scholarly article | Q13442814 |
P2093 | author name string | Liu X | |
Berk AJ | |||
Yew PR | |||
P433 | issue | 2 | |
P921 | main subject | Adenoviridae | Q193447 |
P304 | page(s) | 190-202 | |
P577 | publication date | 1994-01-01 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53. | |
P478 | volume | 8 |
Q34764233 | 2-aminopurine enhances the oncolytic activity of an E1b-deleted adenovirus in hepatocellular carcinoma cells |
Q40546338 | A conditionally replicating adenovirus for nasopharyngeal carcinoma gene therapy. |
Q33827516 | A functional complex of adenovirus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity. |
Q36808087 | A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4. |
Q38353922 | A hydrophobic region within the adenovirus E1B 19 kDa protein is necessary for the transient inhibition of NF-kappaB activated by different stimuli. |
Q39852886 | A novel domain in adenovirus L4-100K is required for stable binding and efficient inhibition of human granzyme B: possible interaction with a species-specific exosite |
Q45876577 | A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function |
Q93199947 | ATO (Arsenic Trioxide) Effects on Promyelocytic Leukemia Nuclear Bodies Reveals Antiviral Intervention Capacity |
Q40169121 | Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes |
Q34895124 | Adenoviral inhibitors of apoptotic cell death |
Q40628992 | Adenovirus 2 E1B-55K protein relieves p53-mediated transcriptional repression of the survivin and MAP4 promoters |
Q39575238 | Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription |
Q64382715 | Adenovirus E1B 19-kDa death suppressor protein interacts with Bax but not with Bad |
Q24297809 | Adenovirus E1B 55-kilodalton oncoprotein binds to Daxx and eliminates enhancement of p53-dependent transcription by Daxx |
Q33964757 | Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. |
Q34301861 | Adenovirus E1B 55-kilodalton protein is required for both regulation of mRNA export and efficient entry into the late phase of infection in normal human fibroblasts |
Q37391112 | Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation |
Q24523301 | Adenovirus E1B 55K represses p53 activation in vitro. |
Q39421013 | Adenovirus E4orf3 targets transcriptional intermediary factor 1γ for proteasome-dependent degradation during infection |
Q37983134 | Adenovirus degradation of cellular proteins. |
Q39612520 | Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex |
Q34573981 | Adenovirus infection of primary malignant lymphoid cells |
Q35488742 | Adenovirus replaces mitotic checkpoint controls |
Q38893456 | Adenovirus type 12 E1B 55-kilodalton oncoprotein promotes p53-mediated apoptotic response of ovarian cancer to cisplatin |
Q35891411 | Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture |
Q39578554 | Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function. |
Q41786916 | Adenovirus type 5 early region 1B 156R protein promotes cell transformation independently of repression of p53-stimulated transcription |
Q28574947 | Adenovirus type 5 early region 1B 55K oncoprotein-dependent degradation of cellular factor Daxx is required for efficient transformation of primary rodent cells |
Q35868343 | Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis |
Q35850341 | Adenovirus type 5 exerts genome-wide control over cellular programs governing proliferation, quiescence, and survival |
Q36759991 | Aggresome formation by the adenoviral protein E1B55K is not conserved among adenovirus species and is not required for efficient degradation of nuclear substrates |
Q39906835 | An avian cell line designed for production of highly attenuated viruses |
Q39960855 | An early function of the adenoviral E1B 55 kDa protein is required for the nuclear relocalization of the cellular p53 protein in adenovirus-infected normal human cells |
Q39602482 | Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein |
Q33641023 | Analysis of synthesis, stability, phosphorylation, and interacting polypeptides of the 34-kilodalton product of open reading frame 6 of the early region 4 protein of human adenovirus type 5 |
Q24538586 | Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery |
Q39549322 | Baculovirus p33 binds human p53 and enhances p53-mediated apoptosis. |
Q37574153 | Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. |
Q39835775 | Cell lines from the Egyptian fruit bat are permissive for modified vaccinia Ankara |
Q35847043 | Cell type-specific inhibition of p53-mediated apoptosis by mdm2. |
Q30860353 | Cell-specific modulation of papovavirus replication by tumor suppressor protein p53 |
Q34225918 | Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned? |
Q45861487 | Conditionally replicating viruses in cancer therapy |
Q40902810 | Consequences of disruption of the interaction between p53 and the larger adenovirus early region 1B protein in adenovirus E1 transformed human cells |
Q36484050 | Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity |
Q37632435 | Converting cancer genes into killer genes |
Q39445508 | Corepressor required for adenovirus E1B 55,000-molecular-weight protein repression of basal transcription |
