Q41790205 | ||
Spinocerebellar ataxia type 2 with glial cell cytoplasmic inclusions. | Q42004089 | ||
Argyrophilic glial intracytoplasmic inclusions in multiple system atrophy: immunocytochemical and ultrastructural study | Q42030459 | ||
Mutant COQ2 in multiple-system atrophy | Q42403805 | ||
LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions | Q42443503 | ||
Tau is a candidate gene for chromosome 17 frontotemporal dementia | Q42456776 | ||
The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations | Q42469816 | ||
Clinical and pathological features of a Parkinsonian syndrome in a family with an Ala53Thr alpha-synuclein mutation | Q42501526 | ||
Spinocerebellar ataxia type 1 with multiple system degeneration and glial cytoplasmic inclusions | Q42528149 | ||
Reply to: SNCA variants are associated with increased risk of multiple system atrophy | Q43067213 | ||
Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers. | Q43619529 | ||
The Parkinson's disease-associated H50Q mutation accelerates α-Synuclein aggregation in vitro | Q43977429 | ||
Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n | Q44229778 | ||
An association analysis of the rs1572931 polymorphism of the RAB7L1 gene in Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy in China | Q44397924 | ||
Clinical characteristics of the alpha‐synuclein mutation (G209A)‐associated Parkinson's disease in comparison with other forms of familial Parkinson's disease in Greece | Q44444456 | ||
Tau and 14-3-3 in glial cytoplasmic inclusions of multiple system atrophy | Q44481269 | ||
Frequencies of single nucleotide polymorphism in alcohol dehydrogenase7 gene in patients with multiple system atrophy and controls | Q44591956 | ||
Influence of a tumor necrosis factor gene polymorphism in Japanese patients with multiple system atrophy. | Q44598497 | ||
Microglial activation parallels system degeneration in multiple system atrophy | Q44745872 | ||
Alteration of autophagosomal proteins in the brain of multiple system atrophy | Q45266523 | ||
Spinocerebellar ataxia type 17 mutation as a causative and susceptibility gene in parkinsonism | Q46043733 | ||
(123)I-FP-CIT SPET striatal uptake in parkinsonian patients with the alpha-synuclein (G209A) mutation A. | Q46198978 | ||
PRNP M129V homozygosity in multiple system atrophy vs. Parkinson's disease | Q46270768 | ||
Early dopasensitive Parkinsonism related to myotonic dystrophy type 2. | Q46401846 | ||
Parkinsonism and nigrostriatal dysfunction are associated with spinocerebellar ataxia type 6 (SCA6). | Q46544630 | ||
Risk factors of multiple system atrophy: a case-control study in French patients | Q46728310 | ||
Lrrk2 and Lewy body disease | Q46912096 | ||
Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy | Q47772222 | ||
Clinically probable multiple system atrophy with predominant parkinsonism associated with myotonic dystrophy type 2. | Q47803387 | ||
No mutation in the entire coding region of the alpha-synuclein gene in pathologically confirmed cases of multiple system atrophy | Q47935101 | ||
Multiplex families with multiple system atrophy | Q48210479 | ||
Phenotypic variation in a large Swedish pedigree due to SNCA duplication and triplication | Q48298527 | ||
Accumulation of Hsc70 and Hsp70 in glial cytoplasmic inclusions in patients with multiple system atrophy | Q48302627 | ||
G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy | Q48306651 | ||
Tobacco intolerance in multiple system atrophy | Q48326660 | ||
Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron | Q48344985 | ||
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease | Q48353748 | ||
Multiple system atrophy in a patient with the spinocerebellar ataxia 3 gene mutation | Q48354697 | ||
Partial depletion and multiple deletions of muscle mtDNA in familial MNGIE syndrome | Q48370716 | ||
Multiple system atrophy: a primary oligodendrogliopathy. | Q37282526 | ||
Clinical, neuropathological and genotypic variability in SNCA A53T familial Parkinson's disease. Variability in familial Parkinson's disease | Q37309837 | ||
Epigenetics: an important challenge for ICP-MS in metallomics studies | Q37315504 | ||
Biogenesis of mammalian microRNAs: a global view | Q37318597 | ||
Epigenetics and atherosclerosis | Q37398194 | ||
