The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity

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The Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.273.22.13669
P698PubMed publication ID9593707

P2093author name stringAktories K
Schmidt G
Selzer J
Lerm M
P2860cites workStructure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogueQ24319143
Three-dimensional structure of a transglutaminase: human blood coagulation factor XIIIQ24564521
Crystal structure of RhoA-GDP and its functional implicationsQ27743848
The small GTPase Rho: cellular functions and signal transductionQ28294633
Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformationQ29618283
Transglutaminase factor XIII uses proteinase-like catalytic triad to crosslink macromoleculesQ30419776
Monoglucosylation of low-molecular-mass GTP-binding Rho proteins by clostridial cytotoxinsQ34290942
Glucosylation of Rho proteins by Clostridium difficile toxin B.Q34312765
Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin stress fibersQ35199228
Protein fold recognition using sequence-derived predictionsQ36279845
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho.Q36604031
Rho as a regulator of the cytoskeleton.Q40403027
Regulation and function of the Rho subfamily of small GTPasesQ40757570
Rho: theme and variationsQ41238352
Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1.Q41532053
Viral proteases: evolution of diverse structural motifs to optimize functionQ41656240
Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.Q42799773
Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine.Q54564124
Molecular localization of the Escherichia coli cytotoxic necrotizing factor CNF1 cell-binding and catalytic domains.Q54564776
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
cytotoxicityQ246181
P304page(s)13669-13674
P577publication date1998-05-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe Rho-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity. Cysteine 866 and histidine 881 are essential for enzyme activity
P478volume273