Q53270092 | Cross-talk between phosphorylation and SUMOylation regulates transforming activities of an adenoviral oncoprotein. |
Q40972382 | Definition of a major p53 binding site on Ad2E1B58K protein and a possible nuclear localization signal on the Ad12E1B54K protein |
Q29041391 | Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex |
Q35941628 | Deregulation of the cell cycle by the Epstein-Barr virus |
Q64382573 | Detection of group C adenovirus DNA in small-cell lung cancer with the nested polymerase chain reaction |
Q35835238 | Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation |
Q36551539 | Direct transcriptional repression by pRB and its reversal by specific cyclins |
Q39446048 | Distinct regulation of p53 and p73 activity by adenovirus E1A, E1B, and E4orf6 proteins |
Q39963290 | Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates |
Q104607567 | Double-edged Role of PML Nuclear Bodies during Human Adenovirus Infection |
Q38317803 | E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. |
Q24312647 | E1B 55-kilodalton-associated protein: a cellular protein with RNA-binding activity implicated in nucleocytoplasmic transport of adenovirus and cellular mRNAs |
Q40481068 | Effects of febrile temperature on adenoviral infection and replication: implications for viral therapy of cancer. |
Q35853884 | Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit |
Q35852705 | Efficient nuclear localization and immortalizing ability, two functions dependent on the adenovirus type 5 (Ad5) E1A second exon, are necessary for cotransformation with Ad5 E1B but not with T24ras |
Q39685569 | Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes. |
Q34529776 | Export of adenoviral late mRNA from the nucleus requires the Nxf1/Tap export receptor |
Q41447210 | Fluctuating expression of microRNAs in adenovirus infected cells |
Q45744096 | Functional impairment of p73 and p51, the p53-related proteins, by the human T-cell leukemia virus type 1 Tax oncoprotein |
Q24290998 | Functional inactivation of p73, a homolog of p53 tumor suppressor protein, by human papillomavirus E6 proteins |
Q33781719 | Genomic and bioinformatics analysis of HAdV-4, a human adenovirus causing acute respiratory disease: implications for gene therapy and vaccine vector development |
Q45880712 | Genomic and bioinformatics analysis of HAdV-7, a human adenovirus of species B1 that causes acute respiratory disease: implications for vector development in human gene therapy |
Q24554388 | HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor |
Q38326994 | High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens. |
Q64377201 | How adenovirus strives to control cellular gene expression |
Q24336890 | Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain |
Q35873729 | Human cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription |
Q33835387 | Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex |
Q41034641 | Identification of transcriptional activation and repression domains in human CCAAT/enhancer-binding protein epsilon |
Q35111076 | Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53. |
Q33810466 | Induction of p53-independent apoptosis by the adenovirus E4orf4 protein requires binding to the Balpha subunit of protein phosphatase 2A. |
Q33825089 | Induction of transformation and p53-dependent apoptosis by adenovirus type 5 E4orf6/7 cDNA. |
Q35140413 | Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents |
Q43831424 | Inhibition of the putative tumor suppressor gene TIMP-3 by tumor-derived p53 mutants and wild type p53. |
Q33292209 | Interaction between the HPV-16 E2 transcriptional activator and p53. |
Q36434260 | KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification |
Q37727809 | Krüppel-associated box-mediated repression of RNA polymerase II promoters is influenced by the arrangement of basal promoter elements |
Q48067606 | Mammary tumors induced by human adenovirus type 9: a role for the viral early region 4 gene |
Q28140555 | Marek's disease herpesvirus transforming protein MEQ: a c-Jun analogue with an alternative life style |
Q35572466 | Mdm2: A regulator of cell growth and death |
Q53656970 | Modulation of host cell gene expression during onset of the late phase of an adenovirus infection is focused on growth inhibition and cell architecture. |
Q41290133 | Molecular and clinical aspects of apoptosis |
Q28577102 | Molecular cloning of a novel transcriptional repressor protein of the rat type 1 vasoactive intestinal peptide receptor gene |
Q28141883 | NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells. Implication of NBS1 in alternative lengthening of telomeres |
Q24530146 | Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain |
Q33957704 | New insights into the mechanism of inhibition of p53 by simian virus 40 large T antigen |
Q40353337 | Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein |
Q33887076 | Nuclear export of the E1B 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a rev-like signal sequence |
Q34115253 | ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus |
Q37247046 | Oncogenic potential of the adenovirus E4orf6 protein |
Q34571752 | Oncolytic biotherapy: a novel therapeutic plafform |
