Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats.

scientific article

Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1113/JPHYSIOL.2009.169045
P932PMC publication ID2714028
P698PubMed publication ID19403617
P5875ResearchGate publication ID24378465

P50authorPatricia C. LisboaQ79427840
P2093author name stringAnanda Lages Rodrigues
Egberto Gaspar de Moura
Magna Cottini Fonseca Passos
Sheila Cristina Potente Dutra
P2860cites workEffects of a low-calorie diet on resting metabolic rate and serum tri-iodothyronine levels in obese childrenQ77909601
Hypoglycemia per se stimulates sympathetic neural as well as adrenomedullary activity, but, unlike the adrenomedullary response, the forearm sympathetic neural response is not reduced after recent hypoglycemiaQ77948220
[Thyroid hormones and obesity]Q78058822
Temporal evaluation of the thyroid function of rats programmed by leptin treatment on the neonatal periodQ79427842
Neonatal hyperleptinaemia programmes adrenal medullary function in adult rats: effects on cardiovascular parametersQ79545034
Prolactin inhibition in dams during lactation programs for overweight and leptin resistance in adult offspringQ79731188
Maternal low-protein diet during lactation programmes body composition and glucose homeostasis in the adult rat offspringQ80379665
Absence of anorectic effect to acute peripheral leptin treatment in adult rats whose mothers were malnourished during lactationQ80867270
Protein measurement with the Folin phenol reagentQ20900776
Positional cloning of the mouse obese gene and its human homologueQ22251285
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Subclinical hypothyroidism in obese patients: relation to resting energy expenditure, serum leptin, body composition, and lipid profileQ28185736
A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the ratQ28575828
Leptin and the regulation of body weight in mammalsQ29615976
Obesity as a medical problemQ29616305
Effects of the obese gene product on body weight regulation in ob/ob miceQ29617935
Role of leptin in the neuroendocrine response to fastingQ29618866
Resistance to the satiety action of leptin following chronic central leptin infusion is associated with the development of leptin resistance in neuropeptide Y neuronesQ31113757
Multiple signals converging on NF-kappaB.Q33597403
Role of nutritional programming in determining adult morbidityQ33625074
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicityQ33948462
Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.Q34327135
Abnormal splicing of the leptin receptor in diabetic miceQ34379335
Peripheral metabolic actions of leptinQ35018194
Leptin: metabolic control and regulationQ35076921
Circulating leptin and thyroid dysfunctionQ35545624
Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistanceQ35630443
Minireview: A hypothalamic role in energy balance with special emphasis on leptinQ35714911
Postnatal programming of glucocorticoid metabolism in rats modulates high-fat diet-induced regulation of visceral adipose tissue glucocorticoid exposure and sensitivity and adiponectin and proinflammatory adipokines gene expression in adulthoodQ46868132
Low expression of insulin signaling molecules impairs glucose uptake in adipocytes after early overnutritionQ46901819
Acute and chronic leptin effect upon in vivo and in vitro rat thyroid iodide uptakeQ46975201
Leptin serum concentration, food intake and body weight in rats whose mothers were exposed to malnutrition during lactation.Q47180159
Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid functionQ47237643
Excess weight gain during the early postnatal period is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesisQ47286631
The interaction between leptin and the hypothalamic-pituitary-thyroid axisQ47862406
Observations on the orexigenic hypothalamic neuropeptide Y-system in neonatally overfed weanling ratsQ48138624
Perinatal elevation of hypothalamic insulin, acquired malformation of hypothalamic galaninergic neurons, and syndrome x-like alterations in adulthood of neonatally overfed ratsQ48156238
Insulin resistance of hypothalamic arcuate neurons in neonatally overfed ratsQ48170816
Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects.Q48241262
Increased number of galanin-neurons in the paraventricular hypothalamic nucleus of neonatally overfed weanling ratsQ48301714
Differential sulfation and sialylation of secreted mouse thyrotropin (TSH) subunits: regulation by TSH-releasing hormoneQ48319328
Transient neonatal hyperthyroidism results in hypothyroidism in the adult rat.Q48483057
Perinatal overfeeding in rats results in increased levels of plasma leptin but unchanged cerebrospinal leptin in adulthoodQ48486870
The role of leptin in the regulation of TSH secretion in the fed state: in vivo and in vitro studies.Q48559955
Obesity and enhanced diabetes and cardiovascular risk in adult rats due to early postnatal overfeedingQ48572598
Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleusQ48702243
Expression and localization of leptin receptor in the normal rat pituitary glandQ48777071
Thyroid function in fasting rats: variations in 131I uptake and transient decrease in peroxidase activity.Q48970732
Early dietary intervention: long-term effects on blood pressure, brain neuropeptide Y, and adiposity markers.Q49156566
SOCS-3 expression in leptin-sensitive neurons of the hypothalamus of fed and fasted rats.Q51553238
Gender-specific effect of overexpression of sFlt-1 in pregnant mice on fetal programming of blood pressure in the offspring later in life.Q51734953
Acute and delayed effects of a single-dose injection of interleukin-6 on thyroid function in healthy humans.Q52183077
