Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens

scientific article published on 07 June 2017

Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/JACS.7B02716
P953full work available at URLhttps://europepmc.org/articles/pmc5617735?pdf=render
P932PMC publication ID5617735
P698PubMed publication ID28590725

P7228access restriction statusopen accessQ232932
P50authorMohammad SeyedsayamdostQ88479944
P2093author name stringFei Xu
Kyuho Moon
Behnam Nazari
Leah B Bushin
P2860cites workComplete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)Q29547307
Bioactive microbial metabolitesQ31157729
Dereplication of peptidic natural products through database search of mass spectraQ33614929
A new family of bacterial regulatory proteinsQ33626593
High-throughput platform for the discovery of elicitors of silent bacterial gene clustersQ33665547
How to discover new antibiotics: harvesting the parvomeQ33757045
Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile.Q33927147
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilisQ33965431
Genetic factors that influence moenomycin production in streptomycetesQ34127518
Natural products: a continuing source of novel drug leadsQ34328933
Biosynthetic Gene Cluster for Surugamide A Encompasses an Unrelated Decapeptide, Surugamide FQ87968440
Chemical perturbation of secondary metabolism demonstrates important links to primary metabolismQ34393211
Natural Products as Sources of New Drugs from 1981 to 2014.Q34512692
Genomic basis for natural product biosynthetic diversity in the actinomycetesQ34711979
Extending the classification of bacterial transcription factors beyond the helix-turn-helix motif as an alternative approach to discover new cis/trans relationships.Q35618547
GntR Family of Bacterial Transcription Factors and Their DNA Binding Motifs: Structure, Positioning and Co-Evolution.Q35685164
xylE functions as an efficient reporter gene in Streptomyces spp.: use for the study of galP1, a catabolite-controlled promoterQ36184566
Are antibiotics naturally antibiotics?Q36428095
New antibiotics from bacterial natural productsQ36679241
Antibiotics as signalling moleculesQ36732540
Trading molecules and tracking targets in symbiotic interactionsQ37222223
Mixed fermentation for natural product drug discoveryQ37420501
Impact of natural products on developing new anti-cancer agentsQ37473373
Insights into naturally minimised Streptomyces albus J1074 genome.Q37608801
Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clustersQ37751993
The regulation of the secondary metabolism of Streptomyces: new links and experimental advancesQ37879562
Antibiotics as signal molecules.Q37904976
Streptomyces as symbionts: an emerging and widespread theme?Q37957174
New strategies for drug discovery: activation of silent or weakly expressed microbial gene clustersQ38059156
Triggers and cues that activate antibiotic production by actinomycetesQ38125903
Bacterial symbionts in agricultural systems provide a strategic source for antibiotic discoveryQ38127133
Activating secondary metabolism with stress and chemicalsQ38170294
Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters.Q38459251
Discovery of microbial natural products by activation of silent biosynthetic gene clustersQ38539563
Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.Q38832392
Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small moleculesQ38941332
The streptomyces genome contains multiple pseudo-attB sites for the (phi)C31-encoded site-specific recombination systemQ39694905
Strategies for the discovery of new natural products by genome miningQ40398989
Quinolones share a common interaction domain on topoisomerase II with other DNA cleavage-enhancing antineoplastic drugsQ42550867
Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiaeQ42614130
Mansouramycins A-D, cytotoxic isoquinolinequinones from a marine streptomycete.Q43239734
Effect of different classes of inhibitors on DNA gyrase from Mycobacterium smegmatisQ43753561
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs.Q46198377
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.Q48080782
Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis.Q51669780
Novel inhibitors of prolyl 4-hydroxylaseQ67486786
Measurement of induced beta-galactosidase activity in intact cells of Streptomyces speciesQ71557713
Green fluorescent protein as a reporter for spatial and temporal gene expression in Streptomyces coelicolor A3(2)Q73074195
Bacterial death by DNA gyrase poisoningQ77148142
Surugamides A–E, Cyclic Octapeptides with Four d-Amino Acid Residues, from a Marine Streptomyces sp.: LC–MS-Aided Inspection of Partial Hydrolysates for the Distinction of d- and l-Amino Acid Residues in the SequenceQ78329065
P433issue27
P407language of work or nameEnglishQ1860
P921main subjectStreptomyces albusQ7623378
StreptomycesQ1144013
Streptomyces albidoflavusQ22286833
H-DL-Trp-DL-Val-DL-Val-DL-xiThr-Unk-DL-Leu-DL-Val-DL-Ala-DL-Val-DL-Ala-OHQ103816247
cyclo[DL-Ala-DL-Val-DL-Val-DL-Lys-DL-Val-DL-Phe-DL-Leu-DL-Val]Q103817057
N-[4-[8-benzyl-20-butan-2-yl-17-methyl-11-(2-methylpropyl)-3,6,9,12,15,18,21,24-octaoxo-5,14,23-tri(propan-2-yl)-1,4,7,10,13,16,19,22-octazacyclotetracos-2-yl]butyl]-7-(methylamino)-5,8-dioxoisoquinoline-4-carboxamideQ103818850
Albuquinone AQ104169723
Surugamide F2Q104914921
Surugamide IQ104946655
Albucyclone EQ104992453
Albucyclone FQ105142979
Albucyclone CQ105176099
Albucyclone AQ105182180
Albucyclone BQ105184000
Albucyclone DQ105187258
Surugamide HQ105203612
Surugamide GQ105292070
Acyl-surugamide AQ105313259
Surugamide F3Q105345377
Surugamide JQ105365180
Surugamide AQ77372486
P6954online access statusopen accessQ232932
P304page(s)9203-9212
P577publication date2017-06-07
P1433published inJournal of the American Chemical SocietyQ898902
P1476titleDiscovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens
P478volume139