Q34452020 | Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): results of phase I and II trials |
Q34074708 | Oncolytic viruses as novel anticancer agents: turning one scourge against another |
Q35902523 | Oncolytic viruses for the treatment of cancer: current strategies and clinical trials. |
Q38020107 | Oncolytic viruses in the treatment of cancer: a review of current strategies |
Q41792379 | PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53. |
Q36759358 | Poly(β-amino ester) nanoparticle delivery of TP53 has activity against small cell lung cancer in vitro and in vivo |
Q74643391 | Protein kinase CK2 interacts with a multi-protein binding domain of p53 |
Q34519693 | RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence |
Q33861763 | RBP1 induces growth arrest by repression of E2F-dependent transcription |
Q24554426 | RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins |
Q34469114 | Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus |
Q24678703 | Regulation of apoptosis by viral gene products |
Q35883364 | Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells. |
Q35882839 | Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5. |
Q24337326 | Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7 |
Q24655012 | Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene |
Q35755347 | Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein |
Q39582723 | Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells. |
Q39792211 | Replication of damaged DNA in vitro is blocked by p53. |
Q34293607 | Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer |
Q24336020 | Repression of p53-mediated transcription by MDM2: a dual mechanism |
Q40185681 | Repression of p53-mediated transcription by adenovirus E1B 55-kDa does not require corepressor mSin3A and histone deacetylases |
Q40410984 | Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins. |
Q36556040 | Reversal of in vitro p53 squelching by both TFIIB and TFIID |
Q28513708 | Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression |
Q39174506 | Role of E1B55K in E4orf6/E1B55K E3 ligase complexes formed by different human adenovirus serotypes |
Q36039006 | Role of the RNA recognition motif of the E1B 55 kDa protein in the adenovirus type 5 infectious cycle |
Q33649728 | Roles for the E4 orf6, orf3, and E1B 55-kilodalton proteins in cell cycle-independent adenovirus replication |
Q24338995 | SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML |
Q33944482 | SUMO-1 modification required for transformation by adenovirus type 5 early region 1B 55-kDa oncoprotein |
Q46061653 | Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents |
Q24290549 | Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1 |
Q34227735 | Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis |
Q39619768 | Serotype-specific inactivation of the cellular DNA damage response during adenovirus infection |
Q40947307 | Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation |
Q38349921 | Strategic Attack on Host Cell Gene Expression during Adenovirus Infection |
Q39878070 | Structural analysis of the adenovirus type 5 E1B 55-kilodalton-E4orf6 protein complex |
Q53891195 | Structure of the adenovirus E4 Orf6 protein predicted by fold recognition and comparative protein modeling. |
Q38811135 | The Dual Nature of Nek9 in Adenovirus Replication |
Q40700516 | The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F. |
Q42055738 | The N terminus of p53 regulates its dissociation from DNA. |
Q42557316 | The WTX tumor suppressor enhances p53 acetylation by CBP/p300 |
Q37145192 | The adenoviral E1B 55-kilodalton protein controls expression of immune response genes but not p53-dependent transcription |
Q35991794 | The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function |
Q40976806 | The adenovirus E4orf6 protein contributes to malignant transformation by antagonizing E1A-induced accumulation of the tumor suppressor protein p53. |
Q30888959 | The adenovirus-2 E1B-55K protein interacts with a mSin3A/histone deacetylase 1 complex |
Q64379637 | The cytotoxic effect of E1B 55-kDa mutant adenovirus on human hepatocellular carcinoma cell lines |
Q38354882 | The dual effect of adenovirus type 5 E1A 13S protein on NF-kappaB activation is antagonized by E1B 19K. |
Q35875344 | The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle |
Q33783779 | The early region 4 orf4 protein of human adenovirus type 5 induces p53-independent cell death by apoptosis |
Q34388476 | The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells |
Q64082124 | The human adenovirus type 5 E1B 55kDa protein interacts with RNA promoting timely DNA replication and viral late mRNA metabolism |
Q36556883 | The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-kappa B, c-Fos, and c-Jun activities |
Q28282671 | The papillomavirus E6 proteins |
Q33599759 | The regulation of apoptosis by microbial pathogens. |
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Q33838380 | Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy |
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Q28302177 | Transcriptional activity of the paired-like homeodomain proteins CHX10 and VSX1 |
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