scholarly article | Q13442814 |
P50 | author | Daniel P Raleigh | Q56423022 |
Vadim Patsalo | Q59601192 | ||
D F Green | Q73676610 | ||
P2093 | author name string | David F Green | |
P2860 | cites work | Printed covalent glycan array for ligand profiling of diverse glycan binding proteins | Q24559665 |
How frequent are correlated changes in families of protein sequences? | Q24562368 | ||
Sequence logos: a new way to display consensus sequences | Q24598387 | ||
The Pfam protein families database | Q24644670 | ||
CHARMM: the biomolecular simulation program | Q24658108 | ||
Potent anti-influenza activity of cyanovirin-N and interactions with viral hemagglutinin | Q24680353 | ||
Crystal structure of cyanovirin-N, a potent HIV-inactivating protein, shows unexpected domain swapping | Q27618183 | ||
Solution structure of a cyanovirin-N:Man alpha 1-2Man alpha complex: structural basis for high-affinity carbohydrate-mediated binding to gp120 | Q27635270 | ||
The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures | Q27639001 | ||
A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity | Q27646788 | ||
The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity | Q27650286 | ||
Solution and Crystal Structures of a Sugar Binding Site Mutant of Cyanovirin-N: No Evidence of Domain Swapping | Q27651425 | ||
Anti-HIV Activity of Defective Cyanovirin-N Mutants Is Restored by Dimerization | Q27659715 | ||
Solution Structure of the Monovalent Lectin Microvirin in Complex with Man (1-2)Man Provides a Basis for Anti-HIV Activity with Low Toxicity | Q27667444 | ||
Structure-Function Analysis of a CVNH-LysM Lectin Expressed during Plant Infection by the Rice Blast Fungus Magnaporthe oryzae | Q27667816 | ||
Designed oligomers of cyanovirin-N show enhanced HIV neutralization | Q27671182 | ||
Are buried salt bridges important for protein stability and conformational specificity? | Q27730229 | ||
Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme | Q27731429 | ||
Amino-acid substitutions in a surface turn modulate protein stability | Q27732236 | ||
Design, structure and stability of a hyperthermophilic protein variant | Q27758864 | ||
Solution structure of cyanovirin-N, a potent HIV-inactivating protein | Q27764577 | ||
High-resolution protein design with backbone freedom | Q27766051 | ||
Effect of the extra n-terminal methionine residue on the stability and folding of recombinant alpha-lactalbumin expressed in Escherichia coli | Q27766482 | ||
All-atom empirical potential for molecular modeling and dynamics studies of proteins | Q27860468 | ||
WebLogo: A Sequence Logo Generator | Q27860646 | ||
NMRPipe: a multidimensional spectral processing system based on UNIX pipes | Q27860859 | ||
Computer-based redesign of a protein folding pathway | Q28203951 | ||
Solvation energy in protein folding and binding | Q28307568 | ||
Antibody neutralization and escape by HIV-1 | Q29547345 | ||
Evolutionarily conserved pathways of energetic connectivity in protein families | Q29615037 | ||
Classical electrostatics in biology and chemistry | Q29615082 | ||
The penultimate rotamer library | Q29615941 | ||
Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states. | Q30168361 | ||
Exploring the conformational space of protein side chains using dead-end elimination and the A* algorithm | Q31996404 | ||
Computational design of antibody-affinity improvement beyond in vivo maturation | Q33576857 | ||
Multiple antiviral activities of cyanovirin-N: blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses | Q33804363 | ||
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy | Q34005185 | ||
The dead-end elimination theorem and its use in protein side-chain positioning | Q34177888 | ||
The anti-HIV cyanovirin-N domain is evolutionarily conserved and occurs as a protein module in eukaryotes. | Q34432278 | ||
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development | Q35137168 | ||
Redesigning the hydrophobic core of a four-helix-bundle protein | Q36278357 | ||
Do salt bridges stabilize proteins? A continuum electrostatic analysis. | Q36278616 | ||
Probing the role of packing specificity in protein design | Q36583764 | ||
In vitro evolution of thermodynamically stable turns | Q36797001 | ||
Enhanced dead-end elimination in the search for the global minimum energy conformation of a collection of protein side chains | Q36799809 | ||
Exploiting the defensive sugars of HIV-1 for drug and vaccine design | Q36802333 | ||
Denatured states of proteins | Q37285327 | ||