Multiple roles of HDAC inhibition in neurodegenerative conditions. | Q37407855 | ||
Recent developments in multiple system atrophy. | Q37496792 | ||
Association of the MAPT locus with Parkinson's disease | Q37531274 | ||
Lipid dysfunction and pathogenesis of multiple system atrophy | Q37580065 | ||
Mutational analysis of parkin and PINK1 in multiple system atrophy | Q37602290 | ||
Major depression, cognitive dysfunction and Alzheimer's disease: is there a link? | Q37616669 | ||
Multiple system atrophy: an update. | Q37631965 | ||
Epigenetic regulation of oligodendrocyte identity | Q37708828 | ||
Risk factors in the development of multiple sclerosis | Q37754653 | ||
The propagation of prion-like protein inclusions in neurodegenerative diseases | Q37759499 | ||
Epigenetic studies in human diseases | Q37775107 | ||
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts | Q37874476 | ||
Epidemiology and etiology of Parkinson's disease: a review of the evidence | Q37882546 | ||
Interplay between histone deacetylases and autophagy--from cancer therapy to neurodegeneration | Q37962335 | ||
HDAC6 at the Intersection of Neuroprotection and Neurodegeneration. | Q37988922 | ||
Oxidative stress as a cofactor in spinocerebellar ataxia type 2. | Q38008054 | ||
Difference in MSA phenotype distribution between populations: genetics or environment? | Q38128505 | ||
Epigenetics, a key for unlocking complex CNS disorders? Therapeutic implications | Q38214336 | ||
??? | Q64866390 | ||
No association between FMR1 premutations and multiple system atrophy. | Q51934789 | ||
SNCA variants and multiple system atrophy. | Q53471843 | ||
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. | Q53642827 | ||
Frequency analysis and clinical characterization of spinocerebellar ataxia types 1, 2, 3, 6, and 7 in Korean patients. | Q54767792 | ||
Multiple system atrophy | Q56442789 | ||
Variations in the dopamine ?-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy | Q57623839 | ||
Distinctive neuropathology revealed by α-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p | Q57982330 | ||
Case-control study of multiple system atrophy | Q60050838 | ||
A Further Case of Nicotine Sensitivity in Multiple System Atrophy | Q60705186 | ||
Survival in multiple system atrophy | Q63352447 | ||
Smoking habits in multiple system atrophy and progressive supranuclear palsy. European Study Group on Atypical Parkinsonisms | Q64806286 | ||
Absence of G209A and G88C mutations in the alpha-synuclein gene of Parkinson's disease in a Chinese population | Q64821242 | ||
Reduced expression of the G209A alpha-synuclein allele in familial Parkinsonism. | Q64855052 | ||
The G209A mutation in the alpha-synuclein gene is not detected in familial cases of Parkinson disease in non-Greek and/or Italian populations | Q64866695 | ||
Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson's disease | Q64918337 | ||
A Greek-American kindred with autosomal dominant, levodopa-responsive parkinsonism and anticipation | Q72044080 | ||
Multiple system atrophy: sporadic or familial? | Q72230301 | ||
The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons | Q73406764 | ||
Changes in the activity of cdk2 and cdk5 accompany differentiation of rat primary oligodendrocytes | Q73960587 | ||
The G209A mutation in the alpha-synuclein gene in Brazilian families with Parkinson's disease | Q74604430 | ||
Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy | Q74721321 | ||
Survival duration of Parkinson's disease patients living in Greece who carry the G209A alpha-synuclein mutation | Q74721394 | ||
Clinical features of parkinsonian patients with the alpha-synuclein (G209A) mutation | Q77365028 | ||
Interleukin-1A (-889) genetic polymorphism increases the risk of multiple system atrophy | Q79324940 | ||
The ADH1C stop mutation in multiple system atrophy patients and healthy probands in the United Kingdom and Germany | Q80231312 | ||
Epidemiology of multiple system atrophy: a prevalence and pilot risk factor study in Aquitaine, France | Q80375902 | ||
Interleukin-8, intercellular adhesion molecule-1 and tumour necrosis factor-alpha gene polymorphisms and the risk for multiple system atrophy | Q81163858 | ||
Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes | Q81167672 | ||
