review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Hiroo Ueno | Q117281898 |
P2093 | author name string | Keiki Kumano | |
Kiyomichi Tanaka | |||
P2860 | cites work | Notch signaling induces cell cycle arrest in small cell lung cancer cells | Q24291129 |
Notch signaling induces rapid degradation of achaete-scute homolog 1. | Q24293622 | ||
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B | Q24564757 | ||
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland | Q24669531 | ||
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib | Q27824829 | ||
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling | Q27851406 | ||
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer | Q27851410 | ||
Alterations of the Notch pathway in lung cancer. | Q27851544 | ||
EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors. | Q27851590 | ||
Generalized lacZ expression with the ROSA26 Cre reporter strain | Q27860837 | ||
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways | Q28274882 | ||
MicroRNA miR-199a* regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2) | Q28278925 | ||
let-7 and miR-17-92: small-sized major players in lung cancer development | Q28291431 | ||
Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium | Q28588912 | ||
Identification of bronchioalveolar stem cells in normal lung and lung cancer | Q29619267 | ||
Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer | Q33523430 | ||
Alveolar progenitor and stem cells in lung development, renewal and cancer. | Q33579149 | ||
Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim. | Q33618246 | ||
Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells | Q33737442 | ||
MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis | Q33815238 | ||
Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer | Q33863504 | ||
SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity | Q34022836 | ||
Bmi1 expression in long-term germ stem cells | Q34077114 | ||
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells | Q34277248 | ||
The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2. | Q34342864 | ||
EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer | Q34421001 | ||
Interleukin 6, but not T helper 2 cytokines, promotes lung carcinogenesis. | Q34679251 | ||
Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia. | Q34700660 | ||
DNA methylation markers and early recurrence in stage I lung cancer | Q34761286 | ||
Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. | Q34876177 | ||
Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury | Q35032592 | ||
Direct and indirect roles for β-catenin in facultative basal progenitor cell differentiation | Q35850296 | ||
β-Catenin-SOX2 signaling regulates the fate of developing airway epithelium | Q35851532 | ||
Gene-promoter hypermethylation as a biomarker in lung cancer | Q35877182 | ||
Calcitonin driven v-Ha-ras induces multilineage pulmonary epithelial hyperplasias and neoplasms. | Q53420491 | ||
Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers. | Q53529945 | ||
Opposing role of Notch1 and Notch2 in a KrasG12D-driven murine non-small cell lung cancer model | Q57847240 | ||
Disruption of tumor cell adhesion promotes angiogenic switch and progression to micrometastasis in RAF-driven murine lung cancer | Q80783647 | ||
Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer | Q81463886 | ||
Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas | Q36026392 | ||
Mouse models for human lung cancer | Q36071893 | ||
miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. | Q36368456 | ||
Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis | Q36378496 | ||
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer | Q36423456 | ||
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer | Q36568988 | ||
Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis | Q36638089 | ||
Epigenetic field for cancerization | Q36774336 | ||
Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition | Q36905632 | ||
Multicolor lineage tracing methods and intestinal tumors | Q36973379 | ||
Constitutive expression of human keratin 14 gene in mouse lung induces premalignant lesions and squamous differentiation | Q37090686 | ||
Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a | Q37094220 | ||
Multiple roles for Sox2 in the developing and adult mouse trachea | Q37186879 | ||
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK | Q37269941 | ||
Conditional stabilization of beta-catenin expands the pool of lung stem cells | Q37412788 | ||
A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal | Q37582286 | ||
Multiple cells-of-origin of mutant K-Ras-induced mouse lung adenocarcinoma. | Q37687546 | ||
NOTCH1 is required for regeneration of Clara cells during repair of airway injury | Q37734267 | ||
Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53 | Q38453169 | ||
Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma. | Q38461863 | ||
The emerging role of SOX2 in cell proliferation and survival and its crosstalk with oncogenic signaling in lung cancer. | Q39111034 | ||
Notch-1 contributes to epidermal growth factor receptor tyrosine kinase inhibitor acquired resistance in non-small cell lung cancer in vitro and in vivo | Q39115106 | ||
Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma. | Q39187994 | ||
The novel miR-7515 decreases the proliferation and migration of human lung cancer cells by targeting c-Met | Q39255298 | ||
A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer | Q39593316 | ||
Bcl-XL and STAT3 mediate malignant actions of gamma-irradiation in lung cancer cells | Q39724227 | ||
Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells | Q39751974 | ||
A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival | Q39845869 | ||
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations. | Q39916367 | ||
Notch-1 regulates pulmonary neuroendocrine cell differentiation in cell lines and in transgenic mice. | Q40222473 | ||
Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. | Q40543122 | ||
p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration. | Q41669667 | ||
Identification of stem cells that maintain and regenerate lingual keratinized epithelial cells | Q42436810 | ||
Coronary arteries form by developmental reprogramming of venous cells | Q42530831 | ||
E-cadherin controls bronchiolar progenitor cells and onset of preneoplastic lesions in mice | Q42593450 | ||
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation | Q44364520 | ||
Constitutive activation of Notch3 inhibits terminal epithelial differentiation in lungs of transgenic mice | Q47996286 | ||
Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells. | Q51658502 | ||
VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2. | Q53025494 | ||
Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. | Q53241385 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International | Q24082749 |
P433 | issue | 5 | |
P921 | main subject | lung cancer | Q47912 |
lung neoplasm | Q15124212 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 489-496 | |
P577 | publication date | 2015-03-20 | |
2015-05-01 | |||
P1433 | published in | Cancer Science | Q326125 |
P1476 | title | Intracellular signals of lung cancer cells as possible therapeutic targets | |
P478 | volume | 106 |
Q58565363 | Crizotinib presented with promising efficacy but for concomitant mutation in next-generation sequencing-identified ROS1-rearranged non-small-cell lung cancer |
Q54978516 | Establishment of lung cancer patient-derived xenograft models and primary cell lines for lung cancer study. |
Q52569816 | Knockdown of POLDIP2 suppresses tumor growth and invasion capacity and is linked to unfavorable transformation ability and metastatic feature in non-small cell lung cancer. |
Q34530728 | Krüppel-Like Factor 4 Enhances Sensitivity of Cisplatin to Lung Cancer Cells and Inhibits Regulating Epithelial-to-Mesenchymal Transition |
Q92631641 | MiR-1246 Promotes Metastasis and Invasion of A549 cells by Targeting GSK-3β‒Mediated Wnt/β-Catenin Pathway |
Q51266036 | Multifunctional gold nanocomposites designed for targeted CT/MR/optical trimodal imaging of human non-small cell lung cancer cells. |
Q37298676 | SMC4, which is essentially involved in lung development, is associated with lung adenocarcinoma progression |
Q37720250 | Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells |
Q49182439 | The clinical value of miR-193a-3p in non-small cell lung cancer and its potential molecular mechanism explored in silico using RNA-sequencing and microarray data |
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