DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs

scientific article published on July 1997

DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/25.14.2716
P8608Fatcat IDrelease_zghttmx6cjeu5kte6xtbl2vmpy
P932PMC publication ID146802
P698PubMed publication ID9207016
P5875ResearchGate publication ID279403939

P50authorAnthony MaxwellQ37380949
P2093author name stringCove ME
Tingey AP
P2860cites workSite-specific cleavage of DNA by E. coli DNA gyraseQ41062694
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Cloning of the DNA gyrase genes under tac promoter control: overproduction of the gyrase A and B proteinsQ44689610
Minimal DNA requirement for topoisomerase II-mediated cleavage in vitroQ45169409
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs.Q52399144
The complex of DNA gyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase.Q54194852
Mapping the topography of DNA wrapped around gyrase by nucleolytic and chemical probing of complexes of unique DNA sequences.Q54538652
Probing the limits of the DNA breakage-reunion domain of the Escherichia coli DNA gyrase A protein.Q54700296
The intrinsic ATPase of DNA gyraseQ55062440
Studies of the topoisomerase II-mediated cleavage and religation reactions by use of a suicidal double-stranded DNA substrateQ58318876
Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitroQ58318881
The Interaction of Coumarin Antibiotics with Fragments of the DNA Gyrase B Protein†Q59695045
Structure of the DNA gyrase-DNA complex as revealed by transient electric dichroismQ59695104
The DNA dependence of the ATPase activity of DNA gyraseQ59695110
DNA Gyrase: Site-specific Interactions and Transient Double-strand Breakage of DNAQ64390730
Slow interaction of 5'-adenylyl-beta,gamma-imidodiphosphate with Escherichia coli DNA gyrase. Evidence for cooperativity in nucleotide bindingQ67847330
Mechanism of inhibition of DNA gyrase by quinolone antibacterials: specificity and cooperativity of drug binding to DNAQ69352938
Intramolecular and intermolecular DNA ligation mediated by topoisomerase IIQ72109492
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectorsQ26778475
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DNA gyrase binds to the family of prokaryotic repetitive extragenic palindromic sequencesQ33676488
A DNA gyrase-binding site at the center of the bacteriophage Mu genome is required for efficient replicative transpositionQ33887701
Crystal structure of an N-terminal fragment of the DNA gyrase B protein.Q34493198
DNA gyrase: structure and function.Q34507230
A novel suicide substrate for DNA topoisomerases and site-specific recombinasesQ34765037
Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzymeQ35059616
Nalidixic acid resistance: A second genetic character involved in DNA gyrase activityQ35059655
The molecular basis of quinolone actionQ35238284
Contacts between DNA gyrase and its binding site on DNA: features of symmetry and asymmetry revealed by protection from nucleasesQ35319882
Site-specific interaction of DNA gyrase with DNAQ35397299
The binding of gyrase to DNA: analysis by retention by nitrocellulose filtersQ35719264
The partition locus of plasmid pSC101 is a specific binding site for DNA gyraseQ36064962
Conversion of DNA gyrase into a conventional type II topoisomeraseQ37039334
Structure-activity relationships in DNA gyrase inhibitorsQ37902823
Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation eventsQ38323769
New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition siteQ38331894
Inhibitors of DNA gyraseQ38333670
Nuclease protection by Drosophila DNA topoisomerase II. Enzyme/DNA contacts at the strong topoisomerase II cleavage sites.Q38342686
DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complexQ38356745
In the presence of subunit A inhibitors DNA gyrase cleaves DNA fragments as short as 20 bp at specific sitesQ39718939
Effect of pyrimido[1,6-a]benzimidazoles, quinolones, and Ca2+ on the DNA gyrase-mediated cleavage reactionQ39778933
Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprintingQ40399549
Topoisomerase Poisons: Harnessing the Dark Side of Enzyme MechanismQ40476934
The C-terminal domain of the Escherichia coli DNA gyrase A subunit is a DNA-binding proteinQ40532451
The cleavage of DNA at phosphorothioate internucleotidic linkages by DNA gyraseQ40533036
DNA topoisomerases: essential enzymes and lethal targetsQ40678987
DNA gyrase can supercoil DNA circles as small as 174 base pairsQ40818144
DNA gyrase as a drug targetQ40902870
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectquinolonesQ426549
P304page(s)2716-2722
P577publication date1997-07-01
P1433published inNucleic Acids ResearchQ135122
P1476titleDNA gyrase can cleave short DNA fragments in the presence of quinolone drugs
P478volume25