Systematic review and meta-analysis of randomized clinical trials comparing efficacy and safety outcomes of insulin glargine with NPH insulin, premixed insulin preparations or with insulin detemir in type 2 diabetes mellitus

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Systematic review and meta-analysis of randomized clinical trials comparing efficacy and safety outcomes of insulin glargine with NPH insulin, premixed insulin preparations or with insulin detemir in type 2 diabetes mellitus is …
instance of (P31):
review articleQ7318358
meta-analysisQ815382
scholarly articleQ13442814

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P6179Dimensions Publication ID1017730776
P356DOI10.1007/S00592-014-0698-4
P932PMC publication ID4506471
P698PubMed publication ID25585592
P5875ResearchGate publication ID270909691

P50authorMaciej T. MałeckiQ89424369
Piotr WojciechowskiQ60312713
P2093author name stringPrzemyslaw Rys
Joanna Lis
Agnieszka Rogoz-Sitek
Albert Syta
Grzegorz Niesyczyński
P2860cites workPreferred reporting items for systematic reviews and meta-analyses: the PRISMA statementQ21562278
Insulin detemir versus insulin glargine for type 2 diabetes mellitusQ24235596
Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitusQ24245192
Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of DiabetesQ24642503
Insulin therapy and risk of prostate cancer: a systematic review and meta-analysis of observational studiesQ26823071
Insulin use and cancer risk in patients with type 2 diabetes: a systematic review and meta-analysis of observational studiesQ27025720
Assessing the quality of reports of randomized clinical trials: is blinding necessary?Q27860973
Standards of medical care in diabetes--2014Q28304435
Adding insulin glargine vs. NPH insulin to metformin results in a more efficient postprandial beta-cell protection in individuals with type 2 diabetesQ33853992
Initiating insulin therapy in type 2 Diabetes: a comparison of biphasic and basal insulin analogsQ33984638
ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collabQ34368081
Prandial–basal insulin regimens plus oral antihyperglycaemic agents to improve mealtime glycaemia: initiate and progressively advance insulin therapy in type 2 diabetesQ34381425
Insulin glargine in the management of diabetes mellitus: an evidence-based assessment of its clinical efficacy and economic value.Q34449820
Effects of insulin glargine versus metformin on glycemic variability, microvascular and beta-cell function in early type 2 diabetesQ34594675
Insulin glargine: a new basal insulinQ34648626
Insulin glargine compared to NPH among insulin-naïve, U.S. inner city, ethnic minority type 2 diabetic patientsQ34663438
Clinical pharmacokinetics and pharmacodynamics of insulin lispro mixturesQ34982117
American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care planQ83808238
Fluctuation of serum basal insulin levels following single and multiple dosing of insulin glargineQ83874724
Comparison of insulin lispro protamine suspension versus insulin glargine once daily in basal-bolus therapies with insulin lispro in type 2 diabetes patients: a prospective randomized open-label trialQ84701617
Addition of insulin lispro protamine suspension or insulin glargine to oral type 2 diabetes regimens: a randomized trialQ85154736
Diabetes, insulin use, smoking, and pancreatic cancer mortality in TaiwanQ86424484
Indirect comparison of once daily insulin detemir and glargine in reducing weight gain and hypoglycaemic episodes when administered in addition to conventional oral anti-diabetic therapy in patients with type-2 diabetesQ47222394
A study comparing insulin lispro mix 25 with glargine plus lispro therapy in patients with Type 2 diabetes who have inadequate glycaemic control on oral anti-hyperglycaemic medication: results of the PARADIGM study.Q48432586
Postprandial serum C-peptide to plasma glucose ratio predicts future insulin therapy in Japanese patients with type 2 diabetes.Q51534382
Therapy in type 2 diabetes: insulin glargine vs. NPH insulin both in combination with glimepiride.Q51941134
A One-year, Randomised, Multicentre Trial Comparing Insulin Glargine with NPH Insulin in Combination with Oral Agents in Patients with Type 2 DiabetesQ53862758
Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.Q55034466
U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study GroupQ56914456
Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)Q57412648
Starting insulin therapy in type 2 diabetes: twice-daily biphasic insulin Aspart 30 plus metformin versus once-daily insulin glargine plus glimepirideQ79370979
Long-acting insulin analogues versus NPH human insulin in type 2 diabetes: a meta-analysisQ81317578
Intensive glucose control and macrovascular outcomes in type 2 diabetes.Q34995674
Use of insulin and insulin analogs and risk of cancer - systematic review and meta-analysis of observational studies.Q35038355
Practical approaches to insulin therapy for type 2 diabetes mellitus with premixed insulin analoguesQ36274535
Efficacy of biphasic insulin aspart in patients with type 2 diabetesQ36414686
Basal supplementation of insulin lispro protamine suspension versus insulin glargine and detemir for type 2 diabetes: meta-analysis of randomized controlled trialsQ36426817
A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetesQ36449523
Systematic review: comparative effectiveness and safety of premixed insulin analogues in type 2 diabetesQ36602652
A review of human and analogue insulin trialsQ36656636
Association of clinical symptomatic hypoglycemia with cardiovascular events and total mortality in type 2 diabetes: a nationwide population-based studyQ36720223
Prandial premixed insulin analogue regimens versus basal insulin analogue regimens in the management of type 2 diabetes: an evidence-based comparisonQ37013205
DURAbility of basal versus lispro mix 75/25 insulin efficacy (DURABLE) trial 24-week results: safety and efficacy of insulin lispro mix 75/25 versus insulin glargine added to oral antihyperglycemic drugs in patients with type 2 diabetesQ37189266