Early postnatal overfeeding and diabetes susceptibility.Q53032134
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced ObesityQ58197140
Influence of early nutrition on growth and adipose tissue characteristics in male and female ratsQ68137118
Effect of triiodothyronine on some metabolic responses of obese patientsQ69273289
Long-term effects of early nutritional experience on the development of obesity in the ratQ71334165
Revised Guide for the Care and Use of Laboratory Animals available. American Physiological SocietyQ71649444
Activation of the hypothalamo-pituitary-adrenal axis in response to septic or non-septic diseases--implications for the euthyroid sick syndromeQ73414592
Overweight and obesity in infants of mothers with long-term insulin-dependent diabetes or gestational diabetesQ73435768
Thyroid function and obesity in children and adolescentsQ73448810
[Relationship between body composition and serum thyroid hormone in children aged 8 to 12 years]Q73921538
Thyroid hormone metabolism in obesityQ74345589
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesityQ35768964
The developmental origins of adult diseaseQ36004074
Loss of leptin actions in obesity: two concepts with cardiovascular implicationsQ36035803
Adipose tissue macrophages.Q36918994
Epigenetic programming of the stress response in male and female rats by prenatal restraint stress.Q37047208
Visceral obesity and the heartQ37059425
Metabolic obesity: the paradox between visceral and subcutaneous fat.Q37065704
Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity.Q37160978
Neonatal programming of neuroimmunomodulation--role of adipocytokines and neuropeptides.Q37264180
Rat thyroid gland expresses the long form of leptin receptors, and leptin stimulates the function of the gland in euthyroid non-fasted animalsQ38293880
Cold exposure restores the decrease in leptin receptors (OB-Rb) caused by neonatal leptin treatment in 30-day-old ratsQ38297128
Gene expression of adrenomedullin, leptin, their receptors and neuropeptide Y in hormone-secreting and non-functioning pituitary adenomas, meningiomas and malignant intracranial tumours in humansQ38298178
Obesity reduced the gene expressions of leptin receptors in hypothalamus and liverQ38300299
Regulation of in vivo TSH secretion by leptinQ38307716
Neonatal leptin treatment programmes leptin hypothalamic resistance and intermediary metabolic parameters in adult rats.Q38314674
Leptin and leptin receptor expression in rat and mouse pituitary cellsQ38316957
Leptin and leptin receptor expression in normal and neoplastic human pituitary: evidence of a regulatory role for leptin on pituitary cell proliferationQ38321766
Induction of uncoupling protein expression in brown and white adipose tissue by leptinQ38329535
Expression of functional leptin receptors in the human ovaryQ38341447
Identification of targets of leptin action in rat hypothalamusQ38353571
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db miceQ38353583
Relation of thyroid hormones to body-weightQ39382422
Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.Q40474479
Leptin regulation of the thyroids: negative regulation on thyroid hormone levels in euthyroid subjects and inhibitory effects on iodide uptake and Na+/I- symporter mRNA expression in rat FRTL-5 cellsQ40518425
Leptin, nutrition, and the thyroid: the why, the wherefore, and the wiringQ40716841
Tumor necrosis factor, ceramide, transforming growth factor-beta1, and aging reduce Na+/I- symporter messenger ribonucleic acid levels in FRTL-5 cellsQ41068415
Inhibition of TSH-induced hydrogen peroxide production by TNF-alpha through a sphingomyelinase signaling pathwayQ41088505
Pituitary-thyroid axis reactivity to hyper- and hypothyroidism in the perinatal period: ontogeny of regulation of regulation and long-term programming of responsesQ41109856
Effects of neonatal hyperthyroidism on the development of the hypothalamic-pituitary-thyroid axis in the rat.Q41601410
Impaired response of UCP family to cold exposure in diabetic (db/db) miceQ42493730
Long-term effects of malnutrition during lactation on the thyroid function of offspringQ43879576
Association between nutrition and gender during lactation influencing glucose homeostasis and blood pressure of the adult offspringQ44181020
Superoxide production in the vasculature of lipopolysaccharide-treated rats and pigsQ44439316
Changes in norepinephrine and epinephrine concentrations in adrenal gland of the rats submitted to acute immobilization stressQ44607552
Prenatal programming of adult thyroid function by alcohol and thyroid hormonesQ44869316
Malnutrition during lactation in rats is associated with higher expression of leptin receptor in the pituitary of adult offspring.Q45098852
Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensivesQ45197869
Postnatal diet-induced obesity in rats upregulates systemic and adipose tissue glucocorticoid metabolism during development and in adulthood: its relationship with the metabolic syndromeQ45199167
Prolactin inhibition in lactating rats changes leptin transfer through the milkQ46542623
Prolactin inhibition at the end of lactation programs for a central hypothyroidism in adult rat.Q46587423
Thyroid function and body weight programming by neonatal hyperthyroidism in rats - the role of leptin and deiodinase activitiesQ46806689
Neonatal low-protein diet changes deiodinase activities and pituitary TSH response to TRH in adult rats.Q46835205
P433issuePt 11
P407language of work or nameEnglishQ1860
P921main subjectovernutritionQ16956975
P304page(s)2647-2661
P577publication date2009-04-29
P1433published inJournal of PhysiologyQ7743612
P1476titlePostnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats
P478volume587

