Antibody-mediated rejection in pediatric kidney transplantation: pathophysiology, diagnosis, and management

scientific article published on April 2015

Antibody-mediated rejection in pediatric kidney transplantation: pathophysiology, diagnosis, and management is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P6179Dimensions Publication ID1042323299
P356DOI10.1007/S40265-015-0369-Y
P698PubMed publication ID25813498

P2093author name stringMinnie M Sarwal
Manpreet Singh
Yolanda W Ng
P2860cites workProtein microarrays discover angiotensinogen and PRKRIP1 as novel targets for autoantibodies in chronic renal diseaseQ24320230
Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling.Q53924174
Plasmapheresis and intravenous immune globulin provides effective rescue therapy for refractory humoral rejection and allows kidneys to be successfully transplanted into cross-match-positive recipients.Q55034268
The Role of Toll‐Like Receptors in Herpes Simplex Infection in NeonatesQ57636327
Incidence of pneumonitis in patients with non-Hodgkin lymphoma receiving chemoimmunotherapy with rituximabQ57903178
Eculizumab and Splenectomy as Salvage Therapy for Severe Antibody-Mediated Rejection After HLA–Incompatible Kidney TransplantationQ58048136
Posttransplant Soluble B-Cell Activating Factor Kinetics in Pediatric Recipients of First Kidney AllograftQ58620392
The Banff 97 working classification of renal allograft pathologyQ59314413
Investigation of polyomaviruses replication in pediatric patients with nephropathy receiving rituximabQ61716538
The vascular endothelial cell antigen systemQ69939809
Report of the Third Banff Conference on Allograft Pathology (July 20-24, 1995) on classification and lesion scoring in renal allograft pathologyQ71111053
Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulationsQ73138493
Hyperacute rejections of two consecutive renal allografts and early loss of the third transplant caused by non-HLA antibodies specific for endothelial cellsQ74317809
Post transplant development of MICA and anti-HLA antibodies is associated with acute rejection episodes and renal allograft lossQ80225059
Rituximab therapy for acute humoral rejection after kidney transplantationQ80318231
Campath and renal transplant rejectionQ80935782
Non-HLA antibodies after rejection of HLA identical kidney transplantsQ80952235
Antibodies against MICA antigens and kidney-transplant rejectionQ81357717
Non-HLA transplantation immunity revealed by lymphocytotoxic antibodiesQ81706493
Campath-1H use in pediatric renal transplantationQ81737693
A randomized, prospective trial of rituximab for acute rejection in pediatric renal transplantationQ82026577
Successful treatment of chronic antibody-mediated rejection with IVIG and rituximab in pediatric renal transplant recipientsQ82588311
Acute antibody-mediated rejection in paediatric renal transplant recipientsQ83774038
Outcome of subclinical antibody-mediated rejection in kidney transplant recipients with preformed donor-specific antibodiesQ84581805
Terminal complement inhibition decreases antibody-mediated rejection in sensitized renal transplant recipientsQ84977614
De Novo Donor-Specific Human Leukocyte Antigen Antibodies in Nonsensitized Kidney Transplant Recipients After T Cell-Mediated RejectionQ85846370
The impact of non-HLA antibodies directed against endothelin-1 type A receptors (ETAR) on early renal transplant outcomesQ86635362
Histopathologic features of transplant glomerulopathy associated with response to therapy with intravenous immune globulin and rituximabQ87378832
Significance of C1q-fixing donor-specific antibodies after kidney transplantationQ87491598
Protective immunity and use of bortezomib for antibody-mediated rejection in a pediatric kidney transplant recipientQ87665378
Benefits of rituximab combined with intravenous immunoglobulin for desensitization in kidney transplant recipientsQ87763662
Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody productionQ46270888
Intravenous immunoglobulin suppression of HLA alloantibody in highly sensitized transplant candidates and transplantation with a histoincompatible organQ46321287
Reduction of alloantibodies via proteasome inhibition in cardiac transplantation.Q46367397
Efficacy of bortezomib for reducing donor-specific antibodies in children and adolescents on a steroid minimization regimenQ46402292
Campath-1H as rescue therapy for the treatment of acute rejection in kidney transplant patientsQ46554252
Hyperacute allograft rejection mediated by anti-vascular endothelial cell antibodies with a negative monocyte crossmatchQ46612734
Rituximab removes intrarenal B cell clusters in patients with renal vascular allograft rejectionQ46913121
Significance of the positive crossmatch test in kidney transplantationQ47800073
Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejectionQ47869308
Clinical relevance of pretransplant anti-HLA donor-specific antibodies: does C1q-fixation matter?Q47880758
Phenotypic evaluation of B-cell subsets after rituximab for treatment of acute renal allograft rejection in pediatric recipients.Q51016846
Reference values for B cell subpopulations from infancy to adulthoodQ51036853
Antibody mediated rejection associated with complement factor h-related protein 3/1 deficiency successfully treated with eculizumab.Q51333222
Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss.Q51736686
Increased intragraft rejection-associated gene transcripts in patients with donor-specific antibodies and normal biopsies.Q53060554
The use of antibody to complement protein C5 for salvage treatment of severe antibody-mediated rejectionQ28299356
Androgens alter T-cell immunity by inhibiting T-helper 1 differentiationQ28655545
Introduction and overview of therapeutic apheresisQ30451703
Bortezomib provides effective therapy for antibody- and cell-mediated acute rejectionQ33382552
A summary of bortezomib use in transplantation across 29 centersQ33389915
The role of proteasome inhibition with bortezomib in the treatment of antibody-mediated rejection after kidney-only or kidney-combined organ transplantationQ33392607
Eculizumab for the treatment of de novo thrombotic microangiopathy post simultaneous pancreas-kidney transplantation--a case reportQ33395870
Report of the inefficacy of eculizumab in two cases of severe antibody-mediated rejection of renal graftsQ33415390
Use of bortezomib as anti-humoral therapy in kidney transplantationQ33627580
T-cell function in newborn mice and humansQ33667803
Differentially Expressed RNA from Public Microarray Data Identifies Serum Protein Biomarkers for Cross-Organ Transplant Rejection and Other ConditionsQ33707373
Maturation of innate responses to mycobacteria over the first nine months of lifeQ33723428
Gene-expression profiling for rejection surveillance after cardiac transplantationQ34111639
Cytokine regulation of immunoglobulin secretion by neonatal lymphocytesQ34199215
Neonatal and early life vaccinologyQ34248891
Development of interleukin-12-producing capacity throughout childhoodQ34259946
Molecular microscope strategy to improve risk stratification in early antibody-mediated kidney allograft rejection.Q34260097
International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathologyQ34354852
The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART studyQ34489123
Clinicopathologic characteristics of post-transplant lymphoproliferative disorders.Q34489650
Detection of C3d-binding donor-specific anti-HLA antibodies at diagnosis of humoral rejection predicts renal graft loss.Q35027253
Bortezomib for acute antibody-mediated rejection in liver transplantationQ35538969
Endothelial cell antibodies associated with novel targets and increased rejectionQ35550551
Infectious complications in kidney-transplant recipients desensitized with rituximab and intravenous immunoglobulinQ35664634
Immune profile of pediatric renal transplant recipients following alemtuzumab inductionQ35720801
Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipientsQ35730607
Post-transplant therapy with high-dose intravenous gammaglobulin: Applications to treatment of antibody-mediated rejectionQ36078696
Subclinical inflammation and chronic renal allograft injury in a randomized trial on steroid avoidance in pediatric kidney transplantationQ36281955
The clinical impact of humoral immunity in pediatric renal transplantation.Q36719246
The utility of splenectomy as rescue treatment for severe acute antibody mediated rejectionQ36772871
Circulating anti-endothelial cell antibodies are associated with poor outcome in renal allograft recipients with acute rejectionQ36843420
Complete steroid avoidance is effective and safe in children with renal transplants: a multicenter randomized trial with three-year follow-upQ36926228
Relevance of MICA and other non-HLA antibodies in clinical transplantationQ37233488
A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantationQ37246506
Age related differences in dynamics of specific memory B cell populations after clinical pertussis infectionQ37472929
Endothelial transcripts uncover a previously unknown phenotype: C4d-negative antibody-mediated rejectionQ37654098
Proteasome inhibition with bortezomib: an effective therapy for severe antibody mediated rejection after renal transplantation.Q37989270
The influence of bortezomib on donor specific antibody reduction in patients with antibody mediated rejection.Q38023468
The use of bortezomib as a rescue treatment for acute antibody-mediated rejection: report of three cases and review of literatureQ38063607
