scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1517/14728222.2015.1029454 |
P698 | PubMed publication ID | 25818846 |
P50 | author | George Perry | Q5543353 |
P2093 | author name string | Atsushi Takeda | |
Haruna Tamano | |||
P2860 | cites work | ZnT-3, a putative transporter of zinc into synaptic vesicles | Q24336868 |
Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice | Q24530682 | ||
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory | Q24645499 | ||
Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake | Q24656613 | ||
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo | Q28131779 | ||
A specific amyloid-beta protein assembly in the brain impairs memory | Q28854597 | ||
Alzheimer's disease: the amyloid cascade hypothesis | Q29547160 | ||
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins | Q29547593 | ||
Alzheimer's disease is a synaptic failure | Q29547670 | ||
Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function | Q29614851 | ||
Core candidate neurochemical and imaging biomarkers of Alzheimer's disease | Q31162752 | ||
Effect of metals on kinetic pathways of amyloid-β aggregation | Q33649803 | ||
Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4 | Q33857787 | ||
Molecular mechanisms of neurodegeneration in Alzheimer's disease | Q33871297 | ||
The galvanization of beta-amyloid in Alzheimer's disease | Q34063386 | ||
Zn(2+): a novel ionic mediator of neural injury in brain disease. | Q34069624 | ||
Transient increase in Zn2+ in hippocampal CA1 pyramidal neurons causes reversible memory deficit | Q34098272 | ||
Alzheimer's disease: cell-specific pathology isolates the hippocampal formation | Q34261572 | ||
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial | Q34283745 | ||
Synaptic plasticity, memory and the hippocampus: a neural network approach to causality. | Q34727978 | ||
Molecular dynamics study of Zn(aβ) and Zn(aβ)2 | Q35004603 | ||
Modulation of mitochondrial function by endogenous Zn2+ pools. | Q35023020 | ||
Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity | Q35109915 | ||
Amyloid β-mediated Zn2+ influx into dentate granule cells transiently induces a short-term cognitive deficit | Q35533112 | ||
The neurophysiology and pathology of brain zinc | Q35572191 | ||
Advances in the early detection of Alzheimer's disease | Q35857470 | ||
The neurobiology of zinc in health and disease | Q36126098 | ||
Amyloid beta peptides and glutamatergic synaptic dysregulation | Q37021970 | ||
Prediction of AD with MRI-based hippocampal volume in mild cognitive impairment | Q37313709 | ||
Insight into zinc signaling from dietary zinc deficiency | Q37595845 | ||
Zinc in the physiology and pathology of the CNS. | Q37614216 | ||
Zinc signaling in the hippocampus and its relation to pathogenesis of depression | Q37821365 | ||
Molecular and genetic features of zinc transporters in physiology and pathogenesis. | Q37874950 | ||
Molecular mechanisms of amyloid oligomers toxicity | Q38005284 | ||
Synaptic Zn(2+) homeostasis and its significance | Q38083017 | ||
Biometals and their therapeutic implications in Alzheimer's disease. | Q38263669 | ||
Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer's disease | Q38966279 | ||
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial | Q40064054 | ||
The role of zinc in Alzheimer's disease | Q41488419 | ||
Life and death of neurons in the aging brain | Q41614205 | ||
Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits. | Q41843219 | ||
Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors | Q42738430 | ||
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses | Q43158585 | ||
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers | Q43509033 | ||
Distribution of the zinc transporter ZnT-1 in comparison with chelatable zinc in the mouse brain | Q43976769 | ||
Effects of the neurotrophic agent T-817MA on oligomeric amyloid-β-induced deficits in long-term potentiation in the hippocampal CA1 subfield | Q44510610 | ||
ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc. | Q45066353 | ||
A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses. | Q46064935 | ||
Early histological maturation in the hippocampus of the guinea pig. | Q46283586 | ||
ß-amyloid-related peptides potentiate K+-evoked glutamate release from adult rat hippocampal slices | Q46344859 | ||
Amyloid beta prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation | Q46641415 | ||
Insights into Zn2+ homeostasis in neurons from experimental and modeling studies | Q46815661 | ||
Inhibition of presynaptic activity by zinc released from mossy fiber terminals during tetanic stimulation | Q46846005 | ||
Concentrations of extracellular free zinc (pZn)e in the central nervous system during simple anesthetization, ischemia and reperfusion | Q46916576 | ||
Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model. | Q47305370 | ||
Soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning | Q48262827 | ||
Copper, iron and zinc in Alzheimer's disease senile plaques | Q48429285 | ||
Responsiveness to kainate in young rats after 2-week zinc deprivation | Q48435320 | ||
beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons. | Q48463841 | ||
Age-related changes of sulphide-silver staining in the rat hippocampus | Q48523347 | ||
Zinquin identifies subcellular compartmentalization of zinc in cortical neurons. Relation to the trafficking of zinc and the mitochondrial compartment | Q48596909 | ||
Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity | Q48649595 | ||
Intracellular Zn(2+) signaling in the dentate gyrus is required for object recognition memory | Q48686158 | ||
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment | Q48694961 | ||
The primate hippocampal formation: evidence for a time-limited role in memory storage | Q48879853 | ||
Dependence of the histofluorescently reactive zinc pool on zinc transporter-3 in the normal brain | Q48904299 | ||
Efficacy and toxicity of clioquinol treatment and A-beta42 inoculation in the APP/PSI mouse model of Alzheimer's disease. | Q51032498 | ||
Cerebrospinal fluid trace element content in dementia: clinical, radiologic, and pathologic correlations. | Q53198014 | ||
Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species. | Q53291427 | ||
Rapid induction of Alzheimer A beta amyloid formation by zinc. | Q53316140 | ||
Prediction of Alzheimer's disease in mild cognitive impairment: a prospective study in Taiwan. | Q53375835 | ||
Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide. | Q55066167 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 1051-1058 | |
P577 | publication date | 2015-03-27 | |
P1433 | published in | Expert Opinion on Therapeutic Targets | Q5421214 |
P1476 | title | Regulation of extracellular Zn(2+) homeostasis in the hippocampus as a therapeutic target for Alzheimer's disease | |
P478 | volume | 19 |
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