C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts

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C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts is …
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scholarly articleQ13442814

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P356DOI10.1165/RCMB.4892
P8608Fatcat IDrelease_vh2qv4yrtrgl3lsoiyfaj35hmm
P698PubMed publication ID12760970

P2093author name stringMasatomo Mori
Kunio Dobashi
Tsugio Nakazawa
Tamotsu Ishizuka
Mitsuyoshi Utsugi
Yasuo Shimizu
Ken Masubuchi
P2860cites workSmad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcriptionQ24311810
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanismQ24600173
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TGFbeta signaling in growth control, cancer, and heritable disordersQ28142605
Transforming growth factor beta in tissue fibrosisQ28239292
Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to developmentQ28268881
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinaseQ28364720
Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during developmentQ28508666
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient miceQ28509000
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivoQ28609356
How MAP kinases are regulatedQ28609360
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1Q29620495
Contribution of small GTPase Rho and its target protein rock in a murine model of lung fibrosisQ32033022
Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10Q33236833
The CCN family of angiogenic regulators: the integrin connectionQ33545691
Mast cell tumor necrosis factor alpha production is regulated by MEK kinasesQ36184530
Des-Arg(10)-kallidin engagement of the B1 receptor stimulates type I collagen synthesis via stabilization of connective tissue growth factor mRNA.Q40884680
TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2.Q40901197
TGF-beta and glomerulonephritis: anti-inflammatory versus prosclerotic actionsQ41462480
Connective tissue growth factor: a mediator of TGF-beta action on fibroblastsQ41700398
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.Q42492769
CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signalingQ42498294
Signaling events required for transforming growth factor-beta stimulation of connective tissue growth factor expression by cultured human lung fibroblastsQ43775382
P433issue6
P921main subjectconnective tissueQ25615
P304page(s)754-761
P577publication date2003-06-01
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleC-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts
P478volume28