review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1018428326 |
P356 | DOI | 10.1007/S00011-015-0806-0 |
P698 | PubMed publication ID | 25725697 |
P2093 | author name string | Jing Wang | |
Bing Chen | |||
Yu-Jie Wang | |||
Bao-Zhu Li | |||
Guo-Jun Yang | |||
Jun-Wei Yan | |||
Ya-Nan Wan | |||
Xiao-Lei Huang | |||
P2860 | cites work | Role of IRS-2 in insulin and cytokine signalling | Q24337494 |
The immune pathogenesis of scleroderma: context is everything | Q24633658 | ||
Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation | Q28238669 | ||
IL13RA2 gene polymorphisms are associated with systemic sclerosis | Q28264135 | ||
IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis | Q28285105 | ||
Differentiation potential of CD14+ monocytes into myofibroblasts in patients with systemic sclerosis | Q28731304 | ||
Alternative activation of macrophages: mechanism and functions | Q29614350 | ||
Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension. | Q33649222 | ||
The molecular basis of T helper 1 and T helper 2 cell differentiation | Q34106569 | ||
Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers | Q34249091 | ||
Scleroderma: nomenclature, etiology, pathogenesis, prognosis, and treatments: facts and controversies | Q34353948 | ||
Interleukin-4 and interleukin-13: their similarities and discrepancies | Q34488885 | ||
The discovery, engineering and characterisation of a highly potent anti-human IL-13 fab fragment designed for administration by inhalation. | Q34503422 | ||
Reduced interleukin-4 receptor α expression on CD8+ T cells correlates with higher quality anti-viral immunity | Q34576972 | ||
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis | Q34756244 | ||
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation | Q35083309 | ||
Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-beta in response to fibrogenic stimuli | Q35103031 | ||
GATA-3 up-regulation in CD8+ T cells as a biomarker of immune dysfunction in systemic sclerosis, resulting in excessive interleukin-13 production. | Q54367655 | ||
Evaluation of interleukin 13 polymorphisms in systemic sclerosis. | Q54592869 | ||
Interleukin-10 Gene Promoter and NFKB1 Promoter Insertion/Deletion Polymorphisms in Systemic Sclerosis | Q57987460 | ||
Effector CD8+ T cells in systemic sclerosis patients produce abnormally high levels of interleukin-13 associated with increased skin fibrosis | Q62748342 | ||
Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor | Q71066464 | ||
Expression of interleukin-4 in scleroderma skin specimens and scleroderma fibroblast cultures. Potential role in fibrosis | Q71182942 | ||
Regulation of interleukin-4 on collagen gene expression by systemic sclerosis fibroblasts in culture | Q71549624 | ||
Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis | Q73076887 | ||
Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma | Q73106197 | ||
Interleukin-13 in systemic sclerosis: relationship to nailfold capillaroscopy abnormalities | Q73378880 | ||
Serum levels of tumor necrosis factor and interleukin-13 are elevated in patients with localized scleroderma | Q73812940 | ||
The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action | Q77401459 | ||
Interleukin 4 co-stimulates the PDGF-BB- and bFGF-mediated proliferation of mesangial cells and myofibroblasts | Q78425901 | ||
Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13 | Q79074366 | ||
Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis | Q81377104 | ||
Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients | Q83097062 | ||
A pro-fibrotic role for interleukin-4 in cardiac pressure overload | Q83857166 | ||
Serum leptin, resistin and TNF-α levels in patients with systemic sclerosis: the role of adipokines in scleroderma | Q84811598 | ||
Combining gene expression microarray- and cluster analysis with sequence-based predictions to identify regulators of IL-13 in allergy | Q84975677 | ||
HLA-G5 induces IL-4 secretion critical for successful pregnancy through differential expression of ILT2 receptor on decidual CD4⁺ T cells and macrophages | Q87346215 | ||
IL-13 receptors and signaling pathways: An evolving web | Q35110741 | ||
The function role of GATA-3 in Th1 and Th2 differentiation. | Q35208763 | ||
Treatment with imatinib results in reduced IL-4-producing T cells, but increased CD4(+) T cells in the broncho-alveolar lavage of patients with systemic sclerosis | Q35566387 | ||
Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity | Q35624378 | ||
Systemic sclerosis: a prototypic multisystem fibrotic disorder | Q35649427 | ||
Fibrotic disease and the T(H)1/T(H)2 paradigm | Q35852270 | ||
Interspecies comparison of human and murine scleroderma reveals IL-13 and CCL2 as disease subset-specific targets | Q35952040 | ||
Biochemical and Genetic Evidence for a SAP-PKC-θ Interaction Contributing to IL-4 Regulation | Q36174537 | ||
How are T(H)2-type immune responses initiated and amplified? | Q36394985 | ||
IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages | Q36501243 | ||
IL-13 receptor isoforms: breaking through the complexity | Q36909673 | ||
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity | Q36946566 | ||
IL-13-producing Th1 and Th17 cells characterize adaptive responses to both self and foreign antigens | Q37262658 | ||
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways | Q37358425 | ||
Role of IL-13 in systemic sclerosis | Q37932807 | ||
Cytokine modulation by endothelin-1 and possible therapeutic implications in systemic sclerosis | Q37973213 | ||
Interleukin 6 in systemic sclerosis and potential implications for targeted therapy | Q38002843 | ||
T cells in systemic sclerosis: a reappraisal | Q38009282 | ||
Update on stem cell transplantation for systemic sclerosis: recent trial results | Q38091659 | ||
Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. | Q38309766 | ||
The association of the cytoplasmic domains of interleukin 4 receptor alpha and interleukin 13 receptor alpha 2 regulates interleukin 4 signaling | Q39093135 | ||
Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping | Q39416033 | ||
SHIP represses Th2 skewing by inhibiting IL-4 production from basophils | Q39623829 | ||
Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cells | Q40444779 | ||
IL-4-induced macrophage-derived IGF-I protects myofibroblasts from apoptosis following growth factor withdrawal | Q40524540 | ||
Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma | Q41005869 | ||
Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4 | Q41020866 | ||
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). | Q42101278 | ||
Supernatants from culture of type I collagen-stimulated PBMC from patients with cutaneous systemic sclerosis versus localized scleroderma demonstrate suppression of MMP-1 by fibroblasts | Q42180802 | ||
Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression | Q43752975 | ||
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent | Q44007756 | ||
Dual roles of IL-4 in lung injury and fibrosis | Q44306912 | ||
Molecular mechanisms of interleukin-4-induced up-regulation of type I collagen gene expression in murine fibroblasts. | Q44400944 | ||
Interleukin-4 and interleukin-13 signaling connections maps | Q44469051 | ||
Potential Action of IL-4 and IL-13 as Fibrogenic Factors on Lung Fibroblasts in vitro | Q44644231 | ||
Equilibrium and kinetic analysis of human interleukin-13 and IL-13 receptor alpha-2 complex formation | Q45354358 | ||
Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma. | Q46270782 | ||
Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement | Q46474228 | ||
Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway | Q46484361 | ||
Monocyte chemoattractant protein 1 released from glycosaminoglycans mediates its profibrotic effects in systemic sclerosis via the release of interleukin-4 from T cells | Q46872987 | ||
Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming. | Q51556618 | ||
Platelet-derived growth factor mediates interleukin-13-induced collagen I production in mouse airway fibroblasts. | Q51704419 | ||
P433 | issue | 3-4 | |
P304 | page(s) | 151-159 | |
P577 | publication date | 2015-03-01 | |
P1433 | published in | Inflammation Research | Q1819367 |
P1476 | title | Role of anti-inflammatory cytokines IL-4 and IL-13 in systemic sclerosis | |
P478 | volume | 64 |
Q47133710 | Asperlin Inhibits LPS-Evoked Foam Cell Formation and Prevents Atherosclerosis in ApoE-/- Mice |
Q90678059 | Cytokines and inflammation in adipogenesis: an updated review |
Q90746626 | Hierarchical control of interleukin 13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11 |
Q92000973 | IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis |
Q38829766 | Interleukin-9 and T helper type 9 cells in rheumatic diseases. |
Q64889226 | M2 macrophage-mediated interleukin-4 signalling induces myofibroblast phenotype during the progression of benign prostatic hyperplasia. |
Q38607431 | Macrophage polarization: the link between inflammation and related diseases |
Q58796921 | NRF2 Activation Inhibits Both TGF-1- and IL-13-Mediated Periostin Expression in Fibroblasts: Benefit of Cinnamaldehyde for Antifibrotic Treatment |
Q38622042 | Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis. |
Q39233347 | Protein Tyrosine Phosphatases in Systemic Sclerosis: Potential Pathogenic Players and Therapeutic Targets. |
Q50662045 | Quantification of Inflammatory Markers in Laryngotracheal Stenosis. |
Q38869606 | Regulatory T Cells in Systemic Sclerosis: a Comprehensive Review |
Q97420826 | The Role of Endogenous Eicosapentaenoic Acid and Docosahexaenoic Acid-Derived Resolvins in Systemic Sclerosis |
Q64897993 | The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review. |
Q92040299 | p75 neurotrophin receptor regulates NGF-induced myofibroblast differentiation and collagen synthesis through MRTF-A |
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