An oligosaccharide at the C-terminus of the F-specific domain in the stalk of the human parainfluenza virus 3 hemagglutinin-neuraminidase modulates fusion

scientific article published on February 2004

An oligosaccharide at the C-terminus of the F-specific domain in the stalk of the human parainfluenza virus 3 hemagglutinin-neuraminidase modulates fusion is …
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scholarly articleQ13442814

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P356DOI10.1016/J.VIRUSRES.2003.11.010
P698PubMed publication ID14749183

P50authorRonald M IorioQ115615679
Anne M MirzaQ115615681
P2093author name stringZhiyu Wang
Jianrong Li
Paul J Mahon
P2860cites workCrystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidaseQ27627919
Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymeraseQ27860943
Deglycosylation of asparagine-linked glycans by peptide:N-glycosidase F.Q34200768
Triggering of human parainfluenza virus 3 fusion protein (F) by the hemagglutinin-neuraminidase (HN) protein: an HN mutation diminishes the rate of F activation and fusionQ34745220
Fusion deficiency induced by mutations at the dimer interface in the Newcastle disease virus hemagglutinin-neuraminidase is due to a temperature-dependent defect in receptor bindingQ35020586
Detection of an interaction between the HN and F proteins in Newcastle disease virus-infected cellsQ35890850
Functional interactions between the fusion protein and hemagglutinin-neuraminidase of human parainfluenza virusesQ36691954
Neutralization map of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus: domains recognized by monoclonal antibodies that prevent receptor recognitionQ36797868
Monoclonal antibodies to newcastle disease virus: delineation of four epitopes on the HN glycoproteinQ36909517
Relative affinity of the human parainfluenza virus type 3 hemagglutinin-neuraminidase for sialic acid correlates with virus-induced fusion activity.Q40047823
Paramyxovirus fusion: a hypothesis for changesQ40767649
Amino acid substitutions in a conserved region in the stalk of the Newcastle disease virus HN glycoprotein spike impair its neuraminidase activity in the globular domainQ40965267
Mutations in the Newcastle disease virus hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusionQ40981026
The role of individual oligosaccharide chains in the activities of the HN glycoprotein of Newcastle disease virusQ41290392
Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spikeQ41338008
Glycosylation within an Antigenic Site on the HN Glycoprotein of Newcastle Disease Virus Interferes with Its Role in the Promotion of Membrane FusionQ41441112
Mutations in the transmembrane domain of the HN protein of Newcastle disease virus affect the structure and activity of the proteinQ41530184
The attachment function of the Newcastle disease virus hemagglutinin-neuraminidase protein can be separated from fusion promotion by mutationQ41563689
Measles virus glycoproteins: studies on the structure and interaction of the haemagglutinin and fusion proteinsQ43916941
Reducing agent-sensitive dimerization of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus correlates with the presence of cysteine at residue 123.Q44072721
Regions on the hemagglutinin-neuraminidase proteins of human parainfluenza virus type-1 and Sendai virus important for membrane fusionQ45782706
A cell fusion-inhibiting monoclonal antibody binds to the presumed stalk domain of the human parainfluenza type 2 virus hemagglutinin-neuraminidase proteinQ45789434
Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virusQ45818684
Molecular cloning and sequence analysis of the human parainfluenza 3 virus genes encoding the surface glycoproteins, F and HN.Q45842279
Functional and neutralization profile of seven overlapping antigenic sites on the HN glycoprotein of Newcastle disease virus: monoclonal antibodies to some sites prevent viral attachmentQ45847117
Genetic variation within a neutralizing domain on the haemagglutinin-neuraminidase glycoprotein of Newcastle disease virusQ45848335
P433issue2
P921main subjectoligosaccharideQ320607
human parainfluenzaQ2051533
P304page(s)177-185
P577publication date2004-02-01
P1433published inVirus ResearchQ15749215
P1476titleAn oligosaccharide at the C-terminus of the F-specific domain in the stalk of the human parainfluenza virus 3 hemagglutinin-neuraminidase modulates fusion
P478volume99

Reverse relations

cites work (P2860)
Q39265580'a'-Position-mutated and G4-mutated hemagglutinin-neuraminidase proteins of Newcastle disease virus impair fusion and hemagglutinin-neuraminidase-fusion interaction by different mechanisms
Q34301817Addition of N-glycans in the stalk of the Newcastle disease virus HN protein blocks its interaction with the F protein and prevents fusion
Q37596488Amino acid substitutions in the F-specific domain in the stalk of the newcastle disease virus HN protein modulate fusion and interfere with its interaction with the F protein
Q24645164Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering
Q42088453Blue native PAGE and biomolecular complementation reveal a tetrameric or higher-order oligomer organization of the physiological measles virus attachment protein H.
Q37743253Decreased dependence on receptor recognition for the fusion promotion activity of L289A-mutated newcastle disease virus fusion protein correlates with a monoclonal antibody-detected conformational change
Q40257990Effects of heptad repeat regions of f protein on the specific membrane fusion in paramyxoviruses
Q36949597Engineered intermonomeric disulfide bonds in the globular domain of Newcastle disease virus hemagglutinin-neuraminidase protein: implications for the mechanism of fusion promotion
Q36994390Envelope protein dynamics in paramyxovirus entry
Q40309457Evidence that maturation of the N-linked glycans of the respiratory syncytial virus (RSV) glycoproteins is required for virus-mediated cell fusion: The effect of alpha-mannosidase inhibitors on RSV infectivity.
Q39026212Functional interaction between paramyxovirus fusion and attachment proteins
Q37713834Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells
Q39900113Glycoprotein interactions in paramyxovirus fusion
Q33782736Influence of the human parainfluenza virus 3 attachment protein's neuraminidase activity on its capacity to activate the fusion protein
Q26750552Measles Virus Fusion Protein: Structure, Function and Inhibition
Q39328806Molecular characterization and phylogenetic analysis of human parainfluenza virus type 3 isolated from Saudi Arabia
Q37644067Molecular determinants defining the triggering range of prefusion F complexes of canine distemper virus
Q91547441Molecular evolution of the hemagglutinin-neuraminidase (HN) gene in human respirovirus 3
Q38744525Multiple Strategies Reveal a Bidentate Interaction between the Nipah Virus Attachment and Fusion Glycoproteins
Q42104014Mutations in the putative dimer-dimer interfaces of the measles virus hemagglutinin head domain affect membrane fusion triggering.
Q41889152Probing the spatial organization of measles virus fusion complexes
Q36949836Residues in the stalk domain of the hendra virus g glycoprotein modulate conformational changes associated with receptor binding
Q45351809Role of N-linked glycosylation of the human parainfluenza virus type 3 hemagglutinin-neuraminidase protein
Q28547034Sequential conformational changes in the morbillivirus attachment protein initiate the membrane fusion process
Q35956606Structural rearrangements of the central region of the morbillivirus attachment protein stalk domain trigger F protein refolding for membrane fusion
Q27673665Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein
Q35826179The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit
Q39375677The second receptor binding site of the globular head of the Newcastle disease virus hemagglutinin-neuraminidase activates the stalk of multiple paramyxovirus receptor binding proteins to trigger fusion
Q36298475Theoretical investigation on the binding specificity of sialyldisaccharides with hemagglutinins of influenza A virus by molecular dynamics simulations
Q35582400Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry

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