Similar progression of diabetic retinopathy with insulin glargine and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes: a long-term, randomised, open-label studyQ37296843
Epidemiological aspects of neoplasms in diabetesQ37727058
Relationship of insulin dose, A1c lowering, and weight in type 2 diabetes: comparing insulin glargine and insulin detemirQ37815511
Long-acting insulin analogs: a review of "real-world" effectiveness in patients with type 2 diabetesQ37818351
Metabolic control and risk of hypoglycaemia during the first year of intensive insulin treatment in type 2 diabetes: systematic review and meta-analysisQ37964744
Systematic review and meta-analysis of insulin therapy and risk of cancer.Q38005000
Randomized, open-label, parallel-group evaluations of basal-bolus therapy versus insulin lispro premixed therapy in patients with type 2 diabetes mellitus failing to achieve control with starter insulin treatment and continuing oral antihyperglycemiQ38371451
Safety and efficacy of glargine compared with NPH insulin for the treatment of Type 2 diabetes: a meta-analysis of randomized controlled trialsQ38898058
A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugs.Q40717578
Basal insulin and cardiovascular and other outcomes in dysglycemiaQ42507791
Effect of normalization of fasting glucose by intensified insulin therapy and influence of eNOS polymorphisms on the incidence of restenosis after peripheral angioplasty in patients with type 2 diabetes: a randomized, open-label clinical trial.Q42511510
A 52-week, multinational, open-label, parallel-group, noninferiority, treat-to-target trial comparing insulin detemir with insulin glargine in a basal-bolus regimen with mealtime insulin aspart in patients with type 2 diabetesQ42607495
Pronounced weight gain in insulin-treated patients with type 2 diabetes mellitus is associated with an unfavourable cardiometabolic risk profileQ42790410
Severe hypoglycemia and risks of vascular events and deathQ42868535
Impact of race/ethnicity on the efficacy and safety of commonly used insulin regimens: a post hoc analysis of clinical trials in type 2 diabetes mellitusQ43075550
Starting insulin therapy with basal insulin analog or premix insulin analog in T2DM: a pooled analysis of treat-to-target trialsQ43080195
Comparison between a basal-bolus and a premixed insulin regimen in individuals with type 2 diabetes-results of the GINGER studyQ43187037
Once-daily initiation with biphasic insulin aspart 30 versus insulin glargine in patients with type 2 diabetes inadequately controlled with oral drugs: an open-label, multinational RCT.Q43263307
Basal insulin therapy in type 2 diabetes: 28-week comparison of insulin glargine (HOE 901) and NPH insulinQ43584177
Glimepiride combined with morning insulin glargine, bedtime neutral protamine hagedorn insulin, or bedtime insulin glargine in patients with type 2 diabetes. A randomized, controlled trialQ44479625
The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patientsQ44631767
Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetesQ45242316
Comparison of insulin detemir and insulin glargine using a basal-bolus regimen in a randomized, controlled clinical study in patients with type 2 diabetes.Q45946807
Hypoglycaemia is more frequent in type 2 diabetic patients with co-morbid vascular disease: an analysis of the DiaRegis registryQ46220548
Addition of neutral protamine lispro insulin or insulin glargine to oral type 2 diabetes regimens for patients with suboptimal glycemic control: a randomized trialQ46308233
Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetesQ46406475
Mealtime 50/50 basal + prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and pre- and postprandial blood glucose levels in patients with type 2 diabetes: a multinational, 24-weekQ46834143
Efficacy and treatment satisfaction of once-daily insulin glargine plus one or two oral antidiabetic agents versus continuing premixed human insulin in patients with type 2 diabetes previously on long-term conventional insulin therapy: the Switch piQ46866724
Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET studyQ46926372
Advancing insulin therapy in type 2 diabetes previously treated with glargine plus oral agents: prandial premixed (insulin lispro protamine suspension/lispro) versus basal/bolus (glargine/lispro) therapyQ46953005
Negative binomial meta-regression analysis of combined glycosylated hemoglobin and hypoglycemia outcomes across eleven Phase III and IV studies of insulin glargine compared with neutral protamine Hagedorn insulin in type 1 and type 2 diabetes mellitQ46963862
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P921main subjecthormoneQ11364
preproinsulinQ7240673
insulin detemirQ410965
insulin glargineQ417317
meta-analysisQ815382
peptideQ172847
systematic reviewQ1504425
NPH insulinQ1929845
type 2 diabetesQ3025883
biomedical investigative techniqueQ66648976
P304page(s)649-662
P577publication date2015-01-14
2015-08-01
P1433published inActa DiabetologicaQ15749690
P1476titleSystematic review and meta-analysis of randomized clinical trials comparing efficacy and safety outcomes of insulin glargine with NPH insulin, premixed insulin preparations or with insulin detemir in type 2 diabetes mellitus
P478volume52

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cites work (P2860)
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Q64239470Basal insulin therapy: Unmet medical needs in Asia and the new insulin glargine in diabetes treatment
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Q40963671Glargine insulin/gliclazide MR combination therapy is more effective than premixed insulin monotherapy in Chinese patients with type 2 diabetes inadequately controlled on oral antidiabetic drugs
Q92684714HbA1c target achievement in the elderly: results of the Titration and Optimization trial for initiation of insulin glargine 100 U/mL in patients with type 2 diabetes poorly controlled on oral antidiabetic drugs
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