A sugar binding protein cyanovirin-N blocks herpes simplex virus type-1 entry and cell fusion | Q37336219 | ||
Computer-aided design of functional protein interactions | Q37617943 | ||
Potent inhibition of HIV-1 fusion by cyanovirin-N requires only a single high affinity carbohydrate binding site: characterization of low affinity carbohydrate binding site knockout mutants | Q38288396 | ||
The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man(8) D1D3 and Man(9) with nanomolar affinity: implications for binding to the HIV envelope protein gp120. | Q38298945 | ||
Analysis of sequence requirements for biological activity of cyanovirin-N, a potent HIV (human immunodeficiency virus)-inactivating protein | Q38343015 | ||
Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus | Q38355197 | ||
Computational models explain the oligosaccharide specificity of cyanovirin-N. | Q38360623 | ||
Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization | Q38361586 | ||
Flipping the switch from monomeric to dimeric CV-N has little effect on antiviral activity | Q40524775 | ||
Recombinant production of cyanovirin-N, a potent human immunodeficiency virus-inactivating protein derived from a cultured cyanobacterium | Q41056025 | ||
Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptide | Q41949099 | ||
Determination of the folding of proteins as a function of denaturants, osmolytes or ligands using circular dichroism | Q42067026 | ||
Using circular dichroism collected as a function of temperature to determine the thermodynamics of protein unfolding and binding interactions | Q42566843 | ||
Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N. | Q43864568 | ||
Transgenic plant production of Cyanovirin-N, an HIV microbicide. | Q44616943 | ||
Thermodynamics and kinetics of non-native interactions in protein folding: a single point mutant significantly stabilizes the N-terminal domain of L9 by modulating non-native interactions in the denatured state | Q44852943 | ||
Deciphering the message in protein sequences: tolerance to amino acid substitutions | Q45038796 | ||
Exploiting the right side of the Ramachandran plot: substitution of glycines by D-alanine can significantly increase protein stability | Q45102646 | ||
Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum | Q45760520 | ||
The dead-end elimination theorem: mathematical aspects, implementation, optimizations, evaluation, and performance | Q45872529 | ||
Protein denaturation: a small-angle X-ray scattering study of the ensemble of unfolded states of cytochrome c. | Q46117814 | ||
Characterization of the unfolding pathway of hen egg white lysozyme | Q46599166 | ||
A mannan binding lectin is involved in cell-cell attachment in a toxic strain of Microcystis aeruginosa | Q46899370 | ||
Structural characterization of an equilibrium unfolding intermediate in cytochrome c. | Q46940734 | ||
Model building of disulfide bonds in proteins with known three-dimensional structure | Q48655269 | ||
Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics. | Q52067139 | ||
On the calculation of electrostatic interactions in proteins. | Q52663973 | ||
A thermodynamic scale for the beta-sheet forming tendencies of the amino acids. | Q53709834 | ||
Discovery of a stable dimeric mutant of cyanovirin-N (CV-N) from a T7 phage-displayed CV-N mutant library | Q56895709 | ||
Dissecting carbohydrate–Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition | Q57904639 | ||
Functional homologs of cyanovirin-N amenable to mass production in prokaryotic and eukaryotic hosts | Q57904660 | ||
Equilibrium and Kinetic Studies on Folding of the Authentic and Recombinant Forms of Human α-Lactalbumin by Circular Dichroism Spectroscopy† | Q58840872 | ||
Rational Modification of Protein Stability by the Mutation of Charged Surface Residues† | Q59600482 | ||
Protein stabilization by removal of unsatisfied polar groups: computational approaches and experimental tests | Q71165654 | ||
Striking stabilization of Arc repressor by an engineered disulfide bond | Q73030400 | ||
Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development | Q81251755 | ||
P433 | issue | 49 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | computational design | Q106195621 |
P304 | page(s) | 10698-10712 | |
P577 | publication date | 2011-11-16 | |
P1433 | published in | Biochemistry | Q764876 |
P1476 | title | Rational and computational design of stabilized variants of cyanovirin-N that retain affinity and specificity for glycan ligands | |
P478 | volume | 50 |