Heredity in multiple system atrophy | Q81530223 | ||
Glial cell cytoplasmic inclusions in SCA2 do not express alpha-synuclein | Q81657484 | ||
Identification of circulating microRNAs for the differential diagnosis of Parkinson's disease and Multiple System Atrophy. | Q33732095 | ||
A novel cytochrome P-450IID6 (CYPIID6) mutant gene associated with multiple system atrophy | Q33733799 | ||
Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. | Q33738316 | ||
Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. | Q33920767 | ||
The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells. | Q33991720 | ||
Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells | Q34246998 | ||
Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease. | Q34330786 | ||
SHC2 gene copy number in multiple system atrophy (MSA) | Q34381056 | ||
Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990. | Q34446721 | ||
Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome). | Q34458365 | ||
Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease | Q34612168 | ||
Inflammation in neurodegenerative disease--a double-edged sword | Q34775762 | ||
Multiple system atrophy following chronic carbon disulfide exposure | Q34938797 | ||
Cognitive neuroepigenetics: a role for epigenetic mechanisms in learning and memory | Q35036785 | ||
Cyclin-dependent kinase 5 is a regulator of podocyte differentiation, proliferation, and morphology | Q35103283 | ||
Clinical phenotype in patients with alpha-synuclein Parkinson's disease living in Greece in comparison with patients with sporadic Parkinson's disease | Q35462051 | ||
Probable multiple system atrophy in a German family | Q35481282 | ||
Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis | Q35751839 | ||
Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group | Q35753957 | ||
Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration | Q36040875 | ||
The alpha-synuclein gene in multiple system atrophy | Q36142276 | ||
SNCA variants are associated with increased risk for multiple system atrophy | Q36460907 | ||
Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy | Q36500789 | ||
Pathology and genetics of multiple system atrophy: an approach to determining genetic susceptibility spectrum | Q36541685 | ||
Heterozygosity for a Mendelian disorder as a risk factor for complex disease | Q36590714 | ||
CYP2D6-debrisoquine hydroxylase gene polymorphism in multiple system atrophy. | Q36691548 | ||
Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD. | Q36793926 | ||
A novel α-synuclein missense mutation in Parkinson disease | Q36841475 | ||
Apolipoprotein E e4 allele frequency in patients with multiple system atrophy | Q36856567 | ||
Multiple-system atrophy is genetically distinct from identified inherited causes of spinocerebellar degeneration | Q36894828 | ||
Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors | Q36920474 | ||
α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? | Q36925651 | ||
Epigenetic codes in cognition and behaviour. | Q37114225 | ||
MicroRNA function is required for neurite outgrowth of mature neurons in the mouse postnatal cerebral cortex | Q37168678 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P921 | main subject | multiple system atrophy | Q1541975 |
P304 | page(s) | 277-291 | |
P577 | publication date | 2014-12-12 | |
P1433 | published in | Experimental neurobiology | Q26842060 |
P1476 | title | Multiple system atrophy: genetic or epigenetic? | |
P478 | volume | 23 |
Q37219569 | Aging of perennial cells and organ parts according to the programmed aging paradigm. |
Q35952063 | Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications |
Q35955278 | Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation |
Q90164342 | Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients |
Q49562668 | Multiple System Atrophy: An Oligodendroglioneural Synucleinopathy |
Q46726761 | Multiple system atrophy: experimental models and reality |
Q38813304 | Multiple system atrophy: pathogenic mechanisms and biomarkers |
Q38809733 | Neuroprotection by Epigenetic Modulation in a Transgenic Model of Multiple System Atrophy |
Q26770919 | Review: Multiple system atrophy: emerging targets for interventional therapies |
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