Identification of essential amino acid residues in the functional activity of poliovirus 2A protease

scientific article published on June 1, 1991

Identification of essential amino acid residues in the functional activity of poliovirus 2A protease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0042-6822(91)90602-8
P953full work available at URLhttps://api.elsevier.com/content/article/PII:0042682291906028?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:0042682291906028?httpAccept=text/xml
P698PubMed publication ID1850921

P2093author name stringS. F. Yu
R. E. Lloyd
P2860cites workInhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complexQ67246332
The catalytic role of the active site aspartic acid in serine proteasesQ68176855
Poliovirus protein 3CD is the active protease for processing of the precursor protein P1 in vitroQ69832090
Proteolytic processing of poliovirus polyprotein: elimination of 2Apro-mediated, alternative cleavage of polypeptide 3CD by in vitro mutagenesisQ69839884
Modulation of the expression of poliovirus proteins in reticulocyte lysatesQ70120756
Cleavage of the cap binding protein complex polypeptide p220 is not effected by the second poliovirus protease 2AQ70131052
Cleavage sites in the polypeptide precursors of poliovirus protein P2-XQ72910439
Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implicationsQ24647040
Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoproteaseQ24649662
A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translationQ24650753
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysisQ27728522
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNAQ27861043
Characterization of the catalytic residues of the tobacco etch virus 49-kDa proteinaseQ28238765
Cysteine proteases of positive strand RNA viruses and chymotrypsin-like serine proteases. A distinct protein superfamily with a common structural foldQ30196037
Encephalomyocarditis virus 3C protease: efficient cell-free expression from clones which link viral 5' noncoding sequences to the P3 regionQ33926932
Viral proteinasesQ34164183
Similarity in gene organization and homology between proteins of animal picornaviruses and a plant comovirus suggest common ancestry of these virus familiesQ35444105
Relationship of p220 cleavage during picornavirus infection to 2A proteinase sequencingQ36882082
In vitro translation of poliovirus RNA: utilization of internal initiation sites in reticulocyte lysateQ36915766
Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220.Q36918487
Processing determinants required for in vitro cleavage of the poliovirus P1 precursor to capsid proteinsQ36919254
Poliovirus mutant that does not selectively inhibit host cell protein synthesisQ36950831
Poliovirus protease does not mediate cleavage of the 220,000-Da component of the cap binding protein complexQ37685783
Proteolytic processing of picornaviral polyproteinQ38004542
The use of phosphorothioate-modified DNA in restriction enzyme reactions to prepare nicked DNA.Q40456491
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA.Q40456499
Polypeptide 2A of human rhinovirus type 2: identification as a protease and characterization by mutational analysisQ41268784
A second virus-encoded proteinase involved in proteolytic processing of poliovirus polyprotein.Q42028125
Protein 3CD is the major poliovirus proteinase responsible for cleavage of the P1 capsid precursorQ44133857
Comparative analysis of viral cysteine protease structural modelsQ46124410
Introduction of a cysteine protease active site into trypsinQ46328721
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectessential amino acidQ245282
viral proteinQ952587
PoliovirusQ70923324
P304page(s)615-625
P577publication date1991-06-01
P1433published inVirologyQ7934867
P1476titleIdentification of essential amino acid residues in the functional activity of poliovirus 2A protease
P478volume182