Reverse relations

cites work (P2860)
Q90929349A genetics-free method for high-throughput discovery of cryptic microbial metabolites
Q57822331Activation of microbial secondary metabolic pathways: Avenues and challenges
Q91997787Albumycin, a new isoindolequinone from Streptomyces albus J1074 harboring the fluostatin biosynthetic gene cluster
Q90062296An Isotopic Ratio Outlier Analysis Approach for Global Metabolomics of Biosynthetically Talented Actinomycetes
Q92108268Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria
Q52368924Butenolides from Streptomyces albus J1074 Act as External Signals To Stimulate Avermectin Production in Streptomyces avermitilis.
Q92186698Cebulantin, a Cryptic Lanthipeptide Antibiotic Uncovered Using Bioactivity-Coupled HiTES
Q89065631Chemical Elicitors of Antibiotic Biosynthesis in Actinomycetes
Q98457972Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening
Q52693058Diverse and Abundant Secondary Metabolism Biosynthetic Gene Clusters in the Genomes of Marine Sponge Derived Streptomyces spp. Isolates.
Q90334007Genome Mining Coupled with OSMAC-Based Cultivation Reveal Differential Production of Surugamide A by the Marine Sponge Isolate Streptomyces sp. SM17 When Compared to Its Terrestrial Relative S. albidoflavus J1074
Q62673366Heterologous expression-facilitated natural products’ discovery in actinomycetes
Q64166981Mining for Microbial Gems: Integrating Proteomics in the Postgenomic Natural Product Discovery Pipeline
Q89881628Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis
Q90192470Natural Products as a Foundation for Drug Discovery
Q48149208Novel Bioactive Paulomycin Derivatives Produced by Streptomyces albus J1074.
Q89043822Recent advances in activating silent biosynthetic gene clusters in bacteria
Q92538313Regulation of Antibiotic Production by Signaling Molecules in Streptomyces
Q57093308Response of Hypogean Actinobacterial Genera Secondary Metabolism to Chemical and Biological Stimuli
Q92761494Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes
Q57479721Streptomycetes: Surrogate hosts for the genetic manipulation of biosynthetic gene clusters and production of natural products
Q41670091Though Much Is Taken, Much Abides: Finding New Antibiotics Using Old Ones

Search more.