Glycoprotein VI oligomerization in cell lines and platelets

scientific article published on 15 March 2007

Glycoprotein VI oligomerization in cell lines and platelets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1538-7836.2007.02449.X
P932PMC publication ID1869045
P698PubMed publication ID17367493
P5875ResearchGate publication ID6440897

P50authorSteve P. WatsonQ37383398
Michael G TomlinsonQ56999433
P2093author name stringJon Frampton
Simon J Davis
Teresa Bori-Sanz
John R James
Oscar Berlanga
P2860cites workA patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesionQ24621493
The small GTPase Rap1b regulates the cross talk between platelet integrin alpha2beta1 and integrin alphaIIbbeta3Q24685934
Structure of the snake-venom toxin convulxinQ27642814
Human blood platelets showing no response to collagen fail to express surface glycoprotein IaQ28114845
Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chainQ28145083
Platelet-collagen interaction: is GPVI the central receptor?Q28185377
Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagenQ28204718
CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylatedQ30745665
Collagen-platelet interactions: recognition and signallingQ35572217
Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifsQ35863914
Platelet glycoprotein VI: its structure and functionQ35894228
Functional consequences of 7TM receptor dimerizationQ35965096
Convergence on a distinctive assembly mechanism by unrelated families of activating immune receptors.Q36304347
Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in miceQ36376147
Stimulatory function of paired immunoglobulin-like receptor-A in mast cell line by associating with subunits common to Fc receptorsQ38319674
The Fc receptor gamma-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxinQ40724056
Functional association of FcepsilonRIgamma with arginine(632) of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophagesQ40930532
Phosphatidylinositol 3-kinase mediates the inhibitory effect of epidermal growth factor on calcium-dependent chloride secretionQ41157432
Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2.Q42917596
Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoformsQ44074346
Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins.Q44355152
GPVI-deficient mice lack collagen responses and are protected against experimentally induced pulmonary thromboembolismQ46684669
Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo.Q51831538
Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI.Q51936883
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletionQ52550457
Integrin α2-Deficient Mice Develop Normally, Are Fertile, but Display Partially Defective Platelet Interaction with CollagenQ57339936
A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transferQ61951097
The role of ITAM- and ITIM-coupled receptors in platelet activation by collagenQ63408039
Platelets with 10% of the normal amount of glycoprotein VI have an impaired response to collagen that results in a mild bleeding tendencyQ71670281
Functional role of the antigen recognized by an antiplatelet antibody specific for a putative collagen receptor in platelet-collagen interactionQ72101142
Electrostatic fasteners hold the T cell receptor-CD3 complex togetherQ78817864
Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in miceQ80913351
The alpha2beta1 integrin is a necessary co-receptor for collagen-induced activation of Syk and the subsequent phosphorylation of phospholipase Cgamma2 in plateletsQ95826520
P433issue5
P304page(s)1026-1033
P577publication date2007-03-15
P1433published inJournal of Thrombosis and HaemostasisQ6296004
P1476titleGlycoprotein VI oligomerization in cell lines and platelets
P478volume5

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cites work (P2860)
Q38862626A nanostructured synthetic collagen mimic for hemostasis
Q38867733Beyond antiplatelets: The role of glycoprotein VI in ischemic stroke
Q37696519Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets.
Q40086475Collagen promotes sustained glycoprotein VI signaling in platelets and cell lines.
Q92228934Comparison of the GPVI inhibitors losartan and honokiol
Q36215984Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood
Q59281484Ligand Binding Rapidly Induces Disulfide-dependent Dimerization of Glycoprotein VI on the Platelet Plasma Membrane
Q38874473Model systems for platelet receptor shedding
Q37762389New therapeutic strategies targeting transmembrane signal transduction in the immune system
Q37071700Platelet receptor redox regulation
Q38117745Platelet receptors activated via mulitmerization: glycoprotein VI, GPIb-IX-V, and CLEC-2.
Q37696321Protein intrinsic disorder and oligomericity in cell signaling
Q37344397SCHOOL model and new targeting strategies
Q37463580Structural insights into the interactions between platelet receptors and fibrillar collagen.
Q49834468Targeting Intramembrane Protein-Protein Interactions: Novel Therapeutic Strategy of Millions Years Old.
Q33351190The SCHOOL of nature: I. Transmembrane signaling
Q41768887The SCHOOL of nature: II. Protein order, disorder and oligomericity in transmembrane signaling
Q34619705The SCHOOL of nature: III. From mechanistic understanding to novel therapies
Q38377767TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS.

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