Post-transplant lymphoproliferative disease in pediatric solid organ transplant recipientsQ38117179
Biomarkers of tolerance.Q38120394
An updated Banff schema for diagnosis of antibody-mediated rejection in renal allograftsQ38210431
A Systematic Review and Meta-Analysis of Rituximab in Antibody-mediated Renal Allograft RejectionQ38228333
Intensive plasmapheresis and intravenous immunoglobulin for treatment of antibody-mediated rejection after kidney transplantQ38237202
Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genesQ39712114
Comparison between bortezomib and rituximab in the treatment of antibody-mediated renal allograft rejection.Q39716270
Vascular endothelial alloantigens in renal transplantationQ39826164
Banff 07 classification of renal allograft pathology: updates and future directionsQ40121163
Efficient priming of antigen-specific cytotoxic T lymphocytes by human cord blood dendritic cellsQ40633802
The identification of novel potential injury mechanisms and candidate biomarkers in renal allograft rejection by quantitative proteomicsQ41926369
Pretransplant Epstein-Barr virus serostatus and incidence of posttransplant lymphoproliferative disorder in pediatric renal transplants.Q42279824
Acute antibody-mediated rejection in pediatric kidney transplants: a single center experienceQ42280145
Rapid reduction in donor-specific anti-human leukocyte antigen antibodies and reversal of antibody-mediated rejection with bortezomib in pediatric heart transplant patientsQ42656427
A peripheral blood diagnostic test for acute rejection in renal transplantation.Q42848519
Eculizumab, bortezomib and kidney paired donation facilitate transplantation of a highly sensitized patient without vascular accessQ42968367
Bortezomib alone fails to decrease donor specific anti-HLA antibodies: 4 case reports.Q43044466
Treatment of simultaneous acute antibody-mediated rejection and acute cellular rejection with alemtuzumab in kidney transplantation: a case reportQ43079825
Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejectionQ43166691
HLA-specific antibodies developed in the first year posttransplant are predictive of chronic rejection and renal graft lossQ43288501
Antibody-mediated microcirculation injury is the major cause of late kidney transplant failureQ43918875
A single low-fixed dose of rituximab to salvage renal transplants from refractory antibody-mediated rejectionQ44197767
The endotoxin-induced increase of cytokines is followed by an increase of cortisol relative to dehydroepiandrosterone (DHEA) in healthy male subjectsQ44214400
Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cellsQ44368031
Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejectionQ44469234
The effects of androstenediol and dehydroepiandrosterone on the immune response to BCG at pubertyQ44504717
Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H).Q44514934
Antibody-mediated rejection and treatment in pediatric patients: one center's experience.Q44519214
Late antibody-mediated rejection in renal allografts: outcome after conventional and novel therapies.Q44533720
Rituximab as treatment for refractory kidney transplant rejectionQ44899030
Refined characterization and reference values of the pediatric T- and B-cell compartmentsQ45191073
Impact of rituximab therapy for treatment of acute humoral rejectionQ45361905
Subclinical cytomegalovirus and Epstein-Barr virus viremia are associated with adverse outcomes in pediatric renal transplantationQ45407225
A common blood gene assay predates clinical and histological rejection in kidney and heart allograftsQ45701579
Plasmapheresis-resistant acute humoral rejection successfully treated with anti-C5 antibodyQ45736192
Epstein-Barr virus-related disorders in children undergoing renal transplantation with tacrolimus-based immunosuppressionQ45746648
Measurement of donor-specific HLA antibodies following plasma exchange therapy predicts clinical outcome in pediatric heart and lung transplant recipients with antibody-mediated rejection.Q45821566
Microarray diagnosis of antibody-mediated rejection in kidney transplant biopsies: an international prospective study (INTERCOM).Q45898843
Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.Q46007205
Operational tolerance in kidney transplantation-improved terminology may enable more precise investigation.Q46023490
Complement-binding anti-HLA antibodies and kidney-allograft survivalQ46141053
P433issue5
P921main subjectkidney transplantationQ740909
P304page(s)455-472
P577publication date2015-04-01
P1433published inDrugsQ3040094
P1476titleAntibody-mediated rejection in pediatric kidney transplantation: pathophysiology, diagnosis, and management
P478volume75