Reverse relations

cites work (P2860)
Q36911312Age and sex dependent effects of early overnutrition on metabolic parameters and the role of neonatal androgens.
Q36283005Challenges and opportunities in developmental integrative physiology
Q37249009Developmental programming in skeletal muscle in response to overnourishment in the immediate postnatal life in rats
Q54314298Early postnatal overnutrition increases adipose tissue accrual in response to a sucrose-enriched diet.
Q38337769Early weaning causes undernutrition for a short period and programmes some metabolic syndrome components and leptin resistance in adult rat offspring.
Q48522572Effects of Ilex paraguariensis (yerba mate) on the hypothalamic signalling of insulin and leptin and liver dysfunction in adult rats overfed during lactation
Q43883160Effects of chronic treadmill training on body mass gain and visceral fat accumulation in overfed rats.
Q36983097Effects of late gestational high-fat diet on body weight, metabolic regulation and adipokine expression in offspring
Q34517644Effects of neonatal overfeeding on juvenile and adult feeding and energy expenditure in the rat.
Q47791271Effects of postnatal overfeeding and fish oil diet on energy expenditure in rats
Q43138215Female mice target deleted for the neuromedin B receptor have partial resistance to diet-induced obesity
Q54966073Fetal over- and undernutrition differentially program thyroid axis adaptability in adult sheep.
Q62089902High Sucrose Intake Ameliorates the Accumulation of Hepatic Triacylglycerol Promoted by Restraint Stress in Young Rats
Q35050357Increase of long-term 'diabesity' risk, hyperphagia, and altered hypothalamic neuropeptide expression in neonatally overnourished 'small-for-gestational-age' (SGA) rats
Q43865990Infant nutrition in relation to eating behaviour and fruit and vegetable intake at age 5 years
Q39303992Long-term effect of altered nutrition induced by litter size manipulation and cross-fostering in suckling male rats on development of obesity risk and health complications
Q35995225Long-term effect of early postnatal overnutrition on insulin resistance and serum fatty acid profiles in male rats
Q38201158Long-term impact of early life events on physiology and behaviour.
Q39034204Low dietary soy isoflavonoids increase hippocampal spine synapse density in ovariectomized rats
Q39573487Maternal high-fat diet induces obesity and adrenal and thyroid dysfunction in male rat offspring at weaning
Q37483208Maternal substrate utilization programs the development of the metabolic syndrome in male mice exposed to high fat in utero
Q28076354Modeling the impact of growth and leptin deficits on the neuronal regulation of blood pressure
Q50556288Neonatal Nicotine Exposure Leads to Hypothalamic Gliosis in Adult Overweight Rats.
Q51053243Neonatal hyperthyroidism on rat heart: interrelation with nitric oxide and sex.
Q34933241Neonatal overfeeding attenuates acute central pro-inflammatory effects of short-term high fat diet
Q87423058Neonatal overfeeding causes higher adrenal catecholamine content and basal secretion and liver dysfunction in adult rats
Q34071494Neonatal overfeeding induced by small litter rearing causes altered glucocorticoid metabolism in rats
Q47686331Neonatal overfeeding leads to developmental programming of adult obesity: you are what you ate.
Q37209168Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats
Q50110683Postnatal overnutrition affects metabolic and vascular function reflected by physiological and histological changes in the aorta of adult Wistar rats
Q35788930Postnatal prebiotic fibre intake mitigates some detrimental metabolic outcomes of early overnutrition in rats
Q39890091Programming of rat adrenal medulla by neonatal hyperleptinemia: adrenal morphology, catecholamine secretion, and leptin signaling pathway
Q41173788Resveratrol treatment rescues hyperleptinemia and improves hypothalamic leptin signaling programmed by maternal high-fat diet in rats.
Q42374228Transient postnatal overfeeding causes liver stress-induced premature senescence in adult mice.
Q90359387miRNA-125b-5p Suppresses Hypothyroidism Development by Targeting Signal Transducer and Activator of Transcription 3