Activation of nuclear factor of activated T cells in a cyclosporin A-resistant pathway

scientific article

Activation of nuclear factor of activated T cells in a cyclosporin A-resistant pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.271.13.7700
P698PubMed publication ID8631809
P5875ResearchGate publication ID14568370

P2093author name stringYoung HA
Ghosh P
Lahesmaa R
Rice NR
Subleski J
Cippitelli M
Sica A
P2860cites workIsolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteinsQ24317724
Characterization of antigen receptor response elements within the interleukin-2 enhancerQ24632042
NF-AT components define a family of transcription factors targeted in T-cell activationQ28114991
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activationQ29620223
CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokinesQ33838538
Identification of a putative regulator of early T cell activation genesQ34171263
T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expressionQ34553481
A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptorQ36353369
Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cellsQ36362494
CD28 signals through acidic sphingomyelinaseQ36364947
Identification of the Immunophilins Capable of Mediating Inhibition of Signal Transduction by Cyclosporin A and FK506: Roles of Calcineurin Binding and Cellular LocationQ36694583
Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulationQ38289894
Graft-versus-host disease in dog and man: the Seattle experienceQ39839309
The B7 and CD28 receptor familiesQ40392461
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin AQ46979889
Nuclear factor of activated T cells contains Fos and Jun.Q54271859
Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol esterQ59083077
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)7700-7704
P577publication date1996-03-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleActivation of nuclear factor of activated T cells in a cyclosporin A-resistant pathway
P478volume271

Reverse relations

cites work (P2860)
Q28610409A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)
Q40966387Attenuation of IL-2 receptor signaling by CD4-ligation requires polymerized cytoskeletal actin but not P56LCK.
Q28141639CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes
Q42230904Ca(2+) -related signaling events influence TLR9-induced IL-10 secretion in human B cells
Q55107300Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway.
Q24671007Cholecystokinin activates pancreatic calcineurin-NFAT signaling in vitro and in vivo
Q41689014Effects of the immunosuppressive drugs CsA and FK506 on intracellular signalling and gene regulation
Q45005986Expression and regulation of NFAT (nuclear factors of activated T cells) in human CD34+ cells: down-regulation upon myeloid differentiation
Q24646521Expression of NFAT-family proteins in normal human T cells
Q78155072Functional expression of the Na/K pump is controlled via a cyclosporin A-sensitive signalling pathway in activated human lymphocytes
Q71814478High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters
Q46501553Interleukin-2-dependent regulation of Na/K pump in human lymphocytes
Q33652150Mechanisms of T-cell activation by human T-cell lymphotropic virus type I.
Q41501375Molecular regulation of cytokine gene expression: interferon-gamma as a model system.
Q28365233Multiple cytokines sharing the common receptor gamma chain can induce CD154/CD40 ligand expression by human CD4+ T lymphocytes via a cyclosporin A-resistant pathway
Q31010956N-substituted benzamides inhibit nuclear factor-kappaB and nuclear factor of activated T cells activity while inducing activator protein 1 activity in T lymphocytes
Q48271310Nuclear translocation of calcineurin Abeta but not calcineurin Aalpha by platelet-derived growth factor in rat aortic smooth muscle
Q34739326Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors
Q35191057The effects of Cyclosporine A and azathioprine on human T cells activated by different costimulatory signals
Q40990128The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway
Q38331306Utilization of an NF-ATp binding promoter element for EGR3 expression in T cells but not fibroblasts provides a molecular model for the lymphoid cell-specific effect of cyclosporin A.

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